FDA.reportPublic FDA data

Up and Up 4CA81001

Manufacturer
Target Corporation | Nice-Pak Products, LLC
Effective date
2026-09-03
Label type
HUMAN OTC DRUG LABEL
Version
12
Source
daily-update
Hydrated at
2026-09-08 02:01:46

Label at a glance#

Productup and up medicated wipes manixim strength
Active ingredientWITCH HAZEL
Label structure14 sections

Indications and uses

helps relieve the local itching and discomfort associated with hemorrhoids temporary relief of irritation and burning aids in protecting irritated anorectal areas

Dosage and administration

adult: unfold wipe and cleanse the area by gently wiping, patting or blotting. If necessary, repeat until all matter is removed from the area. Use up to 6 times daily or after each bowel movement and before applying topical hemorrhoidal treatments, and then discard children under 12 years of age: consult a doctor

Label contents#

Full prescribing information#

Active ingredient

OTC - ACTIVE INGREDIENT SECTION

Witch hazel 50%

Purpose

OTC - PURPOSE SECTION

Astringent

Uses

INDICATIONS & USAGE SECTION

  • helps relieve the local itching and discomfort associated with hemorrhoids
  • temporary relief of irritation and burning
  • aids in protecting irritated anorectal areas

Warnings

WARNINGS SECTION

For external use only

When using this product

OTC - WHEN USING SECTION

  • do not exceed the recommended daily dosage unless directed by a doctor
  • do not put this product into the rectum by using fingers or any mechanical device or applicator

Stop use and ask a doctor if

OTC - STOP USE SECTION

  • bleeding occurs
  • condition worsens or does not improve within 7 days

Keep out of reach of children.

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

If swallowed, get medical help or contact a Poison Control Center right away.(1-800-222-1222)

Directions

DOSAGE & ADMINISTRATION SECTION

  • adult: unfold wipe and cleanse the area by gently wiping, patting or blotting. If necessary, repeat until all matter is removed from the area.
  • Use up to 6 times daily or after each bowel movement and before applying topical hemorrhoidal treatments, and then discard
  • children under 12 years of age: consult a doctor

Other information

OTHER SAFETY INFORMATION

store at room temperature 20-25ºC (68-77ºF)

Inactive ingredients

INACTIVE INGREDIENT SECTION

2-Bromo-2-Nitropropane-1,3-Diol, Aloe Barbadensis Leaf Juice, Citric Acid, Disodium Cocoamphodiacetate, Glycerin, Iodopropynyl Butylcarbamate, PEG-75 Lanolin, Propylene Glycol, Sodium Citrate, Water

Other Uses:

SPL UNCLASSIFIED SECTION

For external vaginal care - cleanse the area by gently wiping, patting, or blotting. Repeat as needed.

For use as a moist compress - first cleanse the area. Fold wipe to desired size and place in contact with tissue for a soothing and cooling effect. Leave in place for 15 minutes and repeat as needed.

Adverse Reaction

ADVERSE REACTIONS SECTION

Distributed by Target Corporation

Minneapolis, MN 55403

Made in USA of domestic and imported materials

Satisfaction guaranteed - Love it or your money back.

We welcome any questions you may have at Target.com/comments or 1-800-910-6874.

Disclaimers

SPL UNCLASSIFIED SECTION

*This product in not manufactured or distributed by GlaxoSmithKline Consumer Healthcare Holdings (US) LLC, owner of the registered trademark Preparation H  ®.

**Not recommended for usw with basement pump systems. Flush only one wipe at a time. Keep lid closed when not in use.

Principal display panel

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

Compare to active ingredient in Preparation H  ®Medicated Wipes*

Maximum Strength

Hemmorrhoidal Wipes

Gentle Hemorrhoidal Care

  • with witch hazel and aloe to cool
  • No fragrance added

up & up™

FLUSHABLE

48 Count

48 MEDICATED WIPES

6 in x 5 in (15.2cm x 12.7 cm)

image descriptionimage description

image descriptionimage description

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
e2db08c6-133f-4f4f-afb4-e90a2418d6f6Product name120230320
ce6d5c06-3ae0-18a6-d5b3-8cd3cc0f8906Product name720210625
f52be47f-7aa7-46c0-b1fa-50c18dd50206Product name120201029
11ed6f83-cdd2-4637-8379-b1a1d3ae3cdeProduct name120181101
86c45a79-b9f0-4476-a27c-6e10db098497Product name120180125
d5e51f11-ad28-caa4-4b49-4143974782adProduct name120150831

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 13 matching rows.

NDC Codes#

Product NDC, Package NDC table
Product NDCPackage NDC
11673-40411673-404-96, 11673-404-48

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 11 matching rows.

Name, UNII, Kind table
NameUNIIKind
WITCH HAZEL101I4J0U34ACTIB
ANHYDROUS CITRIC ACIDXF417D3PSLIACT
PROPYLENE GLYCOL6DC9Q167V3IACT
SODIUM CITRATE1Q73Q2JULRIACT
BRONOPOL6PU1E16C9WIACT
GLYCERINPDC6A3C0OXIACT
ALOE VERA LEAFZY81Z83H0XIACT
DISODIUM COCOAMPHODIACETATE18L9G3U51MIACT
IODOPROPYNYL BUTYLCARBAMATE603P14DHEBIACT
PEG-75 LANOLIN09179OX7TBIACT
WATER059QF0KO0RIACT

Source Document#

Source XML

Older Hydrated Versions#

Version, Effective date, Source table
VersionEffective dateSourceHydrated
102024-11-07full-release2026-06-01 00:35:31

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
up and up medicated wipes manixim strengthGENTLE HEMORRHOIDAL CARETarget Corporation271eab2b-ed13-39f1-e054-00144ff88e882026-09-03Warnings, Adverse reactionsExact identifier
ndc (package): 11673-404-96
ndc (package): 11673-404-48
ndc (product): 11673-404
ndc11 (package): 11673040448
ndc11 (package): 11673040496
spl id: 5a97c116-a67b-d23d-e063-6294a90a9468
spl set id: 271eab2b-ed13-39f1-e054-00144ff88e88

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.