Application 214998

Type
NDA
Sponsor
MYOKARDIA INC

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001CAMZYOSMAVACAMTENCAPSULE; ORAL2.5MGNoNo
002CAMZYOSMAVACAMTENCAPSULE; ORAL5MGNoNo
003CAMZYOSMAVACAMTENCAPSULE; ORAL10MGNoNo
004CAMZYOSMAVACAMTENCAPSULE; ORAL15MGNoNo

Source provenance: Browse the complete Orange Book source catalog · source snapshot 43.

Orange Book products#

Current product rows page 1 of 1 · 4 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N214998-001CAMZYOSMAVACAMTEN2.5MGCAPSULE / ORALRLD2022-04-28
N214998-002CAMZYOSMAVACAMTEN5MGCAPSULE / ORALRLD, RS2022-04-28
N214998-003CAMZYOSMAVACAMTEN10MGCAPSULE / ORALRLD2022-04-28
N214998-004CAMZYOSMAVACAMTEN15MGCAPSULE / ORALRLD2022-04-28

Orange Book patents#

Current patent rows page 1 of 1 · 8 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N214998-00195858832034-06-19U-33732022-05-26
N214998-001RE500502036-04-28Drug substance, Drug product2024-08-20
N214998-00295858832034-06-19U-33732022-05-26
N214998-002RE500502036-04-28Drug substance, Drug product2024-08-20
N214998-00395858832034-06-19U-33732022-05-26
N214998-003RE500502036-04-28Drug substance, Drug product2024-08-20
N214998-00495858832034-06-19U-33732022-05-26
N214998-004RE500502036-04-28Drug substance, Drug product2024-08-20

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 12 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N214998-001M-2972026-06-15
N214998-001NCE2027-04-28
N214998-001ODE-3982029-04-28
N214998-002M-2972026-06-15
N214998-002NCE2027-04-28
N214998-002ODE-3982029-04-28
N214998-003M-2972026-06-15
N214998-003NCE2027-04-28
N214998-003ODE-3982029-04-28
N214998-004M-2972026-06-15
N214998-004NCE2027-04-28
N214998-004ODE-3982029-04-28

