Indications and uses
Take 1 QuickMelt every 2-4 hours per Directions on inside panel. to reduce the duration of the common cold. reduces the severity of cold symptoms: cough, sore throat, nasal congestion post nasal drip and/or hoarseness.
Cold-EEZE
- Manufacturer
- ProPhase Labs, Inc. | Pharmaloz Manufacturing, Inc.
- Effective date
- 2014-11-25
- Label type
- HUMAN OTC DRUG LABEL
- Version
- 1
- Source
- full-release
- Hydrated at
- 2026-06-01 02:06:19
Label at a glance#
ProductCold-EEZE Daytime and Nighttime QuickMelts
Active ingredientZinc Gluconate, VALERIAN, Chamomile
Label structure18 sections
Dosage and administration
Take Cold-EEZE ® Daytime QuickMelts ® when you have cold symptoms Adults and Children 12 years and over: Dissolve entire tablet in mouth. Do not chew. Do not swallow whole. Take 1 tablet at the onset of symptoms. Repeat every 2-4 hours as needed until all symptoms subside. Do not eat or drink for 15 minutes after use, otherwise, drink plenty of fluids. Recommended daily dose is 6 tablets for adults and 4 tablets f...
Storage and handling
Do not take Cold-EEZE ® QuickMelts ® on an empty stomach to avoid possible minor stomach upset. Store in a cool and dry place.
Contacts and useful links#
Label contents#
Full prescribing information#
SPL UNCLASSIFIED SECTION
Cold-EEZE® Daytime QuickMelts® (AM)
Drug Facts
Active ingredient (per tablet)
Zincum Gluconicum 1X
Purpose
Cold Remedy
Uses
Take 1 QuickMelt every 2-4 hours per Directions on inside panel.
- to reduce the duration of the common cold.
- reduces the severity of cold symptoms: cough, sore throat, nasal congestion post nasal drip and/or hoarseness.
Warnings
Ask a doctor before use if you
- are taking minocycline, doxycycline, tetracycline or are on Coumadin therapy, as zinc treatment may inhibit the absorption of these medicines.
OTC - STOP USE SECTION
Stop use and ask your healthcare practitioner if symptoms persist beyond 7 days.
OTC - WHEN USING SECTION
Cold-EEZE® QuickMelts® Daytime is formulated to reduce the duration of the common cold and its symptoms and is insufficient treatment for Influenza or Allergies.
OTC - PREGNANCY OR BREAST FEEDING SECTION
If pregnant or breast feeding, ask a healthcare practitioner before use.
OTC - KEEP OUT OF REACH OF CHILDREN SECTION
Keep out of reach of children.
Directions
- Take Cold-EEZE® Daytime QuickMelts® when you have cold symptoms
- Adults and Children 12 years and over:
- Dissolve entire tablet in mouth. Do not chew.
Do not swallow whole. - Take 1 tablet at the onset of symptoms.
- Repeat every 2-4 hours as needed until all symptoms subside.
- Do not eat or drink for 15 minutes after use, otherwise, drink plenty of fluids.
- Recommended daily dose is 6 tablets for adults and 4 tablets for ages 12-17 years.
- Dissolve entire tablet in mouth. Do not chew.
- For children under 12 years of age, consult a healthcare practitioner before use.
Other information
- Do not take Cold-EEZE® QuickMelts® on an empty stomach to avoid possible minor stomach upset.
- Store in a cool and dry place.
Inactive ingredients
crospovidone, FD&C Red # 40, glycine, magnesium stearate, malic acid, mannitol, microcrystalline cellulose, natural mixed berry flavor, natural menthol flavor, polyethylene glycol, silicon dioxide, sodium lauryl sulfate, sodium starch glycolate, stevia, sucralose, talc.
