FDA.reportPublic FDA data

SHISEIDO BENEFIANCE WRINKLE SMOOTHING DAY CREAM

Manufacturer
SHISEIDO AMERICAS CORPORATION | Shiseido America Inc.
Effective date
2026-01-05
Label type
HUMAN OTC DRUG LABEL
Version
3
Source
full-release
Hydrated at
2026-06-01 01:31:18

Label at a glance#

ProductSHISEIDO BENEFIANCE WRINKLE SMOOTHING DAY
Active ingredientAVOBENZONE, HOMOSALATE, OCTINOXATE, OCTOCRYLENE, OXYBENZONE
Label structure9 sections

Indications and uses

helps prevent sunburn if used as directed with other sun protection measures (see Directions ), decreases the risk of skin cancer and early skin aging caused by the sun

Dosage and administration

For sunscreen use: apply liberally 15 minutes before sun exposure use a water resistant sunscreen if swimming or sweating reapply at least every 2 hours Sun Protection Measures . Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a broad spectrum SPF of 15 or higher and other sun protection measures including: limit time in the su...

Storage and handling

protect this product in this container from excessive heat and direct sun.

Label contents#

Full prescribing information#

SPL UNCLASSIFIED SECTION

Drug Facts

OTC - ACTIVE INGREDIENT SECTION

OTC - PURPOSE SECTION

Active ingredientsPurpose
AVOBENZONE 2.0%Sunscreen
HOMOSALATE 5.0%Sunscreen
OCTINOXATE 7.4%Sunscreen
OCTOCRYLENE 3.0%Sunscreen
OXYBENZONE 1.5%Sunscreen

Uses

INDICATIONS & USAGE SECTION

  • helps prevent sunburn
  • if used as directed with other sun protection measures (see Directions), decreases the risk of skin cancer and early skin aging caused by the sun

Warnings

WARNINGS SECTION

For external use only

OTC - DO NOT USE SECTION

Do not useon damaged or broken skin

OTC - WHEN USING SECTION

When using this productkeep out of eyes. Rinse with water to remove.

OTC - STOP USE SECTION

Stop use and ask a doctorif rash occurs

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

Keep out of reach of children.If product is swallowed, get medical help or contact a Poison Control Center right away.

Directions

DOSAGE & ADMINISTRATION SECTION

For sunscreen use:

  • apply liberally 15 minutes before sun exposure
  • use a water resistant sunscreen if swimming or sweating
  • reapply at least every 2 hours
  • Sun Protection Measures. Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a broad spectrum SPF of 15 or higher and other sun protection measures including:
    • limit time in the sun, especially from 10 a.m. – 2 p.m.
    • wear long-sleeve shirts, pants, hats, and sunglasses
  • children under 6 months: Ask a doctor

Inactive Ingredients

INACTIVE INGREDIENT SECTION

WATER•GLYCERIN•DIPROPYLENE GLYCOL•BUTYLENE GLYCOL•BEHENYL ALCOHOL•SD ALCOHOL 40-B•SILICA•DIMETHICONE•ISODODECANE•ISOHEXADECANE•SORBITOL•BEHENETH-20•MYRISTYL MYRISTATE•PHYTOSTERYL MACADAMIATE•ERYTHRITOL•XANTHAN GUM•TOCOPHERYL ACETATE•PEG/PPG-14/7 DIMETHYL ETHER•PEG/PPG-17/4 DIMETHYL ETHER•CAFFEINE•SAPINDUS MUKOROSSI PEEL EXTRACT•ANGELICA KEISKEI LEAF/STEM EXTRACT•CAMELLIA SINENSIS LEAF EXTRACT•CITRUS JUNOS SEED EXTRACT•ZIZIPHUS JUJUBA FRUIT EXTRACT•EUCHEUMA SERRA/GRATELOUPIA SPARSA/SACCHARINA ANGUSTATA/ULVA LINZA/UNDARIA PINNATIFIDA EXTRACT•CURCUMA LONGA (TURMERIC) RHIZOME EXTRACT•POLYQUATERNIUM-51•SACCHARINA ANGUSTATA/UNDARIA PINNATIFIDA EXTRACT•CHLORELLA VULGARIS EXTRACT•PPG-17•STEARYL ALCOHOL•BEHENETH-30•ALCOHOL•CARBOMER•CELLULOSE GUM•TRISODIUM EDTA•HDI/TRIMETHYLOL HEXYLLACTONE CROSSPOLYMER•SODIUM CITRATE•BHT•SODIUM METAPHOSPHATE•POTASSIUM HYDROXIDE•CITRIC ACID•TOCOPHEROL•PPG-3 DIPIVALATE•SODIUM METABISULFITE•PHENOXYETHANOL•FRAGRANCE•IRON OXIDES•

Other information

STORAGE AND HANDLING SECTION

  • protect this product in this container from excessive heat and direct sun.

Questions or comments?

OTC - QUESTIONS SECTION

Call toll free 1-800-906-7503

PRINCIPAL DISPLAY PANEL - 50 mL Jar Carton

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

SHISEIDO
GINZA TOKYO

Benefiance

Wrinkle Smoothing Day Cream

BROAD SPECTRUM
SPF 23
SUNSCREEN

ReNeura Technology+ ™

Wrinkles

50mL NET WT. 1.8 OZ.

