ISTINA NOURISHING AGE-DEFYING HYDRATION CREAM- niacinamide cream

ISTINA Nourishing Age-defying Hydration Cream by

Drug Labeling and Warnings

ISTINA Nourishing Age-defying Hydration Cream by is a Otc medication manufactured, distributed, or labeled by NBM INC.. Drug facts, warnings, and ingredients follow.

Drug Details [pdf]

Active Ingredients

Adenosine 0.04%
Niacinamide 2.00%

Purpose

Skin protectant

Uses

• Helps prevent and temporarily protects chapped or cracked skin.

When using this product

• do not get into eyes.

Warnings

For external use only.

Stop use and ask a doctor if

• condition worsens
• symptoms last more than 7 days or clear up and occurs again within a few days
  

Keep out of reach of children

If product is swallowed, get medical help or contact a Poison Control Center right away.

Directions

Apply as needed.

After cleansing and toning your face, apply adequate amount of cream all over the face and neck area and massage gently with fingertips.

Inactive ingredients

WATER, BUTYLENE GLYCOL, MEADOWFOAM SEED OIL, GLYCERIN, TRIMETHYLOLPROPANE TRICAPRYLATE/TRICAPRATE, CETEARYL ALCOHOL, POLYGLUTAMIC ACID, CYCLOMETHICONE 5, MEDIUM-CHAIN TRIGLYCERIDES, STEARETH-20, CETEARYL OLIVATE, TRIMETHYLPENTANEDIOL/ADIPIC ACID/GLYCERIN CROSSPOLYMER, N-ACETYLGLUCOSAMINE, STEARETH-2 MACADAMIA OIL, LANOLIN, SORBITAN OLIVATE, CYCLOMETHICONE 6, SODIUM ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER, STEARIC ACID, CHOLESTEROL, BEMISIOSE, HYALURONATE SODIUM, BETAINE, FRAGRANCE, HYDROLYZED SILK, DIMETHICONE/VINYL DIMETHICONE CROSSPOLYMER, HYDROGENATED LECITHIN, HYDROGENATED POLYDECENE, HYDROGENATED STARCH HYDROLYSATE,1,2-HEXANEDIOL, TOCOPHERYL ACETATE, ALCOHOL, CAPRYLYL GLYCOL, DIMETHICONE CROSSPOLYMER, CHAMAECYPARIS OBTUSA WATER, HAMAMELIS VIRGINIANA (WITCH HAZEL) EXTRACT, CITRUS GRANDIS (GRAPEFRUIT) SEED EXTRACT, IMPERATA CYLINDRICA ROOT EXTRACT, XANTHAN GUM, VISCUM ALBUM (MISTLETOE) LEAF EXTRACT, ADENOSINE, VISCUM ALBUM (MISTLETOE) EXTRACT, LAURETH-8, ARGANIA SPINOSA KERNEL EXTRACT, LACTOBACILLUS/SOYBEAN FERMENT EXTRACT, BAMBUSA TEXTILIS STEM EXTRACT, PINUS PALUSTRIS LEAF EXTRACT, LECITHIN, PEG-8, CARBOMER, SODIUM COCOYL GLUTAMATE, MANNITOL, CERAMIDE NP, TOCOPHEROL, SODIUM CHLORIDE, ROYAL JELLY EXTRACT, RICE SH-OLIGOPEPTIDE-1, RICE SH-POLYPEPTIDE-1, DISODIUM PHOSPHATE, POTASSIUM PHOSPHATE, POTASSIUM CHLORIDE, SODIUM PHOSPHATE, FRAGRANCE

Other information

Protect this product from excessive heat and direct sun.

Questions or Comments?

Call toll free 1-800-311-6680

PRINCIPAL DISPLAY PANEL

INGREDIENTS AND APPEARANCE

ISTINA NOURISHING AGE-DEFYING HYDRATION CREAM 
niacinamide cream

Product Information
Product Type	HUMAN OTC DRUG	Item Code (Source)	NDC: 71698-101
Route of Administration	TOPICAL

Active Ingredient/Active Moiety
Ingredient Name	Basis of Strength	Strength
NIACINAMIDE (UNII: 25X51I8RD4) (NIACINAMIDE - UNII:25X51I8RD4)	NIACINAMIDE	2 g  in 1 mL

