Cold-EEZE

Manufacturer: ProPhase Labs, Inc. | Pharmaloz Manufacturing, Inc.
Effective date: 2011-03-30
Label type: HUMAN OTC DRUG LABEL
Version: 1
Source: full-release
Hydrated at: 2026-06-01 02:03:10

Label at a glance#

ProductCold-EEZE

Active ingredientZinc Gluconate

Label structure11 sections

Indications and uses

to reduce the duration of the common cold reduces the severity of cold symptoms: cough, sore throat, stuffy nose, sneezing, post nasal drip and/or hoarseness

Dosage and administration

adults and children 12 years and over for best results, begin treatment at start of symptoms (within 24-48 hours of onset) repeat every 2 - 4 hours as needed until all symptoms subside completely dissolve a COLD-EEZE® lozenge in mouth (do not chew) recommended daily dosage is 6 lozenges for adults and 4 lozenges for ages 12-17 children under 12 years of age should consult a health professional prior to use

Storage and handling

avoid minor stomach upset - Do not dissolve COLD-EEZE® lozenges on an empty stomach avoid citrus fruits or juices and products containing citric acid 1/2 hour before or after taking COLD-EEZE® lozenges as they may diminish product effectiveness, otherwise, drink plenty of fluids store in a cool dry place after opening gluten-free

Contacts and useful links#

PhoneLabel contact1-800-505-COLD

Label contents#

Full prescribing information#

SPL UNCLASSIFIED SECTION

Drug Facts

Active ingredient (per lozenge)

OTC - ACTIVE INGREDIENT SECTION

Zincum Gluconicum 2x (13.3mg)

Purpose

OTC - PURPOSE SECTION

Cold Remedy

Uses

INDICATIONS & USAGE SECTION

to reduce the duration of the common cold
reduces the severity of cold symptoms: cough, sore throat, stuffy nose, sneezing, post nasal drip and/or hoarseness

Warnings

WARNINGS SECTION

Ask a doctor before use if you

OTC - ASK DOCTOR SECTION

are taking minocycline, doxycycline, tetracycline or are on coumadin therapy, zinc treatment may inhibit the absorption of these medicines

OTC - STOP USE SECTION

Stop use and ask your healthcare practitioner if symptoms persist beyond 7 days.

OTC - WHEN USING SECTION

COLD-EEZE® Lozenges are formulated to reduce the duration of common cold symptoms and may be insufficient treatment for Influenza or Allergies.

OTC - PREGNANCY OR BREAST FEEDING SECTION

If pregnant or breast-feeding, ask a health professional before use.

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

Keep out of reach of children.

Directions

DOSAGE & ADMINISTRATION SECTION

adults and children 12 years and over
for best results, begin treatment at start of symptoms (within 24-48 hours of onset)
repeat every 2 - 4 hours as needed until all symptoms subside
completely dissolve a COLD-EEZE® lozenge in mouth (do not chew)
recommended daily dosage is 6 lozenges for adults and 4 lozenges for ages 12-17
children under 12 years of age should consult a health professional prior to use

Other information

STORAGE AND HANDLING SECTION

avoid minor stomach upset - Do not dissolve COLD-EEZE® lozenges on an empty stomach
avoid citrus fruits or juices and products containing citric acid 1/2 hour before or after taking COLD-EEZE® lozenges as they may diminish product effectiveness, otherwise, drink plenty of fluids
store in a cool dry place after opening
gluten-free

Inactive ingredients

INACTIVE INGREDIENT SECTION

corn syrup, honey, glycine, natural flavors and sucrose. No artificial colors or preservatives.

Questions or Comments

OTC - QUESTIONS SECTION

Call 1-800-505-COLD
(9AM-5PM EST)

PRINCIPAL DISPLAY PANEL - 18 Lozenge Package

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

GREAT
NEW TASTE

Cold-EEZE^®
Zinc Gluconate Glycine

COLD REMEDY

OTC Master's Circle
Achievement Award
#1
Pharmacist
Recommended
Brand!
Pharmacy
Times

Clinically proven to reduce the
duration of the common cold^®
#1 Pharmacist Recommended
Shortens your cold, works fast

