FDA.reportPublic FDA data

Head and Shoulders Conditioner

Manufacturer
The Procter & Gamble Manufacturing Company
Effective date
2025-12-18
Label type
HUMAN OTC DRUG LABEL
Version
12
Source
full-release
Hydrated at
2026-06-01 01:26:17

Label at a glance#

ProductHead and Shoulders Conditioner Smooth and Silky
Active ingredientPYRITHIONE ZINC
Label structure10 sections

Indications and uses

helps prevent recurrence of flaking and itching associated with dandruff.

Dosage and administration

for best results use at least twice a week or as directed by a doctor. apply to wet hair after shampooing by gently massaging into hair and scalp, rinse well.

Label contents#

Full prescribing information#

SPL UNCLASSIFIED SECTION

Drug Facts

Active ingredient

OTC - ACTIVE INGREDIENT SECTION

Pyrithione zinc 0.5%

Purpose

OTC - PURPOSE SECTION

Anti-dandruff

Uses

INDICATIONS & USAGE SECTION

helps prevent recurrence of flaking and itching associated with dandruff.

Warnings

WARNINGS SECTION

SPL UNCLASSIFIED SECTION

For external use only.

OTC - WHEN USING SECTION

When using this product

  • avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water.

OTC - STOP USE SECTION

Stop use and ask a doctor if

  • condition worsens or does not improve after regular use of this product as directed.

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

Keep this and all drugs out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Directions

DOSAGE & ADMINISTRATION SECTION

  • for best results use at least twice a week or as directed by a doctor.
  • apply to wet hair after shampooing by gently massaging into hair and scalp, rinse well.

Inactive ingredients

INACTIVE INGREDIENT SECTION

Water, stearyl alcohol, cetyl alcohol, stearamidopropyl dimethylamine, glutamic acid, dimethicone, fragrance, phenoxyethanol, benzyl alcohol, citric acid, sodium chloride, methylchloroisothiazolinone, methylisothiazolinone.

Questions (or comments)?

OTC - QUESTIONS SECTION

1-800-723-9569

SPL UNCLASSIFIED SECTION

Dist. by PROCTER & GAMBLE,
CINCINNATI, OH 45202

PRINCIPAL DISPLAY PANEL - 315 mL Tube Label

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

head &

shoulders ®

pyrithione zinc dandruff conditioner

smooth & silky
HAIR & SCALP
CONDITIONER

24 hour frizz control from root to tip

10.6 FL OZ (315 mL)

HSHS

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYSPL version
1044465head & shoulders 0.5 % Medicated ShampooPSN12
1043014zinc pyrithione 0.5 % Medicated ConditionerPSN12
1044465zinc pyrithione 5 MG/ML Medicated Shampoo [Head & Shoulders]SBD12
1043014zinc pyrithione 5 MG/ML Medicated ShampooSCD12
1044465Head & Shoulders 0.5 % ConditionerSY12
1044465Head & Shoulders 5 MG/ML Medicated ShampooSY12
1043014zinc pyrithione 0.5 % Medicated ShampooSY12

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
0ca1d589-929b-4b33-bc5b-1d84abdafa6aProduct name120150324
fc363c46-397b-4476-ac0f-70e43e8e4592Product name120150324
9869efd7-d6dd-0665-5b67-53adbe6ef15eProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
69423-103-10Head and Shoulders ConditionerSmooth and Silky10 mL in 1 POUCHLOTION1012
69423-103-25Head and Shoulders ConditionerSmooth and Silky250 mL in 1 BOTTLE, PLASTICLOTION25012
69423-103-31Head and Shoulders ConditionerSmooth and Silky315 mL in 1 TUBELOTION31512
69423-103-38Head and Shoulders ConditionerSmooth and Silky380 mL in 1 BOTTLE, PLASTICLOTION38012
69423-103-40Head and Shoulders ConditionerSmooth and Silky400 mL in 1 BOTTLE, PLASTICLOTION40012
69423-103-59Head and Shoulders ConditionerSmooth and Silky592 mL in 1 BOTTLE, PLASTICLOTION59212
69423-103-61Head and Shoulders ConditionerSmooth and Silky610 mL in 1 BOTTLE, PLASTICLOTION61012
69423-103-65Head and Shoulders ConditionerSmooth and Silky650 mL in 1 BOTTLE, PLASTICLOTION65012
69423-103-68Head and Shoulders ConditionerSmooth and Silky680 mL in 1 BOTTLE, PLASTICLOTION68012
69423-103-90Head and Shoulders ConditionerSmooth and Silky90 mL in 1 BOTTLE, PLASTICLOTION9012

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 14 matching rows.

NDC Codes#

Product NDC, Package NDC table
Product NDCPackage NDC
69423-10369423-103-40, 69423-103-68, 69423-103-90, 69423-103-65, 69423-103-38, 69423-103-10, 69423-103-25, 69423-103-61, 69423-103-31, 69423-103-59

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 13 matching rows.

Name, UNII, Kind table
NameUNIIKind
STEARYL ALCOHOL2KR89I4H1YIACT
WATER059QF0KO0RIACT
CETYL ALCOHOL936JST6JCNIACT
STEARAMIDOPROPYL DIMETHYLAMINEK7VEI00UFRIACT
GLUTAMIC ACID3KX376GY7LIACT
DIMETHICONE92RU3N3Y1OIACT
PHENOXYETHANOLHIE492ZZ3TIACT
BENZYL ALCOHOLLKG8494WBHIACT
CITRIC ACID MONOHYDRATE2968PHW8QPIACT
SODIUM CHLORIDE451W47IQ8XIACT
METHYLCHLOROISOTHIAZOLINONEDEL7T5QRPNIACT
METHYLISOTHIAZOLINONE229D0E1QFAIACT
PYRITHIONE ZINCR953O2RHZ5ACTIB

Source Document#

Source XML

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Head and Shoulders Dual Pack Smooth and SilkyPYRITHIONE ZINCThe Procter & Gamble Manufacturing Company19ad72ea-9a4b-0a35-e063-6394a90a91312025-12-31WarningsExact identifier
ndc (package): 69423-103-31
ndc11 (package): 69423010331
Head and Shoulders Conditioner Smooth and SilkyPYRITHIONE ZINCThe Procter & Gamble Manufacturing Company41709710-539c-3119-e054-00144ff88e882025-12-18WarningsExact identifier
ndc (package): 69423-103-10
ndc (package): 69423-103-59
ndc (package): 69423-103-65
ndc (package): 69423-103-25
ndc (package): 69423-103-68
ndc (package): 69423-103-90
ndc (package): 69423-103-38
ndc (package): 69423-103-61
ndc (package): 69423-103-40
ndc (package): 69423-103-31
ndc (product): 69423-103
ndc11 (package): 69423010331
ndc11 (package): 69423010338
ndc11 (package): 69423010310
ndc11 (package): 69423010368
ndc11 (package): 69423010361
ndc11 (package): 69423010390
ndc11 (package): 69423010365
ndc11 (package): 69423010359
ndc11 (package): 69423010325
ndc11 (package): 69423010340
spl id: 463f04e3-2618-2343-e063-6394a90a6ae4
spl set id: 41709710-539c-3119-e054-00144ff88e88

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.