Safeguard Antibacterial Hand

Manufacturer: The Procter & Gamble Manufacturing Company
Effective date: 2025-03-17
Label type: HUMAN OTC DRUG LABEL
Version: 6
Source: full-release
Hydrated at: 2026-06-01 00:57:22

Label at a glance#

ProductSafeguard Antibacterial Hand

Active ingredientCHLOROXYLENOL

Label structure10 sections

Dosage and administration

Wet hands and forearms. Apply 5 milliliters (teaspoonful) or palmful to hands and forearms. Scrub thoroughly for 20 seconds and rinse.

Contacts and useful links#

PhoneLabel contact1-800-332-7787

PhoneLabel contact1-800-595-1375

Label contents#

Full prescribing information#

SPL UNCLASSIFIED SECTION

Drug Facts

Active Ingredient

OTC - ACTIVE INGREDIENT SECTION

Chloroxylenol 0.5%

Purpose

OTC - PURPOSE SECTION

Antibacterial

Use

INDICATIONS & USAGE SECTION

For handwashing to decrease bacteria on skin. Recommended for repeated use.

Warnings

WARNINGS SECTION

For external use only.

OTC - DO NOT USE SECTION

Do not use this product on infants under 6 months of age.

OTC - WHEN USING SECTION

When using this product avoid contact with eyes. If this happens, rinse thoroughly with water.

OTC - STOP USE SECTION

Stop use if irritation occurs.

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

Keep out of reach of children, except under adult supervision. If swallowed, get medical help or contact a Poison Control Center right away.

Directions

DOSAGE & ADMINISTRATION SECTION

Wet hands and forearms. Apply 5 milliliters (teaspoonful) or palmful to hands and forearms. Scrub thoroughly for 20 seconds and rinse.

Inactive ingredients

INACTIVE INGREDIENT SECTION

Water, sodium lauryl sulfate, sodium laureth sulfate, cocamide MEA, phenoxyethanol, glycol distearate, cocamidopropyl betaine, sodium sulfate, citric acid, fragrance, guar hydroxypropyltrimonium chloride, DMDM hydantoin, tetrasodium EDTA, yellow 5, red 4

Questions?

OTC - QUESTIONS SECTION

1-800-332-7787 (professional sizes)

1-800-595-1375 (personal size)

SPL UNCLASSIFIED SECTION

Distr. by PROCTER & GAMBLE, CINCINNATI, OH 45202.

PRINCIPAL DISPLAY PANEL - 3.78 L Bottle Label

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

Liquid Ready-to-Use

Safeguard^™ Antibacterial Hand Soap

Helps remove bacteria from skin

Chloroxylenol Antibacterial Hand Soap

3.78 L/1 GALLON

safeguard

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
362d7abb-94e6-4c60-9a58-266894157713	Product name	1	20231023

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDC	Effective	Action	Document	Indexing SPL	Related label
69423-053-37	2020-02-25	C162847	48780-1	9d75b9d0-7a83-f424-e053-dadaa90a57ce	Safeguard ™ Antibacterial Hand Soap
69423-053-80	2020-02-25	C162847	48780-1	9d75b9d0-7a83-f424-e053-dadaa90a57ce	Safeguard ™ Antibacterial Hand Soap
69423-053-37	2020-01-31	C162847	48780-1	9d75b9d0-7a83-f424-e053-dadaa90a57ce	Safeguard ™ Antibacterial Hand Soap
69423-053-80	2020-01-31	C162847	48780-1	9d75b9d0-7a83-f424-e053-dadaa90a57ce	Safeguard ™ Antibacterial Hand Soap

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
69423-053-30	Safeguard Antibacterial Hand	300 mL in 1 BOTTLE, PUMP	LIQUID	300	6
69423-053-37	Safeguard Antibacterial Hand	3780 mL in 1 BOTTLE, PUMP	LIQUID	3780	6
69423-053-80	Safeguard Antibacterial Hand	800 mL in 1 POUCH	LIQUID	800	6