18
Cold Remedy
Lozenges

Homeopathic

All Natural
Honey Lemon Flavor
with other natural flavors

Principal Display Panel - 18 Lozenge Package

PRINCIPAL DISPLAY PANEL - 24 Lozenge Package

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

GREAT
NEW TASTE

Cold-EEZE^®
Zinc Gluconate Glycine

33%
MORE
FREE

COLD REMEDY

OTC Master's Circle
Achievement Award
#1
Pharmacist
Recommended
Brand!
Pharmacy
Times

Clinically proven to reduce the
duration of the common cold^®
#1 Pharmacist Recommended
Shortens your cold, works fast

24
Cold Remedy
Lozenges

Homeopathic

All Natural
Honey Lemon Flavor
with other natural flavors

Principal Display Panel - 24 Lozenge Package

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
0ca1d589-929b-4b33-bc5b-1d84abdafa6a	Product name	1	20150324
fc363c46-397b-4476-ac0f-70e43e8e4592	Product name	1	20150324

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDC	Effective	Action	Document	Indexing SPL	Related label
61941-0021-1	2020-01-31	C162847	48780-1	9d75b9d0-fb2c-f424-e053-dadaa90a57ce	Cold-EEZE ® Honey Lemon
61941-0021-2	2020-01-31	C162847	48780-1	9d75b9d0-fb2c-f424-e053-dadaa90a57ce	Cold-EEZE ® Honey Lemon
61941-0021-3	2020-01-31	C162847	48780-1	9d75b9d0-fb2c-f424-e053-dadaa90a57ce	Cold-EEZE ® Honey Lemon
61941-0022-4	2020-01-31	C162847	48780-1	9d75b9d0-fb2c-f424-e053-dadaa90a57ce	Cold-EEZE ® Honey Lemon

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
61941-0021-1	Cold-EEZE	24 in 1 CASE	LOZENGE	24	1
61941-0021-2	Cold-EEZE	48 in 1 CASE	LOZENGE	48	1
61941-0021-3	Cold-EEZE	144 in 1 CASE	LOZENGE	144	1
61941-0021-8	Cold-EEZE	18 in 1 PACKAGE	LOZENGE	18	1
61941-0022-4	Cold-EEZE	24 in 1 PACKAGE	LOZENGE	24	1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
61941-0021	COLD-EEZE (ZINC GLUCONATE) LOZENGE [PROPHASE LABS, INC.]	1	Legacy NDC, 4 package rows	20110531_c7bb8434-9ed1-46e3-9854-875f9db3a24a.zip
61941-0022	COLD-EEZE (ZINC GLUCONATE) LOZENGE [PROPHASE LABS, INC.]	1	Legacy NDC, 1 package rows	20110531_c7bb8434-9ed1-46e3-9854-875f9db3a24a.zip

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	SPL version
Zinc Gluconate	ACTIVE INGREDIENT	U6WSN5SQ1Z	1
Zinc	ACTIVE MOIETY	J41CSQ7QDS	1
Corn Syrup	INACTIVE INGREDIENT	9G5L16BK6N	1
Glycine	INACTIVE INGREDIENT	TE7660XO1C	1
Honey	INACTIVE INGREDIENT	Y9H1V576FH	1
Sucrose	INACTIVE INGREDIENT	C151H8M554	1

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 7 matching rows.

Cold-EEZE
Zinc Gluconate
Zinc
Corn Syrup
Glycine
Sucrose
Honey

NDC Codes#

Product NDC, Package NDC table
Product NDC	Package NDC
61941-0021	61941-0021-8, 61941-0021-1, 61941-0021-2, 61941-0021-3
61941-0022	61941-0022-4

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 10 matching rows.

Name, UNII, Kind table
Name	UNII	Kind
Zinc Gluconate	U6WSN5SQ1Z	ACTIB
Corn Syrup	9G5L16BK6N	IACT
Glycine	TE7660XO1C	IACT
Sucrose	C151H8M554	IACT
Honey	Y9H1V576FH	IACT
Zinc Gluconate	U6WSN5SQ1Z	ACTIB
Corn Syrup	9G5L16BK6N	IACT
Glycine	TE7660XO1C	IACT
Sucrose	C151H8M554	IACT
Honey	Y9H1V576FH	IACT

Source Document#

Source XML · Source PDF

Inactive ingredient matches#

Inactive Ingredient Database values describe FDA-listed use contexts. The match method and ambiguity count are shown because ingredient names, routes, and dosage forms are not always unique. Browse recovered IID releases and source provenance.

