Application 213535

Type
NDA
Sponsor
GENENTECH INC

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001EVRYSDIRISDIPLAMPOWDER FOR ORAL SOLUTION1.5MGNoNo

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N213535-001EVRYSDIRISDIPLAM0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-07

Orange Book patents#

Current patent rows page 1 of 1 · 7 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N213535-00195869552033-02-08Drug substance, Drug product2020-09-03
N213535-00199697542035-05-11U-1943Drug substance, Drug product2020-09-03
N213535-001118276462036-01-25U-19432023-12-14
N213535-001119381362036-11-08Drug product2024-04-17
N213535-001123502732038-10-01U-19432025-07-31
N213535-001115344442038-10-04U-19432023-01-25
N213535-001121227892041-04-15Drug substance, Drug product2024-11-12

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 3 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N213535-001M-2702026-10-03
N213535-001ODE-3342027-08-07
N213535-001ODE-4002029-05-27

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-07011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-0731067a03dcf5…
2025-08-23 18:47 UTC2025-08N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-076a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-07fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-07b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-0703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-072680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-075bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-07d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-07d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-0779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-07301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-071e350fbaab3a…
2024-05-31 18:47 UTC2024-05N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-078072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-075c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-075d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-074b0b4de00fa7…
2022-03-09 01:35 UTC2022-03N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-07bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-07782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-0787673890dc5c…
2021-03-12 10:30 UTC2021-03N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-075aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-078869cabd3fbd…
2020-11-12 02:37 UTC2020-11N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-07c0c555d07b60…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-076a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-071c564ffb4f44…
2023-12-20 04:57 UTC2023-12N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-07ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-07a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-079b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-07a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-073f0d92c62455…
2023-05-13 08:27 UTC2023-05N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-07053a50430f4f…
2023-01-26 05:58 UTC2023-01N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-073bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-073a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-07f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-07e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-07cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N213535-001EVRYSDI0.75MG/MLFOR SOLUTION / ORALRLD, RS2020-08-07a50c72e98297…

