FDA.reportPublic FDA data

Differin Daily Deep Cleanser with BPO

Manufacturer
Galderma Laboratories, L.P. | G Production Inc.
Effective date
2023-12-11
Label type
HUMAN OTC DRUG LABEL
Version
5
Source
full-release
Hydrated at
2026-06-01 00:04:18

Label at a glance#

ProductDifferin Daily Deep Cleanser with BPO
Active ingredientBenzoyl Peroxide
Label structure10 sections

Indications and uses

For the treatment of acne                 

Dosage and administration

■ Wet face. Gently massage all over face for about 20 – 30 seconds, avoiding the eye area. Rinse thoroughly and pat dry. ■ Because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor. ■ If bothersome dryness or peeling occurs, reduce application to once a day or every other day. ■ If going outside, apply ...

Label contents#

Full prescribing information#

Active Ingredients

OTC - ACTIVE INGREDIENT SECTION

 Benzoyl Peroxide 5% 

Purpose

OTC - PURPOSE SECTION

Acne treatment

Uses

INDICATIONS & USAGE SECTION

For the treatment of acne                 

Warnings

WARNINGS SECTION

For external use only.

When using this product
■ skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time. ■ avoid unnecessary sun exposure and use a sunscreen ■ avoid contact with the eyes, lips, and mouth ■ avoid contact with hair and dyed fabrics, which may be bleached by this product ■ skin irritation may occur, characterized by redness, burning, itching, peeling, or possibly swelling. Irritation may be reduced by using the product less frequently or in a lower concentration.

Do not use if you
■ Have very sensitive skin
■ Are sensitive to benzoyl peroxide

Stop use and ask a doctor if
■ Irritation becomes severe

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

Keep out of reach of children.
If swallowed, get medical help or contact a Poison Control Center right away.

Directions

DOSAGE & ADMINISTRATION SECTION

■ Wet face. Gently massage all over face for about 20 – 30 seconds, avoiding the eye area. Rinse thoroughly and pat dry. ■ Because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor. ■ If bothersome dryness or peeling occurs, reduce application to once a day or every other day. ■ If going outside, apply sunscreen after using this product. If irritation or sensitivity develops, stop use of both products and ask a doctor.

Inactive Ingredients

INACTIVE INGREDIENT SECTION

Carbomer, Glycerin, Lauryl Methacrylate/Glycol Dimethacrylate Crosspolymer, Sodium C14-16 Olefin Sulfonate, Sodium Hydroxide, Water

Questions or comments?

OTC - QUESTIONS SECTION

1-866-735-4137

OTC - QUESTIONS SECTION

Distributed by:

Galderma Laboratories, L.P.

Dallas, TX 75201
USA

All trademarks are the property of their respective owners

Made in Canada

www.differin.com

Principle Display Panel - 4 FL OZ carton

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

051803-P56842-1-Differin-Daily-Deep-Cleanser-4oz-Carton
051803-P56842-1-Differin-Daily-Deep-Cleanser-4oz-Carton

5%
Benzoyl
Peroxide

DIFFERIN®                 

CLEANSE

Daily
DEEP CLEANSER
Benzoyl Peroxide 5%
Acne Treatment

Treats acne and
helps prevent future
breakouts

Oil-absorbing

Formulated for
sensitive skin

4 FL OZ (118 mL)

P56842-1


DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYSPL version
308696benzoyl peroxide 5 % Medicated Liquid SoapPSN5
308696benzoyl peroxide 50 MG/ML Medicated Liquid SoapSCD5
308696benzoyl peroxide 5 % Medicated Liquid SoapSY5

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
a46239a7-5963-4008-8cbb-6b9000f497ebProduct name120250721
b382b4e1-6b48-45f6-bffc-e61b00b0ce19Product name320250317
d9d61457-6a5a-41fc-b418-e5479a2904b7Product name220230303
32012d5c-25ac-49c7-9d4c-1313177fff7cProduct name120230112
13e7e7e3-e885-4c79-af6d-dad1aedbb06eProduct name120220128
4a7d44fe-774d-404b-aad0-8a90fe78375aProduct name420211025
3f45980c-c196-47e5-0e5e-48b7c57327c5Product name520200428
d12e2d7c-bd6b-45d4-94f9-6df8e1b8b27bProduct name320200203
ee5c6de5-d9cd-454f-b250-7b19e5cf2992Product name420190619
ad75fcfd-a339-42a1-9c60-43ba2c654cfaProduct name120170810

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0299-4606-00Differin Daily Deep Cleanser with BPO118 mL in 1 TUBESOLUTION1185
0299-4606-00Differin Daily Deep Cleanser with BPO1 in 1 BOXSOLUTION15

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0299-4606DIFFERIN DAILY DEEP CLEANSER WITH BPO (BENZOYL PEROXIDE) SOLUTION [GALDERMA LABORATORIES, L.P.]5Current NDC, Legacy NDC, 2 package rows20231215_192b231b-51f1-457c-9a82-ef75671c0d34.zip

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0299-4606-00ML - Milliliter0299-4606f3f49790-7b27-492d-8f32-ffe7831d10c112022-04-06

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 8 matching rows.

NDC Codes#

Product NDC, Package NDC table
Product NDCPackage NDC
0299-46060299-4606-00

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 7 matching rows.

Name, UNII, Kind table
NameUNIIKind
Benzoyl PeroxideW9WZN9A0GMACTIB
Carboxypolymethylene0A5MM307FCIACT
Lauryl Methacrylate/glycol Dimethacrylate CrosspolymerEX0F4CZ66HIACT
Sodium C14-16 Olefin SulfonateO9W3D3YF5UIACT
Sodium Hydroxide55X04QC32IIACT
Water059QF0KO0RIACT
GlycerinPDC6A3C0OXIACT

Source Document#

Source XML

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Differin Daily Deep Cleanser with BPOBENZOYL PEROXIDEGalderma Laboratories, L.P.192b231b-51f1-457c-9a82-ef75671c0d342023-12-11WarningsExact identifier
ndc (package): 0299-4606-00
ndc (product): 0299-4606
ndc11 (package): 00299460600
spl id: 24a54860-8467-4a81-85c7-2d07b17be1fc
spl set id: 192b231b-51f1-457c-9a82-ef75671c0d34

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.