Application 216117

Type
NDA
Sponsor
OSMOTICA PHARM CORP

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001RELEXXIIMETHYLPHENIDATE HYDROCHLORIDETABLET, EXTENDED RELEASE;ORAL18MGYesNo
002RELEXXIIMETHYLPHENIDATE HYDROCHLORIDETABLET, EXTENDED RELEASE;ORAL27MGYesNo
003RELEXXIIMETHYLPHENIDATE HYDROCHLORIDETABLET, EXTENDED RELEASE;ORAL36MGYesNo
004RELEXXIIMETHYLPHENIDATE HYDROCHLORIDETABLET, EXTENDED RELEASE;ORAL45MGYesNo
005RELEXXIIMETHYLPHENIDATE HYDROCHLORIDETABLET, EXTENDED RELEASE;ORAL54MGYesNo
006RELEXXIIMETHYLPHENIDATE HYDROCHLORIDETABLET, EXTENDED RELEASE;ORAL63MGYesNo
007RELEXXIIMETHYLPHENIDATE HYDROCHLORIDETABLET, EXTENDED RELEASE;ORAL72MGYesNo

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 7 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N216117-001RELEXXIIMETHYLPHENIDATE HYDROCHLORIDE18MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-23
N216117-002RELEXXIIMETHYLPHENIDATE HYDROCHLORIDE27MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-23
N216117-003RELEXXIIMETHYLPHENIDATE HYDROCHLORIDE36MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-23
N216117-004RELEXXIIMETHYLPHENIDATE HYDROCHLORIDE45MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-23
N216117-005RELEXXIIMETHYLPHENIDATE HYDROCHLORIDE54MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-23
N216117-006RELEXXIIMETHYLPHENIDATE HYDROCHLORIDE63MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-23
N216117-007RELEXXIIMETHYLPHENIDATE HYDROCHLORIDE72MGTABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-23

Orange Book patents#

Current patent rows page 1 of 1 · 35 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N216117-001102653082037-02-03U-4032Drug product2024-11-18
N216117-001106953362037-02-03U-40322024-11-18
N216117-00197072172037-02-03Drug product2024-11-18
N216117-00198272342037-02-03U-40322024-11-18
N216117-00198552582037-02-03U-4032Drug product2024-11-18
N216117-002102653082037-02-03U-4032Drug product2024-11-18
N216117-002106953362037-02-03U-40322024-11-18
N216117-00297072172037-02-03Drug product2024-11-18
N216117-00298272342037-02-03U-40322024-11-18
N216117-00298552582037-02-03U-4032Drug product2024-11-18
N216117-003102653082037-02-03U-4032Drug product2024-11-18
N216117-003106953362037-02-03U-40322024-11-18
N216117-00397072172037-02-03Drug product2024-11-18
N216117-00398272342037-02-03U-40322024-11-18
N216117-00398552582037-02-03U-4032Drug product2024-11-18
N216117-004102653082037-02-03U-4032Drug product2024-11-18
N216117-004106953362037-02-03U-40322024-11-18
N216117-00497072172037-02-03Drug product2024-11-18
N216117-00498272342037-02-03U-40322024-11-18
N216117-00498552582037-02-03U-4032Drug product2024-11-18
N216117-005102653082037-02-03U-4032Drug product2024-11-18
N216117-005106953362037-02-03U-40322024-11-18
N216117-00597072172037-02-03Drug product2024-11-18
N216117-00598272342037-02-03U-40322024-11-18
N216117-00598552582037-02-03U-4032Drug product2024-11-18
N216117-006102653082037-02-03U-4032Drug product2024-11-18
N216117-006106953362037-02-03U-40322024-11-18
N216117-00697072172037-02-03Drug product2024-11-18
N216117-00698272342037-02-03U-40322024-11-18
N216117-00698552582037-02-03U-4032Drug product2024-11-18
N216117-007102653082037-02-03U-4032Drug product2024-11-18
N216117-007106953362037-02-03U-40322024-11-18
N216117-00797072172037-02-03Drug product2024-11-18
N216117-00798272342037-02-03U-40322024-11-18
N216117-00798552582037-02-03U-4032Drug product2024-11-18