SPL UNCLASSIFIED SECTION
Cold-EEZE® Nighttime QuickMelts® (PM)
Drug Facts
OTC - ACTIVE INGREDIENT SECTION
OTC - PURPOSE SECTION
| Active ingredients (per tablet) | Purpose |
| Zincum Gluconicum 1X | Cold Remedy |
| Valeriana Officinalis 1X | Sleep Disorder Remedy |
| Chamomile (Matricaria recutita) 2X | Relaxation and Calming |
Uses
Take 1 Nighttime QuickMelt 1 hour before bedtime per Directions on inside panel.
- to reduce the duration of the common cold.
- reduces the severity of cold symptoms: cough, sore throat, nasal congestion post nasal drip and/or hoarseness.
- helps to relax and sleep easier to get rested.
Warnings
Ask a doctor before using Cold-EEZE®
Nighttime QuickMelts® if you
- are taking fluvoxamine (Luvox), minocycline, doxycycline, tetracycline or are on Coumadin therapy, as zinc treatment may inhibit the absorption of these medicines.
- are under medical supervision and/or are taking tranquilizers, sedatives or anti-seizure medicines.
- do not take concomitantly with loperamide.
OTC - STOP USE SECTION
Stop use and ask your healthcare practitioner if symptoms persist beyond 7 days.
OTC - WHEN USING SECTION
Cold-EEZE® Nighttime QuickMelts® is a combination product formulated to help you to sleep easier and to reduce the duration of the common cold and its symptoms and is insufficient treatment for Influenza or Allergies.
OTC - DO NOT USE SECTION
Do not take Cold-EEZE® Nighttime QuickMelts® while operating a motor vehicle or machinery or consuming alcohol.
Allow 6-8 hours for sleep after taking tablet.
OTC - PREGNANCY OR BREAST FEEDING SECTION
If pregnant or breast feeding, ask a healthcare practitioner before use.
OTC - KEEP OUT OF REACH OF CHILDREN SECTION
Keep out of reach of children.
Directions
- Take Cold-EEZE® Nighttime QuickMelts® at night when you have cold symptoms.
- Adults;
- Dissolve entire tablet in mouth. Do not chew.
Do not swallow whole. - Take 1 Nighttime tablet 1 hour before bedtime.
- Do not eat or drink for 15 minutes after use, otherwise, drink plenty of fluids.
- Dissolve entire tablet in mouth. Do not chew.
- Recommended dose is 1 tablet for adults.
- For individuals under the age of 18, consult a healthcare practitioner before use.
Other information
- Do not take Cold-EEZE® QuickMelts® on an empty stomach to avoid possible minor stomach upset.
- Store in a cool and dry place.
Inactive ingredients
crospovidone, FD&C Blue #1 & #2, glycine, magnesium stearate, malic acid, maltodextrin, mannitol, microcrystalline cellulose, natural mixed berry flavor, natural menthol flavor, polyethylene glycol, sodium lauryl sulfate, silicon dioxide, sodium starch glycolate, stevia, sucralose, talc.
Questions or Comments
Call 1-800-505-2653 (M-F: 9AM-5PM EST)
SPL UNCLASSIFIED SECTION
Manufactured for and
Distributed by:
ProPhase Labs, Inc.
