Wild Yam and Progesterone

Manufacturer
Wise Essentials LLC
Effective date
2026-04-18
Label type
HUMAN OTC DRUG LABEL
Version
1
Source
full-release
Hydrated at
2026-06-01 01:54:23

Key Label Information#

Active Ingredients And Purpose

ACTIVE INGREDIENT

Micronized Progesterone USP, (Wild Yam) 2%

PURPOSE

This is a topical cream that contains bio-identical micronized USP progesterone derived from wild yam, blended with phytoestrogens. When applied topically to the skin, it may help to balance your hormones and provide support for peri menopause and menopause.

Uses

INDICATIONS AND USAGE

USES: This is a topical cream that contains bio-identical micronized USP progesterone derived from wild yam, blended with phytoestrogens. When applied topically to the skin, it may help to balance your hormones and also to provide support for perimenopause and menopause. Apply once or twice a day. Massage into wrists, inner arms, thighs, chest, or apply or use as directed by your physician.

Warnings

PREGNANT OR BREASTFEEDING

If pregnant or nursing or if you have a serious medical condition, consult a healthcare professional before using this product.

WARNING

WARNINGS: FOR EXTERNAL COSMETIC USE ONLY. If pregnant or nursing or if you have a serious medical condition, consult a healthcare professional before using this product. Discontinue use if skin irritation or red skin develops, and consult a Physician. Do not use with any other progesterone or progestins. Do not use if the tamper-evident seal is broken or missing. California Prop 65 Law requires this statement: This product contains progesterone, a chemical known only to the State of California to cause cancer. Cease using this product and seek medical attention if skin irritation or other negative reactions occur.

Directions And Dosage

DOSAGE AND USE

Apply once or twice a day. Massage into wrists, inner arms, thighs, chest, or use as directed by your physician. Each 1/4 tsp is 20 mg of progesterone.

Other Label Information

QUESTIONS

QUESTIONS? Contact support@wiseessentials.com

INACTIVE INGREDIENTS

Wild Yam Extract, Dioscorea Villosa, Polyacrylamide/Isoparraffin, Laureth, USP Micronized Progesterone (from Wid Yam), Emulsifying Wax NF, Coco Caprylate Caprate, Radish Root Extract, Glycerin Stearate, Olive M 1000, Chaste Tree Berry Extract, Squalane Oil, Cholesterol, Jojoba Oil, Squalane Oil, Vitamins D, Cholesterol, Extracts of Dong Quai, Black Cohosh

Wild Yam and Progesterone Cream

DRUG FACTS Active Ingredient Micronized Progesterone USP (Wild Yam 2%) Uses This topical cosmetic cream contains USP progesterone derived from wild yam. Applied to the skin may help balance your hormones and provide support from peri-menopause and menopause symptoms like hot flashes. All natural with 21 mg per pump of USP progesterone. INGREDIENTS: Purified Water, Wild Yam Extract, Polyacrylamide/Isoparraffin, Laureth-7, Emulsifying Wax, USP Progesterone (From Wild Yam), Radish Root Cholesterol, Olive M 1000, Chaste Tree Berry Extract, Glycerin, Jojoba Oil, Squalane, Allantoin, D-Alpha Tocopherol, Extracts of Dong Quai, Black Cohosh, Distributed by Wise Essentials, St. Paul, MN 55116 Visit us at: www.WiseEssentials.com Please recycle. We do not test on animals. For California Residents Only: Proposition 65 WARNING. This product contains progesterone, a chemical known to the State of California to cause cancer. Warning: Always consult your healthcare provider before using especially if you are pregnant, nursing, intenting to get pregnant, taking medication or any medicial condition. Keep out of reach of children. Do not use if seal is damaged or missing. Store in cool, dry place.

