for the temporary relief of: heartburn, acid indigestion, and sour stomach when accompanied with headache or body aches and pains upset stomach with headache from overindulgence in food or drink headache, body aches, and pain alone
fully dissolve 2 tablets in 4 ounces of water before taking adults and children 12 years and over 2 tablets every 6 hours, or as directed by a doctor do not exceed 7 tablets in 24 hours adults 60 years and over 2 tablets every 6 hours, or as directed by a doctor do not exceed 3 tablets in 24 hours children under 12 years consult a doctor
each tablet contains: sodium 588 mg store at room temperature. Avoid excessive heat. Alka-Seltzer Extra Strength in water contains principally the antacid sodium citrate and the analgesic sodium acetylsalicylate
Drug Facts
| Active ingredients (in each tablet) | Purpose |
|---|---|
| Anhydrous citric acid 1000 mg | Antacid |
| Aspirin 500 mg | Analgesic |
| Sodium bicarbonate (heat-treated) 1985 mg | Antacid |
for the temporary relief of:
Reye’s syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye’s syndrome, a rare but serious illness.
Allergy alert: Aspirin may cause a severe allergic reaction which may include
Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you
Ask a doctor or pharmacist before use if you are
When using this product do not exceed recommended dosage
• feel faint • vomit blood
• have bloody or black stools
• have stomach pain that does not get better
If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
| adults and children 12 years and over | 2 tablets every 6 hours, or as directed by a doctor | do not exceed 7 tablets in 24 hours |
| adults 60 years and over | 2 tablets every 6 hours, or as directed by a doctor | do not exceed 3 tablets in 24 hours |
| children under 12 years | consult a doctor | |
flavor
1-800-986-0369 (Mon - Fri 9AM - 5PM EST)
Alka-
Seltzer
®
ANTACID & PAIN RELIEF MEDICINE
FAST
RELIEF
OF:
Acid Indigestion
Upset Stomach
Heartburn with
Headache
Body Aches
XTRA
STRENGTH
24 EFFERVESCENT TABLETS
| RxCUI | RxNorm string | TTY | SPL version |
|---|---|---|---|
| 1872088 | Alka-Seltzer 500 MG / 1000 MG / 1985 MG Granules for Oral Solution | PSN | 5 |
| 1872085 | aspirin 500 MG / citric acid 1000 MG / sodium bicarbonate 1985 MG Granules for Oral Solution | PSN | 5 |
| 1872088 | aspirin 500 MG / citric acid 1000 MG / sodium bicarbonate 1985 MG Granules for Oral Solution [Alka-Seltzer] | SBD | 5 |
| 1872085 | aspirin 500 MG / citric acid 1000 MG / sodium bicarbonate 1985 MG Granules for Oral Solution | SCD | 5 |
| 1872088 | Alka-Seltzer (aspirin 500 MG / citric acid 1000 MG / sodium bicarbonate 1985 MG) Granules for Oral Solution | SY | 5 |
| 1872085 | ASA 500 MG / Citric Acid 1000 MG / NaHCO3 1985 MG Granules for Oral Solution | SY | 5 |
| 1872088 | ASA 500 MG / Citric Acid 1000 MG / NaHCO3 1985 MG Granules for Oral Solution [Alka-Seltzer] | SY | 5 |
| 1872085 | aspirin 500 MG / citric acid 1000 MG / sodium bicarbonate 1985 MG Powder for Oral Solution | SY | 5 |
| 1872088 | Aspirin 500 MG / Citric Acid 1000 MG / Sodium Bicarbonate 1985 MG Powder for Oral Solution [Alka-Seltzer] | SY | 5 |
| Class | Version | Type | Effective |
|---|---|---|---|
| ANHYDROUS CITRIC ACID Pharmacologic Class Indexing | 3 | Indexing - Pharmacologic Class | 20180813 |
| ASPIRIN Pharmacologic Class Indexing | 3 | Indexing - Pharmacologic Class | 20191108 |
| SODIUM CATION Pharmacologic Class Indexing | 2 | Indexing - Pharmacologic Class | 20180813 |
| Package NDC | Product | Description | Form | Quantity | Strength | SPL version |
|---|---|---|---|---|---|---|
| 0280-0211-24 | Alka-Seltzer Extra Strength | 12 in 1 CARTON | GRANULE, EFFERVESCENT | 12 | 5 | |
| 0280-0211-24 | Alka-Seltzer Extra Strength | 2 in 1 PACKET | GRANULE, EFFERVESCENT | 2 | 5 |
Every source-derived product name is available through these pages.
| Product NDC | Package NDC |
|---|---|
| 0280-0211 | 0280-0211-24 |
Every source-derived ingredient row is available through these pages.
| Name | UNII | Kind |
|---|---|---|
| LEMON | 24RS0A988O | IACT |
| ANHYDROUS CITRIC ACID | XF417D3PSL | ACTIB |
| SODIUM BICARBONATE | 8MDF5V39QO | ACTIB |
| ASPIRIN | R16CO5Y76E | ACTIB |
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| Alka-Seltzer Extra Strength | ANHYDROUS CITRIC ACID, SODIUM BICARBONATE, AND ASPIRIN | Bayer HealthCare LLC. | 49b73bd5-6465-05eb-e054-00144ff88e88 | 2025-12-04 | Warnings | 0280-0211-24 0280-0211 00280021124 45266611-610c-a481-e063-6394a90a1bf0 49b73bd5-6465-05eb-e054-00144ff88e88 |
Adverse event summaries are temporarily unavailable. Other product information remains available.