ESTRIOL 5000 MCG 5 G- estriol 5000 mcg 5g cream

Drug Labeling and Warnings

Drug Details [pdf]

DOSAGE AND USE

Apply once or twice a day. Massage into wrists, inner arms, thighs, chest, or use as directed by your physician. Each pump is 5 g of Estriol

PURPOSE

This is a topical cream that contains bio-identical micronized USP Estriol derived from wild yam, blended moisturizing MSN, Shea Butter, Olive Oil,and Coconut Oil. When applied topically to the skin, it may help to balance your hormones and provide support for perimenopause and menopause

PREGNANT OR BREASTFEEDING

If pregnant or nursing or if you have a serious medical condition, consult a healthcare professional before using this product.

KEEP OUT OF REACH OF CHILDREN

KEEP OUT OF REACH OF CHILDREN

QUESTIONS

Contact support@wiseessentials.com

www.wiseessentials.com

REFERENCE SECTION

Medline Plus. Click here https://vsearch.nlm.nih.gov/

Medline Plus, Clinical Trials, PubMed, Biochemical Data Summary

https://clinicaltrials.gov/search?term=ESTRIOL

https://go.drugbank.com/drugs/DB04573

Report Adverse Events click here https://www.accessdata.fda.gov/scripts/medwatch/
FDA Safety Recalls Click here https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts
Presence in Breast Milk Click here https://www.ncbi.nlm.nih.gov/books/NBK501345/

Report Adverse Events click here https://www.accessdata.fda.gov/scripts/medwatch/</p> <p></p> <p>FDA Safety Recalls Click here https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts</p> <p></p> <p>Presence in Breast Milk Click here https://www.ncbi.nlm.nih.gov/books/NBK501345/</p>

Estriol 5 g 50000 mcg

Estriol 5 g 50000 mcg

WARNINGS

If pregnant or nursing or if you have a serious medical condition, consult a healthcare professional before using this product.

Discontinue use if skin irritation or red skin develops, and consult a Physician.

California Prop 65 Law requires this statement: This product contains progesterone, a chemical known only to the State of California to cause cancer.

Cease using this product and seek medical attention if skin irritation or other negative reactions occur.

INACTIVE INGREDIENTS

Purified Water, Vegetable Glycerin, (Kosher Source), Micronized Estriol USP, Caprylic/Capric Triglyceride, Aloe Vera Gel, Stearic Acid, MSM (Methylsulfonylmethane), Isopropyl Palmitate, Herbs & Blend of Essential Oils (Natural Preservative), Olive Oil, Coconut Oil, Stearyl Alcohol, Shea Butter, Carbopol® Ultrez 10,, Sunflower Lecithin

Indication and Usage Section

USES:

This is a topical cream that contains bio-identical estriol derived from wild yam. When applied to the skin it can help balance your hormones and provide temporary relief from menopausal symptoms such as hot flashes.

DIRECTIONS:

Apply once or twice a day. Massage into inner arms, thighs, chest or apply to inner forearm and rub arms together or use as directed by your Physician.

Estriol Label

Estriol

INGREDIENTS AND APPEARANCE

ESTRIOL 5000 MCG 5 G 
estriol 5000 mcg 5g cream

Product Information
Product Type	HUMAN OTC DRUG	Item Code (Source)	NDC: 87250-105
Route of Administration	TRANSDERMAL

Active Ingredient/Active Moiety
Ingredient Name	Basis of Strength	Strength
ESTRIOL (UNII: FB33469R8E) (ESTRIOL - UNII:FB33469R8E)	ESTRIOL	5 g  in 5 g

Inactive Ingredients
Ingredient Name	Strength
STEARIC ACID (UNII: 4ELV7Z65AP)
GLYCERIN (UNII: PDC6A3C0OX)
ISOPROPYL PALMITATE (UNII: 8CRQ2TH63M)
COCONUT OIL (UNII: Q9L0O73W7L)
SHEA BUTTER (UNII: K49155WL9Y)
ALOE VERA LEAF (UNII: ZY81Z83H0X)
SODIUM BICARBONATE (UNII: 8MDF5V39QO)
OLIVE OIL (UNII: 6UYK2W1W1E)
LECITHIN, SUNFLOWER (UNII: 834K0WOS5G)
ALLANTOIN (UNII: 344S277G0Z)

Packaging
#	Item Code	Package Description	Marketing Start Date	Marketing End Date
1	NDC: 87250-105-01	85 g in 1 BOTTLE, PUMP; Type 0: Not a Combination Product	04/11/2026

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
unapproved drug other		04/11/2026

Labeler - Wise Essentials LLC (080921731)