PRINCIPAL DISPLAY PANEL - 50 mL Jar Carton
PRINCIPAL DISPLAY PANEL - 50 mL Jar Carton

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
7dea7767-9f52-b60a-5435-33cb9cc28baeProduct name420250124
6338270f-96cb-0ecb-6fbb-0a9bc78001f4Product name720250116
0ca83774-3f79-b837-5d6f-c210102f3bc8Product name620250114
41b814f3-0166-1c53-c9ef-a0794c7daf9dProduct name320221110
a590be26-846c-8659-a5a1-fb25907965dcProduct name220221110
2dc76302-91c0-4c35-ad78-99adfb049c4bProduct name120200603
e6065d4b-5ae1-476f-a40e-f2851cbb5d2bProduct name220180221
f212291f-05fe-9603-fc7e-bd73e38ce1e6Product name220161129
182f9ab4-4ab5-c449-200f-87ce2ce8e550Product name220151105
332e86c3-7875-ca6e-f934-2206d2b31996Product name120140508
56625fcc-aa34-9d30-d0e9-1c1beb37ea21Product name120140508
7dfac40f-a405-cd2e-7c06-3059ec0e1092Product name120140508
96c2be53-8e44-452d-56a2-d255b2f1af2dProduct name120140508
bf8bd5f7-495f-4022-2780-7ded7ea7ea44Product name120140508
d223c173-c39b-d764-47d4-d671d3088815Product name120140508
e01133ad-4dcd-c7f3-454b-2ff569ee160aProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
58411-439-50SHISEIDO BENEFIANCE WRINKLE SMOOTHING DAY50 mL in 1 JARCREAM503
58411-439-50SHISEIDO BENEFIANCE WRINKLE SMOOTHING DAY1 in 1 CARTONCREAM13

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 2 · 52 matching rows.

NDC Codes#

Product NDC, Package NDC table
Product NDCPackage NDC
58411-43958411-439-50

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 2 · 50 matching rows.

Name, UNII, Kind table
NameUNIIKind
WATER059QF0KO0RIACT
GLYCERINPDC6A3C0OXIACT
DIPROPYLENE GLYCOLE107L85C40IACT
BUTYLENE GLYCOL3XUS85K0RAIACT
DOCOSANOL9G1OE216XYIACT
SILICON DIOXIDEETJ7Z6XBU4IACT
DIMETHICONE92RU3N3Y1OIACT
ISODODECANEA8289P68Y2IACT
ISOHEXADECANE918X1OUF1EIACT
SORBITOL506T60A25RIACT
BEHENETH-20BJ4GP2IFLNIACT
MYRISTYL MYRISTATE4042ZC00DYIACT
ERYTHRITOLRA96B954X6IACT
XANTHAN GUMTTV12P4NEEIACT
.ALPHA.-TOCOPHEROL ACETATE, DL-WR1WPI7EW8IACT
PEG/PPG-14/7 DIMETHYL ETHER6DNW9T7YT2IACT
PEG/PPG-17/4 DIMETHYL ETHER4ET18WJG5KIACT
CAFFEINE3G6A5W338EIACT
SAPINDUS MUKOROSSI FRUIT RIND3D1P12PN9UIACT
ANGELICA KEISKEI TOPAP628M4TQOIACT
GREEN TEA LEAFW2ZU1RY8B0IACT
CITRUS JUNOS SEEDUY43O1Q45NIACT
JUJUBE FRUITG55HNL2C70IACT
TURMERIC856YO1Z64FIACT
POLYQUATERNIUM-51 (2-METHACRYLOYLOXYETHYL PHOSPHORYLCHOLINE/N-BUTYL METHACRYLATE; 3:7)EL9825H96JIACT
CHLORELLA VULGARISRYQ4R60M02IACT
PPG-17OV0Q322E0UIACT
STEARYL ALCOHOL2KR89I4H1YIACT
BEHENETH-3021Z34J9KN8IACT
ALCOHOL3K9958V90MIACT
CARBOMER HOMOPOLYMER, UNSPECIFIED TYPE0A5MM307FCIACT
CARBOXYMETHYLCELLULOSE SODIUM, UNSPECIFIEDK679OBS311IACT
EDETATE TRISODIUM420IP921MBIACT
HEXAMETHYLENE DIISOCYANATE/TRIMETHYLOL HEXYLLACTONE CROSSPOLYMERWB5K9Y35Y9IACT
SODIUM CITRATE, UNSPECIFIED FORM1Q73Q2JULRIACT
BUTYLATED HYDROXYTOLUENE1P9D0Z171KIACT
SODIUM POLYMETAPHOSPHATEP1BM4ZH95LIACT
POTASSIUM HYDROXIDEWZH3C48M4TIACT
CITRIC ACID MONOHYDRATE2968PHW8QPIACT
.ALPHA.-TOCOPHEROLH4N855PNZ1IACT

Source Document#

Source XML

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
SHISEIDO BENEFIANCE WRINKLE SMOOTHING DAYAVOBENZONE, HOMOSALATE, OCTINOXATE, OCTOCRYLENE, AND OXYBENZONESHISEIDO AMERICAS CORPORATION4bd99626-690b-49e8-8c42-a2e2dbca09bf2026-01-05WarningsExact identifier
ndc (package): 58411-439-50
ndc (product): 58411-439
ndc11 (package): 58411043950
spl id: 47a68506-6b48-cd46-e063-6294a90a3ef1
spl set id: 4bd99626-690b-49e8-8c42-a2e2dbca09bf

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.