Observed Orange Book patent history#

Patent history page 1 of 4 · 141 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N213535-00195869552033-02-08Drug substance, Drug product2020-09-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213535-00199697542035-05-11U-1943Drug substance, Drug product2020-09-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213535-001118276462036-01-25U-19432023-12-14011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213535-001119381362036-11-08Drug product2024-04-17011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213535-001123502732038-10-01U-19432025-07-31011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213535-001115344442038-10-04U-19432023-01-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213535-001121227892041-04-15Drug substance, Drug product2024-11-12011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213535-00195869552033-02-08Drug substance, Drug product2020-09-0331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213535-00199697542035-05-11U-1943Drug substance, Drug product2020-09-0331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213535-001118276462036-01-25U-19432023-12-1431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213535-001119381362036-11-08Drug product2024-04-1731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213535-001123502732038-10-01U-19432025-07-3131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213535-001115344442038-10-04U-19432023-01-2531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213535-001121227892041-04-15Drug substance, Drug product2024-11-1231067a03dcf5…
2025-08-23 18:47 UTC2025-08N213535-00195869552033-02-08Drug substance, Drug product2020-09-036a471c1ec25d…
2025-08-23 18:47 UTC2025-08N213535-00199697542035-05-11U-1943Drug substance, Drug product2020-09-036a471c1ec25d…
2025-08-23 18:47 UTC2025-08N213535-001118276462036-01-25U-19432023-12-146a471c1ec25d…
2025-08-23 18:47 UTC2025-08N213535-001119381362036-11-08Drug product2024-04-176a471c1ec25d…
2025-08-23 18:47 UTC2025-08N213535-001123502732038-10-01U-19432025-07-316a471c1ec25d…
2025-08-23 18:47 UTC2025-08N213535-001115344442038-10-04U-19432023-01-256a471c1ec25d…
2025-08-23 18:47 UTC2025-08N213535-001121227892041-04-15Drug substance, Drug product2024-11-126a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N213535-00195869552033-02-08Drug substance, Drug product2020-09-03fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N213535-00199697542035-05-11U-1943Drug substance, Drug product2020-09-03fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N213535-001118276462036-01-25U-19432023-12-14fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N213535-001119381362036-11-08Drug product2024-04-17fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N213535-001115344442038-10-04U-19432023-01-25fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N213535-001121227892041-04-15Drug substance, Drug product2024-11-12fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N213535-00195869552033-02-08Drug substance, Drug product2020-09-03b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N213535-00199697542035-05-11U-1943Drug substance, Drug product2020-09-03b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N213535-001118276462036-01-25U-19432023-12-14b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N213535-001119381362036-11-08Drug product2024-04-17b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N213535-001115344442038-10-04U-19432023-01-25b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N213535-001121227892041-04-15Drug substance, Drug product2024-11-12b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N213535-00195869552033-02-08Drug substance, Drug product2020-09-0303ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N213535-00199697542035-05-11U-1943Drug substance, Drug product2020-09-0303ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N213535-001118276462036-01-25U-19432023-12-1403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N213535-001119381362036-11-08Drug product2024-04-1703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N213535-001115344442038-10-04U-19432023-01-2503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N213535-001121227892041-04-15Drug substance, Drug product2024-11-1203ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N213535-00195869552033-02-08Drug substance, Drug product2020-09-032680178bc6a6…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 4 · 136 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-02-19 14:30 UTC2026-02N213535-001M-2702026-10-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213535-001ODE-3342027-08-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213535-001ODE-4002029-05-27011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213535-001NPP2025-05-2731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213535-001NCE2025-08-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213535-001M-2702026-10-0331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213535-001ODE-3342027-08-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213535-001ODE-4002029-05-2731067a03dcf5…
2025-08-23 18:47 UTC2025-08N213535-001NPP2025-05-276a471c1ec25d…
2025-08-23 18:47 UTC2025-08N213535-001NCE2025-08-076a471c1ec25d…
2025-08-23 18:47 UTC2025-08N213535-001M-2702026-10-036a471c1ec25d…
2025-08-23 18:47 UTC2025-08N213535-001ODE-3342027-08-076a471c1ec25d…
2025-08-23 18:47 UTC2025-08N213535-001ODE-4002029-05-276a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N213535-001NPP2025-05-27fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N213535-001NCE2025-08-07fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N213535-001M-2702026-10-03fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N213535-001ODE-3342027-08-07fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N213535-001ODE-4002029-05-27fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N213535-001NPP2025-05-27b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N213535-001NCE2025-08-07b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N213535-001M-2702026-10-03b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N213535-001ODE-3342027-08-07b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N213535-001ODE-4002029-05-27b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N213535-001NPP2025-05-2703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N213535-001NCE2025-08-0703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N213535-001M-2702026-10-0303ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N213535-001ODE-3342027-08-0703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N213535-001ODE-4002029-05-2703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N213535-001NPP2025-05-272680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N213535-001NCE2025-08-072680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N213535-001M-2702026-10-032680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N213535-001ODE-3342027-08-072680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N213535-001ODE-4002029-05-272680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N213535-001NPP2025-05-275bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N213535-001NCE2025-08-075bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N213535-001M-2702026-10-035bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N213535-001ODE-3342027-08-075bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N213535-001ODE-4002029-05-275bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N213535-001NPP2025-05-27d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N213535-001NCE2025-08-07d8e5a09893c0…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
EVRYSDIRISDIPLAMGenentech, Inc.eceb9a99-7191-4be5-87c3-0102707cf98e2026-02-19Adverse reactionsExact identifier
application applno (NDA): 213535
application number: NDA213535
ndc (product): 50242-175

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 8 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
50242-175EVRYSDIRisdiplamGenentech Inc.NDACurrent
50242-175EVRYSDIRisdiplamGenentech Inc.NDACurrent
50242-175EVRYSDIRisdiplamGenentech Inc.NDACurrent
50242-175EVRYSDIRisdiplamGenentech Inc.NDACurrent
50242-175EVRYSDIRisdiplamGenentech Inc.NDACurrent
50242-175EVRYSDIRisdiplamGenentech Inc.NDACurrent
50242-175EVRYSDIRisdiplamGenentech Inc.NDACurrent
50242-175EVRYSDIRisdiplamGenentech Inc.NDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
85090SUPPL 2026-02-20
85089SUPPL 2026-02-20
84841SUPPL 2026-01-27
84821SUPPL 2026-01-22
81248SUPPL 2025-02-14
81229SUPPL 2025-02-12
79658SUPPL 2024-09-19
79649SUPPL 2024-09-18
77684SUPPL 2024-03-01
77679SUPPL 2024-03-01
75674SUPPL 2023-10-05
73877SUPPL 2023-03-27
73871SUPPL 2023-03-27
72151SUPPL2022-09-23
72138SUPPL2022-09-22
71196SUPPL2022-06-01
71195SUPPL2022-06-01
71175SUPPL2022-05-31
71174SUPPL2022-05-31
67406SUPPL2021-05-05
67396SUPPL2021-05-04
64492ORIG2020-09-04
64248ORIG2020-08-10
64246ORIG2020-08-03