Head and Shoulders

Manufacturer: The Procter & Gamble Manufacturing Company
Effective date: 2026-02-18
Label type: HUMAN OTC DRUG LABEL
Version: 13
Source: full-release
Hydrated at: 2026-06-01 01:46:29

Label at a glance#

ProductHead and Shoulders Smooth and Silky 2in1

Active ingredientPYRITHIONE ZINC

Label structure10 sections

Indications and uses

helps prevent recurrence of flaking and itching associated with dandruff.

Dosage and administration

for best results use at least twice a week or as directed by a doctor. for maximum dandruff control, use every time you shampoo. shake before use. wet hair, massage onto scalp, rinse, repeat if desired.

Contacts and useful links#

PhoneLabel contact1-800-723-9569

Label contents#

Full prescribing information#

SPL UNCLASSIFIED SECTION

Drug Facts

Active ingredient

OTC - ACTIVE INGREDIENT SECTION

Pyrithione zinc 1%

Purpose

OTC - PURPOSE SECTION

Anti-dandruff

Uses

INDICATIONS & USAGE SECTION

helps prevent recurrence of flaking and itching associated with dandruff.

Warnings

WARNINGS SECTION

For external use only.

When using this product

OTC - WHEN USING SECTION

avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water.

Stop use and ask a doctor if

OTC - STOP USE SECTION

condition worsens or does not improve after regular use of this product as directed.

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

Keep this and all drugs out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Directions

DOSAGE & ADMINISTRATION SECTION

for best results use at least twice a week or as directed by a doctor.
for maximum dandruff control, use every time you shampoo.
shake before use.
wet hair, massage onto scalp, rinse, repeat if desired.

Inactive ingredients

INACTIVE INGREDIENT SECTION

Water, sodium lauryl sulfate, glycol distearate, zinc carbonate, sodium chloride, fragrance, cocamidopropyl betaine, sodium xylenesulfonate, dimethicone, sodium benzoate, guar hydroxypropyltrimonium chloride, sodium laureth sulfate, magnesium carbonate hydroxide, niacinamide, methylchloroisothiazolinone, methylisothiazolinone

Questions (or comments)?

OTC - QUESTIONS SECTION

1-800-723-9569

SPL UNCLASSIFIED SECTION

Dist. by PROCTER & GAMBLE,
CINCINNATI, OH 45202

PRINCIPAL DISPLAY PANEL - 1.18 L Bottle Label

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

head &
shoulders _®

pyrithione zinc dandruff

shampoo + conditioner

SMOOTH & SILKY

2in1

24 hour frizz control

Health scalp + hair

CLINICALLY PROVEN
UP TO 100%
DANDRUFF PROTECTION

40 FL OZ (1.18 L)
HS

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	SPL version
1043244	head & shoulders 1 % Medicated Shampoo	PSN	13
209884	zinc pyrithione 1 % Medicated Shampoo	PSN	13
1043244	zinc pyrithione 10 MG/ML Medicated Shampoo [Head & Shoulders]	SBD	13
209884	zinc pyrithione 10 MG/ML Medicated Shampoo	SCD	13
1043244	Head & Shoulders 1 % Medicated Shampoo	SY	13
1043244	Head & Shoulders 10 MG/ML Medicated Shampoo	SY	13
209884	zinc pyrithione 1 % Medicated Conditioner	SY	13
209884	zinc pyrithione 1 % Medicated Shampoo	SY	13

Product Linked Resources#

Resource, Code type, Value table
Resource	Code type	Value	Equivalent identifiers	Source image
Data code	Data Matrix	21470005		HS.jpg