Inactive ingredient links page 1 of 2 · 78 matching rows.

DailyMed ingredient, IID ingredient, UNII table
DailyMed ingredient	IID ingredient	UNII	Dosage form / route	Potency	Maximum daily exposure	Match
Sucrose	SUCROSE	C151H8M554	GRANULE / ORAL	NA		Exact identifier — unii candidate 48 equally ranked IID candidates
Glycine	GLYCINE	TE7660XO1C	TABLET, ORALLY DISINTEGRATING / ORAL		60 mg	Exact identifier — unii candidate 20 equally ranked IID candidates
Glycine	GLYCINE	TE7660XO1C	INJECTABLE, LIPOSOMAL / INTRAVENOUS	0.38 %w/v		Exact identifier — unii candidate 20 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	CONCENTRATE / ORAL		4800 mg	Exact identifier — unii candidate 48 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	SUPPOSITORY / RECTAL	NA		Exact identifier — unii candidate 48 equally ranked IID candidates
Corn Syrup	CORN SYRUP	9G5L16BK6N	ELIXIR / ORAL	400 mg/1ml		Exact identifier — unii candidate 10 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION / INTRAVENOUS		2000 mg	Exact identifier — unii candidate 48 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	PASTILLE / ORAL	426 mg		Exact identifier — unii candidate 48 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	TROCHE / ORAL	NA		Exact identifier — unii candidate 48 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	POWDER / ORAL		27768 mg	Exact identifier — unii candidate 48 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	INJECTION, SUSPENSION, LIPOSOMAL / INTRAVENOUS	9.4 %w/v		Exact identifier — unii candidate 48 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	TABLET, FILM COATED, EXTENDED RELEASE / ORAL	119.12 mg		Exact identifier — unii candidate 48 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	POWDER, FOR SOLUTION / ORAL		38666 mg	Exact identifier — unii candidate 48 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	ELIXIR / ORAL		18000 mg	Exact identifier — unii candidate 48 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	TABLET, CHEWABLE / ORAL		7258 mg	Exact identifier — unii candidate 48 equally ranked IID candidates
Glycine	GLYCINE	TE7660XO1C	INJECTION, SOLUTION / INTRAVENOUS	0.42 %w/v		Exact identifier — unii candidate 20 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	GRANULE, FOR SUSPENSION / ORAL		31885 mg	Exact identifier — unii candidate 48 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	INJECTION, POWDER, FOR SUSPENSION / INTRAVENOUS	900 mg		Exact identifier — unii candidate 48 equally ranked IID candidates
Glycine	GLYCINE	TE7660XO1C	INJECTION / INTRAVENOUS	200 mg		Exact identifier — unii candidate 20 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	TABLET, DELAYED RELEASE / ORAL	295.33 mg		Exact identifier — unii candidate 48 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	SUSPENSION / ORAL		48209 mg	Exact identifier — unii candidate 48 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	POWDER, FOR SUSPENSION / ORAL		40017 mg	Exact identifier — unii candidate 48 equally ranked IID candidates
Glycine	GLYCINE	TE7660XO1C	CAPSULE, DELAYED RELEASE / ORAL		50 mg	Exact identifier — unii candidate 20 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	SOLUTION / RECTAL	35.42 %w/v		Exact identifier — unii candidate 48 equally ranked IID candidates
Glycine	GLYCINE	TE7660XO1C	TABLET, CHEWABLE / ORAL		267 mg	Exact identifier — unii candidate 20 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	INJECTION, EMULSION / INTRAVENOUS		970 mg	Exact identifier — unii candidate 48 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	LIQUID / ORAL		37500 mg	Exact identifier — unii candidate 48 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	INJECTION / INTRAVENOUS		1950 mg	Exact identifier — unii candidate 48 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	TABLET, FILM COATED / ORAL		145 mg	Exact identifier — unii candidate 48 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	LOZENGE / TRANSMUCOSAL		1255 mg	Exact identifier — unii candidate 48 equally ranked IID candidates