P.O. Box 1349, Doylestown
PA 18901
PRINCIPAL DISPLAY PANEL - Kit Carton
NEW QuickMelts®
GREAT
TASTE
Cold-EEZE®
Zinc Gluconate Glycine
COLD REMEDY
CLINICALLY PROVEN
INGREDIENT
Daytime
Nighttime
#1 Pharmacist Recommended
Daytime
- Shortens your cold,
works faster™ - Non-drowsy
Nighttime
- Shortens your cold,
works faster™ - Fall asleep faster,
naturally - Non-habit forming
18 MELTS
(Daytime)
QuickMelts®
Natural
Mixed Berry Flavor
Homeopathic
6 MELTS
(Nighttime)
DailyMed Product Concepts#
| Product concept | Relation | Version | Effective |
|---|---|---|---|
| f47a510b-6679-4664-b2d6-47b5c4afe7cc | Product name | 4 | 20260217 |
| 030ce964-9b2d-45aa-b5d3-f78ce03ef61c | Product name | 2 | 20250515 |
| 0306390c-dd77-4363-afe0-63c58088b2a1 | Product name | 1 | 20220120 |
| 503ea967-4b9c-48cf-9e87-c7975295849d | Product name | 2 | 20220120 |
| a62a50ac-1535-4461-9768-8ae703e2e9fb | Product name | 1 | 20210525 |
| 0ca1d589-929b-4b33-bc5b-1d84abdafa6a | Product name | 1 | 20150324 |
| fc363c46-397b-4476-ac0f-70e43e8e4592 | Product name | 1 | 20150324 |
| 190f2a5b-bbc8-65c7-fcb0-97891307b917 | Product name | 1 | 20140508 |
| 9514609b-a2a9-f8ec-6ba6-3f8e5ee89877 | Product name | 1 | 20140508 |
| bc07ef78-e82d-0c19-31f4-31f263780582 | Product name | 1 | 20140508 |
FDA-Initiated Inactive NDC Indexing#
| NDC | Effective | Action | Document | Indexing SPL | Related label |
|---|---|---|---|---|---|
| 61941-0225-4 | 2020-01-31 | C162847 | 48780-1 | 9d75b9cf-d5fe-f424-e053-dadaa90a57ce | Cold-EEZE ® Daytime/Nighttime QuickMelts ® |
DailyMed Package Descriptions#
| Package NDC | Product | Description | Form | Quantity | Strength | SPL version |
|---|---|---|---|---|---|---|
| 61941-0225-4 | Cold-EEZE Daytime and Nighttime QuickMelts | 1 in 1 CARTON | KIT | 1 | 1 |
DailyMed Dashboard NDC Coverage#
| NDC | Dashboard title | SPL version | Validation | Dashboard ZIP |
|---|---|---|---|---|
| 61941-0225 | COLD-EEZE DAYTIME AND NIGHTTIME QUICKMELTS (ZINC GLUCONATE, VALERIAN, AND CHAMOMILE) KIT [PROPHASE LABS, INC.] | 1 | Legacy NDC, 1 package rows | 20150114_42739447-8fa8-4f03-9035-2e44671feb04.zip |
DailyMed Socrata Ingredients#
| Ingredient | Type | UNII | SPL version | Uploaded |
|---|---|---|---|---|
| Chamomile | ACTIVE INGREDIENT | FGL3685T2X | 1 | |
| VALERIAN | ACTIVE INGREDIENT | JWF5YAW3QW | 1 | |
| Zinc Gluconate | ACTIVE INGREDIENT | U6WSN5SQ1Z | 1 | |
| Chamomile | ACTIVE MOIETY | FGL3685T2X | 1 | |
| VALERIAN | ACTIVE MOIETY | JWF5YAW3QW | 1 | |
| ZINC CATION | ACTIVE MOIETY | 13S1S8SF37 | 1 | |
| CELLULOSE, MICROCRYSTALLINE | INACTIVE INGREDIENT | OP1R32D61U | 1 | |
| Crospovidone | INACTIVE INGREDIENT | 68401960MK | 1 | |
| FD&C BLUE NO. 1 | INACTIVE INGREDIENT | H3R47K3TBD | 1 | |
| FD&C BLUE NO. 2 | INACTIVE INGREDIENT | L06K8R7DQK | 1 | |
| FD&C RED NO. 40 | INACTIVE INGREDIENT | WZB9127XOA | 1 | |
| Glycine | INACTIVE INGREDIENT | TE7660XO1C | 1 | |
| MAGNESIUM STEARATE | INACTIVE INGREDIENT | 70097M6I30 | 1 | |
| MALIC ACID | INACTIVE INGREDIENT | 817L1N4CKP | 1 | |
| MALTODEXTRIN | INACTIVE INGREDIENT | 7CVR7L4A2D | 1 | |
| MANNITOL | INACTIVE INGREDIENT | 3OWL53L36A | 1 | |
| POLYETHYLENE GLYCOLS | INACTIVE INGREDIENT | 3WJQ0SDW1A | 1 | |
| SILICON DIOXIDE | INACTIVE INGREDIENT | ETJ7Z6XBU4 | 1 | |
| SODIUM LAURYL SULFATE | INACTIVE INGREDIENT | 368GB5141J | 1 | |
| SODIUM STARCH GLYCOLATE TYPE A POTATO | INACTIVE INGREDIENT | 5856J3G2A2 | 1 | |
| STEVIA REBAUDIUNA LEAF | INACTIVE INGREDIENT | 6TC6NN0876 | 1 | |
| SUCRALOSE | INACTIVE INGREDIENT | 96K6UQ3ZD4 | 1 | |
| TALC | INACTIVE INGREDIENT | 7SEV7J4R1U | 1 |
Products#
Every source-derived product name is available through these pages.