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
69423-053	SAFEGUARD ANTIBACTERIAL HAND (CHLOROXYLENOL) LIQUID [THE PROCTER & GAMBLE MANUFACTURING COMPANY]	6	Current NDC, Legacy NDC, 3 package rows	20250321_a252f342-4019-4e0e-a588-d1b82df1065b.zip

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	SPL version
Chloroxylenol	ACTIVE INGREDIENT	0F32U78V2Q	1
Chloroxylenol	ACTIVE MOIETY	0F32U78V2Q	1
citric acid monohydrate	INACTIVE INGREDIENT	2968PHW8QP	1
cocamidopropyl betaine	INACTIVE INGREDIENT	5OCF3O11KX	1
DMDM hydantoin	INACTIVE INGREDIENT	BYR0546TOW	1
edetate sodium	INACTIVE INGREDIENT	MP1J8420LU	1
FD&C red no. 4	INACTIVE INGREDIENT	X3W0AM1JLX	1
FD&C yellow no. 5	INACTIVE INGREDIENT	I753WB2F1M	1
glycol distearate	INACTIVE INGREDIENT	13W7MDN21W	1
lauric diethanolamide	INACTIVE INGREDIENT	I29I2VHG38	1
sodium laureth-3 sulfate	INACTIVE INGREDIENT	BPV390UAP0	1
sodium lauryl sulfate	INACTIVE INGREDIENT	368GB5141J	1
sodium sulfate	INACTIVE INGREDIENT	0YPR65R21J	1
water	INACTIVE INGREDIENT	059QF0KO0R	1

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 16 matching rows.

Safeguard Antibacterial Hand
Chloroxylenol
PHENOXYETHANOL
TETRASODIUM EDTA
GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE
WATER
SODIUM LAURYL SULFATE
SODIUM LAURETH SULFATE
COCAMIDE MEA
GLYCOL DISTEARATE
COCAMIDOPROPYL BETAINE
SODIUM SULFATE
CITRIC ACID
DMDM HYDANTOIN
YELLOW 5
RED 4

NDC Codes#

Product NDC, Package NDC table
Product NDC	Package NDC
69423-053	69423-053-37, 69423-053-80, 69423-053-30

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 15 matching rows.

Name, UNII, Kind table
Name	UNII	Kind
PHENOXYETHANOL	HIE492ZZ3T	IACT
TETRASODIUM EDTA	MP1J8420LU	IACT
GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE	B16G315W7A	IACT
WATER	059QF0KO0R	IACT
SODIUM LAURYL SULFATE	368GB5141J	IACT
SODIUM LAURETH SULFATE	BPV390UAP0	IACT
COCAMIDE MEA	C80684146D	IACT
GLYCOL DISTEARATE	13W7MDN21W	IACT
COCAMIDOPROPYL BETAINE	5OCF3O11KX	IACT
SODIUM SULFATE	0YPR65R21J	IACT
CITRIC ACID	2968PHW8QP	IACT
DMDM HYDANTOIN	BYR0546TOW	IACT
YELLOW 5	I753WB2F1M	IACT
RED 4	X3W0AM1JLX	IACT
CHLOROXYLENOL	0F32U78V2Q	ACTIB

Source Document#

Source XML

Inactive ingredient matches#

Inactive Ingredient Database values describe FDA-listed use contexts. The match method and ambiguity count are shown because ingredient names, routes, and dosage forms are not always unique. Browse recovered IID releases and source provenance.

Inactive ingredient links page 1 of 4 · 184 matching rows.