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 124 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-09-14 22:38:342026-08N214998-001CAMZYOS2.5MGCAPSULE / ORALRLD2022-04-2884e616aacf4f…
2026-09-14 22:38:342026-08N214998-002CAMZYOS5MGCAPSULE / ORALRLD, RS2022-04-2884e616aacf4f…
2026-09-14 22:38:342026-08N214998-003CAMZYOS10MGCAPSULE / ORALRLD2022-04-2884e616aacf4f…
2026-09-14 22:38:342026-08N214998-004CAMZYOS15MGCAPSULE / ORALRLD2022-04-2884e616aacf4f…
2026-08-18 06:07:402026-07N214998-001CAMZYOS2.5MGCAPSULE / ORALRLD2022-04-28caaa826d4ba7…
2026-08-18 06:07:402026-07N214998-002CAMZYOS5MGCAPSULE / ORALRLD, RS2022-04-28caaa826d4ba7…
2026-08-18 06:07:402026-07N214998-003CAMZYOS10MGCAPSULE / ORALRLD2022-04-28caaa826d4ba7…
2026-08-18 06:07:402026-07N214998-004CAMZYOS15MGCAPSULE / ORALRLD2022-04-28caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N214998-001CAMZYOS2.5MGCAPSULE / ORALRLD2022-04-28011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214998-002CAMZYOS5MGCAPSULE / ORALRLD, RS2022-04-28011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214998-003CAMZYOS10MGCAPSULE / ORALRLD2022-04-28011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214998-004CAMZYOS15MGCAPSULE / ORALRLD2022-04-28011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214998-001CAMZYOS2.5MGCAPSULE / ORALRLD2022-04-2831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214998-002CAMZYOS5MGCAPSULE / ORALRLD, RS2022-04-2831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214998-003CAMZYOS10MGCAPSULE / ORALRLD2022-04-2831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214998-004CAMZYOS15MGCAPSULE / ORALRLD2022-04-2831067a03dcf5…
2025-08-23 18:47 UTC2025-08N214998-001CAMZYOS2.5MGCAPSULE / ORALRLD2022-04-286a471c1ec25d…
2025-08-23 18:47 UTC2025-08N214998-002CAMZYOS5MGCAPSULE / ORALRLD, RS2022-04-286a471c1ec25d…
2025-08-23 18:47 UTC2025-08N214998-003CAMZYOS10MGCAPSULE / ORALRLD2022-04-286a471c1ec25d…
2025-08-23 18:47 UTC2025-08N214998-004CAMZYOS15MGCAPSULE / ORALRLD2022-04-286a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N214998-001CAMZYOS2.5MGCAPSULE / ORALRLD2022-04-28fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N214998-002CAMZYOS5MGCAPSULE / ORALRLD, RS2022-04-28fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N214998-003CAMZYOS10MGCAPSULE / ORALRLD2022-04-28fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N214998-004CAMZYOS15MGCAPSULE / ORALRLD2022-04-28fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N214998-001CAMZYOS2.5MGCAPSULE / ORALRLD2022-04-28b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N214998-002CAMZYOS5MGCAPSULE / ORALRLD, RS2022-04-28b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N214998-003CAMZYOS10MGCAPSULE / ORALRLD2022-04-28b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N214998-004CAMZYOS15MGCAPSULE / ORALRLD2022-04-28b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N214998-001CAMZYOS2.5MGCAPSULE / ORALRLD2022-04-2803ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N214998-002CAMZYOS5MGCAPSULE / ORALRLD, RS2022-04-2803ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N214998-003CAMZYOS10MGCAPSULE / ORALRLD2022-04-2803ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N214998-004CAMZYOS15MGCAPSULE / ORALRLD2022-04-2803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N214998-001CAMZYOS2.5MGCAPSULE / ORALRLD2022-04-282680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N214998-002CAMZYOS5MGCAPSULE / ORALRLD, RS2022-04-282680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N214998-003CAMZYOS10MGCAPSULE / ORALRLD2022-04-282680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N214998-004CAMZYOS15MGCAPSULE / ORALRLD2022-04-282680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N214998-001CAMZYOS2.5MGCAPSULE / ORALRLD2022-04-285bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N214998-002CAMZYOS5MGCAPSULE / ORALRLD, RS2022-04-285bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N214998-003CAMZYOS10MGCAPSULE / ORALRLD2022-04-285bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N214998-004CAMZYOS15MGCAPSULE / ORALRLD2022-04-285bbf6a4d5a75…

