Acne Relief Retinol Treatment and Moisturizer
- Manufacturer
- NV Perricone LLC
- Effective date
- 2022-02-10
- Label type
- HUMAN OTC DRUG LABEL
- Version
- 2
- Source
- full-release
- Hydrated at
- 2026-05-31 23:48:10
Label at a glance#
Contacts and useful links#
Label contents#
Full prescribing information#
SPL UNCLASSIFIED SECTION
Drug Facts
OTC - ACTIVE INGREDIENT SECTION
Active Ingredient
Salicylic Acid 0.5%
OTC - PURPOSE SECTION
Purpose
Acne Treatment
INDICATIONS & USAGE SECTION
Use
■ For the treatment of acne.
WARNINGS SECTION
Warnings
■ For external use only.
■ When Using This Product Skin irritation and dryness are
more likely to occur if you use another topical acne medication
at the same time.
■ If irritation occurs, only use one topical acne medication at a time.
■ Keep out of reach of children. If swallowed, get medical
help or contact a Poison Control Center right away.
DOSAGE & ADMINISTRATION SECTION
Directions
■ Shake well. Apply a thin, even layer to skin in the evening.
For best results, use after cleansing with ACNE RELIEF
Gentle & Soothing Cleanser.
■ Clean the skin thoroughly before applying this product.
■ Cover the entire affected area with a thin layer one to three
times daily.
■ Because excessive drying of the skin may occur, start with
one application daily, then gradually increase to two or
three times daily if needed or as directed by a doctor.
■ If bothersome dryness or peeling occurs, reduce application
to once a day or every other day.
■ Sensitivity Test for a New User Apply product sparingly
to one or two small affected areas during the first 3 days.
If no discomfort occurs, follow the directions stated above.
INACTIVE INGREDIENT SECTION
Inactive Ingredients Water/Aqua/Eau, SD Alcohol 40-B,
Glycerin, Dicaprylyl Ether, Niacinamide, Citrulline, Arginine, Methyl
Gluceth-20, Cetearyl Alcohol, Carbomer, Xanthan Gum, Tocopheryl
Acetate, Retinol, Citric Acid, Sodium Hydroxide, Disodium
EDTA, PEG-20 Methyl Glucose Sesquistearate, PEG-100 Stearate,
Glyceryl Stearate, Methyl Glucose Sesquistearate, Polysorbate
20, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate
OTC - QUESTIONS SECTION
Questions 1-888-823-7837
Product Package
ACNE RELIEF
Retinol Treatment
& Moisturizer
Controls excess oil & fights
blemishes overnight
STEP 2
NIGHT
Perricone MD
ACNE RELIEF
Retinol Treatment
& Moisturizer
Salicylic Acid
Acne Treatment
90 DAY SUPPLY
Niacinamide, Citrulline,
Retinol
℮ 59 mL / 2 fl oz
KEY INGREDIENTS
Niacinamide: Gentle Skin-
Clearing Multi-Tasker Also
known as vitamin B3 & found in
foods such as tomatoes, this skin-
clearing powerhouse helps to
gently & visibly erase imperfections,
unclog oily pores & minimize
redness & uneven skin tone that
can be left behind after breakouts
by improving skin’s moisture
barrier. B3 is a powerful antioxidant
& an essential nutrient
that plays a key role in many of
the body’s basic functions.
Citrulline: Fight Irritation &
Visibly Reduce Redness First
discovered in watermelon, this
alpha-amino acid visibly calms
skin for a clearer, more even-
looking complexion. Nourishing
& soothing, it is an ideal way to
counteract the irritating effects
of anti-acne ingredients.
Retinol: Exfoliate for Clearer
Skin & Accelerated Rejuvenation
This ultra-powerful, non-prescription
vitamin A derivative helps
prevent breakouts by unclogging
pores & accelerating surface skin
exfoliation & renewal. Unique
slow-release carrier system helps
preserve this unstable ingredient
& calm skin.
Expiration &
Lot Code area
Perricone MD ACNE RELIEF
Prebiotic Acne Therapy is a
simple, comprehensive system
that works with your surface
skin’s natural microbiome to
safely, gently & effectively treat
& prevent the most troublesome
acne, while restoring &
maintaining a healthy skin
balance, for clearer, blemish-
free skin. This powerful 2-step
regimen is clinically proven to
be non-irritating & will not
strip or over-dry skin.
The Retinol Treatment & Moisturizer
is Step 2 in your night
regimen, after cleansing. The
lightweight yet nourishing
formula absorbs instantly to
control excess oil & helps to
heal blemishes while you sleep
without over-drying the skin.
