Soothe

Manufacturer: Walgreens
Effective date: 2024-07-25
Label type: HUMAN OTC DRUG LABEL
Version: 6
Source: full-release
Hydrated at: 2026-06-01 00:16:02

Label at a glance#

ProductSoothe

Active ingredientBISMUTH SUBSALICYLATE

Label structure10 sections

Indications and uses

relieves travelers' diarrhea diarrhea upset stomach due to overindulgence in food and drink, including: heartburn indigestion nausea gas fullness belching

Dosage and administration

mL = milliliter shake well before using measure only with dosing cup provided. Do not use any other dosing device. keep dosing cup with product adults and children 12 years and over: 30 mL (1 dose) every 1/2 to 1 hour as needed do not exceed 8 doses (240 mL) in 24 hours use until diarrhea stops but not more than 2 days children under 12 years of age: ask a doctor drink plenty of clear fluids to help prevent dehydr...

Storage and handling

each 30 mL contains : sodium 6 mg each 30 mL contains : salicylate 243 mg low sodium keep tightly closed protect from freezing avoid excessive heat (over 104ºF or 40ºC)

Contacts and useful links#

PhonePoison Help1-800-222-1222

PhoneLabel contact1-877-753-3935

Label contents#

Full prescribing information#

Active ingredient (in each 30 mL)

OTC - ACTIVE INGREDIENT SECTION

Bismuth subsalicylate 525 mg

Purpose

OTC - PURPOSE SECTION

Upset stomach reliever/Antidiarrheal

Uses

INDICATIONS & USAGE SECTION

relieves

travelers' diarrhea
diarrhea
upset stomach due to overindulgence in food and drink, including:
- heartburn
- indigestion
- nausea
- gas
- fullness
- belching

Warnings

WARNINGS SECTION

Reye's syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye's syndrome, a rare but serious illness.

Allergy alert: Contains salicylate. Do not take if you are

allergic to salicylates (including aspirin)
taking other salicylate products

Do not use

OTC - DO NOT USE SECTION

if you have

an ulcer
a bleeding problem
bloody or black stool

Ask a doctor before use if you have

OTC - ASK DOCTOR SECTION

fever
mucus in the stool

Ask a doctor or pharmacist before use if you are

OTC - ASK DOCTOR/PHARMACIST SECTION

taking any drug for

diabetes
gout
arthritis
anticoagulation (thinning the blood)

When using this product

OTC - WHEN USING SECTION

a temporary, but harmless, darkening of the stool and/or tongue may occur.

Stop use and ask a doctor if

OTC - STOP USE SECTION

symptoms get worse or last more than 2 days
ringing in the ears or loss of hearing occurs
diarrhea lasts more than 2 days

If pregnant or breast-feeding,

OTC - PREGNANCY OR BREAST FEEDING SECTION

ask a health professional before use.

Keep out of reach of childen.

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

In case of overdose, get medical help or contact a Posion Control Center right away. (1-800-222-1222)

Directions

DOSAGE & ADMINISTRATION SECTION

mL = milliliter
shake well before using
measure only with dosing cup provided. Do not use any other dosing device.
keep dosing cup with product
adults and children 12 years and over:
- 30 mL (1 dose) every 1/2 to 1 hour as needed
do not exceed 8 doses (240 mL) in 24 hours
use until diarrhea stops but not more than 2 days
children under 12 years of age: ask a doctor
drink plenty of clear fluids to help prevent dehydration caused by diarrhea

Other information

STORAGE AND HANDLING SECTION

each 30 mL contains: sodium 6 mg
each 30 mL contains: salicylate 243 mg
low sodium
keep tightly closed
protect from freezing
avoid excessive heat (over 104ºF or 40ºC)

Inactive ingredients

INACTIVE INGREDIENT SECTION

benzoic acid, D&C red #22, D&C red #28, flavor, magnesium aluminum silicate, methylcellulose, purified water, saccharin sodium, salicylic acid, sodium salicylate, sorbic acid

Questions or comments?

OTC - QUESTIONS SECTION

Call 1-877-753-3935 Monday-Friday 9AM-5PM EST

Principal Display Panel

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

Compare to Pepto-Bismol® active ingredient††

Soothe®

BISMUTH SUBSALICYLATE 525mg /

UPSET STOMACH RELIEVER /

ANTIDIARRHEAL

SUGAR FREE ALCOHOL FREE

Provides protective coating action to relieves heartburn, indigestion, nausea, upset stomach & diarrhea

FL OZ (mL)

≠≠This product is not manufactured or distributed by Procter & Gamble Company, Pepto-Bismol® is a registered trademark of The Protecter & Gamble Company.

