Indications and uses
Uses temporarily relieves minor aches and pains due to: headache toothache backache menstrual cramps muscular aches minor pain of arthritis
Uses temporarily relieves minor aches and pains due to: headache toothache backache menstrual cramps muscular aches minor pain of arthritis
Directions Do not take more than directed adults and children 12 years and over take 2 caplets every 8 hours while symptoms persist children under 12 years ask a doctor do not take more than 6 caplets in 24 hours, unless directed by a doctor
Drug Facts
Active ingredients
Acetaminophen 250 mg
Ibuprofen 125 mg (NSAID*)
*nonsteroidal anti-inflammatory drug
Purposes
Pain reliever
Pain reliever
Uses
Warnings
Acetaminophen liver damage warning:
This product contains acetaminophen.
Severe liver damage may occur if you take:
Acetaminophen allergy alert: may cause severe skin reactions. Symptoms may include:
If skin reaction occurs, stop use and seek medical help right away.
NSAID allergy alert: ibuprofen may cause a severe allergic reaction, especially in people allergic to aspirin. Symptoms may include:
If an allergic reaction occurs, stop use and seek medical help right away.
NSAID stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you:
Heart attackand stroke warning: NSAIDs, except aspirin, increase the risk of heart attack, heart failure, and stroke. These can be fatal. The risk is higher if you use more than directed or for longer than directed.
Do not use
Ask a doctor before use if
Ask a doctor or pharmacist before use if you are
When using this product
Stop use and ask a doctor if
If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use ibuprofen at 20 weeks or later in pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Directions
| adults and children 12 years and over |
|
| children under 12 years |
|
Other information
Inactive ingredients
carnauba wax, colloidal silicon dioxide, croscarmellose sodium, ferric oxides, glyceryl dibehenate, hypromellose, pharmaceutical ink, polydextrose, polyethylene glycol, pregelatinized starch, titanium dioxide
Questions or comments? call weekdays 9 AM to 5 PM at 1-800-88-ADVIL
Advil
Dual Action
with Acetaminophen
[caplet image]
Acetaminophen 250 mg and
Ibuprofen
(NSAID) 125 mg Tablets
Pain Reliever
6 Caplets*
*Capsule-Shaped Tablets
[Lil' Drug Store logo]
Advil
Dual Action
with Acetaminophen
[caplet image]
Acetaminophen 250 mg and
Ibuprofen
(NSAID) 125 mg Tablets
Pain Reliever
4 Caplets*
*Capsule-Shaped Tablets
[Travel BASIX logo]
| Class | Version | Type | Effective |
|---|---|---|---|
| IBUPROFEN Pharmacologic Class Indexing | 2 | Indexing - Pharmacologic Class | 20191108 |
| NDC | Effective | Action | Document | Indexing SPL | Related label |
|---|---|---|---|---|---|
| 66715-9601-3 | 2024-01-30 | C162847 | 48780-1 | 1030e364-fcc9-111a-e063-dadaa90a10e2 | Advil Dual Action with Acetaminophen |
| Package NDC | Product | Description | Form | Quantity | Strength | SPL version |
|---|---|---|---|---|---|---|
| 66715-6401-2 | Advil Dual Action with Acetaminophen, Travel BASIX | 2 in 1 POUCH | TABLET, FILM COATED | 2 | 4 | |
| 66715-6401-2 | Advil Dual Action with Acetaminophen, Travel BASIX | 2 in 1 CARTON | TABLET, FILM COATED | 2 | 4 | |
| 66715-9601-2 | Advil Dual Action with Acetaminophen | 2 in 1 CARTON | TABLET, FILM COATED | 2 | 4 | |
| 66715-9601-2 | Advil Dual Action with Acetaminophen | 2 in 1 POUCH | TABLET, FILM COATED | 2 | 4 | |
| 66715-9601-3 | Advil Dual Action with Acetaminophen | 2 in 1 POUCH | TABLET, FILM COATED | 2 | 4 | |
| 66715-9601-3 | Advil Dual Action with Acetaminophen | 3 in 1 CARTON | TABLET, FILM COATED | 3 | 4 |
Every source-derived product name is available through these pages.
| Product NDC | Package NDC |
|---|---|
| 66715-9601 | 66715-9601-3, 66715-9601-2 |
| 66715-6401 | 66715-6401-2 |
Every source-derived ingredient row is available through these pages.