Observed Orange Book patent history#

Patent history page 1 of 7 · 248 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-09-14 22:38:342026-08N214998-00195858832034-06-19U-33732022-05-2684e616aacf4f…
2026-09-14 22:38:342026-08N214998-001RE500502036-04-28Drug substance, Drug product2024-08-2084e616aacf4f…
2026-09-14 22:38:342026-08N214998-00295858832034-06-19U-33732022-05-2684e616aacf4f…
2026-09-14 22:38:342026-08N214998-002RE500502036-04-28Drug substance, Drug product2024-08-2084e616aacf4f…
2026-09-14 22:38:342026-08N214998-00395858832034-06-19U-33732022-05-2684e616aacf4f…
2026-09-14 22:38:342026-08N214998-003RE500502036-04-28Drug substance, Drug product2024-08-2084e616aacf4f…
2026-09-14 22:38:342026-08N214998-00495858832034-06-19U-33732022-05-2684e616aacf4f…
2026-09-14 22:38:342026-08N214998-004RE500502036-04-28Drug substance, Drug product2024-08-2084e616aacf4f…
2026-08-18 06:07:402026-07N214998-00195858832034-06-19U-33732022-05-26caaa826d4ba7…
2026-08-18 06:07:402026-07N214998-001RE500502036-04-28Drug substance, Drug product2024-08-20caaa826d4ba7…
2026-08-18 06:07:402026-07N214998-00295858832034-06-19U-33732022-05-26caaa826d4ba7…
2026-08-18 06:07:402026-07N214998-002RE500502036-04-28Drug substance, Drug product2024-08-20caaa826d4ba7…
2026-08-18 06:07:402026-07N214998-00395858832034-06-19U-33732022-05-26caaa826d4ba7…
2026-08-18 06:07:402026-07N214998-003RE500502036-04-28Drug substance, Drug product2024-08-20caaa826d4ba7…
2026-08-18 06:07:402026-07N214998-00495858832034-06-19U-33732022-05-26caaa826d4ba7…
2026-08-18 06:07:402026-07N214998-004RE500502036-04-28Drug substance, Drug product2024-08-20caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N214998-00195858832034-06-19U-33732022-05-26011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214998-001RE500502036-04-28Drug substance, Drug product2024-08-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214998-00295858832034-06-19U-33732022-05-26011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214998-002RE500502036-04-28Drug substance, Drug product2024-08-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214998-00395858832034-06-19U-33732022-05-26011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214998-003RE500502036-04-28Drug substance, Drug product2024-08-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214998-00495858832034-06-19U-33732022-05-26011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214998-004RE500502036-04-28Drug substance, Drug product2024-08-20011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214998-00195858832034-06-19U-33732022-05-2631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214998-001RE500502036-04-28Drug substance, Drug product2024-08-2031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214998-00295858832034-06-19U-33732022-05-2631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214998-002RE500502036-04-28Drug substance, Drug product2024-08-2031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214998-00395858832034-06-19U-33732022-05-2631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214998-003RE500502036-04-28Drug substance, Drug product2024-08-2031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214998-00495858832034-06-19U-33732022-05-2631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214998-004RE500502036-04-28Drug substance, Drug product2024-08-2031067a03dcf5…
2025-08-23 18:47 UTC2025-08N214998-00195858832034-06-19U-33732022-05-266a471c1ec25d…
2025-08-23 18:47 UTC2025-08N214998-001RE500502034-06-19Drug substance, Drug product2024-08-206a471c1ec25d…
2025-08-23 18:47 UTC2025-08N214998-00295858832034-06-19U-33732022-05-266a471c1ec25d…
2025-08-23 18:47 UTC2025-08N214998-002RE500502034-06-19Drug substance, Drug product2024-08-206a471c1ec25d…
2025-08-23 18:47 UTC2025-08N214998-00395858832034-06-19U-33732022-05-266a471c1ec25d…
2025-08-23 18:47 UTC2025-08N214998-003RE500502034-06-19Drug substance, Drug product2024-08-206a471c1ec25d…
2025-08-23 18:47 UTC2025-08N214998-00495858832034-06-19U-33732022-05-266a471c1ec25d…
2025-08-23 18:47 UTC2025-08N214998-004RE500502034-06-19Drug substance, Drug product2024-08-206a471c1ec25d…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 8 · 312 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-09-14 22:38:342026-08N214998-001M-2972026-06-1584e616aacf4f…
2026-09-14 22:38:342026-08N214998-001NCE2027-04-2884e616aacf4f…
2026-09-14 22:38:342026-08N214998-001ODE-3982029-04-2884e616aacf4f…
2026-09-14 22:38:342026-08N214998-002M-2972026-06-1584e616aacf4f…
2026-09-14 22:38:342026-08N214998-002NCE2027-04-2884e616aacf4f…
2026-09-14 22:38:342026-08N214998-002ODE-3982029-04-2884e616aacf4f…
2026-09-14 22:38:342026-08N214998-003M-2972026-06-1584e616aacf4f…
2026-09-14 22:38:342026-08N214998-003NCE2027-04-2884e616aacf4f…
2026-09-14 22:38:342026-08N214998-003ODE-3982029-04-2884e616aacf4f…
2026-09-14 22:38:342026-08N214998-004M-2972026-06-1584e616aacf4f…
2026-09-14 22:38:342026-08N214998-004NCE2027-04-2884e616aacf4f…
2026-09-14 22:38:342026-08N214998-004ODE-3982029-04-2884e616aacf4f…
2026-08-18 06:07:402026-07N214998-001M-2972026-06-15caaa826d4ba7…
2026-08-18 06:07:402026-07N214998-001NCE2027-04-28caaa826d4ba7…
2026-08-18 06:07:402026-07N214998-001ODE-3982029-04-28caaa826d4ba7…
2026-08-18 06:07:402026-07N214998-002M-2972026-06-15caaa826d4ba7…
2026-08-18 06:07:402026-07N214998-002NCE2027-04-28caaa826d4ba7…
2026-08-18 06:07:402026-07N214998-002ODE-3982029-04-28caaa826d4ba7…
2026-08-18 06:07:402026-07N214998-003M-2972026-06-15caaa826d4ba7…
2026-08-18 06:07:402026-07N214998-003NCE2027-04-28caaa826d4ba7…
2026-08-18 06:07:402026-07N214998-003ODE-3982029-04-28caaa826d4ba7…
2026-08-18 06:07:402026-07N214998-004M-2972026-06-15caaa826d4ba7…
2026-08-18 06:07:402026-07N214998-004NCE2027-04-28caaa826d4ba7…
2026-08-18 06:07:402026-07N214998-004ODE-3982029-04-28caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N214998-001M-2972026-06-15011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214998-001NCE2027-04-28011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214998-001ODE-3982029-04-28011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214998-002M-2972026-06-15011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214998-002NCE2027-04-28011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214998-002ODE-3982029-04-28011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214998-003M-2972026-06-15011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214998-003NCE2027-04-28011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214998-003ODE-3982029-04-28011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214998-004M-2972026-06-15011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214998-004NCE2027-04-28011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214998-004ODE-3982029-04-28011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214998-001M-2972026-06-1531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214998-001NCE2027-04-2831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214998-001ODE-3982029-04-2831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214998-002M-2972026-06-1531067a03dcf5…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
CAMZYOSMAVACAMTENMyokardia, Inc.669c936b-3ee6-4e36-8a22-79dd11b1255b2025-04-17Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 214998
application number: NDA214998
ndc (product): 73625-111
ndc (product): 73625-114
ndc (product): 73625-112
ndc (product): 73625-113