TAMPER EVIDENT; DO NOT USE IF PRINTED SAFETY SEAL AROUND DOSAGE CUP OR UNDER CAP IS BROKEN OR MISSING.

DISTRIBUTED BY: WALGREEN CO.

200 WILMOT RD, DEERFIELD, IL 60015

walgreens.com

Package Label

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	SPL version
308762	bismuth subsalicylate 525 MG in 30 mL Oral Suspension	PSN	6
308762	bismuth subsalicylate 17.5 MG/ML Oral Suspension	SCD	6
308762	bismuth subsalicylate 1.75 % Oral Suspension	SY	6
308762	bismuth subsalicylate 262 MG per 15 ML Oral Suspension	SY	6
308762	bismuth subsalicylate 524 MG per 30 ML Oral Suspension	SY	6
308762	bismuth subsalicylate 525 MG per 30 ML Oral Suspension	SY	6

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
0be8e4ae-4d57-49f3-b3a9-e4728b4e8d15	Product name	1	20240313
c6f86816-7da6-43ea-8c25-ac9758311cc5	Product name	1	20220118
dea2eded-d1e7-46bb-9a3d-f8dc20de6277	Product name	1	20190408
252e11b6-1a9a-4283-a242-df2c129c496d	Product name	3	20170717

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
0363-0073-08	Soothe	237 mL in 1 BOTTLE, PLASTIC	LIQUID	237		6
0363-0073-16	Soothe	473 mL in 1 BOTTLE, PLASTIC	LIQUID	473		6

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
0363-0073	SOOTHE (BISMUTH SUBSALICYLATE) LIQUID [WALGREENS]	6	Current NDC, Legacy NDC, 2 package rows	20240726_a2b2b0ce-034e-4857-bfca-0087bb31878e.zip

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
0363-0073-08	ML - Milliliter	0363-0073	d3e745d2-731b-47cb-9842-0875d425495b	1	2022-06-06
0363-0073-16	ML - Milliliter	0363-0073	282791b9-15f8-4fb7-b333-35d74b923da2	1	2022-06-06

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	SPL version
BISMUTH SUBSALICYLATE	ACTIVE INGREDIENT	62TEY51RR1	2
SALICYLIC ACID	ACTIVE MOIETY	O414PZ4LPZ	2
BENZOIC ACID	INACTIVE INGREDIENT	8SKN0B0MIM	2
D&C RED NO. 22	INACTIVE INGREDIENT	1678RKX8RT	2
D&C RED NO. 28	INACTIVE INGREDIENT	767IP0Y5NH	2
MAGNESIUM ALUMINUM SILICATE	INACTIVE INGREDIENT	6M3P64V0NC	2
METHYLCELLULOSE (1500 MPA.S)	INACTIVE INGREDIENT	P0NTE48364	2
SACCHARIN SODIUM	INACTIVE INGREDIENT	SB8ZUX40TY	2
SALICYLIC ACID	INACTIVE INGREDIENT	O414PZ4LPZ	2
SODIUM SALICYLATE	INACTIVE INGREDIENT	WIQ1H85SYP	2
SORBIC ACID	INACTIVE INGREDIENT	X045WJ989B	2
WATER	INACTIVE INGREDIENT	059QF0KO0R	2

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 13 matching rows.

Soothe
Bismuth subsalicylate
BISMUTH CATION
SALICYLIC ACID
BENZOIC ACID
D&C RED NO. 22
D&C RED NO. 28
MAGNESIUM ALUMINUM SILICATE
WATER
SACCHARIN SODIUM
SODIUM SALICYLATE
SORBIC ACID
METHYLCELLULOSE (1500 CPS)

NDC Codes#

Product NDC, Package NDC table
Product NDC	Package NDC
0363-0073	0363-0073-08, 0363-0073-16

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 11 matching rows.

Name, UNII, Kind table
Name	UNII	Kind
BISMUTH SUBSALICYLATE	62TEY51RR1	ACTIB
BENZOIC ACID	8SKN0B0MIM	IACT
D&C RED NO. 22	1678RKX8RT	IACT
D&C RED NO. 28	767IP0Y5NH	IACT
MAGNESIUM ALUMINUM SILICATE	6M3P64V0NC	IACT
WATER	059QF0KO0R	IACT
SACCHARIN SODIUM	SB8ZUX40TY	IACT
SALICYLIC ACID	O414PZ4LPZ	IACT
SODIUM SALICYLATE	WIQ1H85SYP	IACT
SORBIC ACID	X045WJ989B	IACT
METHYLCELLULOSE (1500 CPS)	P0NTE48364	IACT

Source Document#

Source XML · Source PDF

Inactive ingredient matches#

Inactive Ingredient Database values describe FDA-listed use contexts. The match method and ambiguity count are shown because ingredient names, routes, and dosage forms are not always unique. Browse recovered IID releases and source provenance.

