FDA.reportPublic FDA data

Head and Shoulders Men Advanced Series Refreshing 2in1 Menthol

Manufacturer
The Procter & Gamble Manufacturing Company
Effective date
2025-12-16
Label type
HUMAN OTC DRUG LABEL
Version
6
Source
full-release
Hydrated at
2026-06-01 01:25:43

Label at a glance#

ProductHead and Shoulders Men Advanced Series Refreshing 2in1 Menthol
Active ingredientPYRITHIONE ZINC
Label structure10 sections

Indications and uses

helps prevent recurrence of flaking and itching associated with dandruff.

Dosage and administration

for best results use at least twice a week or as directed by a doctor. for maximum dandruff control, use every time you shampoo. shake before use. wet hair, massage onto scalp, rinse, repeat if desired.

Label contents#

Full prescribing information#

SPL UNCLASSIFIED SECTION

Drug Facts

Active ingredient

OTC - ACTIVE INGREDIENT SECTION

Pyrithione zinc 1%

Purpose

OTC - PURPOSE SECTION

Anti-dandruff

Uses

INDICATIONS & USAGE SECTION

helps prevent recurrence of flaking and itching associated with dandruff.

Warnings

WARNINGS SECTION

SPL UNCLASSIFIED SECTION

For external use only.

OTC - WHEN USING SECTION

When using this product

  • avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water.

OTC - STOP USE SECTION

Stop use and ask a doctor if

  • condition worsens or does not improve after regular use of this product as directed.

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

Keep this and all drugs out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Directions

DOSAGE & ADMINISTRATION SECTION

  • for best results use at least twice a week or as directed by a doctor.
  • for maximum dandruff control, use every time you shampoo.
  • shake before use.
  • wet hair, massage onto scalp, rinse, repeat if desired.

Inactive ingredients

INACTIVE INGREDIENT SECTION

Water, sodium lauryl sulfate, sodium laureth sulfate, glycol distearate, sodium chloride, zinc carbonate, dimethicone, cocamidopropyl
betaine, sodium xylenesulfonate, fragrance, menthol, sodium benzoate, guar hydroxypropyltrimonium chloride, magnesium carbonate hydroxide,mentha piperita (peppermint) flower/leaf/stemoil, mentha arvensis leaf/stem oil, blue 1, red 33

Questions (or comments)?

OTC - QUESTIONS SECTION

1-800-723-9569

SPL UNCLASSIFIED SECTION

Dist. by PROCTER & GAMBLE,
CINCINNATI, OH 45202

PRINCIPAL DISPLAY PANEL - 370 mL Bottle Label

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

head &

shoulders

PYRITHIONE ZINC DANDRUFF

SHAMPOO + CONDITIONER

2in1

MEN

REFRESHING MENTHOL

Intensely cools &

energizes scalp

FLAKE FREE

UP TO 100%

GUARANTEED

12.5 FL OZ (370 mL)

HSHS

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYSPL version
1043244head & shoulders 1 % Medicated ShampooPSN6
209884zinc pyrithione 1 % Medicated ShampooPSN6
1043244zinc pyrithione 10 MG/ML Medicated Shampoo [Head & Shoulders]SBD6
209884zinc pyrithione 10 MG/ML Medicated ShampooSCD6
1043244Head & Shoulders 1 % Medicated ShampooSY6
1043244Head & Shoulders 10 MG/ML Medicated ShampooSY6
209884zinc pyrithione 1 % Medicated ConditionerSY6
209884zinc pyrithione 1 % Medicated ShampooSY6