- Cold-EEZE Daytime and Nighttime QuickMelts
- Zinc Gluconate, Valerian, and Chamomile
- Cold-EEZE Daytime QuickMelts
- Zinc Gluconate
- ZINC CATION
- Glycine
- MALIC ACID
- Crospovidone
- FD&C RED NO. 40
- MAGNESIUM STEARATE
- MANNITOL
- CELLULOSE, MICROCRYSTALLINE
- POLYETHYLENE GLYCOLS
- SODIUM LAURYL SULFATE
- SILICON DIOXIDE
- SODIUM STARCH GLYCOLATE TYPE A POTATO
- STEVIA REBAUDIUNA LEAF
- SUCRALOSE
- TALC
- Cold-EEZE Nighttime QuickMelts
- VALERIAN
- Chamomile
- FD&C BLUE NO. 1
- FD&C BLUE NO. 2
- MALTODEXTRIN
NDC Codes#
| Product NDC | Package NDC |
|---|---|
| 61941-0225 | 61941-0225-4 |
Ingredients#
Every source-derived ingredient row is available through these pages.
Source Document#
Inactive ingredient matches#
Inactive Ingredient Database values describe FDA-listed use contexts. The match method and ambiguity count are shown because ingredient names, routes, and dosage forms are not always unique. Browse recovered IID releases and source provenance.
| DailyMed ingredient | IID ingredient | UNII | Dosage form / route | Potency | Maximum daily exposure | Match |
|---|---|---|---|---|---|---|
| MAGNESIUM STEARATE | MAGNESIUM STEARATE | 70097M6I30 | TABLET, FOR SUSPENSION / ORAL | 131 mg | ||
| TALC | TALC | 7SEV7J4R1U | ELIXIR / ORAL | 4.5 mg/5ml | ||
| MANNITOL | MANNITOL | 3OWL53L36A | TABLET, FILM COATED, EXTENDED RELEASE / ORAL | 543 mg | ||
| MALTODEXTRIN | MALTODEXTRIN | 7CVR7L4A2D | CAPSULE / ORAL | 200 mg | ||
| FD&C BLUE NO. 1 | FD&C BLUE NO. 1 | H3R47K3TBD | TABLET, DELAYED RELEASE / ORAL | 0.01 mg | ||
| FD&C BLUE NO. 1 | FD&C BLUE NO. 1 | H3R47K3TBD | LIQUID / ORAL | NA | ||
| CELLULOSE, MICROCRYSTALLINE | MICROCRYSTALLINE CELLULOSE | OP1R32D61U | TABLET, ORALLY DISINTEGRATING / ORAL | 1800 mg | ||
| FD&C BLUE NO. 1 | FD&C BLUE NO. 1 | H3R47K3TBD | PASTE / DENTAL | NA | ||
| MANNITOL | MANNITOL | 3OWL53L36A | LOZENGE / ORAL | 20546 mg | ||
| Glycine | GLYCINE | TE7660XO1C | POWDER, FOR SUSPENSION / ORAL | 400 mg | ||
| MAGNESIUM STEARATE | MAGNESIUM STEARATE | 70097M6I30 | POWDER, FOR SUSPENSION / ORAL | 120 mg | ||
| MAGNESIUM STEARATE | MAGNESIUM STEARATE | 70097M6I30 | IMPLANT / INTRAVITREAL | NA | ||
| MANNITOL | MANNITOL | 3OWL53L36A | GEL / OPHTHALMIC | 25 mg | ||