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 5 · 196 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N216117-001RELEXXII18MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-23011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-002RELEXXII27MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-23011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-003RELEXXII36MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-23011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-004RELEXXII45MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-23011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-005RELEXXII54MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-23011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-006RELEXXII63MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-23011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-007RELEXXII72MGTABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-23011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216117-001RELEXXII18MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-2331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216117-002RELEXXII27MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-2331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216117-003RELEXXII36MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-2331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216117-004RELEXXII45MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-2331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216117-005RELEXXII54MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-2331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216117-006RELEXXII63MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-2331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216117-007RELEXXII72MGTABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-2331067a03dcf5…
2025-08-23 18:47 UTC2025-08N216117-001RELEXXII18MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-236a471c1ec25d…
2025-08-23 18:47 UTC2025-08N216117-002RELEXXII27MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-236a471c1ec25d…
2025-08-23 18:47 UTC2025-08N216117-003RELEXXII36MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-236a471c1ec25d…
2025-08-23 18:47 UTC2025-08N216117-004RELEXXII45MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-236a471c1ec25d…
2025-08-23 18:47 UTC2025-08N216117-005RELEXXII54MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-236a471c1ec25d…
2025-08-23 18:47 UTC2025-08N216117-006RELEXXII63MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-236a471c1ec25d…
2025-08-23 18:47 UTC2025-08N216117-007RELEXXII72MGTABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-236a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N216117-001RELEXXII18MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-23fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N216117-002RELEXXII27MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-23fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N216117-003RELEXXII36MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-23fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N216117-004RELEXXII45MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-23fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N216117-005RELEXXII54MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-23fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N216117-006RELEXXII63MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-23fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N216117-007RELEXXII72MGTABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-23fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N216117-001RELEXXII18MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-23b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N216117-002RELEXXII27MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-23b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N216117-003RELEXXII36MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-23b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N216117-004RELEXXII45MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-23b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N216117-005RELEXXII54MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-23b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N216117-006RELEXXII63MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-23b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N216117-007RELEXXII72MGTABLET, EXTENDED RELEASE / ORALRLD, RS2022-06-23b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N216117-001RELEXXII18MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-2303ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N216117-002RELEXXII27MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-2303ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N216117-003RELEXXII36MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-2303ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N216117-004RELEXXII45MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-2303ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N216117-005RELEXXII54MGTABLET, EXTENDED RELEASE / ORALRLD2022-06-2303ed91905a0d…

Observed Orange Book patent history#

Patent history page 1 of 7 · 280 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N216117-001102653082037-02-03U-4032Drug product2024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-001106953362037-02-03U-40322024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-00197072172037-02-03Drug product2024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-00198272342037-02-03U-40322024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-00198552582037-02-03U-4032Drug product2024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-002102653082037-02-03U-4032Drug product2024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-002106953362037-02-03U-40322024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-00297072172037-02-03Drug product2024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-00298272342037-02-03U-40322024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-00298552582037-02-03U-4032Drug product2024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-003102653082037-02-03U-4032Drug product2024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-003106953362037-02-03U-40322024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-00397072172037-02-03Drug product2024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-00398272342037-02-03U-40322024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-00398552582037-02-03U-4032Drug product2024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-004102653082037-02-03U-4032Drug product2024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-004106953362037-02-03U-40322024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-00497072172037-02-03Drug product2024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-00498272342037-02-03U-40322024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-00498552582037-02-03U-4032Drug product2024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-005102653082037-02-03U-4032Drug product2024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-005106953362037-02-03U-40322024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-00597072172037-02-03Drug product2024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-00598272342037-02-03U-40322024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-00598552582037-02-03U-4032Drug product2024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-006102653082037-02-03U-4032Drug product2024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-006106953362037-02-03U-40322024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-00697072172037-02-03Drug product2024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-00698272342037-02-03U-40322024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-00698552582037-02-03U-4032Drug product2024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-007102653082037-02-03U-4032Drug product2024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-007106953362037-02-03U-40322024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-00797072172037-02-03Drug product2024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-00798272342037-02-03U-40322024-11-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N216117-00798552582037-02-03U-4032Drug product2024-11-18011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216117-001102653082037-02-03U-4032Drug product2024-11-1831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216117-001106953362037-02-03U-40322024-11-1831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216117-00197072172037-02-03Drug product2024-11-1831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216117-00198272342037-02-03U-40322024-11-1831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N216117-00198552582037-02-03U-4032Drug product2024-11-1831067a03dcf5…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
RELEXXIIMETHYLPHENIDATE HYDROCHLORIDEVertical Pharmaceuticals, LLC22d5fa47-b5b9-4fd9-980c-4eb88e95ae5d2025-09-26Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 216117
application number: NDA216117
ndc (product): 68025-089
ndc (product): 68025-088
Methylphenidate HydrochlorideMETHYLPHENIDATE HYDROCHLORIDETrigen Laboratories, LLCdd8d7b6e-c23d-4e16-bb53-959e9127ebc62025-09-26Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 216117
application number: NDA216117
ndc (product): 13811-711
ndc (product): 13811-700

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 4 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
13811-700Methylphenidate HydrochlorideMethylphenidate hydrochlorideTrigen Laboratories, LLCNDACurrent
13811-711Methylphenidate HydrochlorideMethylphenidate hydrochlorideTrigen Laboratories, LLCNDACurrent
68025-088RELEXXIImethylphyenidate hydrochloride extended-releaseVertical Pharmaceuticals, LLCNDACurrent
68025-089RELEXXIImethylphyenidate hydrochloride extended-releaseVertical Pharmaceuticals, LLCNDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
83515SUPPL 2025-09-25
83514SUPPL 2025-09-25
83466SUPPL 2025-09-25
75805SUPPL 2023-10-17
75763SUPPL 2023-10-16
74191ORIG 2023-05-09
71450ORIG2022-06-24
71445ORIG2022-06-24