Indications and uses
Use at the first sign of migraine or migraine-like headache
Use at the first sign of migraine or migraine-like headache
To open UnitDose dispenser, tear off the perforated end. Squeeze entire contents under the tongue. Important: Hold gel under the tongue for 60 seconds, then swallow. Repeat after 5 minutes using a second UnitDose dispenser. Avoid eating or drinking liquids for 15 minutes after each dose. An additional dose may be taken after 30 minutes. Take 1 or 2 UnitDose dispensers, as needed or as directed by a doctor
Clinical tests1 show that MigraPure provides advanced migraine pain relief
MigraPure's advanced formula is a first-line treatment for acute migraine pain.
MigraPure also relieves symptoms often associated with migraine.
With an excellent safety profile, MigraPure can be used by virtually all migraine sufferers.
MigraPure was originally tested as LipiGesic M, Patent #8,409,637
[1] Cady, RK, Goldstein J, Nett R, et al. A double-blind placebo-controlled pilot study of sublingual feverfew and ginger (LipiGesic™ M) in the treatment of migraine.
MigraPure absorbs under-the-tongue for fast results

MigraPure's patented delivery system is different than traditional medications.
Simply squeeze the contents of MigraPure's pre-measured UnitDose sachet under your tongue and hold it there for one minute.
MigraPure's full-strength feverfew and ginger gel absorbs directly into your bloodstream through he capillaries under your tongue. MigraPure starts to work immediately for ultra-fast relief.
Pill and capsules often lose 50 to 75 percent of their potency as they travel through the stomach and liver. It may take over an hour for relief.
“After not having any luck with even prescription medications, I decided to try it. Within seconds after putting it in my mouth, the migraines dissipate. Within a few minutes, the migraines disappear completely. “Stopping dead in it's tracks” is an understatement. I finally have gotten some relief. As great as this works, I would pay triple for. Thank you for such an incredible product. ~Garrett D
Does MigraPure cause side effects?
No serious adverse events were reported1. The few side effects recorded included body aches, stomach cramps, vomiting, oral tingling or numbness, heartburn and nausea.
What drugs interact with MigraPure?
There are no reported drug interactions with MigraPure. However, you should consult your healthcare provider if you are taking other medications.
Who should NOT take MigraPure?
Warning: If pregnant or breastfeeding, ask a healthcare professional before use.
Do not use if you have a known allergy or hypersensitivity to ragweed or other members of the Asteraceae family or any other ingredient. If a significant allergic reaction occurs, stop using the product and seek immediate medical help.
Ask a healthcare profession before use if:
DIRECTIONS
For maximum effectiveness, begin treatment at the first sign of headache.
Open one UnitDose dispenser by tearing off the perforated end and dispensing entire contents under the tongue. Important: Hold in place under the tongue for at least 60 seconds; then, swallow.
Repeat with second UnitDose after 5 minutes.
For maximum effectiveness: Don't eat or drink anything for at least 15 minutes after taking a UnitDose.
If needed or as directed by a doctor, an additional 1 or 2 UnitDose dispensers may be taken after 30 minutes.
Active Ingredients: Pyrethrum Parthenium [Feverfew] (3X), Zingiber Officinale [Ginger] (2X)
Other Ingredients: N.F. Grade Olive Oil, Silicon Dioxide, Peppermint Flavor
Indication: For relief of migraine and associated symptoms and migraine-like headaches such as sinus and hangover headaches.
Use only if UnitDose dispenser is intact.
__________________________
[2] Cady, RJ, Shade, CL, Cady RK. Advances in Drug Development for Acute Migraine.
Please keep this and all dugs out of the reach of children.
MigraPure is effective
MigraPure is unique

MigraPure is a homeopathic gel taken under the tongue. Full-strength active ingredients absorb directly into the blood stream to reach pain faster. Clinical trials show it is effective for 64 percent of migraines – at a fraction of the cost of prescriptions. MigraPure does not contain acetaminophen, aspirin, or caffeine or other chemical compounds.
“Advantages of this product include lower cost, OTC availability and it is not likely to produce medication-overuse headache. It is an excellent first-line therapy for very early intervention, as it is compatible with other acute treatment options.”