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
37000-095-01	Head and ShouldersSmooth and Silky 2in1	930 mL in 1 BOTTLE, PUMP	LOTION/SHAMPOO	930	13
37000-095-01	Head and ShouldersSmooth and Silky 2in1	2 in 1 CELLO PACK	LOTION/SHAMPOO	2	13
37000-095-12	Head and ShouldersSmooth and Silky 2in1	1280 mL in 1 BOTTLE, PUMP	LOTION/SHAMPOO	1280	13
37000-095-13	Head and ShouldersSmooth and Silky 2in1	1280 mL in 1 BOTTLE, PLASTIC	LOTION/SHAMPOO	1280	13
37000-095-20	Head and ShouldersSmooth and Silky 2in1	200 mL in 1 BOTTLE, PLASTIC	LOTION/SHAMPOO	200	13
37000-095-25	Head and ShouldersSmooth and Silky 2in1	250 mL in 1 BOTTLE, PLASTIC	LOTION/SHAMPOO	250	13
37000-095-37	Head and ShouldersSmooth and Silky 2in1	370 mL in 1 BOTTLE, PLASTIC	LOTION/SHAMPOO	370	13
37000-095-38	Head and ShouldersSmooth and Silky 2in1	380 mL in 1 BOTTLE, PLASTIC	LOTION/SHAMPOO	380	13
37000-095-40	Head and ShouldersSmooth and Silky 2in1	400 mL in 1 BOTTLE, PLASTIC	LOTION/SHAMPOO	400	13
37000-095-61	Head and ShouldersSmooth and Silky 2in1	613 mL in 1 BOTTLE, PLASTIC	LOTION/SHAMPOO	613	13
37000-095-65	Head and ShouldersSmooth and Silky 2in1	650 mL in 1 BOTTLE, PLASTIC	LOTION/SHAMPOO	650	13
37000-095-70	Head and ShouldersSmooth and Silky 2in1	700 mL in 1 BOTTLE, PLASTIC	LOTION/SHAMPOO	700	13
37000-095-83	Head and ShouldersSmooth and Silky 2in1	835 mL in 1 BOTTLE, PUMP	LOTION/SHAMPOO	835	13
37000-095-93	Head and ShouldersSmooth and Silky 2in1	930 mL in 1 BOTTLE, PUMP	LOTION/SHAMPOO	930	13
37000-095-95	Head and ShouldersSmooth and Silky 2in1	950 mL in 1 BOTTLE, PUMP	LOTION/SHAMPOO	950	13

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	SPL version
Pyrithione Zinc	ACTIVE INGREDIENT	R953O2RHZ5	2
Pyrithione Zinc	ACTIVE MOIETY	R953O2RHZ5	2
benzyl alcohol	INACTIVE INGREDIENT	LKG8494WBH	2
cetyl alcohol	INACTIVE INGREDIENT	936JST6JCN	2
Coco Monoethanolamide	INACTIVE INGREDIENT	C80684146D	2
dimethicone	INACTIVE INGREDIENT	92RU3N3Y1O	2
glycol distearate	INACTIVE INGREDIENT	13W7MDN21W	2
magnesium carbonate hydroxide	INACTIVE INGREDIENT	YQO029V1L4	2
magnesium sulfate	INACTIVE INGREDIENT	DE08037SAB	2
methylchloroisothiazolinone	INACTIVE INGREDIENT	DEL7T5QRPN	2
methylisothiazolinone	INACTIVE INGREDIENT	229D0E1QFA	2
sodium benzoate	INACTIVE INGREDIENT	OJ245FE5EU	2
sodium chloride	INACTIVE INGREDIENT	451W47IQ8X	2
sodium laureth-3 sulfate	INACTIVE INGREDIENT	BPV390UAP0	2
sodium lauryl sulfate	INACTIVE INGREDIENT	368GB5141J	2
sodium xylenesulfonate	INACTIVE INGREDIENT	G4LZF950UR	2
Water	INACTIVE INGREDIENT	059QF0KO0R	2
zinc carbonate	INACTIVE INGREDIENT	EQR32Y7H0M	2

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 16 matching rows.

Head and Shoulders Smooth and Silky 2in1
Pyrithione Zinc
COCAMIDOPROPYL BETAINE
WATER
SODIUM LAURYL SULFATE
DIMETHICONE
ZINC CARBONATE
GLYCOL DISTEARATE
SODIUM XYLENESULFONATE
GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE (1.7 SUBSTITUENTS PER SACCHARIDE)
SODIUM BENZOATE
MAGNESIUM CARBONATE HYDROXIDE
METHYLCHLOROISOTHIAZOLINONE
METHYLISOTHIAZOLINONE
SODIUM CHLORIDE
NIACINAMIDE

NDC Codes#

Product NDC, Package NDC table
Product NDC	Package NDC
37000-095	37000-095-20, 37000-095-70, 37000-095-40, 37000-095-25, 37000-095-95, 37000-095-38, 37000-095-65, 37000-095-93, 37000-095-12, 37000-095-37, 37000-095-61, 37000-095-83, 37000-095-01, 37000-095-13

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 15 matching rows.

