WILD YAM AND PROGESTERONE- progesterone, wild yam and progesterone cream

Wild Yam and Progesterone by

Drug Labeling and Warnings

Wild Yam and Progesterone by is a Otc medication manufactured, distributed, or labeled by Wise Essentials LLC. Drug facts, warnings, and ingredients follow.

Drug Details [pdf]

ACTIVE INGREDIENT

Micronized Progesterone USP, (Wild Yam) 2%

KEEP OUT OF REACH OF CHILDREN

Keep out of Reach of Children.

PREGNANT OR BREASTFEEDING

If pregnant or nursing or if you have a serious medical condition, consult a healthcare professional before using this product.

WARNING

WARNINGS: FOR EXTERNAL COSMETIC USE ONLY. If pregnant or nursing or if you have a serious medical condition, consult a healthcare professional before using this product.

Discontinue use if skin irritation or red skin develops, and consult a Physician. Do not use with any other progesterone or progestins. Do not use if the tamper-evident seal is broken or missing. California Prop 65 Law requires this statement: This product contains progesterone, a chemical known only to the State of California to cause cancer. Cease using this product and seek medical attention if skin irritation or other negative reactions occur.

DOSAGE AND USE

Apply once or twice a day. Massage into wrists, inner arms, thighs, chest, or use as directed by your physician. Each 1/4 tsp is 20 mg of progesterone.

PURPOSE

This is a topical cream that contains bio-identical micronized USP progesterone derived from wild yam, blended with phytoestrogens. When applied topically to the skin, it may help to balance your hormones and provide support for peri menopause and menopause.

INDICATIONS AND USAGE

USES: This is a topical cream that contains bio-identical micronized USP progesterone derived from wild yam, blended with phytoestrogens. When applied topically to the skin, it may help to balance your hormones and also to provide support for perimenopause and menopause.

Apply once or twice a day. Massage into wrists, inner arms, thighs, chest, or apply or use as directed by your physician.

QUESTIONS

QUESTIONS?

Contact support@wiseessentials.com

SAFETY

Report Adverse Events click here https://www.accessdata.fda.gov/scripts/medwatch/

FDA Safety Recalls Click here https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts

Presence in Breast Milk Click here https://www.ncbi.nlm.nih.gov/books/NBK501345/

DISCLAIMER

DISCLAIMER

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs For further information about unapproved drugs, https://www.fda.gov/drugs/enforcement-activities-fda/unapproved-drugs

RELATED RESOURCES

Medline Plus. Click here https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&query=PROGESTERONE&_gl=1*f9papn*_ga*MTc2NTIwMjU3MS4xNzY1Njc2NTE5*_ga_7147EPK006*czE3NjU2NzY1MTgkbzEkZzEkdDE3NjU2NzY4NzEkajI1JGwwJGgw*_ga_P1FPTH9PL4*czE3NjU2NzY1MTgkbzEkZzEkdDE3NjU2NzY4NzEkajI1JGwwJGgw

Clinical Trials.Click here https://www.clinicaltrials.gov/search?term=PROGESTERONE&viewType=Table#classicRedirect

Biochemcical Date Summary. Click here. https://go.drugbank.com/drugs/DB00396

INACTIVE INGREDIENTS

Wild Yam Extract, Dioscorea Villosa, Polyacrylamide/Isoparraffin, Laureth, USP Micronized Progesterone (from Wid Yam), Emulsifying Wax NF, Coco Caprylate Caprate, Radish Root Extract, Glycerin Stearate, Olive M 1000, Chaste Tree Berry Extract, Squalane Oil, Cholesterol, Jojoba Oil, Squalane Oil, Vitamins D, Cholesterol, Extracts of Dong Quai, Black Cohosh

PRINCIPAL DISPLAY PANEL

INGREDIENTS AND APPEARANCE

WILD YAM AND PROGESTERONE 
progesterone, wild yam and progesterone cream

Product Information
Product Type	HUMAN OTC DRUG	Item Code (Source)	NDC: 87250-102
Route of Administration	TOPICAL

Active Ingredient/Active Moiety
Ingredient Name	Basis of Strength	Strength
PROGESTERONE (UNII: 4G7DS2Q64Y) (PROGESTERONE - UNII:4G7DS2Q64Y)	PROGESTERONE	20 mg  in 58 g

Inactive Ingredients
Ingredient Name	Strength
GLYCERIN (UNII: PDC6A3C0OX)	30 mg  in 58 g
RADISH (UNII: EM5RP35463)	20 mg  in 58 g
COCO-CAPRYLATE/CAPRATE (UNII: 8D9H4QU99H)	20 mg  in 58 g
SQUALANE (UNII: GW89575KF9)	1 mg  in 58 g
CHOLESTEROL (UNII: 97C5T2UQ7J)	20 mg  in 58 g
DIOSCOREA VILLOSA ROOT (UNII: IWY3IWX2G8)	80 mg  in 58 g
JOJOBA OIL (UNII: 724GKU717M)	5 mg  in 58 g
SORBITAN OLIVATE (UNII: MDL271E3GR)	10 mg  in 58 g
CHASTE TREE (UNII: 433OSF3U8A)	10 mg  in 58 g
ALLANTOIN (UNII: 344S277G0Z)	2 mg  in 58 g

Packaging
#	Item Code	Package Description	Marketing Start Date	Marketing End Date
1	NDC: 87250-102-02	58 g in 1 JAR; Type 0: Not a Combination Product	12/19/2025

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
unapproved drug other		12/19/2025

Labeler - Wise Essentials LLC (080921731)