Indications and uses
For the temporary relief of joint pain and muscle pain associated with: Arthritis Backache Discomfort Cramps Neckache Soreness Sprains Strains
Neptune Ice
- Manufacturer
- Neptune Products L.L.C.
- Effective date
- 2023-12-14
- Label type
- HUMAN OTC DRUG LABEL
- Version
- 10
- Source
- legacy-cache
- Hydrated at
- 2026-08-01 21:18:19
Label at a glance#
ProductNeptune Ice
Active ingredientCAMPHOR (NATURAL), DIMETHICONE, LIDOCAINE, MENTHOL
Label structure15 sections
Dosage and administration
Ad ults and Children 12 years of Age and Older: Clean and dry the affected area Apply product directly to your skin, up to 4 times daily
Contacts and useful links#
Label contents#
Full prescribing information#
SPL UNCLASSIFIED SECTION
Methemoglobinemia
Cases of methemoglobinemia have been reported in association with local anesthetic use. Although all patients are at risk for methemoglobinemia, patients with glucose-6-phosphate dehydrogenase deficiency, congenital or idiopathic methemoglobinemia, cardiac or pulmonary compromise, infants under 6 months of age, and concurrent exposure to oxidizing agents or their metabolites are more susceptible to developing clinical manifestations of the condition. If local anesthetics must be used in these patients, close monitoring for symptoms and signs of methemoglobinemia is recommended.
Signs and symptoms of methemoglobinemia may occur immediately or may be delayed some hours after exposure and are characterized by a cyanotic skin discoloration and abnormal coloration of the blood. Methemoglobin levels may continue to rise; therefore, immediate treatment is required to avert more serious central nervous system and cardiovascular adverse effects, including seizures, coma, arrhythmias, and death. Discontinue lidocaine-containing products and any other oxidizing agents. Depending on the severity of the symptoms, patients may respond to supportive care, i.e., oxygen therapy, hydration. More severe symptoms may require treatment with methylene blue, exchange transfusion, or hyperbaric oxygen
Active Ingredient
Lidocaine 4%
Purpose
Topical Anesthetic
Active Ingredient
Menthol 1%
Purpose
Topical Analgesic
Active Ingredient
Camphor 3%
Purpose
Topical Analgesic
Active Ingredient
Dimethicone 3%
Purpose
Skin Conditioner
Uses:
For the temporary relief of joint pain and muscle pain associated with:
- Arthritis
- Backache
- Discomfort
- Cramps
- Neckache
- Soreness
- Sprains
- Strains
Warnings
For External Use Only
Flammable
Keep away from excessive heat or open flame
Do Not Use
- On damaged or irritated skin
- With a bandage or heating pad
- If you are allergic to any ingredients in this product
- Other than as directed
When Using This Product
Avoid contact with the eyes
Stop Use and Ask a Doctor If
- Condition worsens
- Excessive skin irritation develops
- Symptoms persist for more than 7 days, or symptoms clear up and occur again within 3 days
If You Are Pregnant or Breast Feeding
Ask a health professional before use
Keep Out of Reach of Children
If ingested, seek medical help or contact a Poison Control Center immediately
Directions
Adults and Children 12 years of Age and Older:
- Clean and dry the affected area
- Apply product directly to your skin, up to 4 times daily
Other Information
- Store in a cool, dry place with lid tightly closed
Inactive Ingredients
Aloe Barbadensis Leaf Juice, Arnica Montana Flower, Boswellia Serrata Extract, Carbomer, Ethylhexylglycerin, FD&C Blue #1, Methylsulfonylmethane, Phenoxyethanol, Polysorbate 20, SD-Alcohol 40B, Sorbitol, Triethanolamine, Water.
Questions or Comments?
(877) 985-8377
Principal Display Panel
DailyMed Billing Units#
| Package NDC | Billing unit | Product NDC | DailyMed indexing SPL | SPL version | Effective |
|---|---|---|---|---|---|
| 72594-1846-8 | GM - Gram | 72594-1846 | 7ee52ed6-61c3-409d-9887-d0afcf176fcc | 1 | 2019-08-06 |
Products#
Every source-derived product name is available through these pages.
- Neptune Ice
- Lidocaine, Menthol, Camphor, and Dimethicone Gel
- ALOE VERA LEAF
- POLYSORBATE 20
- FD&C BLUE NO. 1
- ETHYLHEXYLGLYCERIN
- ARNICA MONTANA FLOWER
- PHENOXYETHANOL
- CARBOXYPOLYMETHYLENE
- BOSWELLIA SERRATA RESIN OIL
- WATER
- DIMETHYL SULFONE
- ALCOHOL
- TROLAMINE
- SORBITOL
- CAMPHOR (NATURAL)
- DIMETHICONE
- LIDOCAINE
- MENTHOL
NDC Codes#
| Product NDC | Package NDC |
|---|---|
| 72594-1846 | 72594-1846-8 |
Ingredients#
Every source-derived ingredient row is available through these pages.
| Name | UNII | Kind |
|---|---|---|
| ALOE VERA LEAF | ZY81Z83H0X | IACT |
| POLYSORBATE 20 | 7T1F30V5YH | IACT |
| FD&C BLUE NO. 1 | H3R47K3TBD | IACT |
| ETHYLHEXYLGLYCERIN | 147D247K3P | IACT |
| ARNICA MONTANA FLOWER | OZ0E5Y15PZ | IACT |
| PHENOXYETHANOL | HIE492ZZ3T | IACT |
| CARBOXYPOLYMETHYLENE | 0A5MM307FC | IACT |
| BOSWELLIA SERRATA RESIN OIL | 5T1XCE6K8K | IACT |
| WATER | 059QF0KO0R | IACT |
| DIMETHYL SULFONE | 9H4PO4Z4FT | IACT |
| ALCOHOL | 3K9958V90M | IACT |
| TROLAMINE | 9O3K93S3TK | IACT |
| SORBITOL | 506T60A25R | IACT |
| CAMPHOR (NATURAL) | N20HL7Q941 | ACTIB |
| DIMETHICONE | 92RU3N3Y1O | ACTIB |
| LIDOCAINE | 98PI200987 | ACTIB |
| MENTHOL | L7T10EIP3A | ACTIB |
Source Document#
openFDA label cross-check#
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| 0c7d382a-b977-6159-e063-6294a90a886f | 7759b4c9-ff17-2c69-e053-2a91aa0a2559 | 2023-12-14 | Warnings | 0c7d382a-b977-6159-e063-6294a90a886f 7759b4c9-ff17-2c69-e053-2a91aa0a2559 |
Reported adverse events (FAERS/openFDA)#
Adverse event summaries are temporarily unavailable. Other product information remains available.