Name, UNII, Kind table
Name	UNII	Kind
COCAMIDOPROPYL BETAINE	5OCF3O11KX	IACT
WATER	059QF0KO0R	IACT
SODIUM LAURYL SULFATE	368GB5141J	IACT
DIMETHICONE	92RU3N3Y1O	IACT
ZINC CARBONATE	EQR32Y7H0M	IACT
GLYCOL DISTEARATE	13W7MDN21W	IACT
SODIUM XYLENESULFONATE	G4LZF950UR	IACT
GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE (1.7 SUBSTITUENTS PER SACCHARIDE)	B16G315W7A	IACT
SODIUM BENZOATE	OJ245FE5EU	IACT
MAGNESIUM CARBONATE HYDROXIDE	YQO029V1L4	IACT
METHYLCHLOROISOTHIAZOLINONE	DEL7T5QRPN	IACT
METHYLISOTHIAZOLINONE	229D0E1QFA	IACT
PYRITHIONE ZINC	R953O2RHZ5	ACTIB
SODIUM CHLORIDE	451W47IQ8X	IACT
NIACINAMIDE	25X51I8RD4	IACT

Source Document#

Source XML

Inactive ingredient matches#

Inactive Ingredient Database values describe FDA-listed use contexts. The match method and ambiguity count are shown because ingredient names, routes, and dosage forms are not always unique. Browse recovered IID releases and source provenance.

Inactive ingredient links page 1 of 12 · 675 matching rows.

