Application 215760

Type
NDA
Sponsor
ORPHALAN SA

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001CUVRIORTRIENTINE TETRAHYDROCHLORIDETABLET;ORAL300MGNoNo

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N215760-001CUVRIORTRIENTINE TETRAHYDROCHLORIDE300MGTABLET / ORALRLD, RS2022-04-28

Orange Book patents#

Current patent rows page 1 of 1 · 5 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N215760-001109884362039-05-03Drug substance2022-05-26
N215760-001110725772039-05-03U-33702022-05-26
N215760-001123588612039-05-03U-4262Drug substance, Drug product2025-09-22
N215760-001123588622039-05-03U-4262Drug substance, Drug product2025-09-22
N215760-001126624452039-05-03U-4262Drug substance, Drug product2026-07-06

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 1 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N215760-001ODE-4012029-04-28

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-28011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-2831067a03dcf5…
2025-08-23 18:47 UTC2025-08N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-286a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-28fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-28b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-2803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-282680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-285bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-28d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-28d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-2879d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-28301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-281e350fbaab3a…
2024-05-31 18:47 UTC2024-05N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-288072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-285c6f7cd8ea54…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-286a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-281c564ffb4f44…
2023-12-20 04:57 UTC2023-12N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-28ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-28a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-289b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-28a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-283f0d92c62455…
2023-05-13 08:27 UTC2023-05N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-28053a50430f4f…
2023-01-26 05:58 UTC2023-01N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-283bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-283a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-28f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-28e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-28cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N215760-001CUVRIOR300MGTABLET / ORALRLD, RS2022-04-28a50c72e98297…

Observed Orange Book patent history#

Patent history page 1 of 2 · 65 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N215760-001109884362039-05-03Drug substance2022-05-26011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215760-001110725772039-05-03U-33702022-05-26011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215760-001123588612039-05-03U-4262Drug substance, Drug product2025-09-22011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215760-001123588622039-05-03U-4262Drug substance, Drug product2025-09-22011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215760-001109884362039-05-03Drug substance2022-05-2631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215760-001110725772039-05-03U-33702022-05-2631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215760-001123588612039-05-03U-4262Drug substance, Drug product2025-09-2231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215760-001123588622039-05-03U-4262Drug substance, Drug product2025-09-2231067a03dcf5…
2025-08-23 18:47 UTC2025-08N215760-001109884362039-05-03Drug substance2022-05-266a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215760-001110725772039-05-03U-33702022-05-266a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215760-001109884362039-05-03Drug substance2022-05-26fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215760-001110725772039-05-03U-33702022-05-26fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N215760-001109884362039-05-03Drug substance2022-05-26b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N215760-001110725772039-05-03U-33702022-05-26b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N215760-001109884362039-05-03Drug substance2022-05-2603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N215760-001110725772039-05-03U-33702022-05-2603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N215760-001109884362039-05-03Drug substance2022-05-262680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N215760-001110725772039-05-03U-33702022-05-262680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N215760-001109884362039-05-03Drug substance2022-05-265bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N215760-001110725772039-05-03U-33702022-05-265bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N215760-001109884362039-05-03Drug substance2022-05-26d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N215760-001110725772039-05-03U-33702022-05-26d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N215760-001109884362039-05-03Drug substance2022-05-26d06236e962d9…
2024-10-29 15:01 UTC2024-10N215760-001110725772039-05-03U-33702022-05-26d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N215760-001109884362039-05-03Drug substance2022-05-2679d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N215760-001110725772039-05-03U-33702022-05-2679d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N215760-001109884362039-05-03Drug substance2022-05-26301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N215760-001110725772039-05-03U-33702022-05-26301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N215760-001109884362039-05-03Drug substance2022-05-261e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N215760-001110725772039-05-03U-33702022-05-261e350fbaab3a…
2024-05-31 18:47 UTC2024-05N215760-001109884362039-05-03Drug substance2022-05-268072bd15b7f6…
2024-05-31 18:47 UTC2024-05N215760-001110725772039-05-03U-33702022-05-268072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N215760-001109884362039-05-03Drug substance2022-05-265c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N215760-001110725772039-05-03U-33702022-05-265c6f7cd8ea54…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N215760-001109884362039-05-03Drug substance2022-05-266a51e52b5d6a…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N215760-001110725772039-05-03U-33702022-05-266a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N215760-001109884362039-05-03Drug substance2022-05-261c564ffb4f44…
2024-02-18 07:12 UTC2024-02N215760-001110725772039-05-03U-33702022-05-261c564ffb4f44…
2023-12-20 04:57 UTC2023-12N215760-001109884362039-05-03Drug substance2022-05-26ea1830bbd6c7…
2023-12-20 04:57 UTC2023-12N215760-001110725772039-05-03U-33702022-05-26ea1830bbd6c7…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 2 · 50 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-02-19 14:30 UTC2026-02N215760-001ODE-4012029-04-28011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215760-001NP2025-04-2831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215760-001ODE-4012029-04-2831067a03dcf5…
2025-08-23 18:47 UTC2025-08N215760-001NP2025-04-286a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215760-001ODE-4012029-04-286a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215760-001NP2025-04-28fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215760-001ODE-4012029-04-28fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N215760-001NP2025-04-28b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N215760-001ODE-4012029-04-28b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N215760-001NP2025-04-2803ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N215760-001ODE-4012029-04-2803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N215760-001NP2025-04-282680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N215760-001ODE-4012029-04-282680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N215760-001NP2025-04-285bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N215760-001ODE-4012029-04-285bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N215760-001NP2025-04-28d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N215760-001ODE-4012029-04-28d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N215760-001NP2025-04-28d06236e962d9…
2024-10-29 15:01 UTC2024-10N215760-001ODE-4012029-04-28d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N215760-001NP2025-04-2879d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N215760-001ODE-4012029-04-2879d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N215760-001NP2025-04-28301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N215760-001ODE-4012029-04-28301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N215760-001NP2025-04-281e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N215760-001ODE-4012029-04-281e350fbaab3a…
2024-05-31 18:47 UTC2024-05N215760-001NP2025-04-288072bd15b7f6…
2024-05-31 18:47 UTC2024-05N215760-001ODE-4012029-04-288072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N215760-001NP2025-04-285c6f7cd8ea54…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N215760-001NP2025-04-286a51e52b5d6a…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N215760-001ODE-4012029-04-286a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N215760-001NP2025-04-281c564ffb4f44…
2024-02-18 07:12 UTC2024-02N215760-001ODE-4012029-04-281c564ffb4f44…
2023-12-20 04:57 UTC2023-12N215760-001NP2025-04-28ea1830bbd6c7…
2023-12-20 04:57 UTC2023-12N215760-001ODE-4012029-04-28ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N215760-001NP2025-04-28a72a2bbeb626…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N215760-001ODE-4012029-04-28a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N215760-001NP2025-04-289b2671bbb829…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N215760-001ODE-4012029-04-289b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N215760-001NP2025-04-28a67488948f0b…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N215760-001ODE-4012029-04-28a67488948f0b…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
CUVRIORTRIENTINE TETRAHYDROCHLORIDEOrphalan SAf73feeae-62ad-401e-b9f7-5cb2691277502025-06-19Warnings, Adverse reactionsExact identifier
application applno (NDA): 215760
application number: NDA215760
ndc (product): 81802-001

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 1 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
81802-001CUVRIORTRIENTINE TETRAHYDROCHLORIDEOrphalan SANDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
74029ORIG 2023-04-20
70880ORIG2022-05-02
70851ORIG2022-04-29