AVOBENZONE and OCTISALATE

Manufacturer: CLINIQUE LABORATORIES LLC | ESTEE LAUDER COMPANY, THE | ESTEE LAUDER COSMETICS, LTD | ESTEE LAUDER COSMETICS, LTD. | ESTEE LAUDER N.V. | LEN-RON MANUFACTURING DIVISION OF ARAMIS INC | NORTHTEC INC | PADC 1 | WHITMAN LABORATORIES, LTD.
Effective date: 2019-11-14
Label type: HUMAN OTC DRUG LABEL
Version: 3
Source: legacy-cache
Hydrated at: 2026-08-02 00:01:04

Label at a glance#

ProductSUPERDEFENSE DAILY DEFENSE MOISTURIZER BROAD SPECTRUM SPF20 (VERY DRY - DRY COMB)

Active ingredientAVOBENZONE, OCTISALATE

Label structure9 sections

Dosage and administration

apply liberally 15 minutes before sun exposure reapply at least every two hours use a water resistant sunscreen if swimming or sweating Sun Protection Measures. Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a Broad Spectrum SPF value of 15 or higher and other sun protection measures including: limit time in the sun, especiall...

Storage and handling

protect the product in this container from excessive heat and direct sun

Label contents#

Full prescribing information#

SPL UNCLASSIFIED SECTION

Drug Facts

Active ingredients

OTC - ACTIVE INGREDIENT SECTION

Avobenzone 3.0%
Octisalate 5.0%

Purpose

OTC - PURPOSE SECTION

Sunscreen

Use

INDICATIONS & USAGE SECTION

helps prevent sunburn

Warnings

WARNINGS SECTION

SPL UNCLASSIFIED SECTION

For external use only

OTC - DO NOT USE SECTION

Do not use on damaged or broken skin

OTC - WHEN USING SECTION

When using this product keep out of eyes. Rinse with water to remove.

OTC - STOP USE SECTION

Stop use and ask a doctor if rash occurs

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

Keep out of reach of children. If product is swallowed, get medical help or contact a Poison Control Center right away.

Directions

DOSAGE & ADMINISTRATION SECTION

apply liberally 15 minutes before sun exposure
reapply at least every two hours
use a water resistant sunscreen if swimming or sweating
Sun Protection Measures. Spending time in the sun increases your risk of skin cancer and early skin aging. To decrease this risk, regularly use a sunscreen with a Broad Spectrum SPF value of 15 or higher and other sun protection measures including:
- limit time in the sun, especially from 10 a.m. – 2 p.m.
- wear long-sleeved shirts, pants, hats and sunglasses
children under 6 months of age: ask a doctor

Inactive ingredients

INACTIVE INGREDIENT SECTION

water\aqua\eau • butyrospermum parkii (shea butter) • butyloctyl salicylate • dimethicone • petrolatum • polyester-8 • cetearyl alcohol • glyceryl stearate • peg-100 stearate • butylene glycol • glycerin • trehalose • sigesbeckia orientalis (st. paul's wort) extract • hordeum vulgare (barley) extract\extrait d'orge • triticum vulgare (wheat) germ extract • arabidopsis thaliana extract • plankton extract • algae extract • sea whip extract • lactobacillus ferment • micrococcus lysate • ergothioneine • caffeine • lecithin • sodium hyaluronate • isohexadecane • potassium cetyl phosphate • tocopheryl acetate • ethylhexylglycerin • squalane • caprylyl glycol • acrylamide/sodium acryloyldimethyltaurate copolymer • acrylates/c10-30 alkyl acrylate crosspolymer • polyethylene • tetrahexyldecyl ascorbate • dimethiconol • polysorbate 80 • zeolite • xanthan gum • pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate • tromethamine • disodium edta • phenoxyethanol [iln39713]

