USES: This is a topical cream that contains bio-identical micronized USP progesterone derived from wild yam, blended with phytoestrogens. When applied topically to the skin, it may help to balance your hormones and also to provide support for perimenopause and menopause. Apply once or twice a day. Massage into wrists, inner arms, thighs, chest, or apply or use as directed by your physician.
www.WiseEssentials.com
www.fda.gov/drugs/enforcement-activities-fda/unapproved-drugs
www.accessdata.fda.gov/scripts/medwatchwww.fda.gov/safety/recalls-market-withdrawals-safety-alerts
www.ncbi.nlm.nih.gov/books/NBK501345
www.clinicaltrials.gov/search?term=PROGESTERONE&viewType=Table#classicRedirect
go.drugbank.com/drugs/DB00396Femarone 20
DRUG FACTS Active Ingredient
Micronized Progesterone USP (Wild Yam 2%)
UsesThis topical cream contains USP progesterone derived from wild yam. Applied to the skin may help balance your hormones and provide support for peri-menopause and menopause symptoms.
20 mg per p1/4 tsp of USP progesterone.
Inactive Ingredients:
Water, Dioscorea Villosa Extract (Wild Yam), Vitex Agnus-Castus, Organic Cocos Nucifera (Coconut Oil*, Organic Vegetable Glycerin*, Emulsifying Wax NF, Olive M 1000, Glyceryl Stearate, Radish Root Extract*, Organic Aloe Barbadensis Leaf (Aloe Vera)*, Allantoin, Xanthan Gum, Organic Jojoba Oil*, Organic Shea Butter*, Made with organic Ingredients
Warnings: For external cosmetic use only. Always consult your healthcare provider before using. Cease use and seek medical attention if skin irritation you or any negative reaction. If pregnant or nursing, consult a healthcare professional before use.
California Prop 65 Law requires this statement. This product contains progesterone, a chemical known only to the State of California to cause cancer.
Keep out of reach of children
Store in a cold, dry place
Directions:Use twice daily. Massage into inner arms, wrist, chest, or thighs or as directed by your Physician.
Questions? support@wiseessentials.com
Wise Essentials, St. Paul, MN 55116
MADE IN
Distributed and Manufactured in a certified
Kosher and FDA registered facility for
Wise Essentials St. Paul, MN 55116
Visit us at: www.WiseEssentials.com
Micronized Progesterone USP, (Wild Yam) 2%
Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs For further information about unapproved drugs, https://www.fda.gov/drugs/enforcement-activities-fda/unapproved-drugs
This is a topical cream that contains bio-identical micronized USP progesterone derived from wild yam, blended with phytoestrogens. When applied topically to the skin, it may help to balance your hormones, and also to provide support for peri menopause and menopausal symptoms.
USES: This is a topical cream that contains bio-identical micronized USP progesterone derived from wild yam, blended with phytoestrogens. When applied topically to the skin, it may help to balance your hormones and also to provide support for perimenopause and menopause.
Apply once or twice a day. Massage into wrists, inner arms, thighs, chest, or apply or use as directed by your physician.
If pregnant or nursing or if you have a serious medical condition, consult a healthcare professional before using this product.
Keep out of Reach of Children.
Apply once or twice a day. Massage into wrists, inner arms, thighs, chest, or apply to together or use as directed by your physician.
Water, Wild Yam Extract, Chaste Tree Berry, Coconut Oil Organic, Vegetable Glycerin USP, Emulsifying Wax NF, Olivem 1000, Glyceryl Stearate, Radish Root Extract, Aloe Vera Powder Organic, Jojoba Oil Organic, Allantoin, Shea Butter Organic
QUESTIONS?
Contact support@wiseessentials.com
Report Adverse Events click here www.accessdata.fda.gov/scripts/medwatch
FDA Safety Recalls Click here www.fda.gov/safety/recalls-market-withdrawals-safety-alerts
Presence in Breast Milk Click here www.ncbi.nlm.nih.gov/books/NBK501345
Clinical Trials.Click here https://www.clinicaltrials.gov/search?term=PROGESTERONE&viewType=Table#classicRedirect
Biochemcical Date Summary. Click here. https://go.drugbank.com/drugs/DB00396
WARNINGS: If pregnant or nursing or if you have a serious medical condition, consult a healthcare professional before using this product.
KEEP OUT OF REACH OF CHILDREN Store in a cool, dry place
Always consult your healthcare provider before using or if pregnant or nursing. Cease use and seek medical attention if skin irritation or a negative reaction.
Keep out of reach of children. Store in a cool, dry place.
California Prop 65 Law requires this statement: This product contains progesterone,
a chemical known only to the State of California to cause cancer. Cease using this product
and seek medical attention if skin irritation or other negative reactions occur.
| Class | Version | Type | Effective |
|---|---|---|---|
| PROGESTERONE Pharmacologic Class Indexing | 2 | Indexing - Pharmacologic Class | 20180813 |
| Product concept | Relation | Version | Effective |
|---|---|---|---|
| b46148e2-ee15-98d5-12f0-f5ec8745f6fc | Product name | 3 | 20220927 |
| 76820076-f087-4073-b1d1-aa04b361335e | Product name | 2 | 20220921 |
| d3229c1a-4e51-4e04-9b13-00d24fd35242 | Product name | 1 | 20200821 |
| 213f0591-95c1-b398-40b7-08b31f66b026 | Product name | 4 | 20190206 |
| 85b2d644-53b2-f2dc-4dbc-859116ce56c0 | Product name | 1 | 20140508 |
| d048f0e3-3c40-8816-8c5c-0ca5cd189aac | Product name | 1 | 20140508 |
| Package NDC | Product | Description | Form | Quantity | Strength | SPL version |
|---|---|---|---|---|---|---|
| 87250-001-11 | Femarone 20 | 58 g in 1 JAR | CREAM | 58 | 1 |
Every source-derived product name is available through these pages.
| Product NDC | Package NDC |
|---|---|
| 87250-001 | 87250-001-11 |
Every source-derived ingredient row is available through these pages.
| Name | UNII | Kind |
|---|---|---|
| CHASTE TREE FRUIT | 433OSF3U8A | IACT |
| COCOS NUCIFERA (COCONUT) OIL | Q9L0O73W7L | IACT |
| JOJOBA OIL | 724GKU717M | IACT |
| PROGESTERONE | 4G7DS2Q64Y | ACTIB |
| GLYCERIN | PDC6A3C0OX | IACT |
| SORBITAN OLIVATE | MDL271E3GR | IACT |
| DIOSCOREA VILLOSA TUBER | IWY3IWX2G8 | IACT |
| ALLANTOIN | 344S277G0Z | IACT |
| RADISH | EM5RP35463 | IACT |
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| Femarone 20 | FEMARONE 20 | Wise Essentials LLC | 44ea74ce-2ba1-e578-e063-6394a90ab72d | 2025-12-13 | Warnings | 87250-001-11 87250-001 87250000111 44ea74ce-2ba2-e578-e063-6394a90ab72d 44ea74ce-2ba1-e578-e063-6394a90ab72d |
Adverse event summaries are temporarily unavailable. Other product information remains available.
