Application 215904

Type
NDA
Sponsor
MARINUS PHARMA INC

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001ZTALMYGANAXOLONESUSPENSION;ORAL50MG/MLNoNo

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N215904-001ZTALMYGANAXOLONE50MG/MLSUSPENSION / ORALRLD, RS2022-06-01

Orange Book patents#

Current patent rows page 1 of 1 · 11 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N215904-00178586092026-11-28Drug product2022-06-02
N215904-00180220542026-11-28Drug product2022-06-02
N215904-00183676512026-11-28Drug product2022-06-02
N215904-00186180872026-11-28U-33742022-06-02
N215904-00190293552026-11-28Drug product2022-06-02
N215904-00190561162026-11-28U-33742022-06-02
N215904-00183187142031-11-28Drug product2022-06-02
N215904-001106033082037-08-10U-33742022-06-02
N215904-001121448012037-08-10U-40342024-11-21
N215904-001121151692042-09-30U-33742025-10-29
N215904-001122686962042-09-30U-33742025-10-29

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 3 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N215904-001NCE2027-06-01
N215904-001D-1972028-10-16
N215904-001ODE-3952029-06-01

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-01011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-0131067a03dcf5…
2025-08-23 18:47 UTC2025-08N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-016a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-01fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-01b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-0103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-012680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-015bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-01d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-01d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-0179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-01301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-011e350fbaab3a…
2024-05-31 18:47 UTC2024-05N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-018072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-016a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-011c564ffb4f44…
2023-12-20 04:57 UTC2023-12N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-01ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-01a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-019b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-01a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-013f0d92c62455…
2023-05-13 08:27 UTC2023-05N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-01053a50430f4f…
2023-01-26 05:58 UTC2023-01N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-013bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-013a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-01f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-01e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-01cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N215904-001ZTALMY50MG/MLSUSPENSION / ORALRLD, RS2022-06-01a50c72e98297…