Other information

STORAGE AND HANDLING SECTION

protect the product in this container from excessive heat and direct sun

PRINCIPAL DISPLAY PANEL - 50 ml Jar Carton

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

age prevention

CLINIQUE

superdefense

daily defense moisturizer
broad spectrum SPF 20

VERY DRY TO DRY COMBINATION

POIDS NET WT. 1.7 OZ./50 ml e

Principal Display Panel - 50 ml Jar Carton

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	SPL version
AVOBENZONE	ACTIVE INGREDIENT	G63QQF2NOX	1
OCTISALATE	ACTIVE INGREDIENT	4X49Y0596W	1
AVOBENZONE	ACTIVE MOIETY	G63QQF2NOX	1
OCTISALATE	ACTIVE MOIETY	4X49Y0596W	1
.alpha.-tocopherol acetate	INACTIVE INGREDIENT	9E8X80D2L0	1
BARLEY	INACTIVE INGREDIENT	5PWM7YLI7R	1
butylene glycol	INACTIVE INGREDIENT	3XUS85K0RA	1
butyloctyl salicylate	INACTIVE INGREDIENT	2EH13UN8D3	1
caffeine	INACTIVE INGREDIENT	3G6A5W338E	1
caprylyl glycol	INACTIVE INGREDIENT	00YIU5438U	1
cetostearyl alcohol	INACTIVE INGREDIENT	2DMT128M1S	1
dimethicone	INACTIVE INGREDIENT	92RU3N3Y1O	1
edetate disodium	INACTIVE INGREDIENT	7FLD91C86K	1
ergothioneine	INACTIVE INGREDIENT	BDZ3DQM98W	1
ethylhexylglycerin	INACTIVE INGREDIENT	147D247K3P	1
glycerin	INACTIVE INGREDIENT	PDC6A3C0OX	1
glyceryl monostearate	INACTIVE INGREDIENT	230OU9XXE4	1
high density polyethylene	INACTIVE INGREDIENT	UG00KM4WR7	1
hyaluronate sodium	INACTIVE INGREDIENT	YSE9PPT4TH	1
isohexadecane	INACTIVE INGREDIENT	918X1OUF1E	1
peg-100 stearate	INACTIVE INGREDIENT	YD01N1999R	1
pentaerythritol tetrakis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate)	INACTIVE INGREDIENT	255PIF62MS	1
petrolatum	INACTIVE INGREDIENT	4T6H12BN9U	1
phenoxyethanol	INACTIVE INGREDIENT	HIE492ZZ3T	1
polysorbate 80	INACTIVE INGREDIENT	6OZP39ZG8H	1
potassium cetyl phosphate	INACTIVE INGREDIENT	03KCY6P7UT	1
pseudopterogorgia elisabethae	INACTIVE INGREDIENT	UDY3H1OUX5	1
SHEA BUTTER	INACTIVE INGREDIENT	K49155WL9Y	1
squalane	INACTIVE INGREDIENT	GW89575KF9	1
tetrahexyldecyl ascorbate	INACTIVE INGREDIENT	9LBV3F07AZ	1
trehalose	INACTIVE INGREDIENT	B8WCK70T7I	1
tromethamine	INACTIVE INGREDIENT	023C2WHX2V	1
water	INACTIVE INGREDIENT	059QF0KO0R	1
WHEAT GERM	INACTIVE INGREDIENT	YR3G369F5A	1
xanthan gum	INACTIVE INGREDIENT	TTV12P4NEE	1

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 35 matching rows.

SUPERDEFENSE DAILY DEFENSE MOISTURIZER BROAD SPECTRUM SPF20 (VERY DRY - DRY COMB)
AVOBENZONE and OCTISALATE
AVOBENZONE
OCTISALATE
water
SHEA BUTTER
butyloctyl salicylate
dimethicone
petrolatum
cetostearyl alcohol
glyceryl monostearate
peg-100 stearate
butylene glycol
glycerin
trehalose
BARLEY
WHEAT GERM
pseudopterogorgia elisabethae
ergothioneine
caffeine
hyaluronate sodium
isohexadecane
potassium cetyl phosphate
.alpha.-tocopherol acetate
ethylhexylglycerin
squalane
caprylyl glycol
high density polyethylene
tetrahexyldecyl ascorbate
polysorbate 80
xanthan gum
pentaerythritol tetrakis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate)
tromethamine
edetate disodium
phenoxyethanol

NDC Codes#

Product NDC, Package NDC table
Product NDC	Package NDC
49527-039	49527-039-01

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 33 matching rows.