DailyMed ingredient, IID ingredient, UNII table
DailyMed ingredient	IID ingredient	UNII	Dosage form / route	Potency	Maximum daily exposure	Match
magnesium sulfate	MAGNESIUM SULFATE	DE08037SAB	SOAP / TOPICAL	0.2 %w/w		Exact identifier — unii+route 15 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	SUSPENSION/ DROPS / TOPICAL	0.23 %w/v		Exact identifier — unii+route 165 equally ranked IID candidates
benzyl alcohol	BENZYL ALCOHOL	LKG8494WBH	OINTMENT / TOPICAL	2.2 %w/w		Exact identifier — unii+route 105 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	SPRAY / TOPICAL		7 mg	Exact identifier — unii+route 120 equally ranked IID candidates
sodium benzoate	SODIUM BENZOATE	OJ245FE5EU	CREAM / TOPICAL	0.2 %w/w		Exact identifier — unii+route 75 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	SOAP / TOPICAL	1.26 %w/w		Exact identifier — unii+route 165 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	LOTION / TOPICAL		111 mg	Exact identifier — unii+route 120 equally ranked IID candidates
magnesium sulfate	MAGNESIUM SULFATE	DE08037SAB	SOAP / TOPICAL	0.2 %w/w		Exact identifier — unii+route 15 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	CREAM / TOPICAL		214 mg	Exact identifier — unii+route 120 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	SYSTEM / TOPICAL	3.1 mg		Exact identifier — unii+route 165 equally ranked IID candidates
magnesium sulfate	MAGNESIUM SULFATE	DE08037SAB	SOAP / TOPICAL	0.2 %w/w		Exact identifier — unii+route 15 equally ranked IID candidates
sodium laureth-3 sulfate	SODIUM LAURETH-3 SULFATE	BPV390UAP0	CREAM / TOPICAL	NA		Exact identifier — unii+route 45 equally ranked IID candidates
cetyl alcohol	CETYL ALCOHOL	936JST6JCN	CREAM / TOPICAL		1280 mg	Exact identifier — unii+route 120 equally ranked IID candidates
sodium laureth-3 sulfate	SODIUM LAURETH-3 SULFATE	BPV390UAP0	SPRAY / TOPICAL	0.1 %w/w		Exact identifier — unii+route 45 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	CREAM / TOPICAL	0.4 %w/w		Exact identifier — unii+route 165 equally ranked IID candidates
benzyl alcohol	BENZYL ALCOHOL	LKG8494WBH	SHAMPOO / TOPICAL	1.25 %w/w		Exact identifier — unii+route 105 equally ranked IID candidates
benzyl alcohol	BENZYL ALCOHOL	LKG8494WBH	SHAMPOO / TOPICAL	1.25 %w/w		Exact identifier — unii+route 105 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	SHAMPOO / TOPICAL	65 %w/w		Exact identifier — unii+route 120 equally ranked IID candidates
benzyl alcohol	BENZYL ALCOHOL	LKG8494WBH	GEL / TOPICAL		185 mg	Exact identifier — unii+route 105 equally ranked IID candidates
cetyl alcohol	CETYL ALCOHOL	936JST6JCN	SUSPENSION / TOPICAL	2.01 %w/w		Exact identifier — unii+route 120 equally ranked IID candidates
cetyl alcohol	CETYL ALCOHOL	936JST6JCN	CREAM / TOPICAL		1280 mg	Exact identifier — unii+route 120 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	SPRAY / TOPICAL		7 mg	Exact identifier — unii+route 120 equally ranked IID candidates
sodium benzoate	SODIUM BENZOATE	OJ245FE5EU	GEL / TOPICAL		5 mg	Exact identifier — unii+route 75 equally ranked IID candidates
cetyl alcohol	CETYL ALCOHOL	936JST6JCN	CREAM / TOPICAL		1280 mg	Exact identifier — unii+route 120 equally ranked IID candidates
sodium laureth-3 sulfate	SODIUM LAURETH-3 SULFATE	BPV390UAP0	SPRAY / TOPICAL	0.1 %w/w		Exact identifier — unii+route 45 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	SHAMPOO / TOPICAL	65 %w/w		Exact identifier — unii+route 120 equally ranked IID candidates
sodium laureth-3 sulfate	SODIUM LAURETH-3 SULFATE	BPV390UAP0	CREAM / TOPICAL	NA		Exact identifier — unii+route 45 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	SOLUTION / TOPICAL		210 mg	Exact identifier — unii+route 165 equally ranked IID candidates
sodium benzoate	SODIUM BENZOATE	OJ245FE5EU	CREAM / TOPICAL	0.2 %w/w		Exact identifier — unii+route 75 equally ranked IID candidates
sodium benzoate	SODIUM BENZOATE	OJ245FE5EU	CREAM / TOPICAL	0.2 %w/w		Exact identifier — unii+route 75 equally ranked IID candidates
benzyl alcohol	BENZYL ALCOHOL	LKG8494WBH	SOLUTION / TOPICAL	2 %w/w		Exact identifier — unii+route 105 equally ranked IID candidates
Coco Monoethanolamide	COCO MONOETHANOLAMIDE	C80684146D	SHAMPOO / TOPICAL	4 %w/w		Exact identifier — unii+route 15 equally ranked IID candidates
cetyl alcohol	CETYL ALCOHOL	936JST6JCN	AEROSOL / TOPICAL	1.16 %w/w		Exact identifier — unii+route 120 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	OINTMENT / TOPICAL		14 mg	Exact identifier — unii+route 120 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	SUSPENSION/ DROPS / TOPICAL	0.23 %w/v		Exact identifier — unii+route 165 equally ranked IID candidates
benzyl alcohol	BENZYL ALCOHOL	LKG8494WBH	OINTMENT / TOPICAL	2.2 %w/w		Exact identifier — unii+route 105 equally ranked IID candidates
cetyl alcohol	CETYL ALCOHOL	936JST6JCN	CREAM / TOPICAL		1280 mg	Exact identifier — unii+route 120 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	GEL / TOPICAL	0.18 %w/w		Exact identifier — unii+route 165 equally ranked IID candidates
cetyl alcohol	CETYL ALCOHOL	936JST6JCN	EMULSION / TOPICAL	NA		Exact identifier — unii+route 120 equally ranked IID candidates
cetyl alcohol	CETYL ALCOHOL	936JST6JCN	AEROSOL, FOAM / TOPICAL		82 mg	Exact identifier — unii+route 120 equally ranked IID candidates
sodium benzoate	SODIUM BENZOATE	OJ245FE5EU	SYSTEM / TOPICAL		2 mg	Exact identifier — unii+route 75 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	SYSTEM / TOPICAL	3.1 mg		Exact identifier — unii+route 165 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	GEL / TOPICAL	0.05 %w/w		Exact identifier — unii+route 120 equally ranked IID candidates
cetyl alcohol	CETYL ALCOHOL	936JST6JCN	EMULSION / TOPICAL	NA		Exact identifier — unii+route 120 equally ranked IID candidates
sodium benzoate	SODIUM BENZOATE	OJ245FE5EU	GEL / TOPICAL		5 mg	Exact identifier — unii+route 75 equally ranked IID candidates
cetyl alcohol	CETYL ALCOHOL	936JST6JCN	AEROSOL, FOAM / TOPICAL		82 mg	Exact identifier — unii+route 120 equally ranked IID candidates
sodium benzoate	SODIUM BENZOATE	OJ245FE5EU	SOLUTION / TOPICAL	0.1 %w/v		Exact identifier — unii+route 75 equally ranked IID candidates
benzyl alcohol	BENZYL ALCOHOL	LKG8494WBH	OINTMENT / TOPICAL	2.2 %w/w		Exact identifier — unii+route 105 equally ranked IID candidates
benzyl alcohol	BENZYL ALCOHOL	LKG8494WBH	SUSPENSION / TOPICAL	1 %w/w		Exact identifier — unii+route 105 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	GEL / TOPICAL	0.18 %w/w		Exact identifier — unii+route 165 equally ranked IID candidates
Coco Monoethanolamide	COCO MONOETHANOLAMIDE	C80684146D	SHAMPOO / TOPICAL	4 %w/w		Exact identifier — unii+route 15 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	CREAM / TOPICAL	0.4 %w/w		Exact identifier — unii+route 165 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	SUSPENSION / TOPICAL	0.32 %w/v		Exact identifier — unii+route 165 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	SPRAY / TOPICAL		7 mg	Exact identifier — unii+route 120 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	SPRAY / TOPICAL		7 mg	Exact identifier — unii+route 120 equally ranked IID candidates
cetyl alcohol	CETYL ALCOHOL	936JST6JCN	SUSPENSION / TOPICAL	2.01 %w/w		Exact identifier — unii+route 120 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	SOAP / TOPICAL	1.26 %w/w		Exact identifier — unii+route 165 equally ranked IID candidates
sodium laureth-3 sulfate	SODIUM LAURETH-3 SULFATE	BPV390UAP0	SPRAY / TOPICAL	0.1 %w/w		Exact identifier — unii+route 45 equally ranked IID candidates
sodium benzoate	SODIUM BENZOATE	OJ245FE5EU	GEL / TOPICAL		5 mg	Exact identifier — unii+route 75 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	SPONGE / TOPICAL	5 %w/w		Exact identifier — unii+route 120 equally ranked IID candidates

