Application 213674

Type
NDA
Sponsor
ASTELLAS

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001XTANDIENZALUTAMIDETABLET, FILM COATED40MGYesNo
002XTANDIENZALUTAMIDETABLET, FILM COATED80MGYesNo

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N213674-001XTANDIENZALUTAMIDE40MGTABLET / ORALABRLD2020-08-04
N213674-002XTANDIENZALUTAMIDE80MGTABLET / ORALABRLD, RS2020-08-04

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
N213674-001AB
N213674-002AB

Orange Book patents#

Current patent rows page 1 of 1 · 33 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N213674-00191269412026-05-15U-23452020-09-03
N213674-00191269412026-05-15U-27082020-09-03
N213674-00191269412026-05-15U-37632020-09-03
N213674-00181832742026-08-24U-23452020-09-03
N213674-00181832742026-08-24U-27082020-09-03
N213674-00181832742026-08-24U-37632020-09-03
N213674-00177095172027-08-13Drug substance, Drug product2020-09-03
N213674-001118396892033-09-11Drug product2023-12-19
N213674-001125023572033-09-11U-43632026-01-07
N213674-001125023572033-09-11U-43642026-01-07
N213674-001125023572033-09-11U-43652026-01-07
N213674-001121616282037-02-23U-41012025-01-08
N213674-001121616282037-02-23U-41022025-01-08
N213674-001121616282037-02-23U-41032025-01-08
N213674-001121616282037-02-23U-41042025-01-08
N213674-00291269412026-05-15U-23452020-09-03
N213674-00291269412026-05-15U-27082020-09-03
N213674-00291269412026-05-15U-37632020-09-03
N213674-00281832742026-08-24U-23452020-09-03
N213674-00281832742026-08-24U-27082020-09-03
N213674-00281832742026-08-24U-37632020-09-03
N213674-00277095172027-08-13Drug substance, Drug product2020-09-03
N213674-002118396892033-09-11Drug product2023-12-19
N213674-002124471282033-09-11U-43122025-11-17
N213674-002124471282033-09-11U-43132025-11-17
N213674-002124471282033-09-11U-43142025-11-17
N213674-002125023572033-09-11U-43632026-01-07
N213674-002125023572033-09-11U-43642026-01-07
N213674-002125023572033-09-11U-43652026-01-07
N213674-002121616282037-02-23U-41012025-01-08
N213674-002121616282037-02-23U-41022025-01-08
N213674-002121616282037-02-23U-41032025-01-08
N213674-002121616282037-02-23U-41042025-01-08

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 2 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N213674-001I-9262026-11-17
N213674-002I-9262026-11-17

