Acne Treatment

Manufacturer: Natureplex, LLC
Effective date: 2026-01-29
Label type: HUMAN OTC DRUG LABEL
Version: 4
Source: full-release
Hydrated at: 2026-06-01 01:35:23

Label at a glance#

ProductAcne Treatment

Active ingredientSALICYLIC ACID

Label structure10 sections

Dosage and administration

Sensitivity Test for a New User. Apply product sparingly to one or two small affected areas during the first 3 days. If no discomfort occurs, follow the directions stated below clean the skin thoroughly before applying this product cover entire affected area with a thin layer 1 to 3 times daily because excessive drying of skin may occur, start with one application daily, and gradually increase to 2 or 3 times dail...

Storage and handling

store at 15 to 30°C (59 to 86°F) close cap tightly after use Tamper Evident: DO NOT USE IF SEAL ON TUBE IS BROKEN OR MISSING.

Contacts and useful links#

PhonePoison Help800-222-1222

PhoneLabel contact866-323-0107

Websitewww.natureplex.com

www.natureplex.com

Label contents#

Full prescribing information#

SPL UNCLASSIFIED SECTION

Drug Facts

Active ingredient

OTC - ACTIVE INGREDIENT SECTION

Salicylic Acid 0.5%

Purpose

OTC - PURPOSE SECTION

Acne Treatment

Use

INDICATIONS & USAGE SECTION

For the treatment of acne.

Warnings

WARNINGS SECTION

For external use only.

When using this product

OTC - WHEN USING SECTION

skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.

OTC - PREGNANCY OR BREAST FEEDING SECTION

If pregnant or breast-feeding, ask a health professional before use.

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away: 800-222-1222.

Directions

DOSAGE & ADMINISTRATION SECTION

Sensitivity Test for a New User. Apply product sparingly to one or two small affected areas during the first 3 days. If no discomfort occurs, follow the directions stated below
clean the skin thoroughly before applying this product
cover entire affected area with a thin layer 1 to 3 times daily
because excessive drying of skin may occur, start with one application daily, and gradually increase to 2 or 3 times daily if needed or as directed by a doctor
if bothersome dryness or peeling occurs, reduce application to once a day or every other day

Other information

STORAGE AND HANDLING SECTION

store at 15 to 30°C (59 to 86°F)
close cap tightly after use
Tamper Evident: DO NOT USE IF SEAL ON TUBE IS BROKEN OR MISSING.

Inactive ingredients

INACTIVE INGREDIENT SECTION

citric acid, sodium phosphate dibasic, DMDM hydantoin, glycerin, hydroxyethylcellulose, isopropyl alcohol, methylparaben, polysorbate-20, propylene glycol, propylparaben, purified water

Questions or comments?

OTC - QUESTIONS SECTION

866-323-0107 or www.natureplex.com

PRINCIPAL DISPLAY PANEL - 42.5 g Tube Box

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

Natureplex™

Acne
Treatment
Clear Gel

NET WT. 1.5 Oz.(42.5g)

Principal Display Panel - 42.5 g Tube Box

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	SPL version
252296	salicylic acid 0.5 % Topical Gel	PSN	4
252296	salicylic acid 0.005 MG/MG Topical Gel	SCD	4
252296	salicylic acid 0.5 % Topical Gel	SY	4

Product Linked Resources#

Resource, Code type, Value table
Resource	Code type	Value	Equivalent identifiers	Source image
QR code link	QR Code	www.natureplex.com/product-pages/acne.html		acne-treatment-01.jpg

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
dea2eded-d1e7-46bb-9a3d-f8dc20de6277	Product name	1	20190408

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDC	Effective	Action	Document	Indexing SPL	Related label
67234-007-01	2025-01-30	C162847	48780-1	2cef2736-8653-d83d-e063-dadaa90ab31f	Acne Treatment

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
67234-007-01	Acne Treatment	42 g in 1 TUBE	GEL	42		4
67234-007-01	Acne Treatment	1 in 1 BOX	GEL	1		4

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	SPL version
SALICYLIC ACID	ACTIVE INGREDIENT	O414PZ4LPZ	1
SALICYLIC ACID	ACTIVE MOIETY	O414PZ4LPZ	1
DMDM HYDANTOIN	INACTIVE INGREDIENT	BYR0546TOW	1
GLYCERIN	INACTIVE INGREDIENT	PDC6A3C0OX	1
HYDROXYETHYL CELLULOSE (1500 MPA.S AT 1%)	INACTIVE INGREDIENT	L605B5892V	1
METHYLPARABEN	INACTIVE INGREDIENT	A2I8C7HI9T	1
PROPYLENE GLYCOL	INACTIVE INGREDIENT	6DC9Q167V3	1
PROPYLPARABEN	INACTIVE INGREDIENT	Z8IX2SC1OH	1
WATER	INACTIVE INGREDIENT	059QF0KO0R	1

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 9 matching rows.

