National Council for Prescription Drug Programs indexing - billing unit

Manufacturer: National Council for Prescription Drug Programs
Effective date: 2013-02-13
Label type: Indexing - Billing Unit
Version: 1
Source: full-release
Hydrated at: 2026-06-05 03:18:36

Label at a glance#

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
10019-120-39	ML - Milliliter	10019-120	98f059c6-92da-4bd0-8b8a-bdba162d9505	1	2013-02-13

NDC Codes#

Product NDC, Package NDC table
Product NDC	Package NDC
10019-120	10019-120-39

Source Document#

Source XML

Orange Book application contexts#

All distinct exact application/product contexts derived from this label’s complete NDC list are paginated below.

Orange Book application contexts page 1 of 1 · 1 matching rows.

Source provenance: Browse the complete Orange Book source catalog · source snapshot 43.

Orange Book products#

Current product rows page 1 of 1 · 5 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
N019386-003	BREVIBLOC	ESMOLOL HYDROCHLORIDE	10MG/ML	INJECTABLE / INJECTION			1988-08-15
N019386-004	BREVIBLOC IN PLASTIC CONTAINER	ESMOLOL HYDROCHLORIDE	1GM/100ML	INJECTABLE / INJECTION	AP	RLD, RS	2001-02-16
N019386-005	BREVIBLOC DOUBLE STRENGTH IN PLASTIC CONTAINER	ESMOLOL HYDROCHLORIDE	2GM/100ML	INJECTABLE / INJECTION	AP	RLD, RS	2003-01-27
N019386-006	BREVIBLOC	ESMOLOL HYDROCHLORIDE	10MG/ML	INJECTABLE / INJECTION	AP	RLD, RS	2003-02-25
N019386-007	BREVIBLOC	ESMOLOL HYDROCHLORIDE	20MG/ML	INJECTABLE / INJECTION			2003-05-28

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 3 matching rows.