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 74 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N213674-001XTANDI40MGTABLET / ORALRLD2020-08-04011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-002XTANDI80MGTABLET / ORALRLD, RS2020-08-04011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213674-001XTANDI40MGTABLET / ORALRLD2020-08-0431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213674-002XTANDI80MGTABLET / ORALRLD, RS2020-08-0431067a03dcf5…
2025-08-23 18:47 UTC2025-08N213674-001XTANDI40MGTABLET / ORALRLD2020-08-046a471c1ec25d…
2025-08-23 18:47 UTC2025-08N213674-002XTANDI80MGTABLET / ORALRLD, RS2020-08-046a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N213674-001XTANDI40MGTABLET / ORALRLD2020-08-04fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N213674-002XTANDI80MGTABLET / ORALRLD, RS2020-08-04fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N213674-001XTANDI40MGTABLET / ORALRLD2020-08-04b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N213674-002XTANDI80MGTABLET / ORALRLD, RS2020-08-04b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N213674-001XTANDI40MGTABLET / ORALRLD2020-08-0403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N213674-002XTANDI80MGTABLET / ORALRLD, RS2020-08-0403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N213674-001XTANDI40MGTABLET / ORALRLD2020-08-042680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N213674-002XTANDI80MGTABLET / ORALRLD, RS2020-08-042680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N213674-001XTANDI40MGTABLET / ORALRLD2020-08-045bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N213674-002XTANDI80MGTABLET / ORALRLD, RS2020-08-045bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N213674-001XTANDI40MGTABLET / ORALRLD2020-08-04d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N213674-002XTANDI80MGTABLET / ORALRLD, RS2020-08-04d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N213674-001XTANDI40MGTABLET / ORALRLD2020-08-04d06236e962d9…
2024-10-29 15:01 UTC2024-10N213674-002XTANDI80MGTABLET / ORALRLD, RS2020-08-04d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N213674-001XTANDI40MGTABLET / ORALRLD2020-08-0479d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N213674-002XTANDI80MGTABLET / ORALRLD, RS2020-08-0479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N213674-001XTANDI40MGTABLET / ORALRLD2020-08-04301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N213674-002XTANDI80MGTABLET / ORALRLD, RS2020-08-04301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N213674-001XTANDI40MGTABLET / ORALRLD2020-08-041e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N213674-002XTANDI80MGTABLET / ORALRLD, RS2020-08-041e350fbaab3a…
2024-05-31 18:47 UTC2024-05N213674-001XTANDI40MGTABLET / ORALRLD2020-08-048072bd15b7f6…
2024-05-31 18:47 UTC2024-05N213674-002XTANDI80MGTABLET / ORALRLD, RS2020-08-048072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N213674-001XTANDI40MGTABLET / ORALRLD2020-08-045c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N213674-002XTANDI80MGTABLET / ORALRLD, RS2020-08-045c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N213674-001XTANDI40MGTABLET / ORALRLD2020-08-045d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N213674-002XTANDI80MGTABLET / ORALRLD, RS2020-08-045d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N213674-001XTANDI40MGTABLET / ORALRLD2020-08-044b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N213674-002XTANDI80MGTABLET / ORALRLD, RS2020-08-044b0b4de00fa7…
2022-03-09 01:35 UTC2022-03N213674-001XTANDI40MGTABLET / ORALRLD2020-08-04bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N213674-002XTANDI80MGTABLET / ORALRLD, RS2020-08-04bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N213674-001XTANDI40MGTABLET / ORALRLD2020-08-04782e0a99824c…
2021-12-28 21:50 UTC2021-12N213674-002XTANDI80MGTABLET / ORALRLD, RS2020-08-04782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N213674-001XTANDI40MGTABLET / ORALRLD2020-08-0487673890dc5c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N213674-002XTANDI80MGTABLET / ORALRLD, RS2020-08-0487673890dc5c…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N213674-001AB1a50c72e98297…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N213674-002AB1a50c72e98297…