DailyMed ingredient, IID ingredient, UNII table
DailyMed ingredient	IID ingredient	UNII	Dosage form / route	Potency	Maximum daily exposure	Match
citric acid monohydrate	CITRIC ACID MONOHYDRATE	2968PHW8QP	SYSTEM / TOPICAL	0.2 mg		Exact identifier — unii+route 68 equally ranked IID candidates
citric acid monohydrate	CITRIC ACID MONOHYDRATE	2968PHW8QP	SOLUTION / TOPICAL		17 mg	Exact identifier — unii+route 68 equally ranked IID candidates
lauric diethanolamide	LAURIC DIETHANOLAMIDE	I29I2VHG38	SUSPENSION / TOPICAL	0.48 %w/v		Exact identifier — unii+route 24 equally ranked IID candidates
sodium laureth-3 sulfate	SODIUM LAURETH-3 SULFATE	BPV390UAP0	SHAMPOO / TOPICAL		3192 mg	Exact identifier — unii+route 12 equally ranked IID candidates
FD&C yellow no. 5	FD&C YELLOW NO. 5	I753WB2F1M	SOLUTION / TOPICAL	0.06 %w/w		Exact identifier — unii+route 16 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	SPONGE / TOPICAL	5 %w/w		Exact identifier — unii+route 32 equally ranked IID candidates
lauric diethanolamide	LAURIC DIETHANOLAMIDE	I29I2VHG38	SUSPENSION / TOPICAL	0.48 %w/v		Exact identifier — unii+route 24 equally ranked IID candidates
sodium laureth-3 sulfate	SODIUM LAURETH-3 SULFATE	BPV390UAP0	SPRAY / TOPICAL	0.1 %w/w		Exact identifier — unii+route 12 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	SPRAY / TOPICAL		7 mg	Exact identifier — unii+route 32 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	SHAMPOO, SUSPENSION / TOPICAL	40 %w/v		Exact identifier — unii+route 32 equally ranked IID candidates
edetate sodium	EDETATE SODIUM	MP1J8420LU	LOTION / TOPICAL	0.17 %w/w		Exact identifier — unii+route 20 equally ranked IID candidates
FD&C yellow no. 5	FD&C YELLOW NO. 5	I753WB2F1M	SOLUTION / TOPICAL	0.06 %w/w		Exact identifier — unii+route 16 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	GEL / TOPICAL	0.05 %w/w		Exact identifier — unii+route 32 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	SHAMPOO / TOPICAL	65 %w/w		Exact identifier — unii+route 32 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	CREAM / TOPICAL		214 mg	Exact identifier — unii+route 32 equally ranked IID candidates
citric acid monohydrate	CITRIC ACID MONOHYDRATE	2968PHW8QP	EMULSION / TOPICAL	0.11 %w/w		Exact identifier — unii+route 68 equally ranked IID candidates
citric acid monohydrate	CITRIC ACID MONOHYDRATE	2968PHW8QP	OINTMENT / TOPICAL		1 mg	Exact identifier — unii+route 68 equally ranked IID candidates
citric acid monohydrate	CITRIC ACID MONOHYDRATE	2968PHW8QP	SOLUTION/ DROPS / TOPICAL	0.01 %w/v		Exact identifier — unii+route 68 equally ranked IID candidates
lauric diethanolamide	LAURIC DIETHANOLAMIDE	I29I2VHG38	SHAMPOO, SUSPENSION / TOPICAL	4 %w/v		Exact identifier — unii+route 24 equally ranked IID candidates
citric acid monohydrate	CITRIC ACID MONOHYDRATE	2968PHW8QP	SHAMPOO / TOPICAL		17 mg	Exact identifier — unii+route 68 equally ranked IID candidates
lauric diethanolamide	LAURIC DIETHANOLAMIDE	I29I2VHG38	SHAMPOO, SUSPENSION / TOPICAL	4 %w/v		Exact identifier — unii+route 24 equally ranked IID candidates