Application-product, TE code table
Application-product	TE code
N019386-004	AP
N019386-005	AP
N019386-006	AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 6 · 215 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Product TE source text	RLD / RS	Approval date	Source SHA-256
2026-09-14 22:38:34	2026-08	N019386-003	BREVIBLOC	10MG/ML	INJECTABLE / INJECTION			1988-08-15	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N019386-004	BREVIBLOC IN PLASTIC CONTAINER	1GM/100ML	INJECTABLE / INJECTION	AP	RLD, RS	2001-02-16	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N019386-005	BREVIBLOC DOUBLE STRENGTH IN PLASTIC CONTAINER	2GM/100ML	INJECTABLE / INJECTION	AP	RLD, RS	2003-01-27	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N019386-006	BREVIBLOC	10MG/ML	INJECTABLE / INJECTION	AP	RLD, RS	2003-02-25	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N019386-007	BREVIBLOC	20MG/ML	INJECTABLE / INJECTION			2003-05-28	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	N019386-003	BREVIBLOC	10MG/ML	INJECTABLE / INJECTION			1988-08-15	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N019386-004	BREVIBLOC IN PLASTIC CONTAINER	1GM/100ML	INJECTABLE / INJECTION	AP	RLD, RS	2001-02-16	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N019386-005	BREVIBLOC DOUBLE STRENGTH IN PLASTIC CONTAINER	2GM/100ML	INJECTABLE / INJECTION	AP	RLD, RS	2003-01-27	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N019386-006	BREVIBLOC	10MG/ML	INJECTABLE / INJECTION	AP	RLD, RS	2003-02-25	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N019386-007	BREVIBLOC	20MG/ML	INJECTABLE / INJECTION			2003-05-28	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	N019386-003	BREVIBLOC	10MG/ML	INJECTABLE / INJECTION			1988-08-15	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N019386-004	BREVIBLOC IN PLASTIC CONTAINER	1GM/100ML	INJECTABLE / INJECTION	AP	RLD, RS	2001-02-16	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N019386-005	BREVIBLOC DOUBLE STRENGTH IN PLASTIC CONTAINER	2GM/100ML	INJECTABLE / INJECTION	AP	RLD, RS	2003-01-27	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N019386-006	BREVIBLOC	10MG/ML	INJECTABLE / INJECTION	AP	RLD, RS	2003-02-25	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N019386-007	BREVIBLOC	20MG/ML	INJECTABLE / INJECTION			2003-05-28	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N019386-003	BREVIBLOC	10MG/ML	INJECTABLE / INJECTION			1988-08-15	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N019386-004	BREVIBLOC IN PLASTIC CONTAINER	1GM/100ML	INJECTABLE / INJECTION	AP	RLD, RS	2001-02-16	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N019386-005	BREVIBLOC DOUBLE STRENGTH IN PLASTIC CONTAINER	2GM/100ML	INJECTABLE / INJECTION	AP	RLD, RS	2003-01-27	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N019386-006	BREVIBLOC	10MG/ML	INJECTABLE / INJECTION	AP	RLD, RS	2003-02-25	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N019386-007	BREVIBLOC	20MG/ML	INJECTABLE / INJECTION			2003-05-28	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N019386-003	BREVIBLOC	10MG/ML	INJECTABLE / INJECTION			1988-08-15	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N019386-004	BREVIBLOC IN PLASTIC CONTAINER	1GM/100ML	INJECTABLE / INJECTION	AP	RLD, RS	2001-02-16	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N019386-005	BREVIBLOC DOUBLE STRENGTH IN PLASTIC CONTAINER	2GM/100ML	INJECTABLE / INJECTION	AP	RLD, RS	2003-01-27	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N019386-006	BREVIBLOC	10MG/ML	INJECTABLE / INJECTION	AP	RLD, RS	2003-02-25	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N019386-007	BREVIBLOC	20MG/ML	INJECTABLE / INJECTION			2003-05-28	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N019386-003	BREVIBLOC	10MG/ML	INJECTABLE / INJECTION			1988-08-15	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N019386-004	BREVIBLOC IN PLASTIC CONTAINER	1GM/100ML	INJECTABLE / INJECTION	AP	RLD, RS	2001-02-16	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N019386-005	BREVIBLOC DOUBLE STRENGTH IN PLASTIC CONTAINER	2GM/100ML	INJECTABLE / INJECTION	AP	RLD, RS	2003-01-27	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N019386-006	BREVIBLOC	10MG/ML	INJECTABLE / INJECTION	AP	RLD, RS	2003-02-25	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N019386-007	BREVIBLOC	20MG/ML	INJECTABLE / INJECTION			2003-05-28	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N019386-003	BREVIBLOC	10MG/ML	INJECTABLE / INJECTION			1988-08-15	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N019386-004	BREVIBLOC IN PLASTIC CONTAINER	1GM/100ML	INJECTABLE / INJECTION	AP	RLD, RS	2001-02-16	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N019386-005	BREVIBLOC DOUBLE STRENGTH IN PLASTIC CONTAINER	2GM/100ML	INJECTABLE / INJECTION	AP	RLD, RS	2003-01-27	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N019386-006	BREVIBLOC	10MG/ML	INJECTABLE / INJECTION	AP	RLD, RS	2003-02-25	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N019386-007	BREVIBLOC	20MG/ML	INJECTABLE / INJECTION			2003-05-28	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N019386-003	BREVIBLOC	10MG/ML	INJECTABLE / INJECTION			1988-08-15	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N019386-004	BREVIBLOC IN PLASTIC CONTAINER	1GM/100ML	INJECTABLE / INJECTION	AP	RLD, RS	2001-02-16	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N019386-005	BREVIBLOC DOUBLE STRENGTH IN PLASTIC CONTAINER	2GM/100ML	INJECTABLE / INJECTION	AP	RLD, RS	2003-01-27	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N019386-006	BREVIBLOC	10MG/ML	INJECTABLE / INJECTION	AP	RLD, RS	2003-02-25	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N019386-007	BREVIBLOC	20MG/ML	INJECTABLE / INJECTION			2003-05-28	`03ed91905a0d…`