| MAGNESIUM STEARATE | MAGNESIUM STEARATE | 70097M6I30 | CREAM / TOPICAL | NA | ||
| MANNITOL | MANNITOL | 3OWL53L36A | TABLET, ORALLY DISINTEGRATING, DELAYED RELEASE / ORAL | 1568 mg | ||
| CELLULOSE, MICROCRYSTALLINE | MICROCRYSTALLINE CELLULOSE | OP1R32D61U | CAPSULE, EXTENDED RELEASE / ORAL | 1246 mg | ||
| SUCRALOSE | SUCRALOSE | 96K6UQ3ZD4 | TABLET, FOR SUSPENSION / ORAL | 65 mg | ||
| Glycine | GLYCINE | TE7660XO1C | PASTE, DENTIFRICE / DENTAL | 0.34 %w/w | ||
| MANNITOL | MANNITOL | 3OWL53L36A | INJECTION, POWDER, FOR SUSPENSION / SUBCUTANEOUS | 180 mg | ||
| MANNITOL | MANNITOL | 3OWL53L36A | TABLET, CHEWABLE, EXTENDED RELEASE / ORAL | 616 mg | ||
| CELLULOSE, MICROCRYSTALLINE | MICROCRYSTALLINE CELLULOSE | OP1R32D61U | IMPLANT / INTRAVITREAL | 1.66 mg | ||
| MANNITOL | MANNITOL | 3OWL53L36A | INJECTION, SOLUTION / INTRAVENOUS | 15400 mg | ||
| TALC | TALC | 7SEV7J4R1U | CAPSULE, COATED, EXTENDED RELEASE / ORAL | 20 mg | ||
| SILICON DIOXIDE | SILICON DIOXIDE | ETJ7Z6XBU4 | GEL / NASAL | 20 mg | ||
| FD&C RED NO. 40 | FD&C RED NO. 40 | WZB9127XOA | CAPSULE, COATED, EXTENDED RELEASE / ORAL | NA | ||
| FD&C BLUE NO. 1 | FD&C BLUE NO. 1 | H3R47K3TBD | CONCENTRATE / ORAL | NA | ||
| Glycine | GLYCINE | TE7660XO1C | INJECTION, SOLUTION / INTRAVENOUS | 0.42 %w/v | ||
| SUCRALOSE | SUCRALOSE | 96K6UQ3ZD4 | TABLET, ORALLY DISINTEGRATING / ORAL | 60 mg | ||
| Glycine | GLYCINE | TE7660XO1C | CAPSULE / ORAL | 62 mg | ||
| FD&C RED NO. 40 | FD&C RED NO. 40 | WZB9127XOA | TABLET, COATED / ORAL | 0.1 mg | ||
| SUCRALOSE | SUCRALOSE | 96K6UQ3ZD4 | TABLET, EXTENDED RELEASE / ORAL | 1 mg | ||
| MAGNESIUM STEARATE | MAGNESIUM STEARATE | 70097M6I30 | CAPSULE, COATED, EXTENDED RELEASE / ORAL | NA | ||
| SILICON DIOXIDE | SILICON DIOXIDE | ETJ7Z6XBU4 | FILM, SOLUBLE / ORAL | 2 mg | ||
| FD&C BLUE NO. 2 | FD&C BLUE NO. 2 | L06K8R7DQK | CAPSULE, EXTENDED RELEASE / ORAL | 4 mg | ||
| SILICON DIOXIDE | SILICON DIOXIDE | ETJ7Z6XBU4 | TABLET, EXTENDED RELEASE / ORAL | 450 mg | ||
| Glycine | GLYCINE | TE7660XO1C | INJECTION, POWDER, FOR SOLUTION / INTRAVENOUS | 3.76 mg | ||
| SILICON DIOXIDE | SILICON DIOXIDE | ETJ7Z6XBU4 | TABLET / ORAL | 750 mg | ||
| Glycine | GLYCINE | TE7660XO1C | CAPSULE, DELAYED RELEASE / ORAL | 50 mg | ||
