Indications and uses
temporarily relieves these symptoms due to a cold: minor aches and pains minor sore throat pain headache nasal and sinus congestion cough due to minor throat and bronchial irritation temporarily reduces fever
Multi Symptom Severe Cold and Nighttime Severe Cold and Cough
- Manufacturer
- WAL-MART STORES INC
- Effective date
- 2025-12-02
- Label type
- HUMAN OTC DRUG LABEL
- Version
- 8
- Source
- full-release
- Hydrated at
- 2026-06-01 01:19:08
Label at a glance#
ProductMulti Symptom Severe Cold and Nighttime Severe Cold and Cough
Active ingredientACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE HYDROCHLORIDE, DIPHENHYDRAMINE HYDROCHLORIDE
Label structure25 sections
Dosage and administration
do not use more than directed take every 4 hours, while symptoms persist .do not take more than 6 packets in 24 hours unless directed by a doctor Age Dose Adults and children 12 years of age One packet Children under 12 years of age Do not use dissolve contents of one packet into 8 oz. hot water: sip while hot. Consume entire drink within 10 - 15 minutes. if using a microwave, add contents of one packet to 8 oz. o...
Storage and handling
each packet contains: potassium 6 mg store at room temperature. Protect from excessive heat and moisture.
Contacts and useful links#
Label contents#
Full prescribing information#
Active ingredients (in each packet) – Multi Symptom Severe Cold
Acetaminophen 500 mg
Dextromethorphan hydrobromide 20 mg
Phenylephrine hydrochloride 10 mg
Active ingredients (in each packet) - Nighttime Severe Cold and Cough
Acetaminophen 650 mg
Diphenhydramine hydrochloride 25 mg
Phenylephrine hydrochloride 10 mg
Purpose - Multi Symptom Severe Cold
Pain reliever/fever reducer
Cough Suppressant
Nasal Decongestant
Purpose - Nighttime Severe Cold and Cough
Pain reliever/fever reducer
Antihistamine/Cough suppressant
Nasal decongestant
Uses - Multi Symptom Severe Cold
- temporarily relieves these symptoms due to a cold:
- minor aches and pains
- minor sore throat pain
- headache
- nasal and sinus congestion
- cough due to minor throat and bronchial irritation
- temporarily reduces fever
Uses - Nighttime Severe Cold and Cough
- temporarily relieves these symptoms due to a cold:
- minor aches and pains
- minor sore throat pain
- headache
- nasal and sinus congestion
- runny nose
- sneezing
- itchy nose or throat
- itchy, watery eyes due to hay fever
- cough due to minor throat and bronchial irritation
- temporarily reduces fever
Warnings – Multi Symptom Severe Cold /Nighttime Severe Cold and Cough
Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take
- more than 4,000 mg of acetaminophen in 24 hours
- with other drugs containing acetaminophen
- 3 or more alcoholic drinks every day while using this product
Allergy alert:Acetaminophen may cause severe skin reactions. Symptoms may include:
- skin reddening
- blisters
- rash
If a skin reaction occurs, stop use and seek medical help right away
Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.
Do not use - Multi Symptom Severe Cold
- in a child under 12 years of age
- if you are allergic to acetaminophen
- with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or a pharmacist.
- if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
Do not use - Nighttime Severe Cold and Cough
- in a child under 12 years of age
- if you are allergic to acetaminophen
- with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or a pharmacist.