Observed Orange Book patent history#

Patent history page 1 of 14 · 541 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N213674-00191269412026-05-15U-27082020-09-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-00191269412026-05-15U-23452020-09-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-00191269412026-05-15U-37632020-09-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-00181832742026-08-24U-23452020-09-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-00181832742026-08-24U-27082020-09-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-00181832742026-08-24U-37632020-09-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-00177095172027-08-13Drug substance, Drug product2020-09-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-001118396892033-09-11Drug product2023-12-19011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-001125023572033-09-11U-43632026-01-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-001125023572033-09-11U-43642026-01-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-001125023572033-09-11U-43652026-01-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-001121616282037-02-23U-41012025-01-08011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-001121616282037-02-23U-41022025-01-08011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-001121616282037-02-23U-41032025-01-08011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-001121616282037-02-23U-41042025-01-08011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-00291269412026-05-15U-27082020-09-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-00291269412026-05-15U-23452020-09-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-00291269412026-05-15U-37632020-09-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-00281832742026-08-24U-27082020-09-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-00281832742026-08-24U-23452020-09-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-00281832742026-08-24U-37632020-09-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-00277095172027-08-13Drug substance, Drug product2020-09-03011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-002118396892033-09-11Drug product2023-12-19011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-002124471282033-09-11U-43122025-11-17011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-002124471282033-09-11U-43132025-11-17011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-002124471282033-09-11U-43142025-11-17011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-002125023572033-09-11U-43632026-01-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-002125023572033-09-11U-43642026-01-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-002125023572033-09-11U-43652026-01-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-002121616282037-02-23U-41022025-01-08011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-002121616282037-02-23U-41032025-01-08011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-002121616282037-02-23U-41042025-01-08011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-002121616282037-02-23U-41012025-01-08011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213674-00191269412026-05-15U-27082020-09-0331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213674-00191269412026-05-15U-23452020-09-0331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213674-00191269412026-05-15U-37632020-09-0331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213674-00181832742026-08-24U-23452020-09-0331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213674-00181832742026-08-24U-27082020-09-0331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213674-00181832742026-08-24U-37632020-09-0331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213674-00177095172027-08-13Drug substance, Drug product2020-09-0331067a03dcf5…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 2 · 68 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-02-19 14:30 UTC2026-02N213674-001I-9262026-11-17011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213674-002I-9262026-11-17011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213674-001I-9262026-11-1731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213674-002I-9262026-11-1731067a03dcf5…
2025-08-23 18:47 UTC2025-08N213674-001I-9262026-11-176a471c1ec25d…
2025-08-23 18:47 UTC2025-08N213674-002I-9262026-11-176a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N213674-001I-9262026-11-17fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N213674-002I-9262026-11-17fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N213674-001I-9262026-11-17b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N213674-002I-9262026-11-17b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N213674-001I-9262026-11-1703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N213674-002I-9262026-11-1703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N213674-001I-9262026-11-172680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N213674-002I-9262026-11-172680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N213674-001I-9262026-11-175bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N213674-002I-9262026-11-175bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N213674-001I-9262026-11-17d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N213674-002I-9262026-11-17d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N213674-001I-9262026-11-17d06236e962d9…
2024-10-29 15:01 UTC2024-10N213674-002I-9262026-11-17d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N213674-001I-9262026-11-1779d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N213674-002I-9262026-11-1779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N213674-001I-9262026-11-17301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N213674-002I-9262026-11-17301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N213674-001I-9262026-11-171e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N213674-002I-9262026-11-171e350fbaab3a…
2024-05-31 18:47 UTC2024-05N213674-001I-9262026-11-178072bd15b7f6…
2024-05-31 18:47 UTC2024-05N213674-002I-9262026-11-178072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N213674-001I-8082022-12-165c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N213674-002I-8082022-12-165c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N213674-001I-8082022-12-165d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N213674-002I-8082022-12-165d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N213674-001I-8082022-12-164b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N213674-002I-8082022-12-164b0b4de00fa7…
2022-03-09 01:35 UTC2022-03N213674-001I-8082022-12-16bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N213674-002I-8082022-12-16bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N213674-001I-7862021-07-13782e0a99824c…
2021-12-28 21:50 UTC2021-12N213674-001I-8082022-12-16782e0a99824c…
2021-12-28 21:50 UTC2021-12N213674-002I-7862021-07-13782e0a99824c…
2021-12-28 21:50 UTC2021-12N213674-002I-8082022-12-16782e0a99824c…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
XtandiENZALUTAMIDEAstellas Pharma US, Inc.b129fdc9-1d8e-425c-a5a9-8a2ed36dfbdf2026-05-26Warnings, Adverse reactionsExact identifier
application applno (NDA): 213674
application number: NDA213674
ndc (product): 0469-1725
ndc (product): 0469-0625
ndc (product): 0469-0725

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 14 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
0469-0625XtandienzalutamideAstellas Pharma US, Inc.NDACurrent
0469-0625XtandienzalutamideAstellas Pharma US, Inc.NDACurrent
0469-0625XtandienzalutamideAstellas Pharma US, Inc.NDACurrent
0469-0625XtandienzalutamideAstellas Pharma US, Inc.NDACurrent
0469-0625XtandienzalutamideAstellas Pharma US, Inc.NDACurrent
0469-0625XtandienzalutamideAstellas Pharma US, Inc.NDACurrent
0469-0725XtandienzalutamideAstellas Pharma US, Inc.NDACurrent
0469-0725XtandienzalutamideAstellas Pharma US, Inc.NDACurrent
0469-0725XtandienzalutamideAstellas Pharma US, Inc.NDACurrent
0469-0725XtandienzalutamideAstellas Pharma US, Inc.NDACurrent
0469-0725XtandienzalutamideAstellas Pharma US, Inc.NDACurrent
0469-0725XtandienzalutamideAstellas Pharma US, Inc.NDACurrent
0469-1725XtandienzalutamideAstellas Pharma US, Inc.NDACurrent
0469-1725XtandienzalutamideAstellas Pharma US, Inc.NDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
84454SUPPL 2025-12-18
84397SUPPL 2025-12-12
81710SUPPL 2025-03-25
81706SUPPL 2025-03-24
80924SUPPL 2025-02-12
81146SUPPL 2025-02-07
76627SUPPL 2023-11-17
76592SUPPL 2023-11-17
72073SUPPL2022-09-13
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