~ Roger K Cady, MD Headache expert and founder of the Headache Care Center
Cady RJ, Shade CL, Cady RK. Advances in Drug Development for Acute Migraine. Drugs 2012; 72 (17): 2187-2205
MigraPure is TOUGH on migraine and migraine-like headache, but easy on you
MigraPure's all natural formula is non-drowsy, non-habit forming and causes less stomach upset than convention migraine treatments.
MigraPure is easy to carry and easy to use. It is pre-measured so you can take it anywhere. You don't even need water.
MigraPure is easy on your wallet. MigraPure gives you the power of prescription strength in an over-the-counter formula, without the severe side effects and without the high cost.
MigraPure costs up to 75 percent less than the top-selling prescription migraine medication.
What are migraine-like headaches?
There are other types of headache pain that mimic migraine and can be successfully treated by MigraPure.
Hangover: The same type of pain-causing chemical cascade happens during a migraine that happens during a hangover. People have used MigraPure successfully to treat hangovers. The benefit of using MigraPure is that it does not have a negative impact on the liver.
Sinus pain: According to the American Migraine Study II, 9 out of 10 self-diagnosed sinus headaches are actually migraines. Migraines can cause pain and pressure in the forehead and sinus area.
A sinus headache, however, is accompanied by signs of infection such as discolored nasal discharge.
Migraines can last 4 to 72 hours – the pain doesn't have to.
Thank you for trying MigraPure.
If this is your first time trying our product, we would like to hear from you.
Send us your story and give us permission to use your MigraPure story as a testimonial, and we will send you a free box of MigraPure. (We'll only publish your first name, city and state.)
Contact us by email:
story@MigraPure.com
Contact us via our website:
www.MigraPure. com/story
Or send a letter to:
1326 Schofield Avenue
Schofield, WI 54476
Just be sure to tell us we have permission to use your story.
Your privacy is important to us. We will not share or sell your information.
PuraMed®
BioScience
Manufactured for
PuraMed BioScience, Inc.
P.O. Box 677, Schofield, WI 54476
www.MigraPure.com
877-851-2190 info@MigraPure.com
© PuraMed BioScience, Inc.® 2014
0215
DRUG FACTS
Feverfew (3X), Ginger (2X)
Relief of migraine pain and associated symptoms and migraine-like headaches such as sinus and hangover headache
Use at the first sign of migraine or migraine-like headache
If pregnant or breastfeeding, ask a healthcare professional before use.
Do not use if you have a known allergy or hypersensitivity to ragweed or other members of the Asteraceae family or any other ingredient. If a significant allergic reaction occurs, stop using the product and seek immediate medical help.
To open UnitDose dispenser, tear off the perforated end. Squeeze entire contents under the tongue.
Avoid eating or drinking liquids for 15 minutes after each dose.
Store at 20 - 60° C (68 - 120° F)
N.F. Grade Olive Oil, Silicon Dioxide, Peppermint Flavor
| NDC | Effective | Action | Document | Indexing SPL | Related label |
|---|---|---|---|---|---|
| 34331-302-04 | 2025-01-06 | C162847 | 48780-1 | 9d75b9d0-65da-f424-e053-dadaa90a57ce | MigraPure TM Advanced migraine relief |
| 34331-302-04 | 2020-01-31 | C162847 | 48780-1 | 9d75b9d0-65da-f424-e053-dadaa90a57ce | MigraPure TM Advanced migraine relief |
| Ingredient | Type | UNII | SPL version | Uploaded |
|---|---|---|---|---|
| feverfew | ACTIVE INGREDIENT | Z64FK7P217 | 1 | |
| Ginger | ACTIVE INGREDIENT | C5529G5JPQ | 1 | |
| feverfew | ACTIVE MOIETY | Z64FK7P217 | 1 | |
| Ginger | ACTIVE MOIETY | C5529G5JPQ | 1 | |
| Olive Oil | INACTIVE INGREDIENT | 6UYK2W1W1E | 1 | |
| Silicon Dioxide | INACTIVE INGREDIENT | ETJ7Z6XBU4 | 1 |
Every source-derived product name is available through these pages.
| Product NDC | Package NDC |
|---|---|
| 34331-302 | 34331-302-04 |
Every source-derived ingredient row is available through these pages.
| Name | UNII | Kind |
|---|---|---|
| feverfew | Z64FK7P217 | ACTIB |
| Ginger | C5529G5JPQ | ACTIB |
| Olive Oil | 6UYK2W1W1E | IACT |
| Silicon Dioxide | ETJ7Z6XBU4 | IACT |
Inactive Ingredient Database values describe FDA-listed use contexts. The match method and ambiguity count are shown because ingredient names, routes, and dosage forms are not always unique. Browse recovered IID releases and source provenance.
