adults and children 2 years of age and older: brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or doctor. children under 6 years of age: instruct in good brushing and rinsing habits (to minimize swallowing). supervise children as necessary until capable of using without supervision. do not swallow children under 2 years of age: consult a dentist or doctor
Sodium fluoride 0.24% (0.13% w/v fluoride ion)
Anticavity
Aids in the prevention of dental decay.
Keep out of reach of children under 6 years of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away.
adults and children 2 years of age and older: brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or doctor.
children under 6 years of age:
children under 2 years of age:
consult a dentist or doctor
water, hydrated silica, stabilized chlorine dioxide, sarkosyl (coconut derived), disodium hydrogen phosphate, cellulose gum, titanium dioxide, peppermint oil, sodium dihydrogen phosphate, sucralose, menthol crystals
Use of stabilized chlorine dioxide is protected under U.S. & foregin patents-see CloSYS.com/patents
Call 1-800-643-3337
Closys®
Anticavity Fluoride Toothpaste
SULFATE-FREE
NEW LOOK!
A CLEANER MOUTH
A HEALTHIER YOU®
CLoSYS ®
Anticavity Fluoride Toothpaste
SENSITIVE
TOOTHPASTE
WITH FLUORIDE
NON-IRRITATING
SULFATE-FREE
HELPS REBUILD WEAKEND
TOOTH ENAMEL
Protects Against
Cavities
Freshens Breath
Non-Irritating
Formula
Gentle Mint
7oz (196g)
NON-IRRITATING
SULFATE-FREE
pH balanced
Fights
Cavities
Strengthens
Enamel
Closys®
Anticavity Fluoride Toothpaste
SENSITIVE TOOTHPASTE
WITH FLUORIDE
NON-IRRITATING SULFATE-FREE
HELPS REBUILD WEAKEND TOOTH ENAMEL
Protects Against Cavities
Freshens Breath
Non-Irritating Formula
Gentle Mint 7oz (196g)
Closys®
Anticavity Fluoride Toothpaste
SULFATE-FREE
NEW LOOK!
A CLEANER MOUTH
A HEALTHIER YOU®
CLoSYS ®
Anticavity Fluoride Toothpaste
SENSITIVE
TOOTHPASTE
WITH FLUORIDE
NON-IRRITATING
SULFATE-FREE
HELPS REBUILD WEAKEND
TOOTH ENAMEL
Protects Against
Cavities
Freshens Breath
Non-Irritating
Formula
Gentle Mint
3.4oz (96g)
NON-IRRITATING
SULFATE-FREE
pH balanced
Fights
Cavities
Strengthens
Enamel
Closys®
Anticavity Fluoride Toothpaste
SENSITIVE TOOTHPASTE
WITH FLUORIDE
NON-IRRITATING SULFATE-FREE
HELPS REBUILD WEAKEND TOOTH ENAMEL
Protects Against Cavities
Freshens Breath
Non-Irritating Formula
Gentle Mint 3.4oz (96g)
| RxCUI | RxNorm string | TTY | SPL version |
|---|---|---|---|
| 416783 | sodium fluoride 0.24 % Toothpaste | PSN | 11 |
| 416783 | sodium fluoride 0.0024 MG/MG Toothpaste | SCD | 11 |
| 416783 | sodium fluoride 0.24 % (fluoride ion 0.13 % ) Toothpaste | SY | 11 |
| 416783 | sodium fluoride 0.24 % (fluoride ion 0.14 % ) Toothpaste | SY | 11 |
| 416783 | sodium fluoride 0.24 % (fluoride ion 0.15 % ) Toothpaste | SY | 11 |
| Product concept | Relation | Version | Effective |
|---|---|---|---|
| 726062af-1135-4707-a1d7-57256991bbf9 | Product name | 2 | 20250226 |
| 19c71a3d-ed9c-166b-a7e5-38c250c35631 | Product name | 1 | 20140508 |
| Package NDC | Product | Description | Form | Quantity | Strength | SPL version |
|---|---|---|---|---|---|---|
| 58578-0749-1 | CloSYS | 1 in 1 BOX | PASTE, DENTIFRICE | 1 | 11 | |
| 58578-0749-1 | CloSYS | 96 g in 1 TUBE | PASTE, DENTIFRICE | 96 | 11 | |
| 58578-0749-2 | CloSYS | 1 in 1 BOX | PASTE, DENTIFRICE | 1 | 11 | |
| 58578-0749-2 | CloSYS | 198 g in 1 TUBE | PASTE, DENTIFRICE | 198 | 11 | |
| 58578-0749-3 | CloSYS | 21 g in 1 TUBE | PASTE, DENTIFRICE | 21 | 11 | |
| 58578-0749-3 | CloSYS | 1 in 1 BOX | PASTE, DENTIFRICE | 1 | 11 | |
| 58578-0749-4 | CloSYS | 198 g in 1 TUBE | PASTE, DENTIFRICE | 198 | 11 | |
| 58578-0749-4 | CloSYS | 2 in 1 PACKAGE | PASTE, DENTIFRICE | 2 | 11 |
Every source-derived product name is available through these pages.
| Product NDC | Package NDC |
|---|---|
| 58578-0749 | 58578-0749-1, 58578-0749-2, 58578-0749-3, 58578-0749-4 |
Every source-derived ingredient row is available through these pages.
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| CloSYS | SODIUM FLUORIDE | Rowpar Pharmaceuticals, Inc. | 5f87abb7-0e9d-6369-e053-2a91aa0a2411 | 2026-03-31 | Warnings | 58578-0749-2 58578-0749-4 58578-0749-3 58578-0749-1 58578-0749 58578074901 58578074903 58578074902 58578074904 4aab2169-2fe1-4d9b-94a0-45724392e6bc 5f87abb7-0e9d-6369-e053-2a91aa0a2411 |
Adverse event summaries are temporarily unavailable. Other product information remains available.