FDA.reportPublic FDA data

good sense pain relief

Manufacturer
ASCLEMED USA INC. | ASCLEMED USA INC. DBA ENOVACHEM
Effective date
2025-06-27
Label type
HUMAN OTC DRUG LABEL
Version
1
Source
full-release
Hydrated at
2026-06-01 01:06:11

Label at a glance#

Productgood sense pain relief arthritis pain
Active ingredientACETAMINOPHEN
Label structure10 sections

Indications and uses

• temporarily relieves minor aches and pains due to: • minor pain of arthritis • muscular aches • backache • premenstrual and menstrual cramps • the common cold • headache • toothache • temporarily reduces fever

Dosage and administration

• do not take more than directed (see overdose warning) adults •take 2 caplets every 8 hours with water •swallow whole; do not crush, chew, split or dissolve •do not take more than 6 caplets in 24 hours •do not use for more than 10 days unless directed by a doctor under 18 years of age •ask a doctor

Storage and handling

•store at 20-25°C (68-77°F) • do not use if printed foil under cap is broken or missing •meets the requirements of USP Dissolution Test 4

Label contents#

Full prescribing information#

Active ingredient (in each caplet)

OTC - ACTIVE INGREDIENT SECTION

Acetaminophen 650 mg

Purpose

OTC - PURPOSE SECTION

Pain reliever/fever reducer

Uses

INDICATIONS & USAGE SECTION

• temporarily relieves minor aches and pains due to:
• minor pain of arthritis
• muscular aches
• backache
• premenstrual and menstrual cramps
• the common cold
• headache
• toothache
• temporarily reduces fever

Warnings

WARNINGS SECTION

Liver warning:This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 6 caplets in 24 hours, which is the maximum daily amount
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert:Acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

OTC - DO NOT USE SECTION

• with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
• if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have

OTC - ASK DOCTOR SECTION

liver disease

Ask a doctor or pharmacist before use if you are

OTC - ASK DOCTOR/PHARMACIST SECTION

taking the blood thinning drug warfarin

Stop use and ask a doctor if

OTC - STOP USE SECTION

• pain gets worse or lasts more than 10 days
• fever gets worse or lasts more than 3 days
• new symptoms occur
• redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding,

OTC - PREGNANCY OR BREAST FEEDING SECTION

ask a health professional before use.

Keep out of reach of children.

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

Overdose warning:In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Directions

DOSAGE & ADMINISTRATION SECTION

• do not take more than directed (see overdose warning)

adults

•take 2 caplets every 8 hours with water

•swallow whole; do not crush, chew, split or dissolve

•do not take more than 6 caplets in 24 hours

•do not use for more than 10 days unless directed by a doctor

under 18 years of age

•ask a doctor

Other information

STORAGE AND HANDLING SECTION

•store at 20-25°C (68-77°F)

• do not use if printed foil under cap is broken or missing

•meets the requirements of USP Dissolution Test 4

Inactive ingredients

INACTIVE INGREDIENT SECTION

carnauba wax, colloidal silicon dioxide, croscarmellose sodium, hypromellose, magnesium stearate, maltodextrin, microcrystalline cellulose, polyethylene glycol, polysorbate 80, povidone, pregelatinized starch, stearic acid, titanium dioxide

Questions or comments?

OTC - QUESTIONS SECTION

1-800-719-9260

SPL UNCLASSIFIED SECTION

Relabeled and Repackaged by:

Enovachem PHARMACEUTICALS

Torrance, CA 90501

Principal Display Panel

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

labellabel

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYSPL version
1148399acetaminophen 650 MG 8HR Extended Release Oral TabletPSN1
11483998 HR acetaminophen 650 MG Extended Release Oral TabletSCD1
11483998 HR APAP 650 MG Extended Release Oral TabletSY1
1148399acetaminophen 650 MG 8 HR Extended Release Oral TabletSY1