All distinct exact application/product contexts derived from this label’s complete NDC list are paginated below.
| Application-product | Trade name | Ingredient | Strength | Dosage form / route | TE codes | RLD / RS | Approval date |
|---|---|---|---|---|---|---|---|
| N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | ACETAMINOPHEN; IBUPROFEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 |
| Application-product | Patent | Expiration | Use code | Coverage / status | Submission date |
|---|---|---|---|---|---|
| N211733-001 | 11918693 | 2041-07-09 | Drug product | 2024-03-26 |
Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.
| Captured | Edition | Application-product | Trade name | Strength | Dosage form / route | Product TE source text | RLD / RS | Approval date | Source SHA-256 |
|---|---|---|---|---|---|---|---|---|---|
| 2026-09-14 22:38:34 | 2026-08 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | 84e616aacf4f… | |
| 2026-08-18 06:07:40 | 2026-07 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | caaa826d4ba7… | |
| 2026-02-19 14:30 UTC | 2026-02 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | 011fe1cb6892… | |
| 2025-12-14 10:44 UTC · 2 captures of this ZIP | 2025-12 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | 31067a03dcf5… | |
| 2025-08-23 18:47 UTC | 2025-08 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | 6a471c1ec25d… | |
| 2025-03-22 03:13 UTC · 3 captures of this ZIP | 2025-03 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | fd3edfee7708… | |
| 2025-02-26 10:13 UTC · 3 captures of this ZIP | 2025-02 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | b8a1b40f171c… | |
| 2025-01-19 17:59 UTC · 7 captures of this ZIP | 2025-01 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | 03ed91905a0d… | |
| 2024-12-13 21:23 UTC · 2 captures of this ZIP | 2024-12 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | 2680178bc6a6… | |
| 2024-09-14 05:58 UTC · 2 captures of this ZIP | 2024-09 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | 5bbf6a4d5a75… | |
| 2024-11-08 22:44 UTC · 3 captures of this ZIP | 2024-11 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | d8e5a09893c0… | |
| 2024-10-29 15:01 UTC | 2024-10 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | d06236e962d9… | |
| 2024-08-13 05:28 UTC · 3 captures of this ZIP | 2024-08 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | 79d66fd596c7… | |
| 2024-07-13 05:37 UTC · 2 captures of this ZIP | 2024-07 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | 301d65b070ca… | |
| 2024-06-18 03:08 UTC · 5 captures of this ZIP | 2024-06 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | 1e350fbaab3a… | |
| 2024-05-31 18:47 UTC | 2024-05 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | 8072bd15b7f6… | |
| 2022-06-29 02:47 UTC · 2 captures of this ZIP | 2022-06 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | 5c6f7cd8ea54… | |
| 2022-04-08 23:34 UTC | 2022-04 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | 5d02ea3f76ae… | |
| 2022-04-04 05:41 UTC | 2022-04 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | 4b0b4de00fa7… | |
| 2022-03-09 01:35 UTC | 2022-03 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | bb7c543d1eb4… | |
| 2021-12-28 21:50 UTC | 2021-12 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | 782e0a99824c… | |
| 2021-05-05 16:15 UTC · 3 captures of this ZIP | 2021-05 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | 87673890dc5c… | |