| TALC | TALC | 7SEV7J4R1U | GRANULE, DELAYED RELEASE / ORAL | 525 mg | ||
| SODIUM LAURYL SULFATE | SODIUM LAURYL SULFATE | 368GB5141J | TABLET, EXTENDED RELEASE / ORAL | 320 mg | ||
| FD&C RED NO. 40 | FD&C RED NO. 40 | WZB9127XOA | CONCENTRATE / ORAL | 0.04 mg/1ml | ||
| MANNITOL | MANNITOL | 3OWL53L36A | INJECTION, SUSPENSION / INTRAVENOUS | 2.5 %w/v | ||
| TALC | TALC | 7SEV7J4R1U | SUSPENSION / ORAL | 234 mg | ||
| Glycine | GLYCINE | TE7660XO1C | TABLET, CHEWABLE / ORAL | 267 mg | ||
| SUCRALOSE | SUCRALOSE | 96K6UQ3ZD4 | SPRAY, METERED / NASAL | 2 mg | ||
| Glycine | GLYCINE | TE7660XO1C | INJECTION, POWDER, FOR SOLUTION / SUBCUTANEOUS | 0.5 mg | ||
| SUCRALOSE | SUCRALOSE | 96K6UQ3ZD4 | SOLUTION / ORAL | 800 mg | ||
| SILICON DIOXIDE | SILICON DIOXIDE | ETJ7Z6XBU4 | SUSPENSION / ORAL | 400 mg | ||
| SODIUM LAURYL SULFATE | SODIUM LAURYL SULFATE | 368GB5141J | TABLET, ORALLY DISINTEGRATING, DELAYED RELEASE / ORAL | 3 mg | ||
| MANNITOL | MANNITOL | 3OWL53L36A | GRANULE / ORAL | 1328 mg | ||
| CELLULOSE, MICROCRYSTALLINE | MICROCRYSTALLINE CELLULOSE | OP1R32D61U | SUSPENSION / ORAL | 1600 mg | ||
| MAGNESIUM STEARATE | MAGNESIUM STEARATE | 70097M6I30 | PELLET / ORAL | 24 mg | ||
| MAGNESIUM STEARATE | MAGNESIUM STEARATE | 70097M6I30 | RING / VAGINAL | 2 mg | ||
| SILICON DIOXIDE | SILICON DIOXIDE | ETJ7Z6XBU4 | GEL / VAGINAL | 8 %w/w | ||
| CELLULOSE, MICROCRYSTALLINE | MICROCRYSTALLINE CELLULOSE | OP1R32D61U | TABLET / BUCCAL | 18 mg | ||
| FD&C BLUE NO. 2 | FD&C BLUE NO. 2 | L06K8R7DQK | TABLET / BUCCAL | 0.01 mg | ||
| MALIC ACID | MALIC ACID | 817L1N4CKP | POWDER, FOR SUSPENSION / ORAL | 1392 mg | ||
| SODIUM LAURYL SULFATE | SODIUM LAURYL SULFATE | 368GB5141J | TABLET, COATED / ORAL | 123 mg | ||
| FD&C BLUE NO. 1 | FD&C BLUE NO. 1 | H3R47K3TBD | SOLUTION / RECTAL | 0.01 %w/v | ||
| MANNITOL | MANNITOL | 3OWL53L36A | INJECTION / INTRAMUSCULAR | 106.6 mg |
openFDA label cross-check#
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| c1cf8137-5dad-44d8-b08d-5404467e05b0 | 42739447-8fa8-4f03-9035-2e44671feb04 | 2014-11-25 | Warnings | c1cf8137-5dad-44d8-b08d-5404467e05b0 42739447-8fa8-4f03-9035-2e44671feb04 |
Reported adverse events (FAERS/openFDA)#
Adverse event summaries are temporarily unavailable. Other product information remains available.