FDA.reportPublic FDA data

CVS Lidocaine Pain Relief Cream

Manufacturer
CVS Pharmacy | Natural Essentials, Inc.
Effective date
2026-01-16
Label type
HUMAN OTC DRUG LABEL
Version
2
Source
full-release
Hydrated at
2026-06-01 01:33:53

Label at a glance#

ProductCVS Lidocaine Pain Relief Cream
Active ingredientLIDOCAINE HYDROCHLORIDE
Label structure8 sections

Dosage and administration

Adults and children over 12 years: Apply a thin layer to affect area every 6 to 8 hours, not to exceed 3 applications in a 24 hour period. massage into painful area until thoroughly absorbed into skin Children 12 years or younger: ask a doctor

Label contents#

Full prescribing information#

Active ingredient

OTC - ACTIVE INGREDIENT SECTION

Lidocaine HCl 4%

Purpose

OTC - PURPOSE SECTION

Topical Anesthetic

Use

INDICATIONS & USAGE SECTION

Temporarily relieves minor pain

Warnings

WARNINGS SECTION

For external use only

Do not use

OTC - DO NOT USE SECTION

  • if you have serious foot problems, such as ulcers or infections
  • on large areas of the body
  • on cut, irritated or swollen skin
  • on puncture wounds
  • for more than one week without consulting a doctor

When using this product

OTC - WHEN USING SECTION

  • use only as directed. Read and follow all directions and warning on this carton.
  • do not allow contact with the eyes and mucus membranes
  • do not bandage tightly or apply local heat (such as heating pads) or a medicated patch to the area of use
  • do not use at the same time as other topical analgesics

Stop use and ask a doctor if

OTC - STOP USE SECTION

  • condition worsens
  • redness is present
  • irritation develops
  • symptoms persist for more than 7 days or clear up and occur again within a few days

If pregnant or breast-feeding

OTC - PREGNANCY OR BREAST FEEDING SECTION

ask a health professional before use.

Keep out of reach of children.

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

If swallowed, get medical help or contact a Poison Control Center right away.

Directions

DOSAGE & ADMINISTRATION SECTION

Adults and children over 12 years:

  • Apply a thin layer to affect area every 6 to 8 hours, not to exceed 3 applications in a 24 hour period.
  • massage into painful area until thoroughly absorbed into skin

Children 12 years or younger: ask a doctor

Other information

OTHER SAFETY INFORMATION

Store in a cool dry area.

Child-resistant packaging: Close cap tightly after use.

Inactive ingredients

INACTIVE INGREDIENT SECTION

acrylates/C10-30 alkyl acrylate crosspolymer, alcohol denat., aloe barbadensis leaf juice, aminomethyl propanol, benzoic acid, C30-45 alkyl cetearyl dimethicone crosspolymer, caprylyl methicone, cetearyl alcohol, ceteth-20 phosphate, dicetyl phosphate, dimethicone, disodium EDTA, glyceryl stearate, hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, isohexadecane, polysorbate 60, propanediol, sorbitan caprylate, steareth-2, steareth-21, water

Principal Display Panel - 121 g Carton

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

CVS

Health®

Compare to the active ingredients in Aspercreme ® with Lidocaine †

Maximum Strength

Lidocaine concentration without a prescription ‡

Lidocaine Pain Relief Cream

Lidocaine HCl 4%

External analgesic

Fragrance Free

  • Numbs pain away
  • Non-irritating pain relief
  • Non-greasy

‡Among OTC Topical Analgesics

with Aloe

Package Contains One Bottle

NET WT 4.3 OZ (121 g)

CartonCarton

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYSPL version
1010895lidocaine HCl 4 % Topical CreamPSN2
1010895lidocaine hydrochloride 40 MG/ML Topical CreamSCD2
1010895lidocaine hydrochloride 4 % Topical CreamSY2

DailyMed Pharmacologic Classes#

Class, Version, Type table
ClassVersionTypeEffective
LIDOCAINE Pharmacologic Class Indexing2Indexing - Pharmacologic Class20180813