Name, UNII, Kind table
Name	UNII	Kind
AVOBENZONE	G63QQF2NOX	ACTIB
OCTISALATE	4X49Y0596W	ACTIB
water	059QF0KO0R	IACT
SHEA BUTTER	K49155WL9Y	IACT
butyloctyl salicylate	2EH13UN8D3	IACT
dimethicone	92RU3N3Y1O	IACT
petrolatum	4T6H12BN9U	IACT
cetostearyl alcohol	2DMT128M1S	IACT
glyceryl monostearate	230OU9XXE4	IACT
peg-100 stearate	YD01N1999R	IACT
butylene glycol	3XUS85K0RA	IACT
glycerin	PDC6A3C0OX	IACT
trehalose	B8WCK70T7I	IACT
BARLEY	5PWM7YLI7R	IACT
WHEAT GERM	YR3G369F5A	IACT
pseudopterogorgia elisabethae	UDY3H1OUX5	IACT
ergothioneine	BDZ3DQM98W	IACT
caffeine	3G6A5W338E	IACT
hyaluronate sodium	YSE9PPT4TH	IACT
isohexadecane	918X1OUF1E	IACT
potassium cetyl phosphate	03KCY6P7UT	IACT
.alpha.-tocopherol acetate	9E8X80D2L0	IACT
ethylhexylglycerin	147D247K3P	IACT
squalane	GW89575KF9	IACT
caprylyl glycol	00YIU5438U	IACT
high density polyethylene	UG00KM4WR7	IACT
tetrahexyldecyl ascorbate	9LBV3F07AZ	IACT
polysorbate 80	6OZP39ZG8H	IACT
xanthan gum	TTV12P4NEE	IACT
pentaerythritol tetrakis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate)	255PIF62MS	IACT
tromethamine	023C2WHX2V	IACT
edetate disodium	7FLD91C86K	IACT
phenoxyethanol	HIE492ZZ3T	IACT

Source Document#

Source XML

Inactive ingredient matches#

Inactive Ingredient Database values describe FDA-listed use contexts. The match method and ambiguity count are shown because ingredient names, routes, and dosage forms are not always unique. Browse recovered IID releases and source provenance.

Inactive ingredient links page 1 of 7 · 381 matching rows.