- with any other product containing diphenhydramine, even one used on skin
- if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
Ask a doctor before use if you have - Multi Symptom Severe Cold
- liver disease
- heart disease
- high blood pressure
- thyroid disease
- diabetes
- trouble urinating due to an enlarged prostate gland
- cough that occurs with too much phlegm (mucus)
- cough that lasts or is chronic such as occurs with smoking, asthma, or emphysema
Ask a doctor before use if you have - Nighttime Severe Cold and Cough
- liver disease
- heart disease
- high blood pressure
- thyroid disease
- diabetes
- glaucoma
- trouble urinating due to an enlarged prostate gland
- a breathing problem such as emphysema or chronic bronchitis
- cough that occurs with too much phlegm (mucus)
- cough that lasts or is chronic such as occurs with smoking, asthma, or emphysema
Ask a doctor or pharmacist before use if you are - Multi Symptom Severe Cold
taking the blood thinning drug warfarin
Ask a doctor or pharmacist before use if you are - Nighttime Severe Cold and Cough
- taking sedatives or tranquilizers
- taking the blood thinning drug warfarin
When using this product - Multi Symptom Severe Cold
do not exceed recommended dosage
When using this product - Nighttime Severe Cold and Cough
- do not exceed recommended dosage
- avoid alcoholic drinks
- marked drowsiness may occur
- alcohol, sedatives, and tranquilizers may increase drowsiness
- be careful when driving a motor vehicle or operating machinery
- excitability may occur, especially in children
Stop use and ask a doctor if – Multi Symptom Severe Cold /Nighttime Severe Cold and Cough
- nervousness, dizziness, or sleeplessness occurs
- fever gets worse or lasts more than 3 days
- redness or swelling is present
- new symptoms occur
- pain, cough or nasal congestion gets worse or lasts more than 7 days
- cough comes back or occurs with fever, rash or headache that lasts. These could be signs of a serious condition.
If pregnant or breast-feeding,
ask a health professional before use.
Keep out of reach of children.
In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
Directions – Multi Symptom Severe Cold
- do not use more than directed
- take every 4 hours, while symptoms persist .do not take more than 6 packets in 24 hours unless directed by a doctor
Age | Dose |
Adults and children 12 years of age | One packet |
Children under 12 years of age | Do not use |
- dissolve contents of one packet into 8 oz. hot water: sip while hot. Consume entire drink within 10 - 15 minutes.
- if using a microwave, add contents of one packet to 8 oz. of cool water: stir briskly before and after heating, Do not overheat
Directions Nighttime Severe Cold and Cough
- do not use more than directed
- take every 4 hours while symptoms persist, not to exceed 5 packets in 24 hours unless directed by a doctor
Age | Dose |
Adults and Children 12 years of age and over | One packet |
Children under 12 years of age | do not use |
- dissolve contents of one packet into 8 oz. hot water: sip while hot. Consume entire drink within 10 - 15 minutes.
- if using a microwave, add contents of one packet to 8 oz. of cool water: stir briskly before and after heating, Do not overheat.
Other information - Multi Symptom Severe Cold
- each packet contains: potassium 6 mg
- store at room temperature. Protect from excessive heat and moisture.
Other information - Nighttime Severe Cold and Cough
- each packet contains: potassium 6 mg
- store at room temperature. Protect from excessive heat and moisture
Inactive ingredients - Multi Symptom Severe Cold
citric acid, caramel, flavors, maltodextrin, potassium chloride, silica, sucralose, sucrose
Inactive ingredients - Nighttime Severe Cold and Cough
citric acid, F D & C yellow #6 , flavors, maltodextrin, potassium chloride, silica ,sucralose, sucrose,
Questions or comments?
1-866-467-2748
Package/Label Principal Display Panel
NDC# 49035-948-12
DAYTIME & NIGHTTIME RELIEF VALUE PACK
Compare to active ingredients in Theraflu® Multi Symptom Severe Cold* and Nighttime Severe Cold & Cough *
MULTI- SYMPTOM
SEVERE COLD
ACETAMINOPHEN /PAIN RELIEVER/ FEVER REDUCER
DEXTROMETHORPHAN HBr / COUGH SUPPRESSANT
PHENYLEPHRINE HCl / NASAL DECONGESTANT
DYE FREE
ASPARTAME FREE
SODIUM FREE
Relieves
- Nasal congestion
- Sore throat pain
- Cough
- Headache
- Body ache
- Fever
GREEN TEA & HONEY LEMON FLAVORS
INFUSED WITH MENTHOL AND GREEN TEA FLAVOR
Naturally and Artificially Flavored
- 6 MULTI-SYMPTOM PACKETS
NIGHTTIME SEVERE & COLD & COUGH
ACETAMINOPHEN/ PAIN RELIEVER/ FEVER REDUCER
DIPHENHYDRAMINE HCl / ANTIHISTAMINE/ COUGH SUPPRESSANT
PHENYLEPHRINE HCl / NASAL DECONGESTANT
ASPARTAME FREE
SODIUM FREE
Relieves
- Nasal congestion
- Sore throat pain
- Cough
- Headache
- Body ache & fever
- Runny nose
- Sneezing
HONEY LEMON FLAVOR INFUSED WITH CHAMOMILE &WHITE TEA FLAVORS
6 NIGHTTIME PACKETS
12 TOTAL PACKETS
READ ALL WARNINGS AND DIRECTIONS ON CARTON BEFORE USE .KEEP CARTON FOR REFERENCE, DO NOT DISCARD. |
DO NOT TAKE BOTH PRODUCTS AT THE SAME TIME OR TAKE MORE THAN 5 DOSES IN TOTAL IN ANY 24 –HOUR PERIOD. |
DO NOT TAKE A DOSE OF THE NIGHTTIME PRODUCT SOONER THAN 4 HOURS AFTER THE LAST DOSE OF DAYTIME PRODUCT UNLESS DIRECTED BY DOCTOR. |
*These Products are not manufactured or distributed by GSK Consumer Healthcare, distributor of Theraflu ®Multi-Symptom Severe Cold & Theraflu ®Nighttime Severe Cold & Cough.
