CVS Itch Relief Continuous Spray

Manufacturer: CVS Pharmacy
Effective date: 2026-04-01
Label type: HUMAN OTC DRUG LABEL
Version: 8
Source: full-release
Hydrated at: 2026-06-01 01:52:20

Label at a glance#

ProductItch Relief

Active ingredientDIPHENHYDRAMINE HYDROCHLORIDE, ZINC ACETATE

Label structure9 sections

Indications and uses

for the temporary relief of pain and itching associated with: minor burns sunburn minor cuts scrapes insect bites minor skin irritations rashes due to poison ivy, poison oak and poison sumac dries the oozing and weeping of poison ivy, poison oak and poison sumac

Dosage and administration

do not use more often than directed adults and children 2 years of age and older: apply to affected area not more than 3 to 4 times daily children under 2 years of age: ask a doctor

Contacts and useful links#

PhoneLabel contact1-866-964-0939

Label contents#

Full prescribing information#

Active ingredients

OTC - ACTIVE INGREDIENT SECTION

Diphenhydramine HCl 2.0%,
Zinc Acetate 0.1%

Purpose

OTC - PURPOSE SECTION

External analgesic
Skin protectant

Uses

INDICATIONS & USAGE SECTION

for the temporary relief of pain and itching associated with:

minor burns
sunburn
minor cuts
scrapes
insect bites
minor skin irritations
rashes due to poison ivy, poison oak and poison sumac
dries the oozing and weeping of poison ivy, poison oak and poison sumac

Warnings

WARNINGS SECTION

For external use only.

Flammable:

SAFE HANDLING WARNING SECTION

Keep away from fire or flame. Do not puncture or incinerate. Contents under pressure. Do not store at temperatures above 120°F. Intentional misuse by delibrately concenrating and inhaling contents can be harmful or fatal.

Do not use

OTC - DO NOT USE SECTION

on large areas of the body
with any other product containing diphenhydramine, even one taken by mouth

Ask a doctor before use

WARNINGS SECTION

on chicken pox
on measles

When using this product

OTC - WHEN USING SECTION

avoid contact with eyes

Stop use and ask doctor if

OTC - STOP USE SECTION

conditions worsens
symptoms last more than 7 days or clear up and occur again within a few days

Keep out of reach of children.

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

If swallowed, get medical help or contact a Poison Control Center right away.

Directions

DOSAGE & ADMINISTRATION SECTION

do not use more often than directed
adults and children 2 years of age and older: apply to affected area not more than 3 to 4 times daily
children under 2 years of age: ask a doctor

Other information

OTHER SAFETY INFORMATION

store between 20° to 25°C (68° to 77°F)

Inactive ingredients

INACTIVE INGREDIENT SECTION

aloe barbadensis leaf juice, glycerin, purified water, SD alcohol 40-B, tromethamine

Questions?

OTC - QUESTIONS SECTION

1-866-964-0939

Principal Display Panel

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

CVS

Extra Strength

ITCH RELIEF
SPRAY

Diphenhydramine HCl 2%
Topical Analgesic

Zinc Acetate 0.1%
Skin Protectant

Compare to Benadryl® Extra Strength
Itch Cooling Spray active ingredients*

Relieves Itching From: Insect
bites, Poison ivy, oak & sumac

Soothes Sunburn, Minor
Burns & Cuts

Sprays at
Any Angle

For Topical
Use Only

NET WT 2.7 OZ (76g)

carton

RxCUI, Display, Full name table
RxCUI	Display	Full name	Type	Form / route
1053138	diphenhydrAMINE/Zinc acetate (Topical)	diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Spray	SCD Active

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	SPL version
1053138	diphenhydrAMINE HCl 2 % / zinc acetate 0.1 % Topical Spray	PSN	8
1053138	diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Spray	SCD	8
1053138	diphenhydramine hydrochloride 2 % / zinc acetate 0.1 % Topical Spray	SY	8

DailyMed Pharmacologic Classes#

Class, Version, Type table
Class	Version	Type	Effective
DIPHENHYDRAMINE Pharmacologic Class Indexing	3	Indexing - Pharmacologic Class	20180813
ZINC CATION Pharmacologic Class Indexing	2	Indexing - Pharmacologic Class	20180813

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
f47a510b-6679-4664-b2d6-47b5c4afe7cc	Product name	4	20260217
77dc03a4-fbfc-e6a3-fe95-285bbae40d75	Product name	2	20250814
030ce964-9b2d-45aa-b5d3-f78ce03ef61c	Product name	2	20250515
0e2e0f88-b076-afe1-4bdd-32bca4375bec	Product name	3	20250127
0306390c-dd77-4363-afe0-63c58088b2a1	Product name	1	20220120
503ea967-4b9c-48cf-9e87-c7975295849d	Product name	2	20220120
190f2a5b-bbc8-65c7-fcb0-97891307b917	Product name	1	20140508
3e48c9c4-918d-5d23-2f0b-d2398b06be54	Product name	1	20140508
865c72dd-0d94-daac-f728-ddd4ded2a79e	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
69842-235-27	Itch Relief	76 g in 1 CANISTER	AEROSOL, SPRAY	76		8

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
69842-235-27	GM - Gram	69842-235	e0d5b9f3-743e-4197-a894-215ee5ece1f2	1	2021-05-05

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 11 matching rows.

Itch Relief
Diphenhydramine HCl and Zinc Acetate
DIPHENHYDRAMINE HYDROCHLORIDE
DIPHENHYDRAMINE
ZINC ACETATE
ZINC CATION
GLYCERIN
ALCOHOL
TROMETHAMINE
ALOE BARBADENSIS LEAF
WATER

NDC Codes#

Product NDC, Package NDC table
Product NDC	Package NDC
69842-235	69842-235-27

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 7 matching rows.

Name, UNII, Kind table
Name	UNII	Kind
DIPHENHYDRAMINE HYDROCHLORIDE	TC2D6JAD40	ACTIB
ZINC ACETATE	FM5526K07A	ACTIB
GLYCERIN	PDC6A3C0OX	IACT
ALCOHOL	3K9958V90M	IACT
TROMETHAMINE	023C2WHX2V	IACT
ALOE BARBADENSIS LEAF	ZY81Z83H0X	IACT
WATER	059QF0KO0R	IACT

Source Document#

Source XML · Source PDF

Older Hydrated Versions#

Version, Effective date, Source table
Version	Effective date	Source	Hydrated
7	2025-10-29	monthly-update	2026-06-03 17:39:19
6	2024-11-15	full-release	2026-06-01 00:37:27

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Itch Relief	DIPHENHYDRAMINE HCL AND ZINC ACETATE	CVS Pharmacy	7e921988-ec66-38dc-e053-2a91aa0a7346	2026-04-01	Warnings	Exact identifier ndc (package): 69842-235-27 ndc (product): 69842-235 ndc11 (package): 69842023527 spl id: 4e68977a-63bb-1af9-e063-6394a90a737e spl set id: 7e921988-ec66-38dc-e053-2a91aa0a7346

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.