Corn Syrup	CORN SYRUP	9G5L16BK6N	TABLET, COATED / ORAL	17 mg		Exact identifier — unii candidate 10 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	GRANULE, FOR SOLUTION / ORAL		42596 mg	Exact identifier — unii candidate 48 equally ranked IID candidates
Glycine	GLYCINE	TE7660XO1C	SOLUTION / ORAL	50 mg		Exact identifier — unii candidate 20 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	CAPSULE, COATED, EXTENDED RELEASE / ORAL		86 mg	Exact identifier — unii candidate 48 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	GRANULE, FOR SUSPENSION, EXTENDED RELEASE / ORAL		18790 mg	Exact identifier — unii candidate 48 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	TROCHE / BUCCAL	NA		Exact identifier — unii candidate 48 equally ranked IID candidates
Corn Syrup	CORN SYRUP	9G5L16BK6N	SOLUTION / ORAL	750 mg/5ml		Exact identifier — unii candidate 10 equally ranked IID candidates
Glycine	GLYCINE	TE7660XO1C	CAPSULE / ORAL		62 mg	Exact identifier — unii candidate 20 equally ranked IID candidates
Glycine	GLYCINE	TE7660XO1C	INJECTION / INTRAMUSCULAR		68 mg	Exact identifier — unii candidate 20 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	SUSPENSION/ DROPS / ORAL		3750 mg	Exact identifier — unii candidate 48 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	TABLET, EXTENDED RELEASE / ORAL	284.54 mg		Exact identifier — unii candidate 48 equally ranked IID candidates
Glycine	GLYCINE	TE7660XO1C	INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION / INTRAVENOUS	200 mg		Exact identifier — unii candidate 20 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	SYRUP / ORAL		46400 mg	Exact identifier — unii candidate 48 equally ranked IID candidates
Glycine	GLYCINE	TE7660XO1C	PASTE, DENTIFRICE / DENTAL	0.34 %w/w		Exact identifier — unii candidate 20 equally ranked IID candidates
Corn Syrup	CORN SYRUP	9G5L16BK6N	TROCHE / ORAL	NA		Exact identifier — unii candidate 10 equally ranked IID candidates
Glycine	GLYCINE	TE7660XO1C	INJECTION, POWDER, FOR SOLUTION / INTRAMUSCULAR	40 mg		Exact identifier — unii candidate 20 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	INJECTABLE, LIPOSOMAL / INTRAVENOUS		7560 mg	Exact identifier — unii candidate 48 equally ranked IID candidates
Corn Syrup	CORN SYRUP	9G5L16BK6N	TABLET / ORAL	14.07 mg		Exact identifier — unii candidate 10 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	TABLET / SUBLINGUAL	109 mg		Exact identifier — unii candidate 48 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	SOLUTION / ORAL		70000 mg	Exact identifier — unii candidate 48 equally ranked IID candidates
Glycine	GLYCINE	TE7660XO1C	INJECTION, POWDER, FOR SOLUTION / INTRADERMAL	0.5 mg		Exact identifier — unii candidate 20 equally ranked IID candidates
Glycine	GLYCINE	TE7660XO1C	INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION / SUBCUTANEOUS	10 mg		Exact identifier — unii candidate 20 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	TABLET, COATED / ORAL	516.42 mg		Exact identifier — unii candidate 48 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	LOZENGE / BUCCAL	NA		Exact identifier — unii candidate 48 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	DROPS / ORAL	NA		Exact identifier — unii candidate 48 equally ranked IID candidates
Corn Syrup	CORN SYRUP	9G5L16BK6N	SUSPENSION, EXTENDED RELEASE / ORAL	1500 mg/5ml		Exact identifier — unii candidate 10 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION / SUBCUTANEOUS		308 mg	Exact identifier — unii candidate 48 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	TABLET / ORAL		4249 mg	Exact identifier — unii candidate 48 equally ranked IID candidates
Glycine	GLYCINE	TE7660XO1C	INJECTION, POWDER, FOR SOLUTION / INTRAVENOUS	3.76 mg		Exact identifier — unii candidate 20 equally ranked IID candidates
Sucrose	SUCROSE	C151H8M554	SUSPENSION, EXTENDED RELEASE / ORAL		5400 mg	Exact identifier — unii candidate 48 equally ranked IID candidates

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
302a8a5e-b5d2-4820-a3b4-fc83310cb114			c7bb8434-9ed1-46e3-9854-875f9db3a24a	2011-03-30	Warnings	Exact identifier spl id: 302a8a5e-b5d2-4820-a3b4-fc83310cb114 spl set id: c7bb8434-9ed1-46e3-9854-875f9db3a24a

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.