Distributed By:
Wal-Mart Stores, Inc. Bentoville, AR 72716
© Wal-Mart Stores, Inc.
*This product is not manufactured or distributed by Novartis Consumer Health Inc., Owner of the registered trademark Gas-X®.
TAMPER EVIDENT INNER UNIT: DO NOT USE IF SEALED PACKET IS TORN OR BROKEN |
DailyMed RxNorm Mappings#
| RxCUI | RxNorm string | TTY | SPL version |
|---|---|---|---|
| 2640034 | {1 (acetaminophen 500 MG / dextromethorphan hydrobromide 20 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution) / 1 (acetaminophen 650 MG / diphenhydramine hydrochloride 25 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution) } Pack | GPCK | 8 |
| 2640034 | 1 daytime (acetaminophen 500 MG / dextromethorphan HBr 20 MG / phenylephrine HCl 10 MG Granules for Oral Solution) / 1 nighttime (acetaminophen 650 MG / diphenhydrAMINE HCl 25 MG / phenylephrine HCl 10 MG Granules for Oral Solution) Pack | PSN | 8 |
| 1189316 | acetaminophen 500 MG / dextromethorphan HBr 20 MG / phenylephrine HCl 10 MG Granules for Oral Solution | PSN | 8 |
| 1659960 | acetaminophen 650 MG / diphenhydrAMINE HCl 25 MG / phenylephrine HCl 10 MG Granules for Oral Solution | PSN | 8 |
| 1189316 | acetaminophen 500 MG / dextromethorphan hydrobromide 20 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution | SCD | 8 |
| 1659960 | acetaminophen 650 MG / diphenhydramine hydrochloride 25 MG / phenylephrine hydrochloride 10 MG Granules for Oral Solution | SCD | 8 |
| 2640034 | 1 daytime (acetaminophen 500 MG / dextromethorphan HBr 20 MG / phenylephrine HCl 10 MG Granules for Oral Solution) / 1 nighttime (acetaminophen 650 MG / diphenhydramine HCl 25 MG / phenylephrine HCl 10 MG Granules for Oral Solution) Pack | SY | 8 |
| 1189316 | acetaminophen 500 MG / dextromethorphan HBr 20 MG / phenylephrine HCl 10 MG Packet for Oral Solution | SY | 8 |
| 1189316 | acetaminophen 500 MG / dextromethorphan hydrobromide 20 MG / phenylephrine hydrochloride 10 MG Powder for Oral Solution | SY | 8 |
| 1659960 | acetaminophen 650 MG / diphenhydramine HCl 25 MG / phenylephrine HCl 10 MG Packet for Oral Solution | SY | 8 |
| 1659960 | acetaminophen 650 MG / diphenhydramine hydrochloride 25 MG / phenylephrine hydrochloride 10 MG Powder for Oral Solution | SY | 8 |
| 1189316 | APAP 500 MG / Dextromethorphan Hydrobromide 20 MG / Phenylephrine Hydrochloride 10 MG Granules for Oral Solution | SY | 8 |
| 1659960 | APAP 650 MG / Diphenhydramine Hydrochloride 25 MG / Phenylephrine Hydrochloride 10 MG Granules for Oral Solution | SY | 8 |
DailyMed Pharmacologic Classes#
| Class | Version | Type | Effective |
|---|---|---|---|
| DEXTROMETHORPHAN Pharmacologic Class Indexing | 2 | Indexing - Pharmacologic Class | 20180813 |