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Head and Shoulders Smooth and Silky 2in1	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	6d1de62a-b1ab-4ae1-8b8d-e9f0b85beb59	2026-02-18	Warnings	Exact identifier ndc (package): 37000-095-83 ndc (package): 37000-095-93 ndc (package): 37000-095-25 ndc (package): 37000-095-12 ndc (package): 37000-095-37 ndc (package): 37000-095-65 ndc (package): 37000-095-38 ndc (package): 37000-095-61 ndc (package): 37000-095-95 ndc (package): 37000-095-20 ndc (package): 37000-095-70 ndc (package): 37000-095-40 ndc (package): 37000-095-01 ndc (package): 37000-095-13 ndc (product): 37000-095 ndc11 (package): 37000009520 ndc11 (package): 37000009501 ndc11 (package): 37000009561 ndc11 (package): 37000009525 ndc11 (package): 37000009593 ndc11 (package): 37000009538 ndc11 (package): 37000009570 ndc11 (package): 37000009512 ndc11 (package): 37000009583 ndc11 (package): 37000009565 ndc11 (package): 37000009537 ndc11 (package): 37000009540 ndc11 (package): 37000009513 ndc11 (package): 37000009595 spl id: 4b2042bd-401b-772c-e063-6294a90a8f40 spl set id: 6d1de62a-b1ab-4ae1-8b8d-e9f0b85beb59

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.