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Principal Secret

Manufacturer
Guthy-Renker LLC
Effective date
2026-05-29
Label type
HUMAN OTC DRUG LABEL
Version
1
Source
monthly-update
Hydrated at
2026-07-17 21:37:02

Label at a glance#

ProductPrincipal Secret Blemish Buster Clear
Active ingredientSalicylic Acid
Label structure11 sections

Indications and uses

For the management of acne

Dosage and administration

cleanse thoroughly before applying this product. cover the entire affected with a thin layer one to three times daily. because excessive drying of the skin may occur, start with one application daily, then gradually increase to two three times daily if needed or as directed by a doctor. if bothersome dryness or peeling occurs, reduce application to once a day or every other day. Sensitivity Test for a New User: Ap...

Storage and handling

Protect this product from excessive heat and direct sun.

Label contents#

Full prescribing information#

SPL UNCLASSIFIED SECTION

Drug Fact Label

Active ingredient

OTC - ACTIVE INGREDIENT SECTION

Salicylic 2%

Purpose

OTC - PURPOSE SECTION

Acne Treatment

Uses

INDICATIONS & USAGE SECTION

For the management of acne

Warnings

WARNINGS SECTION

For external use only.

OTC - WHEN USING SECTION

  • skin irritation and dryness are more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
  • avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water.

Stop use and ask a doctor if

OTC - STOP USE SECTION

  • irritation becomes severe.

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

Keep out of reach of children

  • If product is swallowed, get medical help or contact a Poison Control Center right away.

Directions

DOSAGE & ADMINISTRATION SECTION

  • cleanse thoroughly before applying this product.
  • cover the entire affected with a thin layer one to three times daily.
  • because excessive drying of the skin may occur, start with one application daily, then gradually increase to two three times daily if needed or as directed by a doctor.
  • if bothersome dryness or peeling occurs, reduce application to once a day or every other day.
  • Sensitivity Test for a New User:
    Apply product sparingly to one or two small, affected areas during the first 3 days. If no discomfort occurs, follow the directions stated above.

Inactive ingredients

INACTIVE INGREDIENT SECTION

Water, Alcohol, Glycerin, Hydroxyethylcellulose, PEG-8/SMDI Copolymer, Avena Sativa (Oat) Kernel Extract, Corallina Officinalis Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Butylene Glycol, t-Butyl Alcohol, Ethylhexylglycerin, Denatonium Benzoate, PPG-5-Ceteth-20, Sodium Hydroxide, Disodium EDTA, Phenoxyethanol

Other information

STORAGE AND HANDLING SECTION

  • Protect this product from excessive heat and direct sun.

Questions or comments?

OTC - QUESTIONS SECTION

Within US 1-800-510-4961

SPL UNCLASSIFIED SECTION

Dist. by: Guthy-Renker® LLC
El Segundo, CA 90245

PRINCIPAL DISPLAY PANEL - 15 ml Bottle Label

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

PRINCIPAL
SECRET®

Blemish
Buster®
Clear

Salicylic Acid
Acne Treatment

15 ml / 0.51 FL. Oz.

PRINCIPAL DISPLAY PANEL - 15 ml Bottle Label
PRINCIPAL DISPLAY PANEL - 15 ml Bottle Label

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 18 matching rows.

NDC Codes#

Product NDC, Package NDC table
Product NDCPackage NDC
70605-02170605-021-05

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 17 matching rows.

Name, UNII, Kind table
NameUNIIKind
Salicylic AcidO414PZ4LPZACTIB
Water059QF0KO0RIACT
GlycerinPDC6A3C0OXIACT
Alcohol3K9958V90MIACT
HYDROXYETHYL CELLULOSE, UNSPECIFIEDT4V6TWG28DIACT
PEG-8/SMDI CopolymerCCX72L6NY6IACT
ROSEMARYIJ67X351P9IACT
OATZ6J799EAJKIACT
CORALLINA OFFICINALIS4004498D06IACT
Butylene Glycol3XUS85K0RAIACT
TERT-BUTYL ALCOHOLMD83SFE959IACT
Ethylhexylglycerin147D247K3PIACT
Denatonium Benzoate4YK5Z54AT2IACT
PPG-5-Ceteth-204AAN25P8P4IACT
EDETATE DISODIUM7FLD91C86KIACT
Sodium Hydroxide55X04QC32IIACT
PhenoxyethanolHIE492ZZ3TIACT

Source Document#

Source XML

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Principal Secret Blemish Buster ClearSALICYLIC ACIDGuthy-Renker LLC75387738-eca2-4184-833b-95005eb276662026-05-29WarningsExact identifier
ndc (package): 70605-021-05
ndc (product): 70605-021
ndc11 (package): 70605002105
spl id: ae7ffcd8-1507-4b62-ae01-7b05195f299c
spl set id: 75387738-eca2-4184-833b-95005eb27666

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.