Application 212028

Type
NDA
Sponsor
EISAI INC

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001DAYVIGOLEMBOREXANTTABLET;ORAL5MGYesNo
002DAYVIGOLEMBOREXANTTABLET;ORAL10MGYesNo

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N212028-001DAYVIGOLEMBOREXANT5MGTABLET / ORALRLD2020-04-07
N212028-002DAYVIGOLEMBOREXANT10MGTABLET / ORALRLD, RS2020-04-07

Orange Book patents#

Current patent rows page 1 of 1 · 8 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N212028-00182688482031-09-20U-2791Drug substance, Drug product2020-05-05
N212028-001101886522035-10-21U-2791Drug product2020-05-05
N212028-001107025292035-10-21Drug product2024-03-22
N212028-001110269442035-10-21Drug product2024-03-22
N212028-00282688482031-09-20U-2791Drug substance, Drug product2020-05-05
N212028-002101886522035-10-21U-2791Drug product2020-05-05
N212028-002107025292035-10-21Drug product2024-03-22
N212028-002110269442035-10-21Drug product2024-03-22

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 2 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N212028-001M-2932026-04-20
N212028-002M-2932026-04-20

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 74 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N212028-001DAYVIGO5MGTABLET / ORALRLD2020-04-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N212028-002DAYVIGO10MGTABLET / ORALRLD, RS2020-04-07011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N212028-001DAYVIGO5MGTABLET / ORALRLD2020-04-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N212028-002DAYVIGO10MGTABLET / ORALRLD, RS2020-04-0731067a03dcf5…
2025-08-23 18:47 UTC2025-08N212028-001DAYVIGO5MGTABLET / ORALRLD2020-04-076a471c1ec25d…
2025-08-23 18:47 UTC2025-08N212028-002DAYVIGO10MGTABLET / ORALRLD, RS2020-04-076a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N212028-001DAYVIGO5MGTABLET / ORALRLD2020-04-07fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N212028-002DAYVIGO10MGTABLET / ORALRLD, RS2020-04-07fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N212028-001DAYVIGO5MGTABLET / ORALRLD2020-04-07b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N212028-002DAYVIGO10MGTABLET / ORALRLD, RS2020-04-07b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N212028-001DAYVIGO5MGTABLET / ORALRLD2020-04-0703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N212028-002DAYVIGO10MGTABLET / ORALRLD, RS2020-04-0703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N212028-001DAYVIGO5MGTABLET / ORALRLD2020-04-072680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N212028-002DAYVIGO10MGTABLET / ORALRLD, RS2020-04-072680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N212028-001DAYVIGO5MGTABLET / ORALRLD2020-04-075bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N212028-002DAYVIGO10MGTABLET / ORALRLD, RS2020-04-075bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N212028-001DAYVIGO5MGTABLET / ORALRLD2020-04-07d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N212028-002DAYVIGO10MGTABLET / ORALRLD, RS2020-04-07d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N212028-001DAYVIGO5MGTABLET / ORALRLD2020-04-07d06236e962d9…
2024-10-29 15:01 UTC2024-10N212028-002DAYVIGO10MGTABLET / ORALRLD, RS2020-04-07d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N212028-001DAYVIGO5MGTABLET / ORALRLD2020-04-0779d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N212028-002DAYVIGO10MGTABLET / ORALRLD, RS2020-04-0779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N212028-001DAYVIGO5MGTABLET / ORALRLD2020-04-07301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N212028-002DAYVIGO10MGTABLET / ORALRLD, RS2020-04-07301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N212028-001DAYVIGO5MGTABLET / ORALRLD2020-04-071e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N212028-002DAYVIGO10MGTABLET / ORALRLD, RS2020-04-071e350fbaab3a…
2024-05-31 18:47 UTC2024-05N212028-001DAYVIGO5MGTABLET / ORALRLD2020-04-078072bd15b7f6…
2024-05-31 18:47 UTC2024-05N212028-002DAYVIGO10MGTABLET / ORALRLD, RS2020-04-078072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N212028-001DAYVIGO5MGTABLET / ORALRLD2020-04-075c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N212028-002DAYVIGO10MGTABLET / ORALRLD, RS2020-04-075c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N212028-001DAYVIGO5MGTABLET / ORALRLD2020-04-075d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N212028-002DAYVIGO10MGTABLET / ORALRLD, RS2020-04-075d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N212028-001DAYVIGO5MGTABLET / ORALRLD2020-04-074b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N212028-002DAYVIGO10MGTABLET / ORALRLD, RS2020-04-074b0b4de00fa7…
2022-03-09 01:35 UTC2022-03N212028-001DAYVIGO5MGTABLET / ORALRLD2020-04-07bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N212028-002DAYVIGO10MGTABLET / ORALRLD, RS2020-04-07bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N212028-001DAYVIGO5MGTABLET / ORALRLD2020-04-07782e0a99824c…
2021-12-28 21:50 UTC2021-12N212028-002DAYVIGO10MGTABLET / ORALRLD, RS2020-04-07782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N212028-001DAYVIGO5MGTABLET / ORALRLD2020-04-0787673890dc5c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N212028-002DAYVIGO10MGTABLET / ORALRLD, RS2020-04-0787673890dc5c…