DailyMed ingredient, IID ingredient, UNII table
DailyMed ingredient	IID ingredient	UNII	Dosage form / route	Potency	Maximum daily exposure	Match
squalane	SQUALANE	GW89575KF9	POWDER / ORAL	0.02 mg		Exact identifier — unii candidate 5 equally ranked IID candidates
squalane	SQUALANE	GW89575KF9	CREAM, AUGMENTED / TOPICAL		120 mg	Exact identifier — unii candidate 5 equally ranked IID candidates
edetate disodium	EDETATE DISODIUM	7FLD91C86K	SOLUTION / RESPIRATORY (INHALATION)		43 mg	Exact identifier — unii candidate 77 equally ranked IID candidates
glycerin	GLYCERIN	PDC6A3C0OX	LIQUID / TOPICAL	2.5 %w/w		Exact identifier — unii candidate 75 equally ranked IID candidates
xanthan gum	XANTHAN GUM	TTV12P4NEE	LOTION / TOPICAL	0.3 %w/v		Exact identifier — unii candidate 29 equally ranked IID candidates
edetate disodium	EDETATE DISODIUM	7FLD91C86K	INJECTION, POWDER, FOR SOLUTION / INTRAVENOUS		6 mg	Exact identifier — unii candidate 77 equally ranked IID candidates
polysorbate 80	POLYSORBATE 80	6OZP39ZG8H	SOLUTION, GEL FORMING, EXTENDED RELEASE / OPHTHALMIC	0.05 %w/w		Exact identifier — unii candidate 78 equally ranked IID candidates
edetate disodium	EDETATE DISODIUM	7FLD91C86K	TABLET, CHEWABLE / ORAL		1 mg	Exact identifier — unii candidate 77 equally ranked IID candidates
xanthan gum	XANTHAN GUM	TTV12P4NEE	SUSPENSION / ORAL		360 mg	Exact identifier — unii candidate 29 equally ranked IID candidates
edetate disodium	EDETATE DISODIUM	7FLD91C86K	SPRAY / NASAL		1 mg	Exact identifier — unii candidate 77 equally ranked IID candidates
edetate disodium	EDETATE DISODIUM	7FLD91C86K	GEL / TOPICAL		24 mg	Exact identifier — unii candidate 77 equally ranked IID candidates
glycerin	GLYCERIN	PDC6A3C0OX	TABLET / PERIODONTAL	0.53 mg		Exact identifier — unii candidate 75 equally ranked IID candidates
edetate disodium	EDETATE DISODIUM	7FLD91C86K	SUSPENSION/ DROPS / ORAL		4 mg	Exact identifier — unii candidate 77 equally ranked IID candidates
edetate disodium	EDETATE DISODIUM	7FLD91C86K	TABLET, EXTENDED RELEASE / ORAL		10 mg	Exact identifier — unii candidate 77 equally ranked IID candidates
edetate disodium	EDETATE DISODIUM	7FLD91C86K	INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION / INTRAVENOUS		19 mg	Exact identifier — unii candidate 77 equally ranked IID candidates
glycerin	GLYCERIN	PDC6A3C0OX	FILM, EXTENDED RELEASE / BUCCAL		34 mg	Exact identifier — unii candidate 75 equally ranked IID candidates
petrolatum	PETROLATUM	4T6H12BN9U	CAPSULE / VAGINAL	NA		Exact identifier — unii candidate 18 equally ranked IID candidates
.alpha.-tocopherol acetate	.ALPHA.-TOCOPHEROL ACETATE	9E8X80D2L0	CAPSULE / ORAL	2 mg		Exact identifier — unii candidate 3 equally ranked IID candidates
polysorbate 80	POLYSORBATE 80	6OZP39ZG8H	CAPSULE, COATED PELLETS / ORAL	2 mg		Exact identifier — unii candidate 78 equally ranked IID candidates
glyceryl monostearate	GLYCERYL MONOSTEARATE	230OU9XXE4	TABLET, CHEWABLE / ORAL		1 mg	Exact identifier — unii candidate 21 equally ranked IID candidates
polysorbate 80	POLYSORBATE 80	6OZP39ZG8H	SUSPENSION / SUBCUTANEOUS	0.3 %w/v		Exact identifier — unii candidate 78 equally ranked IID candidates
polysorbate 80	POLYSORBATE 80	6OZP39ZG8H	INJECTION, SOLUTION / INTRAMUSCULAR	5 %w/v		Exact identifier — unii candidate 78 equally ranked IID candidates
glyceryl monostearate	GLYCERYL MONOSTEARATE	230OU9XXE4	TABLET, ORALLY DISINTEGRATING, DELAYED RELEASE / ORAL		23 mg	Exact identifier — unii candidate 21 equally ranked IID candidates
phenoxyethanol	PHENOXYETHANOL	HIE492ZZ3T	CREAM, AUGMENTED / TOPICAL		10 mg	Exact identifier — unii candidate 6 equally ranked IID candidates
xanthan gum	XANTHAN GUM	TTV12P4NEE	GEL / TOPICAL		58 mg	Exact identifier — unii candidate 29 equally ranked IID candidates
polysorbate 80	POLYSORBATE 80	6OZP39ZG8H	AEROSOL, FOAM / VAGINAL	3 %w/w		Exact identifier — unii candidate 78 equally ranked IID candidates
polysorbate 80	POLYSORBATE 80	6OZP39ZG8H	TABLET / ORAL		233 mg	Exact identifier — unii candidate 78 equally ranked IID candidates
edetate disodium	EDETATE DISODIUM	7FLD91C86K	EMULSION / OPHTHALMIC	0.3 %w/v		Exact identifier — unii candidate 77 equally ranked IID candidates
petrolatum	PETROLATUM	4T6H12BN9U	TABLET / ORAL	3.5 mg		Exact identifier — unii candidate 18 equally ranked IID candidates
polysorbate 80	POLYSORBATE 80	6OZP39ZG8H	TABLET, FILM COATED, EXTENDED RELEASE / ORAL	8 mg		Exact identifier — unii candidate 78 equally ranked IID candidates