| DIPHENHYDRAMINE Pharmacologic Class Indexing | 3 | Indexing - Pharmacologic Class | 20180813 |
| PHENYLEPHRINE Pharmacologic Class Indexing | 2 | Indexing - Pharmacologic Class | 20180813 |
DailyMed Product Concepts#
DailyMed Package Descriptions#
| Package NDC | Product | Description | Form | Quantity | Strength | SPL version |
|---|---|---|---|---|---|---|
| 49035-948-12 | Multi Symptom Severe Cold and Nighttime Severe Cold and Cough | 1 in 1 CARTON | KIT | 1 | 8 | |
| 79903-541-01 | Multi Symptom Severe Cold and Nighttime Severe Cold and Cough | 6 in 1 CARTON | POWDER, FOR SOLUTION | 10 mg | 8 | |
| 79903-541-01 | Multi Symptom Severe Cold and Nighttime Severe Cold and Cough | 1 in 1 PACKET | POWDER, FOR SOLUTION | 6 | 500 mg | 8 |
| 79903-547-01 | Multi Symptom Severe Cold and Nighttime Severe Cold and Cough | 6 in 1 CARTON | POWDER, FOR SOLUTION | 10 mg | 8 | |
| 79903-547-01 | Multi Symptom Severe Cold and Nighttime Severe Cold and Cough | 1 in 1 PACKET | POWDER, FOR SOLUTION | 6 | 10 mg | 8 |
Products#
Every source-derived product name is available through these pages.
- Multi Symptom Severe Cold and Nighttime Severe Cold and Cough
- Acetaminophen, Dextromethorphan HBr, Diphenhydramine HCl, Phenylephrine HCl
- Multi Symptom Severe Cold MULTI SYMPTOM SEVERE COLD
- ACETAMINOPHEN, DEXTROMETHORPHAN HBr, PHENYLEPHRINE HCl
- ANHYDROUS CITRIC ACID
- CARAMEL
- MALTODEXTRIN
- POTASSIUM CHLORIDE
- SILICON DIOXIDE
- SUCRALOSE
- SUCROSE
- ACETAMINOPHEN
- DEXTROMETHORPHAN HYDROBROMIDE
- DEXTROMETHORPHAN
- PHENYLEPHRINE HYDROCHLORIDE
- PHENYLEPHRINE
- Nighttime Severe Cold and Cough NIGHTTIME SEVERE COLD AND COUGH
- ACETAMINOPHEN, DIPHENHYDRAMINE HCl, PHENYLEPHRINE HCl
- FD&C YELLOW NO. 6
- DIPHENHYDRAMINE HYDROCHLORIDE
- DIPHENHYDRAMINE
NDC Codes#
| Product NDC | Package NDC |
|---|---|
| 49035-948 | 49035-948-12 |
| 79903-541 | 79903-541-01 |
| 79903-547 | 79903-547-01 |
Ingredients#
Every source-derived ingredient row is available through these pages.
Source Document#
openFDA label cross-check#
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| Multi Symptom Severe Cold and Nighttime Severe Cold and Cough | ACETAMINOPHEN, DEXTROMETHORPHAN HBR, DIPHENHYDRAMINE HCL, PHENYLEPHRINE HCL | WAL-MART STORES INC | a2a7e568-bff8-4818-a31d-7c2efa1859c3 | 2025-12-02 | Warnings | 79903-547-01 79903-541-01 49035-948-12 49035-948 79903054701 79903054101 49035094812 44f52e6c-e3b6-1574-e063-6294a90a3be7 a2a7e568-bff8-4818-a31d-7c2efa1859c3 |
Reported adverse events (FAERS/openFDA)#
Adverse event summaries are temporarily unavailable. Other product information remains available.