The powerful combination of
retinol, citrulline & niacinamide
helps to accelerate surface
skin exfoliation & renewal, visibly
calm skin & reduce redness,
while gently & visibly erasing
imperfections overnight.
Dist. By: NV Perricone LLC, San Francisco,
CA 94111. Made in USA of foreign and
domestic components. 651197
1 888 823 7837
perriconemd.com
Outer Box
Bottle
rege
DailyMed RxNorm Mappings#
DailyMed Product Concepts#
| Product concept | Relation | Version | Effective |
|---|---|---|---|
| c6f86816-7da6-43ea-8c25-ac9758311cc5 | Product name | 1 | 20220118 |
| dea2eded-d1e7-46bb-9a3d-f8dc20de6277 | Product name | 1 | 20190408 |
| 7792dadb-52b6-46b6-8fdf-80b1171065b5 | Product name | 1 | 20180810 |
| 252e11b6-1a9a-4283-a242-df2c129c496d | Product name | 3 | 20170717 |
| 0ca1d589-929b-4b33-bc5b-1d84abdafa6a | Product name | 1 | 20150324 |
| fc363c46-397b-4476-ac0f-70e43e8e4592 | Product name | 1 | 20150324 |
| 1681bc73-b05f-12c3-1075-382ae39f449c | Product name | 1 | 20140508 |
FDA-Initiated Inactive NDC Indexing#
| NDC | Effective | Action | Document | Indexing SPL | Related label |
|---|---|---|---|---|---|
| 45634-101-01 | 2024-01-30 | C162847 | 48780-1 | ba0f9c33-45b4-a910-e053-dadaa90a0b85 | ACNE RELIEF RETINOL TREATMENT & MOISTURIZER STEP 2 - NIGHT |
| 45634-101-01 | 2022-02-10 | C162847 | 48780-1 | ba0f9c33-45b4-a910-e053-dadaa90a0b85 | ACNE RELIEF RETINOL TREATMENT & MOISTURIZER STEP 2 - NIGHT |
| 45634-101-01 | 2021-01-29 | C162847 | 48780-1 | ba0f9c33-45b4-a910-e053-dadaa90a0b85 | ACNE RELIEF RETINOL TREATMENT & MOISTURIZER STEP 2 - NIGHT |
DailyMed Package Descriptions#
| Package NDC | Product | Description | Form | Quantity | Strength | SPL version |
|---|---|---|---|---|---|---|
| 45634-101-01 | Acne Relief Retinol Treatment and Moisturizer | 1 in 1 PACKAGE | LOTION | 1 | 2 | |
| 45634-101-01 | Acne Relief Retinol Treatment and Moisturizer | 59 mL in 1 BOTTLE, DROPPER | LOTION | 59 | 2 |
DailyMed Dashboard NDC Coverage#
Products#
Every source-derived product name is available through these pages.
- Acne Relief Retinol Treatment and Moisturizer
- Salicylic Acid Acne Treatment
- SALICYLIC ACID
- WATER
- ALCOHOL
- GLYCERIN
- DICAPRYLYL ETHER
- NIACINAMIDE
- CITRULLINE
- ARGININE
- METHYL GLUCETH-20
- CETOSTEARYL ALCOHOL
- CARBOXYPOLYMETHYLENE
- PHENOXYETHANOL
- CITRIC ACID MONOHYDRATE
- PEG-20 METHYL GLUCOSE SESQUISTEARATE
- PEG-100 STEARATE
- GLYCERYL MONOSTEARATE
- METHYL GLUCOSE SESQUISTEARATE
- XANTHAN GUM
- SODIUM HYDROXIDE
- .ALPHA.-TOCOPHEROL ACETATE
- SODIUM BENZOATE
- RETINOL
- POLYSORBATE 20
- EDETATE DISODIUM ANHYDROUS
NDC Codes#
| Product NDC | Package NDC |
|---|---|
| 45634-101 | 45634-101-01 |
Ingredients#
Every source-derived ingredient row is available through these pages.
Source Document#
openFDA label cross-check#
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| 8c488388-412a-403d-ac26-0f8910bebe38 | 0d709c0f-aacb-4f97-8f77-4fe924a58949 | 2022-02-10 | Warnings | 8c488388-412a-403d-ac26-0f8910bebe38 0d709c0f-aacb-4f97-8f77-4fe924a58949 |
Reported adverse events (FAERS/openFDA)#
Adverse event summaries are temporarily unavailable. Other product information remains available.