Observed Orange Book patent history#

Patent history page 1 of 6 · 208 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N212028-00182688482031-09-20U-2791Drug substance, Drug product2020-05-05011fe1cb6892…
2026-02-19 14:30 UTC2026-02N212028-001101886522035-10-21U-2791Drug product2020-05-05011fe1cb6892…
2026-02-19 14:30 UTC2026-02N212028-001107025292035-10-21Drug product2024-03-22011fe1cb6892…
2026-02-19 14:30 UTC2026-02N212028-001110269442035-10-21Drug product2024-03-22011fe1cb6892…
2026-02-19 14:30 UTC2026-02N212028-00282688482031-09-20U-2791Drug substance, Drug product2020-05-05011fe1cb6892…
2026-02-19 14:30 UTC2026-02N212028-002101886522035-10-21U-2791Drug product2020-05-05011fe1cb6892…
2026-02-19 14:30 UTC2026-02N212028-002107025292035-10-21Drug product2024-03-22011fe1cb6892…
2026-02-19 14:30 UTC2026-02N212028-002110269442035-10-21Drug product2024-03-22011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N212028-00182688482031-09-20U-2791Drug substance, Drug product2020-05-0531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N212028-001101886522035-10-21U-2791Drug product2020-05-0531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N212028-001107025292035-10-21Drug product2024-03-2231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N212028-001110269442035-10-21Drug product2024-03-2231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N212028-00282688482031-09-20U-2791Drug substance, Drug product2020-05-0531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N212028-002101886522035-10-21U-2791Drug product2020-05-0531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N212028-002107025292035-10-21Drug product2024-03-2231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N212028-002110269442035-10-21Drug product2024-03-2231067a03dcf5…
2025-08-23 18:47 UTC2025-08N212028-00182688482031-09-20U-2791Drug substance, Drug product2020-05-056a471c1ec25d…
2025-08-23 18:47 UTC2025-08N212028-001101886522035-10-21U-2791Drug product2020-05-056a471c1ec25d…
2025-08-23 18:47 UTC2025-08N212028-001107025292035-10-21Drug product2024-03-226a471c1ec25d…
2025-08-23 18:47 UTC2025-08N212028-001110269442035-10-21Drug product2024-03-226a471c1ec25d…
2025-08-23 18:47 UTC2025-08N212028-00282688482031-09-20U-2791Drug substance, Drug product2020-05-056a471c1ec25d…
2025-08-23 18:47 UTC2025-08N212028-002101886522035-10-21U-2791Drug product2020-05-056a471c1ec25d…
2025-08-23 18:47 UTC2025-08N212028-002107025292035-10-21Drug product2024-03-226a471c1ec25d…
2025-08-23 18:47 UTC2025-08N212028-002110269442035-10-21Drug product2024-03-226a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N212028-00182688482031-09-20U-2791Drug substance, Drug product2020-05-05fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N212028-001101886522035-10-21U-2791Drug product2020-05-05fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N212028-001107025292035-10-21Drug product2024-03-22fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N212028-001110269442035-10-21Drug product2024-03-22fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N212028-00282688482031-09-20U-2791Drug substance, Drug product2020-05-05fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N212028-002101886522035-10-21U-2791Drug product2020-05-05fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N212028-002107025292035-10-21Drug product2024-03-22fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N212028-002110269442035-10-21Drug product2024-03-22fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N212028-00182688482031-09-20U-2791Drug substance, Drug product2020-05-05b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N212028-001101886522035-10-21U-2791Drug product2020-05-05b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N212028-001107025292035-10-21Drug product2024-03-22b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N212028-001110269442035-10-21Drug product2024-03-22b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N212028-00282688482031-09-20U-2791Drug substance, Drug product2020-05-05b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N212028-002101886522035-10-21U-2791Drug product2020-05-05b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N212028-002107025292035-10-21Drug product2024-03-22b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N212028-002110269442035-10-21Drug product2024-03-22b8a1b40f171c…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 3 · 114 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-02-19 14:30 UTC2026-02N212028-001M-2932026-04-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02N212028-002M-2932026-04-20011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N212028-001NCE2025-04-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N212028-001M-2932026-04-2031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N212028-002NCE2025-04-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N212028-002M-2932026-04-2031067a03dcf5…
2025-08-23 18:47 UTC2025-08N212028-001NCE2025-04-076a471c1ec25d…
2025-08-23 18:47 UTC2025-08N212028-001M-2932026-04-206a471c1ec25d…
2025-08-23 18:47 UTC2025-08N212028-002NCE2025-04-076a471c1ec25d…
2025-08-23 18:47 UTC2025-08N212028-002M-2932026-04-206a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N212028-001NCE2025-04-07fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N212028-001M-2932026-04-20fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N212028-002NCE2025-04-07fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N212028-002M-2932026-04-20fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N212028-001NCE2025-04-07b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N212028-001M-2932026-04-20b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N212028-002NCE2025-04-07b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N212028-002M-2932026-04-20b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N212028-001NCE2025-04-0703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N212028-001M-2932026-04-2003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N212028-002NCE2025-04-0703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N212028-002M-2932026-04-2003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N212028-001NCE2025-04-072680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N212028-001M-2932026-04-202680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N212028-002NCE2025-04-072680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N212028-002M-2932026-04-202680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N212028-001NCE2025-04-075bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N212028-001M-2932026-04-205bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N212028-002NCE2025-04-075bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N212028-002M-2932026-04-205bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N212028-001NCE2025-04-07d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N212028-001M-2932026-04-20d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N212028-002NCE2025-04-07d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N212028-002M-2932026-04-20d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N212028-001NCE2025-04-07d06236e962d9…
2024-10-29 15:01 UTC2024-10N212028-001M-2932026-04-20d06236e962d9…
2024-10-29 15:01 UTC2024-10N212028-002NCE2025-04-07d06236e962d9…
2024-10-29 15:01 UTC2024-10N212028-002M-2932026-04-20d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N212028-001NCE2025-04-0779d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N212028-001M-2932026-04-2079d66fd596c7…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
DAYVIGOLEMBOREXANTEisai Inc.7074cb65-77b3-45d2-8e8d-da8dc0f70bfd2025-02-24Warnings, Adverse reactionsExact identifier
application applno (NDA): 212028
application number: NDA212028
ndc (product): 62856-455
ndc (product): 62856-410
ndc (product): 62856-405