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
75d4bef7-334c-4a95-abb5-bff9def24114Product name220260112
7dea7767-9f52-b60a-5435-33cb9cc28baeProduct name420250124
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11939cf5-0ea7-5df5-5127-00a7ce07fd7fProduct name520250115
0ca83774-3f79-b837-5d6f-c210102f3bc8Product name620250114
88300afc-e1c4-ad17-c80b-4957f1b809a5Product name520250113
4eddd6ca-259a-4c6c-a3a4-2025015ce043Product name720240611
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20ab58de-c64a-4ec2-9210-3aa3fae2b66fProduct name120230808
a3631b20-02d1-41d7-8187-5e5e850b9e80Product name120230306
79e1734e-f721-4d46-978a-be382f771672Product name220230110
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a590be26-846c-8659-a5a1-fb25907965dcProduct name220221110
06cc817f-60e0-4473-8e6b-c44d11dc5af6Product name920220921
92ead9ae-674d-4eee-a492-c385d496891fProduct name320220308
103b151b-b17f-42ac-8624-3ef62f5e2975Product name220200507
b8497372-efe9-9dde-fa2d-59be9761aa64Product name920200428
20c8cafe-5cfc-44f8-a9be-a664f437f780Product name220200225
3a16d77a-e865-468a-aedf-6e58913c1c21Product name320190619
2a0c98e1-033f-4e0d-a0da-b5291ffbe880Product name120190320
00d531e4-b130-8c52-eaf9-826cbb6f15ddProduct name320190205
aa0f353d-f35e-62e4-4e1f-5b563f01c659Product name920190205
22d922aa-c443-d9f3-b23c-03b03a9ad31cProduct name720181220
377068df-225f-7318-a910-a1987cdfa361Product name320170608
23475c0b-a5b5-4fec-b97f-acca901eae6aProduct name120140718
105ef617-6fa4-6713-326f-72ec8a6b75a9Product name120140508
332e86c3-7875-ca6e-f934-2206d2b31996Product name120140508
3ed6b849-48b8-8899-c288-6eeb396123b6Product name120140508
47fd879b-91c5-e1e5-130f-29d082a871ecProduct name120140508
53855190-7124-8179-f018-e792f7c27f28Product name120140508
7dfac40f-a405-cd2e-7c06-3059ec0e1092Product name120140508
84fb0b3d-1d72-b672-bc70-2b676a23e7e0Product name120140508
96c5169b-5b9d-547d-bf22-d688d91866e4Product name120140508
b8e0daf1-fb81-290b-c0bf-873be19ef775Product name120140508
c35d1ac8-8885-2ee1-6c52-5a715b242c00Product name120140508
c8753a88-edde-8e17-a396-705537b52ceeProduct name120140508
cd4f9ae2-1343-ecd2-ce0f-97db0c2b51ceProduct name120140508
cf3a804d-0326-aa22-0142-c184b5657d85Product name120140508
d83c592c-dd97-4cbf-36ac-13da806684bdProduct name120140508
e01133ad-4dcd-c7f3-454b-2ff569ee160aProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
76420-590-01good sense pain reliefarthritis pain100 in 1 BOTTLETABLET, FILM COATED, EXTENDED RE1001
76420-590-01good sense pain reliefarthritis pain1 in 1 CARTONTABLET, FILM COATED, EXTENDED RE11
76420-590-30good sense pain reliefarthritis pain30 in 1 BOTTLETABLET, FILM COATED, EXTENDED RE301
76420-590-60good sense pain reliefarthritis pain60 in 1 BOTTLETABLET, FILM COATED, EXTENDED RE601
76420-590-90good sense pain reliefarthritis pain90 in 1 BOTTLETABLET, FILM COATED, EXTENDED RE901

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
76420-590-01EA - Each76420-5905e42bc9b-c713-4b62-8090-03c0aa6365d012025-09-12
76420-590-30EA - Each76420-590910167cd-f4ea-4fa7-b695-cca79727171012025-09-12
76420-590-60EA - Each76420-59063f01b6b-4ad5-4961-a1aa-fcb73d0f2e6d12025-09-12
76420-590-90EA - Each76420-590c07f7ff5-c829-4802-b408-8b14c46d785912025-09-12
0113-0544-62EA - Each0113-05440ed9b51c-5183-4d3c-98bc-b4d389e1dd8a12012-07-24
0113-0544-71EA - Each0113-0544303a473a-8f68-401c-9d71-7a56f2356fcd12012-07-24
0113-0544-78EA - Each0113-0544c7c587b2-5823-4d0b-93f9-32cc106c609312016-09-02

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 14 matching rows.

