Head and Shoulders Supreme Detox and Hydrate Conditioner

Manufacturer: The Procter & Gamble Manufacturing Company
Effective date: 2025-12-18
Label type: HUMAN OTC DRUG LABEL
Version: 8
Source: full-release
Hydrated at: 2026-06-01 01:26:53

Label at a glance#

ProductHead and Shoulders Supreme Detox and Hydrate Conditioner

Active ingredientPYRITHIONE ZINC

Label structure10 sections

Indications and uses

helps prevent recurrence of flaking and itching associated with dandruff.

Dosage and administration

for best results use at least twice a week or as directed by a doctor. apply to wet hair after shampooing by gently massaging into hair and scalp, rinse well.

Contacts and useful links#

PhoneLabel contact1-800-723-9569

Label contents#

Full prescribing information#

SPL UNCLASSIFIED SECTION

Drug Facts

Active ingredient

OTC - ACTIVE INGREDIENT SECTION

Pyrithione zinc 0.5%

Purpose

OTC - PURPOSE SECTION

Anti-dandruff

Uses

INDICATIONS & USAGE SECTION

helps prevent recurrence of flaking and itching associated with dandruff.

Warnings

WARNINGS SECTION

SPL UNCLASSIFIED SECTION

For external use only.

OTC - WHEN USING SECTION

When using this product

avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water.

OTC - STOP USE SECTION

Stop use and ask a doctor if

condition worsens or does not improve after regular use of this product as directed.

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

Keep this and all drugs out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Directions

DOSAGE & ADMINISTRATION SECTION

for best results use at least twice a week or as directed by a doctor.
apply to wet hair after shampooing by gently massaging into hair and scalp, rinse well.

Inactive ingredients

INACTIVE INGREDIENT SECTION

Water, stearyl alcohol, behentrimonium chloride, cetyl alcohol, argania spinosa kernel oil, zea mays (corn) silk extract, cocos nucifera (coconut) fruit extract, fragrance, phenoxyethanol, benzyl alcohol, methylchloroisothiazolinone, methylisothiazolinone

Questions (or comments)?

OTC - QUESTIONS SECTION

1-800-723-9569

SPL UNCLASSIFIED SECTION

Dist. by PROCTER & GAMBLE,
CINCINNATI, OH 45202

PRINCIPAL DISPLAY PANEL - 247 mL Tube Label

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

head &
shoulders _®
PYRITHION ZINC DANDRUFF

SCALP & HAIR CONDITIONER

SUPREME

DETOX &

HYDRATE

WITH ARGAN OIL & COCONUT WATER

FREE FROM

SULFATES

PARABENS

PHTHALATES

DYES

9.4 FL OZ
(278 mL)

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	SPL version
1044465	head & shoulders 0.5 % Medicated Shampoo	PSN	8
1043014	zinc pyrithione 0.5 % Medicated Conditioner	PSN	8
1044465	zinc pyrithione 5 MG/ML Medicated Shampoo [Head & Shoulders]	SBD	8
1043014	zinc pyrithione 5 MG/ML Medicated Shampoo	SCD	8
1044465	Head & Shoulders 0.5 % Conditioner	SY	8
1044465	Head & Shoulders 5 MG/ML Medicated Shampoo	SY	8
1043014	zinc pyrithione 0.5 % Medicated Shampoo	SY	8

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
69423-347-27	Head and Shoulders Supreme Detox and Hydrate Conditioner	278 mL in 1 TUBE	LOTION	278		8

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 13 matching rows.

Head and Shoulders Supreme Detox and Hydrate Conditioner
Pyrithione Zinc
BENZYL ALCOHOL
COCONUT OIL
METHYLCHLOROISOTHIAZOLINONE
METHYLISOTHIAZOLINONE
ARGAN OIL
CORN SILK
BEHENTRIMONIUM CHLORIDE
WATER
STEARYL ALCOHOL
CETYL ALCOHOL
PHENOXYETHANOL

NDC Codes#

Product NDC, Package NDC table
Product NDC	Package NDC
69423-347	69423-347-27

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 12 matching rows.

Name, UNII, Kind table
Name	UNII	Kind
BENZYL ALCOHOL	LKG8494WBH	IACT
COCONUT OIL	Q9L0O73W7L	IACT
METHYLCHLOROISOTHIAZOLINONE	DEL7T5QRPN	IACT
METHYLISOTHIAZOLINONE	229D0E1QFA	IACT
PYRITHIONE ZINC	R953O2RHZ5	ACTIB
ARGAN OIL	4V59G5UW9X	IACT
CORN SILK	7D3VB244UX	IACT
BEHENTRIMONIUM CHLORIDE	X7GNG3S47T	IACT
WATER	059QF0KO0R	IACT
STEARYL ALCOHOL	2KR89I4H1Y	IACT
CETYL ALCOHOL	936JST6JCN	IACT
PHENOXYETHANOL	HIE492ZZ3T	IACT

Source Document#

Source XML

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Head and Shoulders Supreme Detox and Hydrate Conditioner	PYRITHIONE ZINC	The Procter & Gamble Manufacturing Company	86ab72bc-4e9d-0075-e053-2a91aa0a1135	2025-12-18	Warnings	Exact identifier ndc (package): 69423-347-27 ndc (product): 69423-347 ndc11 (package): 69423034727 spl id: 4640c427-fbac-1ff7-e063-6394a90a4e63 spl set id: 86ab72bc-4e9d-0075-e053-2a91aa0a1135

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.