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

DRUG FACTS Active Ingredient Micronized Progesterone USP (Wild Yam 2%) Uses This topical cosmetic cream contains USP progesterone derived from wild yam. Applied to the skin may help balance your hormones and provide support from peri-menopause and menopause symptoms like hot flashes. All natural with 21 mg per pump of USP progesterone. INGREDIENTS: Purified Water, Wild Yam Extract, Polyacrylamide/Isoparraffin, Laureth-7, Emulsifying Wax, USP Progesterone (From Wild Yam), Radish Root Cholesterol, Olive M 1000, Chaste Tree Berry Extract, Glycerin, Jojoba Oil, Squalane, Allantoin, D-Alpha Tocopherol, Extracts of Dong Quai, Black Cohosh, Distributed by Wise Essentials, St. Paul, MN 55116 Visit us at: www.WiseEssentials.com Please recycle. We do not test on animals. For California Residents Only: Proposition 65 WARNING. This product contains progesterone, a chemical known to the State of California to cause cancer. Warning: Always consult your healthcare provider before using especially if you are pregnant, nursing, intenting to get pregnant, taking medication or any medicial condition. Keep out of reach of children. Do not use if seal is damaged or missing. Store in cool, dry place.

Label Images#

NDC-2-92223-pump-2026--JPEG copy 2
NDC-2-92223-pump-2026--JPEG copy 2

DailyMed Pharmacologic Classes#

Class, Version, Type table
ClassVersionTypeEffective
PROGESTERONE Pharmacologic Class Indexing2Indexing - Pharmacologic Class20180813

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
b46148e2-ee15-98d5-12f0-f5ec8745f6fcProduct name320220927
76820076-f087-4073-b1d1-aa04b361335eProduct name220220921
d3229c1a-4e51-4e04-9b13-00d24fd35242Product name120200821
213f0591-95c1-b398-40b7-08b31f66b026Product name420190206
85b2d644-53b2-f2dc-4dbc-859116ce56c0Product name120140508
d048f0e3-3c40-8816-8c5c-0ca5cd189aacProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
87250-106-02Wild Yam and Progesterone85 g in 1 BOTTLE, PUMPCREAM851

Products#

NDC Codes#

Product NDC, Package NDC table
Product NDCPackage NDC
87250-10687250-106-02

Ingredients#

Complete SPL Sections#

ACTIVE INGREDIENT

OTC - ACTIVE INGREDIENT SECTION

Micronized Progesterone USP, (Wild Yam) 2%

KEEP OUT OF REACH OF CHILDREN

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

Keep out of Reach of Children.

PREGNANT OR BREASTFEEDING

OTC - PREGNANCY OR BREAST FEEDING SECTION

If pregnant or nursing or if you have a serious medical condition, consult a healthcare professional before using this product.

WARNING

WARNINGS SECTION

WARNINGS: FOR EXTERNAL COSMETIC USE ONLY. If pregnant or nursing or if you have a serious medical condition, consult a healthcare professional before using this product. Discontinue use if skin irritation or red skin develops, and consult a Physician. Do not use with any other progesterone or progestins. Do not use if the tamper-evident seal is broken or missing. California Prop 65 Law requires this statement: This product contains progesterone, a chemical known only to the State of California to cause cancer. Cease using this product and seek medical attention if skin irritation or other negative reactions occur.

DOSAGE AND USE

DOSAGE & ADMINISTRATION SECTION

Apply once or twice a day. Massage into wrists, inner arms, thighs, chest, or use as directed by your physician. Each 1/4 tsp is 20 mg of progesterone.

PURPOSE

OTC - PURPOSE SECTION

This is a topical cream that contains bio-identical micronized USP progesterone derived from wild yam, blended with phytoestrogens. When applied topically to the skin, it may help to balance your hormones and provide support for peri menopause and menopause.

INDICATIONS AND USAGE

INDICATIONS & USAGE SECTION

USES: This is a topical cream that contains bio-identical micronized USP progesterone derived from wild yam, blended with phytoestrogens. When applied topically to the skin, it may help to balance your hormones and also to provide support for perimenopause and menopause. Apply once or twice a day. Massage into wrists, inner arms, thighs, chest, or apply or use as directed by your physician.