citric acid monohydrate	CITRIC ACID MONOHYDRATE	2968PHW8QP	SYSTEM / TOPICAL	0.2 mg		Exact identifier — unii+route 68 equally ranked IID candidates
citric acid monohydrate	CITRIC ACID MONOHYDRATE	2968PHW8QP	POWDER, FOR SOLUTION / TOPICAL	NA		Exact identifier — unii+route 68 equally ranked IID candidates
citric acid monohydrate	CITRIC ACID MONOHYDRATE	2968PHW8QP	LIQUID / INTRAVENOUS	0.2 %w/v		Exact identifier — unii+dosage form 68 equally ranked IID candidates
edetate sodium	EDETATE SODIUM	MP1J8420LU	SOLUTION / TOPICAL	0.3 %w/w		Exact identifier — unii+route 20 equally ranked IID candidates
sodium sulfate	SODIUM SULFATE	0YPR65R21J	SOAP / TOPICAL	0.05 %w/w		Exact identifier — unii+route 8 equally ranked IID candidates
sodium laureth-3 sulfate	SODIUM LAURETH-3 SULFATE	BPV390UAP0	SPRAY / TOPICAL	0.1 %w/w		Exact identifier — unii+route 12 equally ranked IID candidates
citric acid monohydrate	CITRIC ACID MONOHYDRATE	2968PHW8QP	OINTMENT / TOPICAL		1 mg	Exact identifier — unii+route 68 equally ranked IID candidates
FD&C yellow no. 5	FD&C YELLOW NO. 5	I753WB2F1M	POWDER / TOPICAL	NA		Exact identifier — unii+route 16 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	LOTION / TOPICAL		111 mg	Exact identifier — unii+route 32 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	GEL / TOPICAL	0.05 %w/w		Exact identifier — unii+route 32 equally ranked IID candidates
lauric diethanolamide	LAURIC DIETHANOLAMIDE	I29I2VHG38	SPONGE / TOPICAL	5 %w/w		Exact identifier — unii+route 24 equally ranked IID candidates
citric acid monohydrate	CITRIC ACID MONOHYDRATE	2968PHW8QP	LIQUID / RESPIRATORY (INHALATION)	0.13 %w/w		Exact identifier — unii+dosage form 68 equally ranked IID candidates
citric acid monohydrate	CITRIC ACID MONOHYDRATE	2968PHW8QP	LOTION / TOPICAL	0.85 %w/w		Exact identifier — unii+route 68 equally ranked IID candidates
lauric diethanolamide	LAURIC DIETHANOLAMIDE	I29I2VHG38	LOTION / TOPICAL	0.6 %w/v		Exact identifier — unii+route 24 equally ranked IID candidates
citric acid monohydrate	CITRIC ACID MONOHYDRATE	2968PHW8QP	SWAB / TOPICAL	0.05 %w/w		Exact identifier — unii+route 68 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	SHAMPOO, SUSPENSION / TOPICAL	40 %w/v		Exact identifier — unii+route 32 equally ranked IID candidates
citric acid monohydrate	CITRIC ACID MONOHYDRATE	2968PHW8QP	GEL / TOPICAL		1 mg	Exact identifier — unii+route 68 equally ranked IID candidates
citric acid monohydrate	CITRIC ACID MONOHYDRATE	2968PHW8QP	SOAP / TOPICAL	0.5 %w/w		Exact identifier — unii+route 68 equally ranked IID candidates
citric acid monohydrate	CITRIC ACID MONOHYDRATE	2968PHW8QP	CREAM / TOPICAL		4 mg	Exact identifier — unii+route 68 equally ranked IID candidates
citric acid monohydrate	CITRIC ACID MONOHYDRATE	2968PHW8QP	LIQUID / ORAL		114 mg	Exact identifier — unii+dosage form 68 equally ranked IID candidates
citric acid monohydrate	CITRIC ACID MONOHYDRATE	2968PHW8QP	OINTMENT / TOPICAL		1 mg	Exact identifier — unii+route 68 equally ranked IID candidates