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 16 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
73625-111CAMZYOSmavacamtenMyokardia, Inc.NDACurrent
73625-111CAMZYOSmavacamtenMyokardia, Inc.NDACurrent
73625-111CAMZYOSmavacamtenMyokardia, Inc.NDACurrent
73625-111CAMZYOSmavacamtenMyokardia, Inc.NDACurrent
73625-112CAMZYOSmavacamtenMyokardia, Inc.NDACurrent
73625-112CAMZYOSmavacamtenMyokardia, Inc.NDACurrent
73625-112CAMZYOSmavacamtenMyokardia, Inc.NDACurrent
73625-112CAMZYOSmavacamtenMyokardia, Inc.NDACurrent
73625-113CAMZYOSmavacamtenMyokardia, Inc.NDACurrent
73625-113CAMZYOSmavacamtenMyokardia, Inc.NDACurrent
73625-113CAMZYOSmavacamtenMyokardia, Inc.NDACurrent
73625-113CAMZYOSmavacamtenMyokardia, Inc.NDACurrent
73625-114CAMZYOSmavacamtenMyokardia, Inc.NDACurrent
73625-114CAMZYOSmavacamtenMyokardia, Inc.NDACurrent
73625-114CAMZYOSmavacamtenMyokardia, Inc.NDACurrent
73625-114CAMZYOSmavacamtenMyokardia, Inc.NDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
82024SUPPL 2025-04-28
81959SUPPL 2025-04-24
78655SUPPL 2024-06-05
78342SUPPL 2024-05-02
78341SUPPL 2024-05-02
77092SUPPL 2023-12-20
76367ORIG 2023-11-06
74525SUPPL 2023-06-16
74500SUPPL 2023-06-16
74499SUPPL 2023-06-16
73191SUPPL2023-01-17
72716SUPPL2022-11-25
71261ORIG2022-06-10
70885ORIG2022-05-02
70848ORIG2022-04-29