Inactive Ingredients
Ingredient Name	Strength
N-ACETYLGLUCOSAMINE (UNII: V956696549)
TOCOPHEROL (UNII: R0ZB2556P8)
VISCUM ALBUM LEAF (UNII: GN8217WQOV)
XANTHAN GUM (UNII: TTV12P4NEE)
DIMETHICONE CROSSPOLYMER (450000 MPA.S AT 12% IN CYCLOPENTASILOXANE) (UNII: UF7620L1W6)
DIMETHICONE/VINYL DIMETHICONE CROSSPOLYMER (SOFT PARTICLE) (UNII: 9E4CO0W6C5)
HYDROGENATED POLYDECENE (550 MW) (UNII: U333RI6EB7)
IMPERATA CYLINDRICA ROOT (UNII: VYT2JA85NH)
LANOLIN (UNII: 7EV65EAW6H)
MACADAMIA OIL (UNII: 515610SU8C)
SODIUM CHLORIDE (UNII: 451W47IQ8X)
SODIUM PHOSPHATE (UNII: SE337SVY37)
ADENOSINE (UNII: K72T3FS567)
ALCOHOL (UNII: 3K9958V90M)
MANNITOL (UNII: 3OWL53L36A)
CARBOMER 940 (UNII: 4Q93RCW27E)
BUTYLENE GLYCOL (UNII: 3XUS85K0RA)
WATER (UNII: 059QF0KO0R)
PEG/PPG-17/6 COPOLYMER (UNII: P5QZM4T259)
GLYCYRRHIZINATE DIPOTASSIUM (UNII: CA2Y0FE3FX)
EDETATE DISODIUM (UNII: 7FLD91C86K)
PINUS PALUSTRIS LEAF (UNII: OT6R5143A1)
HYALURONATE SODIUM (UNII: YSE9PPT4TH)
CHOLESTEROL (UNII: 97C5T2UQ7J)
1,2-HEXANEDIOL (UNII: TR046Y3K1G)
CITRUS MAXIMA SEED (UNII: 083X55C543)
BAMBUSA TEXTILIS STEM (UNII: 7L05M929Y1)
LAMINARIA DIGITATA (UNII: 15E7C67EE8)
SODIUM PHOSPHATE, DIBASIC, ANHYDROUS (UNII: 22ADO53M6F)
POTASSIUM PHOSPHATE, MONOBASIC (UNII: 4J9FJ0HL51)
POTASSIUM CHLORIDE (UNII: 660YQ98I10)
CHAMAECYPARIS OBTUSA WOOD OIL (UNII: P2OMP71Y62)
SODIUM ACRYLATE/SODIUM ACRYLOYLDIMETHYLTAURATE COPOLYMER (4000000 MW) (UNII: 1DXE3F3OZX)
SODIUM COCOYL GLUTAMATE (UNII: BMT4RCZ3HG)
STEARIC ACID (UNII: 4ELV7Z65AP)
ALPHA-TOCOPHEROL ACETATE (UNII: 9E8X80D2L0)
TRIMETHYLOLPROPANE TRICAPRYLATE/TRICAPRATE (UNII: N1TRQ06KVJ)
VISCUM ALBUM FRUITING TOP (UNII: BK9092J5MP)
BETAINE (UNII: 3SCV180C9W)
CAPRYLYL GLYCOL (UNII: 00YIU5438U)
CETEARYL OLIVATE (UNII: 58B69Q84JO)
CETOSTEARYL ALCOHOL (UNII: 2DMT128M1S)
CYCLOMETHICONE 5 (UNII: 0THT5PCI0R)
CYCLOMETHICONE 6 (UNII: XHK3U310BA)
HAMAMELIS VIRGINIANA TOP (UNII: UDA30A2JJY)
ARGANIA SPINOSA SEED (UNII: 8H7X7XB54H)
HYDROGENATED STARCH HYDROLYSATE (UNII: 27F77DSJ5V)
LAURETH-8 (UNII: QU7U88D04I)
MEADOWFOAM SEED OIL (UNII: 412ZHA4T4Y)
MEDIUM-CHAIN TRIGLYCERIDES (UNII: C9H2L21V7U)
SORBITAN OLIVATE (UNII: MDL271E3GR)
STEARETH-2 (UNII: V56DFE46J5)
STEARETH-20 (UNII: L0Q8IK9E08)
ROYAL JELLY (UNII: L497I37F0C)
SILK, BASE HYDROLYZED (1000 MW) (UNII: UMQ31C11AY)
BEMISIOSE (UNII: 76B4LOB2YC)
CERAMIDE NP (UNII: 4370DF050B)

Packaging
#	Item Code	Package Description	Marketing Start Date	Marketing End Date
1	NDC: 71698-101-01	50 mL in 1 BOTTLE, PUMP; Type 0: Not a Combination Product	10/31/2017

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
unapproved drug other		10/31/2017

Labeler - NBM INC. (688299471)