| 2021-03-12 10:30 UTC | 2021-03 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | 5aa47cf7b7d7… | |
| 2020-12-22 03:56 UTC | 2020-12 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | 8869cabd3fbd… | |
| 2020-11-12 02:37 UTC | 2020-11 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | c0c555d07b60… | |
| 2024-03-16 18:09 UTC · 4 captures of this ZIP | 2024-03 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | 6a51e52b5d6a… | |
| 2024-02-18 07:12 UTC | 2024-02 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | 1c564ffb4f44… | |
| 2023-12-20 04:57 UTC | 2023-12 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | ea1830bbd6c7… | |
| 2023-11-28 05:40 UTC · 2 captures of this ZIP | 2023-11 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | a72a2bbeb626… | |
| 2023-10-25 00:34 UTC · 2 captures of this ZIP | 2023-10 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | 9b2671bbb829… | |
| 2023-07-15 15:27 UTC · 2 captures of this ZIP | 2023-07 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | a67488948f0b… | |
| 2023-06-13 01:57 UTC · 3 captures of this ZIP | 2023-06 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | 3f0d92c62455… | |
| 2023-05-13 08:27 UTC | 2023-05 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | 053a50430f4f… | |
| 2023-01-26 05:58 UTC | 2023-01 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | 3bdfa0b2c4d7… | |
| 2022-11-12 20:34 UTC · 5 captures of this ZIP | 2022-11 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | 3a93d1ddd44b… | |
| 2022-10-28 04:53 UTC | 2022-10 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | f41ea6bd6efb… | |
| 2022-09-29 23:25 UTC | 2022-09 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | e64feba35796… | |
| 2022-07-09 03:26 UTC · 3 captures of this ZIP | 2022-07 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | cb3db0bc1861… | |
| 2026-07-26 02:55 UTC · 3 captures of this ZIP | 2026-06 | N211733-001 | ADVIL DUAL ACTION WITH ACETAMINOPHEN | 250MG;125MG | TABLET / ORAL | RLD, RS | 2020-02-28 | a50c72e98297… |
| Captured | Edition | Application-product | Patent | Expiration | Use code | Coverage / status | Submission date | Source SHA-256 |
|---|---|---|---|---|---|---|---|---|
| 2026-09-14 22:38:34 | 2026-08 | N211733-001 | 11918693 | 2041-07-09 | Drug product | 2024-03-26 | 84e616aacf4f… | |
| 2026-08-18 06:07:40 | 2026-07 | N211733-001 | 11918693 | 2041-07-09 | Drug product | 2024-03-26 | caaa826d4ba7… | |
| 2026-02-19 14:30 UTC | 2026-02 | N211733-001 | 11918693 | 2041-07-09 | Drug product | 2024-03-26 | 011fe1cb6892… | |
| 2025-12-14 10:44 UTC · 2 captures of this ZIP | 2025-12 | N211733-001 | 11918693 | 2041-07-09 | Drug product | 2024-03-26 | 31067a03dcf5… | |
| 2025-08-23 18:47 UTC | 2025-08 | N211733-001 | 11918693 | 2041-07-09 | Drug product | 2024-03-26 | 6a471c1ec25d… | |
| 2025-03-22 03:13 UTC · 3 captures of this ZIP | 2025-03 | N211733-001 | 11918693 | 2041-07-09 | Drug product | 2024-03-26 | fd3edfee7708… | |
| 2025-02-26 10:13 UTC · 3 captures of this ZIP | 2025-02 | N211733-001 | 11918693 | 2041-07-09 | Drug product | 2024-03-26 | b8a1b40f171c… | |
| 2025-01-19 17:59 UTC · 7 captures of this ZIP | 2025-01 | N211733-001 | 11918693 | 2041-07-09 | Drug product | 2024-03-26 | 03ed91905a0d… | |
| 2024-12-13 21:23 UTC · 2 captures of this ZIP | 2024-12 | N211733-001 | 11918693 | 2041-07-09 | Drug product | 2024-03-26 | 2680178bc6a6… | |
| 2024-09-14 05:58 UTC · 2 captures of this ZIP | 2024-09 | N211733-001 | 11918693 | 2041-07-09 | Drug product | 2024-03-26 | 5bbf6a4d5a75… | |