NDC Codes#

Product NDC, Package NDC table
Product NDCPackage NDC
76420-59076420-590-01, 76420-590-30, 76420-590-60, 76420-590-90
0113-0544

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 13 matching rows.

Name, UNII, Kind table
NameUNIIKind
CARNAUBA WAXR12CBM0EIZIACT
SILICON DIOXIDEETJ7Z6XBU4IACT
CROSCARMELLOSE SODIUMM28OL1HH48IACT
HYPROMELLOSE, UNSPECIFIED3NXW29V3WOIACT
MAGNESIUM STEARATE70097M6I30IACT
MALTODEXTRIN7CVR7L4A2DIACT
MICROCRYSTALLINE CELLULOSEOP1R32D61UIACT
POLYETHYLENE GLYCOL, UNSPECIFIED3WJQ0SDW1AIACT
POLYSORBATE 806OZP39ZG8HIACT
POVIDONE, UNSPECIFIEDFZ989GH94EIACT
STEARIC ACID4ELV7Z65APIACT
TITANIUM DIOXIDE15FIX9V2JPIACT
ACETAMINOPHEN362O9ITL9DACTIB

Source Document#

Source XML

Orange Book application contexts#

All distinct exact application/product contexts derived from this label’s complete NDC list are paginated below.

Orange Book application contexts page 1 of 1 · 1 matching rows.

Source provenance: Browse the complete Orange Book source catalog · source snapshot 43.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A075077-001ACETAMINOPHENACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-25

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 43 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-09-14 22:38:342026-08A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-2584e616aacf4f…
2026-08-18 06:07:402026-07A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-25caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-25011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-2531067a03dcf5…
2025-08-23 18:47 UTC2025-08A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-256a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-25fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-25b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-2503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-252680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-255bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-25d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-25d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-2579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-25301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-251e350fbaab3a…
2024-05-31 18:47 UTC2024-05A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-258072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-255c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-255d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-254b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-2574a2ff9319b5…
2022-03-09 01:35 UTC2022-03A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-25bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-25782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-2587673890dc5c…
2021-03-12 10:30 UTC2021-03A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-255aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-258869cabd3fbd…
2020-11-12 02:37 UTC2020-11A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-25c0c555d07b60…
2019-12-14 00:12 UTC2019-12A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-253f01610625f2…
2019-09-15 20:21 UTC2019-09A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-25b00525d2431f…
2019-07-19 19:46 UTC2019-07A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-25ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-256a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-251c564ffb4f44…
2023-12-20 04:57 UTC2023-12A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-25ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-25a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-259b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-25a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-253f0d92c62455…
2023-05-13 08:27 UTC2023-05A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-25053a50430f4f…
2023-01-26 05:58 UTC2023-01A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-253bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-253a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A075077-001ACETAMINOPHEN650MGTABLET, EXTENDED RELEASE / ORAL2000-02-25f41ea6bd6efb…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
good sense pain relief arthritis painACETAMINOPHENL. Perrigo Company236eedd4-6ece-46ce-9ab3-12366d57126b2026-02-09WarningsExact identifier
ndc (product): 0113-0544
good sense pain relief arthritis painACETAMINOPHENASCLEMED USA INC.2315ec07-e5b8-4332-8bc2-4e28e88892f32025-06-27WarningsExact identifier
ndc (package): 76420-590-30
ndc (package): 76420-590-60
ndc (package): 76420-590-90
ndc (package): 76420-590-01
ndc (product): 76420-590
ndc11 (package): 76420059030
ndc11 (package): 76420059090
ndc11 (package): 76420059001
ndc11 (package): 76420059060
spl id: 3886c8f2-b1c3-4da9-e063-6394a90a956e
spl set id: 2315ec07-e5b8-4332-8bc2-4e28e88892f3

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.