Application 214662

Type
NDA
Sponsor
MIRUM PHARMA INC

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001LIVMARLIMARALIXIBAT CHLORIDESOLUTION;ORAL9.5MGNoNo
002LIVMARLIMARALIXIBAT CHLORIDESOLUTION;ORALEQ 19MG BASE/MLYesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N214662-001LIVMARLIMARALIXIBAT CHLORIDEEQ 9.5MG BASE/MLSOLUTION / ORALRLD, RS2021-09-29
N214662-002LIVMARLIMARALIXIBAT CHLORIDEEQ 19MG BASE/MLSOLUTION / ORALRLD, RS2024-07-24

Orange Book patents#

Current patent rows page 1 of 1 · 17 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N214662-001112600532031-05-26U-32902022-03-01
N214662-001112600532031-05-26U-39742022-03-01
N214662-001105126572032-10-26U-38502024-03-22
N214662-001112296612032-10-26U-38502024-03-22
N214662-001113762512032-10-26U-32902022-07-19
N214662-001113762512032-10-26U-39742022-07-19
N214662-001112296472040-02-12U-32902022-02-01
N214662-001112296472040-02-12U-39742022-02-01
N214662-001114977452040-02-12U-32902022-11-30
N214662-001114977452040-02-12U-39742022-11-30
N214662-001119185782040-02-12U-32902024-03-22
N214662-001119185782040-02-12U-39742024-03-22
N214662-001125996022040-02-12U-32902026-04-22
N214662-001125996022040-02-12U-39742026-04-22
N214662-002105126572032-10-26U-39732024-08-23
N214662-002112296612032-10-26U-39732024-08-23
N214662-002123502672032-10-26U-39732025-08-05

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 11 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N214662-001NPP2026-03-13
N214662-001NCE2026-09-29
N214662-001I-9382027-03-13
N214662-001ODE-3792028-09-29
N214662-001ODE-4292030-03-13
N214662-001ODE-4712031-03-13
N214662-002NCE2026-09-29
N214662-002ODE*2028-09-29
N214662-002ODE*2030-03-13
N214662-002ODE*2031-03-13
N214662-002ODE-4902031-07-24

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-01 22:54:322026-06N214662-001LIVMARLIEQ 9.5MG BASE/MLSOLUTION / ORALRLD, RS2021-09-29a50c72e98297…
2026-08-01 22:54:322026-06N214662-002LIVMARLIEQ 19MG BASE/MLSOLUTION / ORALRLD, RS2024-07-24a50c72e98297…

Observed Orange Book patent history#

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-08-01 22:54:322026-06N214662-001112600532031-05-26U-39742022-03-01a50c72e98297…
2026-08-01 22:54:322026-06N214662-001112600532031-05-26U-32902022-03-01a50c72e98297…
2026-08-01 22:54:322026-06N214662-001105126572032-10-26U-38502024-03-22a50c72e98297…
2026-08-01 22:54:322026-06N214662-001112296612032-10-26U-38502024-03-22a50c72e98297…
2026-08-01 22:54:322026-06N214662-001113762512032-10-26U-32902022-07-19a50c72e98297…
2026-08-01 22:54:322026-06N214662-001113762512032-10-26U-39742022-07-19a50c72e98297…
2026-08-01 22:54:322026-06N214662-001112296472040-02-12U-39742022-02-01a50c72e98297…
2026-08-01 22:54:322026-06N214662-001112296472040-02-12U-32902022-02-01a50c72e98297…
2026-08-01 22:54:322026-06N214662-001114977452040-02-12U-39742022-11-30a50c72e98297…
2026-08-01 22:54:322026-06N214662-001114977452040-02-12U-32902022-11-30a50c72e98297…
2026-08-01 22:54:322026-06N214662-001119185782040-02-12U-32902024-03-22a50c72e98297…
2026-08-01 22:54:322026-06N214662-001119185782040-02-12U-39742024-03-22a50c72e98297…
2026-08-01 22:54:322026-06N214662-001125996022040-02-12U-39742026-04-22a50c72e98297…
2026-08-01 22:54:322026-06N214662-001125996022040-02-12U-32902026-04-22a50c72e98297…
2026-08-01 22:54:322026-06N214662-002105126572032-10-26U-39732024-08-23a50c72e98297…
2026-08-01 22:54:322026-06N214662-002112296612032-10-26U-39732024-08-23a50c72e98297…
2026-08-01 22:54:322026-06N214662-002123502672032-10-26U-39732025-08-05a50c72e98297…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-08-01 22:54:322026-06N214662-001NPP2026-03-13a50c72e98297…
2026-08-01 22:54:322026-06N214662-001NCE2026-09-29a50c72e98297…
2026-08-01 22:54:322026-06N214662-001I-9382027-03-13a50c72e98297…
2026-08-01 22:54:322026-06N214662-001ODE-3792028-09-29a50c72e98297…
2026-08-01 22:54:322026-06N214662-001ODE-4292030-03-13a50c72e98297…
2026-08-01 22:54:322026-06N214662-001ODE-4712031-03-13a50c72e98297…
2026-08-01 22:54:322026-06N214662-002NCE2026-09-29a50c72e98297…
2026-08-01 22:54:322026-06N214662-002ODE*2028-09-29a50c72e98297…
2026-08-01 22:54:322026-06N214662-002ODE*2030-03-13a50c72e98297…
2026-08-01 22:54:322026-06N214662-002ODE*2031-03-13a50c72e98297…
2026-08-01 22:54:322026-06N214662-002ODE-4902031-07-24a50c72e98297…

openFDA label cross-check#

Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report. Every label matching the complete exact-identifier union is deduplicated and paginated below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
LivmarliMARALIXIBAT CHLORIDEMirum Pharmaceuticals Inc.64000394-1ef6-4e76-8ba8-11f25ba1b1672025-04-10Warnings, Adverse reactionsExact identifier
application applno (NDA): 214662
application number: NDA214662
ndc (product): 79378-110

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 3 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
79378-110Livmarlimaralixibat chlorideMirum Pharmaceuticals Inc.NDACurrent
79378-110Livmarlimaralixibat chlorideMirum Pharmaceuticals Inc.NDACurrent
79378-110Livmarlimaralixibat chlorideMirum Pharmaceuticals Inc.NDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
79234SUPPL 2026-04-15
79233SUPPL 2026-04-15
80198SUPPL 2024-11-12
80189SUPPL 2024-11-12
79210SUPPL 2024-07-25
79209SUPPL 2024-07-25
77834SUPPL 2024-03-14
77833SUPPL 2024-03-14
77830SUPPL 2024-03-14
77829SUPPL 2024-03-14
73758SUPPL 2023-03-14
73742SUPPL 2023-03-14
70704SUPPL2022-04-05
70684SUPPL2022-04-04
69524ORIG2021-12-10
69046ORIG2021-10-21
68811ORIG2021-09-30
68809ORIG2021-09-29