Product Linked Resources#

Resource, Code type, Value table
ResourceCode typeValueEquivalent identifiersSource image
BarcodeEAN-130050428147061GTIN-13: 0050428147061
EAN-13: 0050428147061
GTIN-12: 050428147061
UPC-A: 050428147061
GTIN storage (14 digits): 00050428147061		4825_NatEss_405343_MS_Lido4pct_PainRelCream comp.jpg

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
070fbed5-7088-434a-a7ce-f2a64d8d40acProduct name220260107
bee66ce1-adb7-9d3b-67d9-582e4c54e80fProduct name520250819
860a93dc-4863-49cc-b284-6bbe8191bc48Product name420250214
eaba870a-6a9d-442e-8643-87b3f558a451Product name120250117
9b4cf230-fd05-41d5-98c6-5db9ecb27b86Product name120230117
c6f86816-7da6-43ea-8c25-ac9758311cc5Product name120220118
7d755fa1-1087-4dcd-98f0-6d4bba479a57Product name320210602
aed701d5-9c75-dfaf-7154-cde46179faeaProduct name920200313
fa8b5901-e681-426f-82fe-54f6d81ec698Product name420180619
332d03e4-aa24-4b11-841a-02bf41081920Product name120171221
c08ab52f-2fc8-4409-9d9f-ed8edc0bd070Product name120171221
252e11b6-1a9a-4283-a242-df2c129c496dProduct name320170717
68ed98f8-24c2-44a0-944a-6d36e82ce25aProduct name120141222
1cd42bc2-a430-c72b-636d-991b235fbf80Product name120140508
49fa150c-f0de-cce7-3d9c-993ed81c5698Product name120140508
4d7ae718-ed00-bae8-2abe-9eaec1eef7ffProduct name120140508
9137811f-f279-8640-5aeb-99fa2145d64dProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
51316-379-43CVS Lidocaine Pain Relief Cream1 in 1 CARTONCREAM12
51316-379-43CVS Lidocaine Pain Relief Cream121 g in 1 BOTTLE, PLASTICCREAM1212

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 25 matching rows.

NDC Codes#

Product NDC, Package NDC table
Product NDCPackage NDC
51316-37951316-379-43

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 22 matching rows.

Name, UNII, Kind table
NameUNIIKind
LIDOCAINE HYDROCHLORIDEV13007Z41AACTIR
PROPANEDIOL5965N8W85TIACT
BENZOIC ACID8SKN0B0MIMIACT
ISOHEXADECANE918X1OUF1EIACT
HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER (45000 MPA.S AT 1%)86FQE96TZ4IACT
STEARETH-2153J3F32P58IACT
C30-45 ALKYL CETEARYL DIMETHICONE CROSSPOLYMER4ZK9VP326RIACT
CAPRYLYL METHICONEQ95M2P1KJLIACT
CETEARYL ALCOHOL2DMT128M1SIACT
AMINOMETHYL PROPANOLLU49E6626QIACT
ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER (60000 MPA.S)8Z5ZAL5H3VIACT
DIMETHICONE92RU3N3Y1OIACT
EDETATE DISODIUM7FLD91C86KIACT
ALOE BARBADENSIS LEAF JUICERUE8E6T4NBIACT
SORBITAN CAPRYLATE1VTA8DCP5QIACT
STEARETH-2V56DFE46J5IACT
POLYSORBATE 60CAL22UVI4MIACT
WATER059QF0KO0RIACT
ALCOHOL3K9958V90MIACT
CETETH-20 PHOSPHATE921FTA1500IACT
DICETYL PHOSPHATE2V6E5WN99NIACT
GLYCERYL STEARATE230OU9XXE4IACT

Source Document#

Source XML

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
CVS Lidocaine Pain Relief CreamLIDOCAINE HYDROCHLORIDECVS Pharmacy45c4f946-13b9-7a0a-e063-6394a90a73532026-01-16WarningsExact identifier
ndc (package): 51316-379-43
ndc (product): 51316-379
ndc11 (package): 51316037943
spl id: 488463f3-9e31-5f18-e063-6294a90afd03
spl set id: 45c4f946-13b9-7a0a-e063-6394a90a7353

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.