glycerin	GLYCERIN	PDC6A3C0OX	INJECTION / INTRAVENOUS		33750 mg	Exact identifier — unii candidate 75 equally ranked IID candidates
edetate disodium	EDETATE DISODIUM	7FLD91C86K	SYSTEM / IONTOPHORESIS	0.1 mg		Exact identifier — unii candidate 77 equally ranked IID candidates
xanthan gum	XANTHAN GUM	TTV12P4NEE	CREAM / TOPICAL		46 mg	Exact identifier — unii candidate 29 equally ranked IID candidates
edetate disodium	EDETATE DISODIUM	7FLD91C86K	INJECTION / INTRABURSAL	0.01 %w/v		Exact identifier — unii candidate 77 equally ranked IID candidates
polysorbate 80	POLYSORBATE 80	6OZP39ZG8H	LOTION / TOPICAL	15 %w/w		Exact identifier — unii candidate 78 equally ranked IID candidates
edetate disodium	EDETATE DISODIUM	7FLD91C86K	INJECTION / INTRAVENOUS	10 %w/v		Exact identifier — unii candidate 77 equally ranked IID candidates
high density polyethylene	HIGH DENSITY POLYETHYLENE	UG00KM4WR7	CAPSULE, EXTENDED RELEASE / ORAL	4.53 mg		Exact identifier — unii candidate 18 equally ranked IID candidates
glycerin	GLYCERIN	PDC6A3C0OX	GEL / OPHTHALMIC	0.88 %w/w		Exact identifier — unii candidate 75 equally ranked IID candidates
glycerin	GLYCERIN	PDC6A3C0OX	SPRAY, METERED / NASAL		13 mg	Exact identifier — unii candidate 75 equally ranked IID candidates
glycerin	GLYCERIN	PDC6A3C0OX	SUSPENSION/ DROPS / ORAL		750 mg	Exact identifier — unii candidate 75 equally ranked IID candidates
high density polyethylene	HIGH DENSITY POLYETHYLENE	UG00KM4WR7	SUPPOSITORY / VAGINAL	NA		Exact identifier — unii candidate 18 equally ranked IID candidates
glycerin	GLYCERIN	PDC6A3C0OX	SUSPENSION/ DROPS / OPHTHALMIC	2.5 %w/v		Exact identifier — unii candidate 75 equally ranked IID candidates
polysorbate 80	POLYSORBATE 80	6OZP39ZG8H	INJECTION, SOLUTION, CONCENTRATE / INTRAVENOUS		4739 mg	Exact identifier — unii candidate 78 equally ranked IID candidates
tromethamine	TROMETHAMINE	023C2WHX2V	INJECTION, SOLUTION / INTRA-ARTERIAL		300 mg	Exact identifier — unii candidate 28 equally ranked IID candidates
polysorbate 80	POLYSORBATE 80	6OZP39ZG8H	TABLET, COATED / ORAL		18 mg	Exact identifier — unii candidate 78 equally ranked IID candidates
xanthan gum	XANTHAN GUM	TTV12P4NEE	FILM, SOLUBLE / ORAL		1 mg	Exact identifier — unii candidate 29 equally ranked IID candidates
polysorbate 80	POLYSORBATE 80	6OZP39ZG8H	SUPPOSITORY / VAGINAL	28 mg		Exact identifier — unii candidate 78 equally ranked IID candidates
glycerin	GLYCERIN	PDC6A3C0OX	AEROSOL / TOPICAL	3 %w/w		Exact identifier — unii candidate 75 equally ranked IID candidates
glycerin	GLYCERIN	PDC6A3C0OX	AEROSOL, FOAM / TOPICAL		21 mg	Exact identifier — unii candidate 75 equally ranked IID candidates
peg-100 stearate	PEG-100 MONOSTEARATE	YD01N1999R	CREAM / VAGINAL		100 mg	Exact identifier — unii candidate 3 equally ranked IID candidates
xanthan gum	XANTHAN GUM	TTV12P4NEE	TABLET, FILM COATED / ORAL	0.08 mg		Exact identifier — unii candidate 29 equally ranked IID candidates
glycerin	GLYCERIN	PDC6A3C0OX	PASTE, DENTIFRICE / DENTAL	18 %w/w		Exact identifier — unii candidate 75 equally ranked IID candidates
SHEA BUTTER	SHEA BUTTER	K49155WL9Y	LOTION / TOPICAL		2340 mg	Exact identifier — unii candidate
cetostearyl alcohol	CETOSTEARYL ALCOHOL	2DMT128M1S	TABLET, EXTENDED RELEASE / ORAL		800 mg	Exact identifier — unii candidate 9 equally ranked IID candidates
tromethamine	TROMETHAMINE	023C2WHX2V	GEL / TRANSDERMAL		10 mg	Exact identifier — unii candidate 28 equally ranked IID candidates
edetate disodium	EDETATE DISODIUM	7FLD91C86K	SPRAY / RESPIRATORY (INHALATION)	0.05 %w/w		Exact identifier — unii candidate 77 equally ranked IID candidates
edetate disodium	EDETATE DISODIUM	7FLD91C86K	POWDER, FOR SUSPENSION / ORAL		285 mg	Exact identifier — unii candidate 77 equally ranked IID candidates
glycerin	GLYCERIN	PDC6A3C0OX	SOLUTION / TOPICAL		1971 mg	Exact identifier — unii candidate 75 equally ranked IID candidates
polysorbate 80	POLYSORBATE 80	6OZP39ZG8H	TABLET / SUBLINGUAL	0.08 mg		Exact identifier — unii candidate 78 equally ranked IID candidates
xanthan gum	XANTHAN GUM	TTV12P4NEE	SUSPENSION / RECTAL		452 mg	Exact identifier — unii candidate 29 equally ranked IID candidates

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
0b042b50-ccb2-46a3-a595-3d9cb36f95d1			a0ebb2ae-8d3a-45a8-bfbd-dc5c988ff621	2021-07-19	Warnings	Exact identifier spl set id: a0ebb2ae-8d3a-45a8-bfbd-dc5c988ff621

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.