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 29 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
62856-405DAYVIGOlemborexantEisai Inc.NDACurrent
62856-405DAYVIGOlemborexantEisai Inc.NDACurrent
62856-405DAYVIGOlemborexantEisai Inc.NDACurrent
62856-405DAYVIGOlemborexantEisai Inc.NDACurrent
62856-405DAYVIGOlemborexantEisai Inc.NDACurrent
62856-405DAYVIGOlemborexantEisai Inc.NDACurrent
62856-405DAYVIGOlemborexantEisai Inc.NDACurrent
62856-405DAYVIGOlemborexantEisai Inc.NDACurrent
62856-405DAYVIGOlemborexantEisai Inc.NDACurrent
62856-405DAYVIGOlemborexantEisai Inc.NDACurrent
62856-410DAYVIGOlemborexantEisai Inc.NDACurrent
62856-410DAYVIGOlemborexantEisai Inc.NDACurrent
62856-410DAYVIGOlemborexantEisai Inc.NDACurrent
62856-410DAYVIGOlemborexantEisai Inc.NDACurrent
62856-410DAYVIGOlemborexantEisai Inc.NDACurrent
62856-410DAYVIGOlemborexantEisai Inc.NDACurrent
62856-410DAYVIGOlemborexantEisai Inc.NDACurrent
62856-410DAYVIGOlemborexantEisai Inc.NDACurrent
62856-410DAYVIGOlemborexantEisai Inc.NDACurrent
62856-410DAYVIGOlemborexantEisai Inc.NDACurrent
62856-455DAYVIGOlemborexantEisai Inc.NDACurrent
62856-455DAYVIGOlemborexantEisai Inc.NDACurrent
62856-455DAYVIGOlemborexantEisai Inc.NDACurrent
62856-455DAYVIGOlemborexantEisai Inc.NDACurrent
62856-455DAYVIGOlemborexantEisai Inc.NDACurrent
62856-455DAYVIGOlemborexantEisai Inc.NDACurrent
62856-455DAYVIGOlemborexantEisai Inc.NDACurrent
62856-455DAYVIGOlemborexantEisai Inc.NDACurrent
62856-455DAYVIGOlemborexantEisai Inc.NDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
81304SUPPL 2025-02-21
81296SUPPL 2025-02-20
81295SUPPL 2025-02-20
74048SUPPL 2023-04-24
74035SUPPL 2023-04-21
73314SUPPL2023-01-30
73313SUPPL2023-01-30
73295SUPPL2023-01-26
70525SUPPL2022-03-15
70524SUPPL2022-03-15
70504SUPPL2022-03-14
68931ORIG2021-10-08
64462SUPPL2020-09-01
64417SUPPL2020-08-25
61713ORIG2020-01-28
61448ORIG2019-12-26
61377ORIG2019-12-23
61376ORIG2019-12-23