QUESTIONS

OTC - QUESTIONS SECTION

QUESTIONS? Contact support@wiseessentials.com

SAFETY

OTHER SAFETY INFORMATION

Report Adverse Events click here https://www.accessdata.fda.gov/scripts/medwatch/ FDA Safety Recalls Click here https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts Presence in Breast Milk Click here https://www.ncbi.nlm.nih.gov/books/NBK501345/

DISCLAIMER

OTHER SAFETY INFORMATION

DISCLAIMER Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs For further information about unapproved drugs, https://www.fda.gov/drugs/enforcement-activities-fda/unapproved-drugs

RELATED RESOURCES

REFERENCES SECTION

Medline Plus. Click here https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&query=PROGESTERONE&_gl=1*f9papn*_ga*MTc2NTIwMjU3MS4xNzY1Njc2NTE5*_ga_7147EPK006*czE3NjU2NzY1MTgkbzEkZzEkdDE3NjU2NzY4NzEkajI1JGwwJGgw*_ga_P1FPTH9PL4*czE3NjU2NzY1MTgkbzEkZzEkdDE3NjU2NzY4NzEkajI1JGwwJGgw Clinical Trials.Click here https://www.clinicaltrials.gov/search?term=PROGESTERONE&viewType=Table#classicRedirect Biochemcical Date Summary. Click here. https://go.drugbank.com/drugs/DB00396

INACTIVE INGREDIENTS

INACTIVE INGREDIENT SECTION

Wild Yam Extract, Dioscorea Villosa, Polyacrylamide/Isoparraffin, Laureth, USP Micronized Progesterone (from Wid Yam), Emulsifying Wax NF, Coco Caprylate Caprate, Radish Root Extract, Glycerin Stearate, Olive M 1000, Chaste Tree Berry Extract, Squalane Oil, Cholesterol, Jojoba Oil, Squalane Oil, Vitamins D, Cholesterol, Extracts of Dong Quai, Black Cohosh

Wild Yam and Progesterone Cream

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

DRUG FACTS Active Ingredient Micronized Progesterone USP (Wild Yam 2%) Uses This topical cosmetic cream contains USP progesterone derived from wild yam. Applied to the skin may help balance your hormones and provide support from peri-menopause and menopause symptoms like hot flashes. All natural with 21 mg per pump of USP progesterone. INGREDIENTS: Purified Water, Wild Yam Extract, Polyacrylamide/Isoparraffin, Laureth-7, Emulsifying Wax, USP Progesterone (From Wild Yam), Radish Root Cholesterol, Olive M 1000, Chaste Tree Berry Extract, Glycerin, Jojoba Oil, Squalane, Allantoin, D-Alpha Tocopherol, Extracts of Dong Quai, Black Cohosh, Distributed by Wise Essentials, St. Paul, MN 55116 Visit us at: www.WiseEssentials.com Please recycle. We do not test on animals. For California Residents Only: Proposition 65 WARNING. This product contains progesterone, a chemical known to the State of California to cause cancer. Warning: Always consult your healthcare provider before using especially if you are pregnant, nursing, intenting to get pregnant, taking medication or any medicial condition. Keep out of reach of children. Do not use if seal is damaged or missing. Store in cool, dry place.

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

DRUG FACTS Active Ingredient Micronized Progesterone USP (Wild Yam 2%) Uses This topical cosmetic cream contains USP progesterone derived from wild yam. Applied to the skin may help balance your hormones and provide support from peri-menopause and menopause symptoms like hot flashes. All natural with 21 mg per pump of USP progesterone. INGREDIENTS: Purified Water, Wild Yam Extract, Polyacrylamide/Isoparraffin, Laureth-7, Emulsifying Wax, USP Progesterone (From Wild Yam), Radish Root Cholesterol, Olive M 1000, Chaste Tree Berry Extract, Glycerin, Jojoba Oil, Squalane, Allantoin, D-Alpha Tocopherol, Extracts of Dong Quai, Black Cohosh, Distributed by Wise Essentials, St. Paul, MN 55116 Visit us at: www.WiseEssentials.com Please recycle. We do not test on animals. For California Residents Only: Proposition 65 WARNING. This product contains progesterone, a chemical known to the State of California to cause cancer. Warning: Always consult your healthcare provider before using especially if you are pregnant, nursing, intenting to get pregnant, taking medication or any medicial condition. Keep out of reach of children. Do not use if seal is damaged or missing. Store in cool, dry place.

Source Document#

Source XML