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 93 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	TE code	Order	Source SHA-256
2026-09-14 22:38:34	2026-08	N019386-004	AP	1	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N019386-005	AP	1	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	N019386-006	AP	1	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	N019386-004	AP	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N019386-005	AP	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	N019386-006	AP	1	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	N019386-004	AP	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N019386-005	AP	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N019386-006	AP	1	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N019386-004	AP	1	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N019386-005	AP	1	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N019386-006	AP	1	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N019386-004	AP	1	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N019386-005	AP	1	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N019386-006	AP	1	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N019386-004	AP	1	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N019386-005	AP	1	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N019386-006	AP	1	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N019386-004	AP	1	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N019386-005	AP	1	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N019386-006	AP	1	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N019386-004	AP	1	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N019386-005	AP	1	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N019386-006	AP	1	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N019386-004	AP	1	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N019386-005	AP	1	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N019386-006	AP	1	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N019386-004	AP	1	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N019386-005	AP	1	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N019386-006	AP	1	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N019386-004	AP	1	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N019386-005	AP	1	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N019386-006	AP	1	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N019386-004	AP	1	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	N019386-005	AP	1	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	N019386-006	AP	1	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N019386-004	AP	1	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N019386-005	AP	1	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N019386-006	AP	1	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N019386-004	AP	1	`301d65b070ca…`

Observed Orange Book patent history#

Patent history page 1 of 4 · 144 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Patent	Expiration	Coverage / status	Source SHA-256
2019-12-13 00:20 UTC	2019-12	N019386-004	6310094	2021-01-12		`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N019386-004	6528540	2021-01-12		`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N019386-004	6310094*PED	2021-07-12	Pediatric extension	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N019386-004	6528540*PED	2021-07-12	Pediatric extension	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N019386-005	6310094	2021-01-12		`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N019386-005	6528540	2021-01-12		`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N019386-005	6310094*PED	2021-07-12	Pediatric extension	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N019386-005	6528540*PED	2021-07-12	Pediatric extension	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N019386-006	6310094	2021-01-12		`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N019386-006	6528540	2021-01-12		`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N019386-006	6310094*PED	2021-07-12	Pediatric extension	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N019386-006	6528540*PED	2021-07-12	Pediatric extension	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N019386-007	6310094	2021-01-12		`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N019386-007	6528540	2021-01-12		`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N019386-007	6310094*PED	2021-07-12	Pediatric extension	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	N019386-007	6528540*PED	2021-07-12	Pediatric extension	`74a2ff9319b5…`
2021-12-28 21:50 UTC	2021-12	N019386-004	6310094	2021-01-12		`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	N019386-004	6528540	2021-01-12		`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	N019386-004	6310094*PED	2021-07-12	Pediatric extension	`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	N019386-004	6528540*PED	2021-07-12	Pediatric extension	`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	N019386-005	6310094	2021-01-12		`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	N019386-005	6528540	2021-01-12		`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	N019386-005	6310094*PED	2021-07-12	Pediatric extension	`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	N019386-005	6528540*PED	2021-07-12	Pediatric extension	`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	N019386-006	6310094	2021-01-12		`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	N019386-006	6528540	2021-01-12		`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	N019386-006	6310094*PED	2021-07-12	Pediatric extension	`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	N019386-006	6528540*PED	2021-07-12	Pediatric extension	`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	N019386-007	6310094	2021-01-12		`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	N019386-007	6528540	2021-01-12		`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	N019386-007	6310094*PED	2021-07-12	Pediatric extension	`782e0a99824c…`
2021-12-28 21:50 UTC	2021-12	N019386-007	6528540*PED	2021-07-12	Pediatric extension	`782e0a99824c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N019386-004	6310094	2021-01-12		`87673890dc5c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N019386-004	6528540	2021-01-12		`87673890dc5c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N019386-004	6310094*PED	2021-07-12	Pediatric extension	`87673890dc5c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N019386-004	6528540*PED	2021-07-12	Pediatric extension	`87673890dc5c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N019386-005	6310094	2021-01-12		`87673890dc5c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N019386-005	6528540	2021-01-12		`87673890dc5c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N019386-005	6310094*PED	2021-07-12	Pediatric extension	`87673890dc5c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N019386-005	6528540*PED	2021-07-12	Pediatric extension	`87673890dc5c…`

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Esmolol Hydrochloride	ESMOLOL HYDROCHLORIDE	Baxter Healthcare Corporation	f0a56c07-8f0f-4499-8d00-f13a966bf988	2023-06-15	Warnings, Adverse reactions	Exact identifier ndc (package): 10019-120-39 ndc11 (package): 10019012039

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.