| 2024-11-08 22:44 UTC · 3 captures of this ZIP | 2024-11 | N211733-001 | 11918693 | 2041-07-09 | Drug product | 2024-03-26 | d8e5a09893c0… | |
| 2024-10-29 15:01 UTC | 2024-10 | N211733-001 | 11918693 | 2041-07-09 | Drug product | 2024-03-26 | d06236e962d9… | |
| 2024-08-13 05:28 UTC · 3 captures of this ZIP | 2024-08 | N211733-001 | 11918693 | 2041-07-09 | Drug product | 2024-03-26 | 79d66fd596c7… | |
| 2024-07-13 05:37 UTC · 2 captures of this ZIP | 2024-07 | N211733-001 | 11918693 | 2041-07-09 | Drug product | 2024-03-26 | 301d65b070ca… | |
| 2024-06-18 03:08 UTC · 5 captures of this ZIP | 2024-06 | N211733-001 | 11918693 | 2041-07-09 | Drug product | 2024-03-26 | 1e350fbaab3a… | |
| 2024-05-31 18:47 UTC | 2024-05 | N211733-001 | 11918693 | 2041-07-09 | Drug product | 2024-03-26 | 8072bd15b7f6… | |
| 2026-07-26 02:55 UTC · 3 captures of this ZIP | 2026-06 | N211733-001 | 11918693 | 2041-07-09 | Drug product | 2024-03-26 | a50c72e98297… |
| Captured | Edition | Application-product | Exclusivity code | Expiration | Source SHA-256 |
|---|---|---|---|---|---|
| 2022-06-29 02:47 UTC · 2 captures of this ZIP | 2022-06 | N211733-001 | NP | 2023-02-28 | 5c6f7cd8ea54… |
| 2022-04-08 23:34 UTC | 2022-04 | N211733-001 | NP | 2023-02-28 | 5d02ea3f76ae… |
| 2022-04-04 05:41 UTC | 2022-04 | N211733-001 | NP | 2023-02-28 | 4b0b4de00fa7… |
| 2022-03-09 01:35 UTC | 2022-03 | N211733-001 | NP | 2023-02-28 | bb7c543d1eb4… |
| 2021-12-28 21:50 UTC | 2021-12 | N211733-001 | NP | 2023-02-28 | 782e0a99824c… |
| 2021-05-05 16:15 UTC · 3 captures of this ZIP | 2021-05 | N211733-001 | NP | 2023-02-28 | 87673890dc5c… |
| 2021-03-12 10:30 UTC | 2021-03 | N211733-001 | NP | 2023-02-28 | 5aa47cf7b7d7… |
| 2020-12-22 03:56 UTC | 2020-12 | N211733-001 | NP | 2023-02-28 | 8869cabd3fbd… |
| 2020-11-12 02:37 UTC | 2020-11 | N211733-001 | NP | 2023-02-28 | c0c555d07b60… |
| 2023-12-20 04:57 UTC | 2023-12 | N211733-001 | NP | 2023-02-28 | ea1830bbd6c7… |
| 2023-11-28 05:40 UTC · 2 captures of this ZIP | 2023-11 | N211733-001 | NP | 2023-02-28 | a72a2bbeb626… |
| 2023-10-25 00:34 UTC · 2 captures of this ZIP | 2023-10 | N211733-001 | NP | 2023-02-28 | 9b2671bbb829… |
| 2023-07-15 15:27 UTC · 2 captures of this ZIP | 2023-07 | N211733-001 | NP | 2023-02-28 | a67488948f0b… |
| 2023-06-13 01:57 UTC · 3 captures of this ZIP | 2023-06 | N211733-001 | NP | 2023-02-28 | 3f0d92c62455… |
| 2023-05-13 08:27 UTC | 2023-05 | N211733-001 | NP | 2023-02-28 | 053a50430f4f… |
| 2023-01-26 05:58 UTC | 2023-01 | N211733-001 | NP | 2023-02-28 | 3bdfa0b2c4d7… |
| 2022-11-12 20:34 UTC · 5 captures of this ZIP | 2022-11 | N211733-001 | NP | 2023-02-28 | 3a93d1ddd44b… |
| 2022-10-28 04:53 UTC | 2022-10 | N211733-001 | NP | 2023-02-28 | f41ea6bd6efb… |
| 2022-09-29 23:25 UTC | 2022-09 | N211733-001 | NP | 2023-02-28 | e64feba35796… |
| 2022-07-09 03:26 UTC · 3 captures of this ZIP | 2022-07 | N211733-001 | NP | 2023-02-28 | cb3db0bc1861… |
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| Advil Dual Action with Acetaminophen, Travel BASIX | IBUPROFEN, ACETAMINOPHEN TABLET, FILM COATED | Lil' Drug Store Products, Inc. | 030d9bca-a934-6ef9-e063-6394a90a8277 | 2025-12-01 | Warnings | 66715-9601-3 66715-6401-2 66715-9601-2 66715-6401 66715-9601 66715960102 66715960103 66715640102 44e71018-211d-caf8-e063-6394a90a06c9 030d9bca-a934-6ef9-e063-6394a90a8277 |
Adverse event summaries are temporarily unavailable. Other product information remains available.