National Council for Prescription Drug Programs indexing - billing unit

Manufacturer: National Council for Prescription Drug Programs
Effective date: 2012-07-24
Label type: Indexing - Billing Unit
Version: 1
Source: full-release
Hydrated at: 2026-06-05 01:26:08

Label at a glance#

RxCUI, Display, Full name table
RxCUI	Display	Full name	Type
1725046	MARCAINE (Injectable)	30 ML bupivacaine hydrochloride 5 MG/ML Injection [Marcaine]	SBD Active
1012404	BUPivacaine (Injectable)	bupivacaine hydrochloride 5 MG/ML Injectable Solution	SCD Active
1012406	MARCAINE (Injectable)	bupivacaine hydrochloride 5 MG/ML Injectable Solution [Marcaine]	SBD Active

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
0409-1560-29	ML - Milliliter	0409-1560	2d596c5c-df94-459f-ab85-48633ec02643	1	2012-07-24

NDC Codes#

Product NDC, Package NDC table
Product NDC	Package NDC
0409-1560	0409-1560-29

Source Document#

Source XML

Orange Book application contexts#

All distinct exact application/product contexts derived from this label’s complete NDC list are paginated below.

Orange Book application contexts page 1 of 1 · 1 matching rows.

Source provenance: Browse the complete Orange Book source catalog · source snapshot 44.

Orange Book products#

Current product rows page 1 of 1 · 10 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS
N016964-001	MARCAINE HYDROCHLORIDE	BUPIVACAINE HYDROCHLORIDE	0.25%	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982
N016964-004	MARCAINE HYDROCHLORIDE W/ EPINEPHRINE	BUPIVACAINE HYDROCHLORIDE; EPINEPHRINE BITARTRATE	0.25%;0.0091MG/ML	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982
N016964-005	MARCAINE HYDROCHLORIDE PRESERVATIVE FREE	BUPIVACAINE HYDROCHLORIDE	0.5%	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982
N016964-006	MARCAINE HYDROCHLORIDE	BUPIVACAINE HYDROCHLORIDE	0.5%	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982
N016964-007	MARCAINE HYDROCHLORIDE W/ EPINEPHRINE PRESERVATIVE FREE	BUPIVACAINE HYDROCHLORIDE; EPINEPHRINE BITARTRATE	0.5%;0.0091MG/ML	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982
N016964-008	MARCAINE HYDROCHLORIDE W/ EPINEPHRINE	BUPIVACAINE HYDROCHLORIDE; EPINEPHRINE BITARTRATE	0.5%;0.0091MG/ML	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982
N016964-009	MARCAINE HYDROCHLORIDE PRESERVATIVE FREE	BUPIVACAINE HYDROCHLORIDE	0.75%	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982
N016964-010	MARCAINE HYDROCHLORIDE W/ EPINEPHRINE PRESERVATIVE FREE	BUPIVACAINE HYDROCHLORIDE; EPINEPHRINE BITARTRATE	0.75%;0.0091MG/ML	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982
N016964-012	MARCAINE HYDROCHLORIDE PRESERVATIVE FREE	BUPIVACAINE HYDROCHLORIDE	0.25%	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982
N016964-013	MARCAINE HYDROCHLORIDE W/ EPINEPHRINE PRESERVATIVE FREE	BUPIVACAINE HYDROCHLORIDE; EPINEPHRINE BITARTRATE	0.25%;0.0091MG/ML	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 10 matching rows.