Observed Orange Book patent history#

Patent history page 1 of 7 · 246 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N215904-00178586092026-11-28Drug product2022-06-02011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215904-00180220542026-11-28Drug product2022-06-02011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215904-00183187142026-11-28Drug product2022-06-02011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215904-00183676512026-11-28Drug product2022-06-02011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215904-00186180872026-11-28U-33742022-06-02011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215904-00190293552026-11-28Drug product2022-06-02011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215904-00190561162026-11-28U-33742022-06-02011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215904-001106033082037-08-10U-33742022-06-02011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215904-001121448012037-08-10U-40342024-11-21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215904-001121151692042-09-30U-33742025-10-29011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215904-001122686962042-09-30U-33742025-10-29011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215904-00178586092026-11-28Drug product2022-06-0231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215904-00180220542026-11-28Drug product2022-06-0231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215904-00183187142026-11-28Drug product2022-06-0231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215904-00183676512026-11-28Drug product2022-06-0231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215904-00186180872026-11-28U-33742022-06-0231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215904-00190293552026-11-28Drug product2022-06-0231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215904-00190561162026-11-28U-33742022-06-0231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215904-001106033082037-08-10U-33742022-06-0231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215904-001121448012037-08-10U-40342024-11-2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215904-001121151692042-09-30U-33742025-10-2931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215904-001122686962042-09-30U-33742025-10-2931067a03dcf5…
2025-08-23 18:47 UTC2025-08N215904-00178586092026-11-28Drug product2022-06-026a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215904-00180220542026-11-28Drug product2022-06-026a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215904-00183187142026-11-28Drug product2022-06-026a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215904-00183676512026-11-28Drug product2022-06-026a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215904-00186180872026-11-28U-33742022-06-026a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215904-00190293552026-11-28Drug product2022-06-026a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215904-00190561162026-11-28U-33742022-06-026a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215904-001106033082037-08-10U-33742022-06-026a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215904-001121448012037-08-10U-40342024-11-216a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215904-00178586092026-11-28Drug product2022-06-02fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215904-00180220542026-11-28Drug product2022-06-02fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215904-00183187142026-11-28Drug product2022-06-02fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215904-00183676512026-11-28Drug product2022-06-02fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215904-00186180872026-11-28U-33742022-06-02fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215904-00190293552026-11-28Drug product2022-06-02fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215904-00190561162026-11-28U-33742022-06-02fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215904-001106033082037-08-10U-33742022-06-02fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215904-001121448012037-08-10U-40342024-11-21fd3edfee7708…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 2 · 53 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-02-19 14:30 UTC2026-02N215904-001NCE2027-06-01011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215904-001D-1972028-10-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N215904-001ODE-3952029-06-01011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215904-001NCE2027-06-0131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N215904-001ODE-3952029-06-0131067a03dcf5…
2025-08-23 18:47 UTC2025-08N215904-001NCE2027-06-016a471c1ec25d…
2025-08-23 18:47 UTC2025-08N215904-001ODE-3952029-06-016a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215904-001NCE2027-06-01fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N215904-001ODE-3952029-06-01fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N215904-001NCE2027-06-01b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N215904-001ODE-3952029-06-01b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N215904-001NCE2027-06-0103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N215904-001ODE-3952029-06-0103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N215904-001NCE2027-06-012680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N215904-001ODE-3952029-06-012680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N215904-001NCE2027-06-015bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N215904-001ODE-3952029-06-015bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N215904-001NCE2027-06-01d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N215904-001ODE-3952029-06-01d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N215904-001NCE2027-06-01d06236e962d9…
2024-10-29 15:01 UTC2024-10N215904-001ODE-3952029-06-01d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N215904-001NCE2027-06-0179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N215904-001ODE-3952029-06-0179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N215904-001NCE2027-06-01301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N215904-001ODE-3952029-06-01301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N215904-001NCE2027-06-011e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N215904-001ODE-3952029-06-011e350fbaab3a…
2024-05-31 18:47 UTC2024-05N215904-001NCE2027-06-018072bd15b7f6…
2024-05-31 18:47 UTC2024-05N215904-001ODE-3952029-06-018072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N215904-001NCE2027-06-016a51e52b5d6a…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N215904-001ODE-3952029-06-016a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N215904-001NCE2027-06-011c564ffb4f44…
2024-02-18 07:12 UTC2024-02N215904-001ODE-3952029-06-011c564ffb4f44…
2023-12-20 04:57 UTC2023-12N215904-001NCE2027-06-01ea1830bbd6c7…
2023-12-20 04:57 UTC2023-12N215904-001ODE-3952029-06-01ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N215904-001NCE2027-06-01a72a2bbeb626…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N215904-001ODE-3952029-06-01a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N215904-001NCE2027-06-019b2671bbb829…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N215904-001ODE-3952029-06-019b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N215904-001NCE2027-06-01a67488948f0b…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
ZTALMYGANAXOLONEImmedica Pharma US Incd91612c4-b03a-4be4-a1ee-6a13e3b83d4e2025-11-28Warnings, Adverse reactionsExact identifier
application applno (NDA): 215904
application number: NDA215904
ndc (product): 81583-100

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 2 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
81583-100ZTALMYganaxoloneMarinus Pharmaceuticals, Inc.NDACurrent
81583-100ZTALMYganaxoloneMarinus Pharmaceuticals, Inc.NDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
83845SUPPL 2025-10-21
83844SUPPL 2025-10-21
83843SUPPL 2025-10-21
83812SUPPL 2025-10-20
83811SUPPL 2025-10-20
83126SUPPL 2025-08-19
83060SUPPL 2025-08-07
74607SUPPL 2023-06-22
74605SUPPL 2023-06-22
74586SUPPL 2023-06-22
74585SUPPL 2023-06-22
72598SUPPL2022-11-10
72597SUPPL2022-11-10
72594SUPPL2022-11-10
72593SUPPL2022-11-10
72592SUPPL2022-11-10
71205ORIG2022-06-03
70751ORIG2022-04-12
70577ORIG2022-03-22
70738ORIG2022-03-18
70737ORIG2022-03-18
70558ORIG2022-03-18