Indications and uses
for the temporary relief of these symptoms associated with menstrual periods: headache bloating cramps backache muscular aches irritability water-weight gain
CVS 44-679 RESERVED 51316-679
- Manufacturer
- CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED | LNK International, Inc.
- Effective date
- 2026-05-11
- Label type
- HUMAN OTC DRUG LABEL
- Version
- 4
- Source
- monthly-update
- Hydrated at
- 2026-07-17 21:35:37
Label at a glance#
ProductMulti-Symptom PMS Relief
Active ingredientACETAMINOPHEN, PAMABROM, PYRILAMINE MALEATE
Label structure9 sections
Dosage and administration
do not take more than directed adults and children 12 years and over: take 2 caplets with water every 6 hours as needed do not exceed 6 caplets in a 24 hour period or as directed by a doctor children under 12 years: ask a doctor
Storage and handling
store at 25ºC (77ºF); excursions permitted between 15º-30ºC (59º-86ºF) see end flap for expiration date and lot number
Contacts and useful links#
Label contents#
Full prescribing information#
Active ingredients (in each caplet)
Acetaminophen 500 mg
Pamabrom 25 mg
Pyrilamine maleate 15 mg
Purpose
Pain reliever
Diuretic
Antihistamine
Uses
for the temporary relief of these symptoms associated with menstrual periods:
- headache
- bloating
- cramps
- backache
- muscular aches
- irritability
- water-weight gain
Warnings
Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take
- more than 4,000 mg of acetaminophen in 24 hours
- with other drugs containing acetaminophen
- 3 or more alcoholic drinks every day while using this product
Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include:
- skin reddening
- blisters
- rash
If a skin reaction occurs, stop use and seek medical help right away.
Do not use
- with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
- if you have ever had an allergic reaction to this product or any of its ingredients
Ask a doctor before use if you have
- difficulty in urination due to enlargement of the prostate gland
- liver disease
- a breathing problem such as emphysema or chronic bronchitis
- glaucoma
Ask a doctor or pharmacist before use if you are
- taking the blood thinning drug warfarin
- taking sedatives or tranquilizers
When using this product
- drowsiness may occur
- avoid alcoholic beverages
- excitability may occur, especially in children
- alcohol, sedatives and tranquilizers may increase drowsiness
- use caution when driving a motor vehicle or operating machinery
Stop use and ask a doctor if
- pain gets worse or lasts more than 10 days
- fever gets worse or lasts more than 3 days
- new symptoms occur
- redness or swelling is present
These could be signs of a serious condition.
If pregnant or breast-feeding,
ask a health professional before use.
Keep out of reach of children.
In case of accidental overdose, get medical help or contact a Poison Control Center right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Directions
- do not take more than directed
- adults and children 12 years and over:
- take 2 caplets with water every 6 hours as needed
- do not exceed 6 caplets in a 24 hour period or as directed by a doctor
- children under 12 years: ask a doctor
Other information
- store at 25ºC (77ºF); excursions permitted between 15º-30ºC (59º-86ºF)
- see end flap for expiration date and lot number
Inactive ingredients
corn starch, croscarmellose sodium, crospovidone, FD&C blue #2 aluminum lake, FD&C red #40 aluminum lake, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone, shellac wax, silicon dioxide, stearic acid, talc, titanium dioxide
Questions or comments?
1-800-426-9391
Principal Display Panel
CVS™
NDC 51316-679-27
Maximum Strength†
MULTI-SYMPTOM PMS RELIEF
Acetaminophen, 500 mg, Pain Reliever
Pamabrom, 25 mg, Diuretic | Pyrilamine Maleate, 15 mg, Antihistamine
Compare to Maximum Strength Pamprin® Multi-Symptom active ingredients*
Relieves: Cramps, Bloating,
Headache, Backache,
Water-weight gain
actual
size
32 COATED
CAPLETS
†Under OTC monograph.
Products#
Every source-derived product name is available through these pages.
- Multi-Symptom PMS Relief
- Acetaminophen, Pamabrom, Pyrilamine maleate
- ACETAMINOPHEN
- PAMABROM
- BROMOTHEOPHYLLINE
- PYRILAMINE MALEATE
- PYRILAMINE
- STARCH, CORN
- CROSCARMELLOSE SODIUM
- CROSPOVIDONE, UNSPECIFIED
- FD&C BLUE NO. 2 ALUMINUM LAKE
- FD&C RED NO. 40 ALUMINUM LAKE
- MAGNESIUM STEARATE
- MICROCRYSTALLINE CELLULOSE
- POLYETHYLENE GLYCOL, UNSPECIFIED
- POLYVINYL ALCOHOL, UNSPECIFIED
- POVIDONE, UNSPECIFIED
- SHELLAC
- SILICON DIOXIDE
- STEARIC ACID
- TALC
- TITANIUM DIOXIDE
NDC Codes#
| Product NDC | Package NDC |
|---|---|
| 51316-679 | 51316-679-27 |
Ingredients#
Every source-derived ingredient row is available through these pages.
Source Document#
Older Hydrated Versions#
| Version | Effective date | Source | Hydrated |
|---|---|---|---|
| 2 | 2026-05-11 | daily-update | 2026-06-06 05:10:15 |
openFDA label cross-check#
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| Multi-Symptom PMS Relief | ACETAMINOPHEN, PAMABROM, PYRILAMINE MALEATE | CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED | 81ef39e2-b91e-4d34-b594-4ba557cc319b | 2026-05-11 | Warnings | 51316-679-27 51316-679 51316067927 e94add3f-a391-42e9-b71d-6db942292f7f 81ef39e2-b91e-4d34-b594-4ba557cc319b |
Reported adverse events (FAERS/openFDA)#
Adverse event summaries are temporarily unavailable. Other product information remains available.