Application-product, TE code table
Application-product	TE code
N016964-001	AP
N016964-004	AP
N016964-005	AP
N016964-006	AP
N016964-007	AP
N016964-008	AP
N016964-009	AP
N016964-010	AP
N016964-012	AP
N016964-013	AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 11 · 440 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Product TE source text	RLD / RS	Source SHA-256
2026-10-15 13:18:30	2026-09	N016964-001	MARCAINE HYDROCHLORIDE	0.25%	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`c2088c7a36db…`
2026-10-15 13:18:30	2026-09	N016964-004	MARCAINE HYDROCHLORIDE W/ EPINEPHRINE	0.25%;0.0091MG/ML	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`c2088c7a36db…`
2026-10-15 13:18:30	2026-09	N016964-005	MARCAINE HYDROCHLORIDE PRESERVATIVE FREE	0.5%	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`c2088c7a36db…`
2026-10-15 13:18:30	2026-09	N016964-006	MARCAINE HYDROCHLORIDE	0.5%	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`c2088c7a36db…`
2026-10-15 13:18:30	2026-09	N016964-007	MARCAINE HYDROCHLORIDE W/ EPINEPHRINE PRESERVATIVE FREE	0.5%;0.0091MG/ML	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`c2088c7a36db…`
2026-10-15 13:18:30	2026-09	N016964-008	MARCAINE HYDROCHLORIDE W/ EPINEPHRINE	0.5%;0.0091MG/ML	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`c2088c7a36db…`
2026-10-15 13:18:30	2026-09	N016964-009	MARCAINE HYDROCHLORIDE PRESERVATIVE FREE	0.75%	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`c2088c7a36db…`
2026-10-15 13:18:30	2026-09	N016964-010	MARCAINE HYDROCHLORIDE W/ EPINEPHRINE PRESERVATIVE FREE	0.75%;0.0091MG/ML	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`c2088c7a36db…`
2026-10-15 13:18:30	2026-09	N016964-012	MARCAINE HYDROCHLORIDE PRESERVATIVE FREE	0.25%	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`c2088c7a36db…`
2026-10-15 13:18:30	2026-09	N016964-013	MARCAINE HYDROCHLORIDE W/ EPINEPHRINE PRESERVATIVE FREE	0.25%;0.0091MG/ML	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`c2088c7a36db…`
2026-09-14 22:38:34	2026-08	N016964-001	MARCAINE HYDROCHLORIDE	0.25%	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N016964-004	MARCAINE HYDROCHLORIDE W/ EPINEPHRINE	0.25%;0.0091MG/ML	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N016964-005	MARCAINE HYDROCHLORIDE PRESERVATIVE FREE	0.5%	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N016964-006	MARCAINE HYDROCHLORIDE	0.5%	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N016964-007	MARCAINE HYDROCHLORIDE W/ EPINEPHRINE PRESERVATIVE FREE	0.5%;0.0091MG/ML	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N016964-008	MARCAINE HYDROCHLORIDE W/ EPINEPHRINE	0.5%;0.0091MG/ML	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N016964-009	MARCAINE HYDROCHLORIDE PRESERVATIVE FREE	0.75%	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N016964-010	MARCAINE HYDROCHLORIDE W/ EPINEPHRINE PRESERVATIVE FREE	0.75%;0.0091MG/ML	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N016964-012	MARCAINE HYDROCHLORIDE PRESERVATIVE FREE	0.25%	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N016964-013	MARCAINE HYDROCHLORIDE W/ EPINEPHRINE PRESERVATIVE FREE	0.25%;0.0091MG/ML	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	N016964-001	MARCAINE HYDROCHLORIDE	0.25%	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N016964-004	MARCAINE HYDROCHLORIDE W/ EPINEPHRINE	0.25%;0.0091MG/ML	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N016964-005	MARCAINE HYDROCHLORIDE PRESERVATIVE FREE	0.5%	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N016964-006	MARCAINE HYDROCHLORIDE	0.5%	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N016964-007	MARCAINE HYDROCHLORIDE W/ EPINEPHRINE PRESERVATIVE FREE	0.5%;0.0091MG/ML	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N016964-008	MARCAINE HYDROCHLORIDE W/ EPINEPHRINE	0.5%;0.0091MG/ML	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N016964-009	MARCAINE HYDROCHLORIDE PRESERVATIVE FREE	0.75%	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N016964-010	MARCAINE HYDROCHLORIDE W/ EPINEPHRINE PRESERVATIVE FREE	0.75%;0.0091MG/ML	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N016964-012	MARCAINE HYDROCHLORIDE PRESERVATIVE FREE	0.25%	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N016964-013	MARCAINE HYDROCHLORIDE W/ EPINEPHRINE PRESERVATIVE FREE	0.25%;0.0091MG/ML	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	N016964-001	MARCAINE HYDROCHLORIDE	0.25%	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N016964-004	MARCAINE HYDROCHLORIDE W/ EPINEPHRINE	0.25%;0.0091MG/ML	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N016964-005	MARCAINE HYDROCHLORIDE PRESERVATIVE FREE	0.5%	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N016964-006	MARCAINE HYDROCHLORIDE	0.5%	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N016964-007	MARCAINE HYDROCHLORIDE W/ EPINEPHRINE PRESERVATIVE FREE	0.5%;0.0091MG/ML	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N016964-008	MARCAINE HYDROCHLORIDE W/ EPINEPHRINE	0.5%;0.0091MG/ML	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N016964-009	MARCAINE HYDROCHLORIDE PRESERVATIVE FREE	0.75%	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N016964-010	MARCAINE HYDROCHLORIDE W/ EPINEPHRINE PRESERVATIVE FREE	0.75%;0.0091MG/ML	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N016964-012	MARCAINE HYDROCHLORIDE PRESERVATIVE FREE	0.25%	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N016964-013	MARCAINE HYDROCHLORIDE W/ EPINEPHRINE PRESERVATIVE FREE	0.25%;0.0091MG/ML	INJECTABLE / INJECTION	AP	RLD, RS, Approved before 1982	`011fe1cb6892…`

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 11 · 440 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	TE code	Order	Source SHA-256
2026-10-15 13:18:30	2026-09	N016964-001	AP	1	`c2088c7a36db…`
2026-10-15 13:18:30	2026-09	N016964-004	AP	1	`c2088c7a36db…`
2026-10-15 13:18:30	2026-09	N016964-005	AP	1	`c2088c7a36db…`
2026-10-15 13:18:30	2026-09	N016964-006	AP	1	`c2088c7a36db…`
2026-10-15 13:18:30	2026-09	N016964-007	AP	1	`c2088c7a36db…`
2026-10-15 13:18:30	2026-09	N016964-008	AP	1	`c2088c7a36db…`
2026-10-15 13:18:30	2026-09	N016964-009	AP	1	`c2088c7a36db…`
2026-10-15 13:18:30	2026-09	N016964-010	AP	1	`c2088c7a36db…`
2026-10-15 13:18:30	2026-09	N016964-012	AP	1	`c2088c7a36db…`
2026-10-15 13:18:30	2026-09	N016964-013	AP	1	`c2088c7a36db…`
2026-09-14 22:38:34	2026-08	N016964-001	AP	1	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N016964-004	AP	1	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N016964-005	AP	1	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N016964-006	AP	1	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N016964-007	AP	1	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N016964-008	AP	1	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N016964-009	AP	1	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N016964-010	AP	1	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N016964-012	AP	1	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N016964-013	AP	1	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	N016964-001	AP	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N016964-004	AP	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N016964-005	AP	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N016964-006	AP	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N016964-007	AP	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N016964-008	AP	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N016964-009	AP	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N016964-010	AP	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N016964-012	AP	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N016964-013	AP	1	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	N016964-001	AP	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N016964-004	AP	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N016964-005	AP	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N016964-006	AP	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N016964-007	AP	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N016964-008	AP	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N016964-009	AP	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N016964-010	AP	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N016964-012	AP	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N016964-013	AP	1	`011fe1cb6892…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.