Indications and uses
treats cold sores/fever blisters on the face or lips shortens healing time and duration of symptoms: tingling, pain, burning, and/or itching
treats cold sores/fever blisters on the face or lips shortens healing time and duration of symptoms: tingling, pain, burning, and/or itching
adults and children 12 years or over: wash hands before and after applying cream apply to affected area on face or lips at the first sign of cold sore/fever blister (tingle). early treatment ensures the best results rub in gently but completely use 5 times a day until healed children under 12 years : ask a doctor
store at 20°-25°C (68°-77°F). do not freeze.
Docosanol 10%
Cold sore/fever blister treatment
Allergy alert:
This product may cause a severe allergic reaction.
Syptoms may include:
If an allergic reaction occurs, stop use and seek medical help right away.
For external use only
If swallowed, get medical help or contact a Poison Control Center right away.
benzyl alcohol, light mineral oil, propylene glycol, purified water, sucrose distearate, sucrose stearate
call toll-free 1-866-547-5097 from Monday to Friday between 9:00 am to 5.00 pm
Distributed by:
One2Zee LLC,
61 Bay Hill Blvd,
Monroe Township,
NJ 08831
Active ingredient made in India
Docosanol Cream, 10% contains the only OTC medicine approved by the FDA to shorten healing time and duration of symptoms.
Retain this carton for full product uses, directions and warnings.
If you are not completely satisfied, save receipt and remaining product,and call us at 1-866-547-5097
Thank you for purchasingDocosanol Cream, 10%.We hope that since Docosanol Cream shortens the healing time of cold sores, it helps you look and feel better faster. Please follow insert directions for proper use and refer to the information below.
You are not alone
An estimated one-in-five Americans is affected by cold sores each year. Most people who experience them get two to three cold sore outbreaks each year. Just before and during an outbreak, the cold sore infection can be easily passed on to others. It is especially important to be aware of early warning signs that a cold sore is coming, and to be sure to avoid close physical contact when you have one.
Getting to the Root of the Problem
A blister, or cluster of blisters around your mouth, is caused by the cold sore virus. After the cold sore has healed, the virus stays dormant in your body but can be reactivated by everyday triggers like stress, sunlight, extreme hot or cold weather, colds and flu, lack of sleep, or menstruation.
The Sooner, the Better
A typical cold sore outbreak can last as long as seven to ten days. The sooner you begin using Docosanol Cream, 10%, the more effective the medicine will be. So for best results, use Docosanol Cream, 10% at the very start of the cold sore - when you feel the first sign of the tingle, redness, bump or itch.
Docosanol Cream, 10% is different from other over-the-counter cold sore products. Only Docosanol Cream, 10% contains 10% docosanol, which helps to shorten the healing time of cold sores and the duration of symptoms including tingling, pain, itching and burning.
For Pump Bottle
How to use your Docosanol Cream, 10% Pump
- For Adults and children 12 years and over can use Docosanol Cream, 10%.
- Docosanol Cream, 10% should be used five times a day until the cold sore is healed. Apply it directly to the cold sore at the first sign of a tingle, redness, bump or itch for best results.
- If you wish, you can apply cosmetics such as lipstick over Docosanol Cream, 10%. However, use a separate applicator, like a cotton swab, to apply cosmetics over an unhealed cold sore to avoid spreading the infection. For best results, remove any cosmetics prior to applying Docosanol Cream, 10%.
Press Pump completely about 6-8 times to get first dose.

STEP 1 – Wash your hands before and after treating the cold sore.
STEP 2 – Remove cap and press pump firmly. When first used, expect to press pump completely about 6-8 times before obtaining first dose.
STEP 3 – Rub in gently but completely 5 times a day until healed for maximum of 10 days.
STEP 4 – Place cap back on pump after each use.
For Tube
Who can use Docosanol Cream, 10%?
Adults and children 12 years and over can use Docosanol Cream, 10%.
How often can I apply Docosanol Cream, 10%?
Docosanol Cream, 10% should be used five times a day until the cold sore is healed. Apply it directly to the cold sore at the first sign of a tingle, redness, bump or itch for best results.