| DailyMed ingredient | IID ingredient | UNII | Dosage form / route | Potency | Maximum daily exposure | Match |
|---|---|---|---|---|---|---|
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | CREAM / VAGINAL | 51 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | CAPSULE, COATED, EXTENDED RELEASE / ORAL | NA | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | INSERT / VAGINAL | 8 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | PELLET / ORAL | 34 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | CAPSULE, LIQUID FILLED / ORAL | 106 mg | ||
| Olive Oil | OLIVE OIL | 6UYK2W1W1E | SOLUTION / ORAL | 425 mg/1ml | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | GEL / TOPICAL | 6 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | TABLET, EXTENDED RELEASE / ORAL | 450 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | TABLET, COATED / ORAL | 176 mg | ||
| Olive Oil | OLIVE OIL | 6UYK2W1W1E | SOAP / TOPICAL | NA | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | CAPSULE, COATED / ORAL | 3 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | GRANULE / ORAL | 5000 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | CAPSULE, DELAYED RELEASE / ORAL | 40 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | GRANULE, FOR SUSPENSION, EXTENDED RELEASE / ORAL | NA | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | TAMPON / VAGINAL | NA | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | GRANULE, FOR SOLUTION / ORAL | 1.8 mg/120ml | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | TABLET, CHEWABLE / ORAL | 254 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | LOZENGE / ORAL | 120 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | CAPSULE, EXTENDED RELEASE / ORAL | 168 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | POWDER, FOR SUSPENSION / ORAL | 2553 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | GEL / DENTAL | 19 %w/w | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | TABLET, DELAYED RELEASE / ORAL | 1190 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | CAPSULE, COATED PELLETS / ORAL | 69 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | TABLET / BUCCAL | 3 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | GRANULE, DELAYED RELEASE / ORAL | 3.2 mg | ||
| Olive Oil | OLIVE OIL | 6UYK2W1W1E | SOLUTION / TOPICAL | 0.6 %w/w | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | POWDER / ORAL | 602 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | TABLET, FOR SUSPENSION / ORAL | 220 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | TABLET / ORAL | 750 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | TABLET, DELAYED RELEASE PARTICLES / ORAL | 170 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | CAPSULE / ORAL | 300 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | SYSTEM / TRANSDERMAL | 35 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | GRANULE, FOR SUSPENSION / ORAL | 200 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | SUSPENSION / ORAL | 400 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | POWDER, FOR SOLUTION / ORAL | 280 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | GEL / NASAL | 20 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | TABLET, ORALLY DISINTEGRATING / ORAL | 68 mg | ||
| Olive Oil | OLIVE OIL | 6UYK2W1W1E | LOTION / TOPICAL | 32468 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | SUPPOSITORY / RECTAL | 14 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | CAPSULE / RESPIRATORY (INHALATION) | NA | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | GEL / VAGINAL | 8 %w/w | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | TABLET, FILM COATED, EXTENDED RELEASE / ORAL | 336 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | TABLET, CHEWABLE, EXTENDED RELEASE / ORAL | 2 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | PASTE / DENTAL | 34 %w/w | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | FILM, SOLUBLE / ORAL | 2 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | POWDER / RESPIRATORY (INHALATION) | NA | ||
| Olive Oil | OLIVE OIL | 6UYK2W1W1E | CAPSULE / ORAL | NA | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | TABLET, FILM COATED / ORAL | 166 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | SOLUTION / ORAL | 336 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | FILM, EXTENDED RELEASE / TRANSDERMAL | 49 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | TABLET / SUBLINGUAL | 10 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | DROPS / ORAL | NA | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | SUSPENSION, EXTENDED RELEASE / ORAL | 70 mg | ||
| Silicon Dioxide | SILICON DIOXIDE | ETJ7Z6XBU4 | TABLET, ORALLY DISINTEGRATING, DELAYED RELEASE / ORAL | 69 mg |
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| 2b109f1a-9009-3e30-e063-6294a90afddd | 3595fe4f-1b85-4c27-aa22-912a27159055 | 2025-01-06 | Warnings | 3595fe4f-1b85-4c27-aa22-912a27159055 |
Adverse event summaries are temporarily unavailable. Other product information remains available.