Acne Treatment
SALICYLIC ACID
DMDM HYDANTOIN
GLYCERIN
HYDROXYETHYL CELLULOSE (1500 MPA.S AT 1%)
METHYLPARABEN
PROPYLPARABEN
PROPYLENE GLYCOL
WATER

NDC Codes#

Product NDC, Package NDC table
Product NDC	Package NDC
67234-007	67234-007-01

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 8 matching rows.

Name, UNII, Kind table
Name	UNII	Kind
SALICYLIC ACID	O414PZ4LPZ	ACTIB
DMDM HYDANTOIN	BYR0546TOW	IACT
GLYCERIN	PDC6A3C0OX	IACT
HYDROXYETHYL CELLULOSE (1500 MPA.S AT 1%)	L605B5892V	IACT
METHYLPARABEN	A2I8C7HI9T	IACT
PROPYLPARABEN	Z8IX2SC1OH	IACT
PROPYLENE GLYCOL	6DC9Q167V3	IACT
WATER	059QF0KO0R	IACT

Source Document#

Source XML

Inactive ingredient matches#

Inactive Ingredient Database values describe FDA-listed use contexts. The match method and ambiguity count are shown because ingredient names, routes, and dosage forms are not always unique. Browse recovered IID releases and source provenance.

Inactive ingredient links page 1 of 1 · 10 matching rows.

DailyMed ingredient, IID ingredient, UNII table
DailyMed ingredient	IID ingredient	UNII	Dosage form / route	Maximum daily exposure	Match
GLYCERIN	GLYCERIN	PDC6A3C0OX	GEL / TOPICAL	500 mg	Exact identifier — unii+route+dosage form 2 equally ranked IID candidates
PROPYLPARABEN	PROPYLPARABEN	Z8IX2SC1OH	GEL / TOPICAL	4 mg	Exact identifier — unii+route+dosage form 2 equally ranked IID candidates
DMDM HYDANTOIN	DMDM HYDANTOIN	BYR0546TOW	LOTION / TOPICAL	3 mg	Exact identifier — unii+route 2 equally ranked IID candidates
PROPYLENE GLYCOL	PROPYLENE GLYCOL	6DC9Q167V3	GEL / TOPICAL	4522 mg	Exact identifier — unii+route+dosage form 2 equally ranked IID candidates
PROPYLPARABEN	PROPYLPARABEN	Z8IX2SC1OH	GEL / TOPICAL	4 mg	Exact identifier — unii+route+dosage form 2 equally ranked IID candidates
METHYLPARABEN	METHYLPARABEN	A2I8C7HI9T	GEL / TOPICAL	24 mg	Exact identifier — unii+route+dosage form 2 equally ranked IID candidates
DMDM HYDANTOIN	DMDM HYDANTOIN	BYR0546TOW	LOTION / TOPICAL	3 mg	Exact identifier — unii+route 2 equally ranked IID candidates
GLYCERIN	GLYCERIN	PDC6A3C0OX	GEL / TOPICAL	500 mg	Exact identifier — unii+route+dosage form 2 equally ranked IID candidates
METHYLPARABEN	METHYLPARABEN	A2I8C7HI9T	GEL / TOPICAL	24 mg	Exact identifier — unii+route+dosage form 2 equally ranked IID candidates
PROPYLENE GLYCOL	PROPYLENE GLYCOL	6DC9Q167V3	GEL / TOPICAL	4522 mg	Exact identifier — unii+route+dosage form 2 equally ranked IID candidates

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Acne Treatment	SALICYLIC ACID	Natureplex, LLC	31b50718-cc60-460d-aad7-b9620970d411	2026-01-29	Warnings	Exact identifier ndc (package): 67234-007-01 ndc (product): 67234-007 ndc11 (package): 67234000701 spl id: 1a6cc968-bb0b-438c-a780-cd96f466c28b spl set id: 31b50718-cc60-460d-aad7-b9620970d411

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.