Can I apply cosmetics on top of Docosanol Cream, 10%?
Yes, cosmetics such as lipstick may be applied over Docosanol Cream, 10%. However, use a separate applicator, like a cotton swab, to apply cosmetics over an unhealed cold sore to avoid spreading the infection. For best results, remove any cosmetics prior to applying Docosanol Cream, 10%.
For Tube - Carton Label
NDC 84725-001-01
KLM
Docosanol Cream, 10%
COLD SORE/FEVER BLISTER TREATMENT
Shortens Healing Time and Duration of Symptoms
‣Tingling ‣Pain ‣Burning ‣Itching
The only FDA Approved Medicine to SHORTEN HEALING TIME*
NET WT 2 g (0.07oz)
For Pump Bottle - Carton Label
NDC 84725- 001-02
KLM
Docosanol Cream, 10%
COLD SORE/FEVER BLISTER TREATMENT
Shortens Healing Time and Duration of Symptoms
‣Tingling ‣Pain ‣Burning ‣Itching
Convenient PORTABLE Pump
The only FDA Approved Medicine to SHORTEN HEALING TIME*
NET WT 2 g (0.07oz)

For Twin Pack - Tube Carton Label
NDC 84725- 001-09
KLM
Docosanol Cream, 10%
COLD SORE/FEVER BLISTER TREATMENT
Shortens Healing Time and Duration of Symptoms
‣Tingling ‣Pain ‣Burning ‣Itching
Twin Pack
The only FDA Approved Medicine to SHORTEN HEALING TIME*
2 TUBES OF 2 g (0.07 oz)
TOTAL NET WT 4 g (0.14 oz)
Every source-derived product name is available through these pages.
| Product NDC | Package NDC |
|---|---|
| 84725-001 | 84725-001-01, 84725-001-02, 84725-001-09 |
Every source-derived ingredient row is available through these pages.
| Name | UNII | Kind |
|---|---|---|
| DOCOSANOL | 9G1OE216XY | ACTIB |
| BENZYL ALCOHOL | LKG8494WBH | IACT |
| LIGHT MINERAL OIL | N6K5787QVP | IACT |
| PROPYLENE GLYCOL | 6DC9Q167V3 | IACT |
| WATER | 059QF0KO0R | IACT |
| SUCROSE DISTEARATE | 33X4X4B90S | IACT |
| SUCROSE STEARATE | 274KW0O50M | IACT |
| Version | Effective date | Source | Hydrated |
|---|---|---|---|
| 10 | 2026-09-08 | daily-update | 2026-09-11 03:02:47 |
| 3 | 2026-08-18 | daily-update | 2026-09-08 02:02:28 |
| 2 | 2024-09-25 | daily-update | 2026-08-04 03:32:57 |
All distinct exact application/product contexts derived from this label’s complete NDC list are paginated below.
| Application-product | Trade name | Ingredient | Strength | Dosage form / route | TE codes | RLD / RS | Approval date |
|---|---|---|---|---|---|---|---|
| A220017-001 | DOCOSANOL | DOCOSANOL | 10% | CREAM / TOPICAL | 2026-07-31 |
Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.
| Captured | Edition | Application-product | Trade name | Strength | Dosage form / route | Product TE source text | RLD / RS | Approval date | Source SHA-256 |
|---|---|---|---|---|---|---|---|---|---|
| 2026-09-14 22:38:34 | 2026-08 | A220017-001 | DOCOSANOL | 10% | CREAM / TOPICAL | 2026-07-31 | 84e616aacf4f… | ||
| 2026-08-18 06:07:40 | 2026-07 | A220017-001 | DOCOSANOL | 10% | CREAM / TOPICAL | 2026-07-31 | caaa826d4ba7… |
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| Docosanol | DOCOSANOL | KLM Laboratories Private Limited | 5783edbf-2ce6-4b7e-8df3-2e421c63d0e8 | 2026-09-08 | Warnings | 84725-001-02 84725-001-01 84725-001 84725000101 84725000102 5783edbf-2ce6-4b7e-8df3-2e421c63d0e8 |
Adverse event summaries are temporarily unavailable. Other product information remains available.