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDCEffectiveActionDocumentIndexing SPLRelated label
69423-312-382023-02-27C16284748780-19d75b9d0-c448-f424-e053-dadaa90a57ceHead and Shoulders ® Men Advanced Series Refreshing 2in1 Menthol Shampoo
69423-312-652023-02-27C16284748780-19d75b9d0-c448-f424-e053-dadaa90a57ceHead and Shoulders ® Men Advanced Series Refreshing 2in1 Menthol Shampoo
69423-312-382022-01-28C16284748780-19d75b9d0-c448-f424-e053-dadaa90a57ceHead and Shoulders ® Men Advanced Series Refreshing 2in1 Menthol Shampoo
69423-312-652022-01-28C16284748780-19d75b9d0-c448-f424-e053-dadaa90a57ceHead and Shoulders ® Men Advanced Series Refreshing 2in1 Menthol Shampoo
69423-312-382020-02-06C16284748780-19d75b9d0-c448-f424-e053-dadaa90a57ceHead and Shoulders ® Men Advanced Series Refreshing 2in1 Menthol Shampoo
69423-312-652020-02-06C16284748780-19d75b9d0-c448-f424-e053-dadaa90a57ceHead and Shoulders ® Men Advanced Series Refreshing 2in1 Menthol Shampoo
69423-312-382020-01-31C16284748780-19d75b9d0-c448-f424-e053-dadaa90a57ceHead and Shoulders ® Men Advanced Series Refreshing 2in1 Menthol Shampoo
69423-312-652020-01-31C16284748780-19d75b9d0-c448-f424-e053-dadaa90a57ceHead and Shoulders ® Men Advanced Series Refreshing 2in1 Menthol Shampoo

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
69423-312-37Head and Shoulders Men Advanced Series Refreshing 2in1 Menthol370 mL in 1 BOTTLE, PLASTICLOTION/SHAMPOO3706
69423-312-38Head and Shoulders Men Advanced Series Refreshing 2in1 Menthol380 mL in 1 BOTTLE, PLASTICLOTION/SHAMPOO3806
69423-312-65Head and Shoulders Men Advanced Series Refreshing 2in1 Menthol650 mL in 1 BOTTLE, PLASTICLOTION/SHAMPOO6506

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 21 matching rows.

NDC Codes#

Product NDC, Package NDC table
Product NDCPackage NDC
69423-31269423-312-38, 69423-312-65, 69423-312-37

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 19 matching rows.

Name, UNII, Kind table
NameUNIIKind
FD&C BLUE NO. 1H3R47K3TBDIACT
D&C RED NO. 339DBA0SBB0LIACT
PYRITHIONE ZINCR953O2RHZ5ACTIB
MENTHOLL7T10EIP3AIACT
GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE (1.7 SUBSTITUENTS PER SACCHARIDE)B16G315W7AIACT
MENTHA ARVENSIS LEAF OIL1AEY1M553NIACT
PEPPERMINT OILAV092KU4JHIACT
WATER059QF0KO0RIACT
SODIUM LAURETH-3 SULFATEBPV390UAP0IACT
GLYCOL DISTEARATE13W7MDN21WIACT
ZINC CARBONATEEQR32Y7H0MIACT
SODIUM CHLORIDE451W47IQ8XIACT
SODIUM XYLENESULFONATEG4LZF950URIACT
COCAMIDOPROPYL BETAINE5OCF3O11KXIACT
DIMETHICONE92RU3N3Y1OIACT
SODIUM BENZOATEOJ245FE5EUIACT
MAGNESIUM CARBONATE HYDROXIDEYQO029V1L4IACT
SODIUM LAURYL SULFATE368GB5141JIACT
MENTHA PIPERITA LEAFA389O33LX6IACT

Source Document#

Source XML

openFDA label cross-check#

Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report. Every label matching the complete exact-identifier union is deduplicated and paginated below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Head and Shoulders Men Advanced Series Refreshing 2in1 MentholPYRITHIONE ZINCThe Procter & Gamble Manufacturing Company7c5db483-e0e7-4c8a-e053-2a91aa0aeda32025-12-16WarningsExact identifier
ndc (package): 69423-312-65
ndc (package): 69423-312-37
ndc (package): 69423-312-38
ndc (product): 69423-312
ndc11 (package): 69423031237
ndc11 (package): 69423031238
ndc11 (package): 69423031265
spl id: 46149258-59f2-ae70-e063-6294a90a684e
spl set id: 7c5db483-e0e7-4c8a-e053-2a91aa0aeda3