citric acid monohydrate	CITRIC ACID MONOHYDRATE	2968PHW8QP	SOLUTION / TOPICAL		17 mg	Exact identifier — unii+route 68 equally ranked IID candidates
lauric diethanolamide	LAURIC DIETHANOLAMIDE	I29I2VHG38	SPONGE / TOPICAL	5 %w/w		Exact identifier — unii+route 24 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	GEL / TOPICAL	0.05 %w/w		Exact identifier — unii+route 32 equally ranked IID candidates
citric acid monohydrate	CITRIC ACID MONOHYDRATE	2968PHW8QP	LOTION / TOPICAL	0.85 %w/w		Exact identifier — unii+route 68 equally ranked IID candidates
lauric diethanolamide	LAURIC DIETHANOLAMIDE	I29I2VHG38	SHAMPOO, SUSPENSION / TOPICAL	4 %w/v		Exact identifier — unii+route 24 equally ranked IID candidates
FD&C yellow no. 5	FD&C YELLOW NO. 5	I753WB2F1M	SOLUTION / TOPICAL	0.06 %w/w		Exact identifier — unii+route 16 equally ranked IID candidates
FD&C yellow no. 5	FD&C YELLOW NO. 5	I753WB2F1M	LIQUID / ORAL	NA		Exact identifier — unii+dosage form 16 equally ranked IID candidates
edetate sodium	EDETATE SODIUM	MP1J8420LU	SPONGE / TOPICAL	0.14 %w/w		Exact identifier — unii+route 20 equally ranked IID candidates
citric acid monohydrate	CITRIC ACID MONOHYDRATE	2968PHW8QP	LIQUID / INTRAVENOUS	0.2 %w/v		Exact identifier — unii+dosage form 68 equally ranked IID candidates
sodium sulfate	SODIUM SULFATE	0YPR65R21J	SHAMPOO / TOPICAL	5 %w/w		Exact identifier — unii+route 8 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	CREAM / TOPICAL		214 mg	Exact identifier — unii+route 32 equally ranked IID candidates
citric acid monohydrate	CITRIC ACID MONOHYDRATE	2968PHW8QP	LIQUID / INTRAVENOUS	0.2 %w/v		Exact identifier — unii+dosage form 68 equally ranked IID candidates
FD&C yellow no. 5	FD&C YELLOW NO. 5	I753WB2F1M	LIQUID / ORAL	NA		Exact identifier — unii+dosage form 16 equally ranked IID candidates
lauric diethanolamide	LAURIC DIETHANOLAMIDE	I29I2VHG38	EMULSION / TOPICAL	15 %w/w		Exact identifier — unii+route 24 equally ranked IID candidates
sodium laureth-3 sulfate	SODIUM LAURETH-3 SULFATE	BPV390UAP0	CREAM / TOPICAL	NA		Exact identifier — unii+route 12 equally ranked IID candidates
lauric diethanolamide	LAURIC DIETHANOLAMIDE	I29I2VHG38	SHAMPOO / TOPICAL	20 %w/w		Exact identifier — unii+route 24 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	GEL / TOPICAL	0.05 %w/w		Exact identifier — unii+route 32 equally ranked IID candidates
citric acid monohydrate	CITRIC ACID MONOHYDRATE	2968PHW8QP	AEROSOL, FOAM / TOPICAL		1 mg	Exact identifier — unii+route 68 equally ranked IID candidates

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Safeguard Antibacterial Hand	CHLOROXYLENOL	The Procter & Gamble Manufacturing Company	a252f342-4019-4e0e-a588-d1b82df1065b	2025-03-17	Warnings	Exact identifier ndc (package): 69423-053-30 ndc (package): 69423-053-80 ndc (package): 69423-053-37 ndc (product): 69423-053 ndc11 (package): 69423005380 ndc11 (package): 69423005337 ndc11 (package): 69423005330 spl id: 308c505e-e1db-01e0-e063-6394a90a6be4 spl set id: a252f342-4019-4e0e-a588-d1b82df1065b

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.