Inactive ingredient links page 1 of 2 · 84 matching rows.

DailyMed ingredient, IID ingredient, UNII table
DailyMed ingredient	IID ingredient	UNII	Dosage form / route	Potency	Maximum daily exposure	Match
D&C RED NO. 28	D&C RED NO. 28	767IP0Y5NH	SUSPENSION / ORAL	2.5 mg/5ml		Exact identifier — unii+route 27 equally ranked IID candidates
SORBIC ACID	SORBIC ACID	X045WJ989B	TABLET, COATED / ORAL		1 mg	Exact identifier — unii+route 30 equally ranked IID candidates
SORBIC ACID	SORBIC ACID	X045WJ989B	TABLET / ORAL		10 mg	Exact identifier — unii+route 30 equally ranked IID candidates
SORBIC ACID	SORBIC ACID	X045WJ989B	CONCENTRATE / ORAL		1 mg	Exact identifier — unii+route 30 equally ranked IID candidates
SORBIC ACID	SORBIC ACID	X045WJ989B	TABLET, FILM COATED / ORAL		5 mg	Exact identifier — unii+route 30 equally ranked IID candidates
SORBIC ACID	SORBIC ACID	X045WJ989B	TABLET, COATED / ORAL		1 mg	Exact identifier — unii+route 30 equally ranked IID candidates
D&C RED NO. 22	D&C RED NO. 22	1678RKX8RT	TABLET, COATED / ORAL	NA		Exact identifier — unii+route 15 equally ranked IID candidates
SACCHARIN SODIUM	SACCHARIN SODIUM	SB8ZUX40TY	LIQUID / ORAL		3 mg	Exact identifier — unii+route+dosage form 3 equally ranked IID candidates
SORBIC ACID	SORBIC ACID	X045WJ989B	TABLET, CHEWABLE / ORAL	NA		Exact identifier — unii+route 30 equally ranked IID candidates
D&C RED NO. 22	D&C RED NO. 22	1678RKX8RT	CAPSULE, EXTENDED RELEASE / ORAL	NA		Exact identifier — unii+route 15 equally ranked IID candidates
D&C RED NO. 28	D&C RED NO. 28	767IP0Y5NH	CAPSULE, COATED PELLETS / ORAL	NA		Exact identifier — unii+route 27 equally ranked IID candidates
D&C RED NO. 28	D&C RED NO. 28	767IP0Y5NH	CAPSULE, COATED, EXTENDED RELEASE / ORAL	NA		Exact identifier — unii+route 27 equally ranked IID candidates
SORBIC ACID	SORBIC ACID	X045WJ989B	CONCENTRATE / ORAL		1 mg	Exact identifier — unii+route 30 equally ranked IID candidates
METHYLCELLULOSE (1500 MPA.S)	METHYLCELLULOSE (1500 MPA.S)	P0NTE48364	TABLET / ORAL		319 mg	Exact identifier — unii+route 3 equally ranked IID candidates
METHYLCELLULOSE (1500 MPA.S)	METHYLCELLULOSE (1500 MPA.S)	P0NTE48364	TABLET / ORAL		319 mg	Exact identifier — unii+route 3 equally ranked IID candidates
D&C RED NO. 22	D&C RED NO. 22	1678RKX8RT	TABLET, DELAYED RELEASE / ORAL	0.38 mg		Exact identifier — unii+route 15 equally ranked IID candidates
D&C RED NO. 28	D&C RED NO. 28	767IP0Y5NH	CAPSULE / ORAL		1 mg	Exact identifier — unii+route 27 equally ranked IID candidates
D&C RED NO. 28	D&C RED NO. 28	767IP0Y5NH	POWDER, FOR SOLUTION / ORAL		3 mg	Exact identifier — unii+route 27 equally ranked IID candidates
SORBIC ACID	SORBIC ACID	X045WJ989B	TABLET, CHEWABLE / ORAL	NA		Exact identifier — unii+route 30 equally ranked IID candidates
SORBIC ACID	SORBIC ACID	X045WJ989B	TABLET / ORAL		10 mg	Exact identifier — unii+route 30 equally ranked IID candidates
D&C RED NO. 28	D&C RED NO. 28	767IP0Y5NH	CAPSULE, DELAYED RELEASE / ORAL		1 mg	Exact identifier — unii+route 27 equally ranked IID candidates
D&C RED NO. 22	D&C RED NO. 22	1678RKX8RT	CAPSULE, EXTENDED RELEASE / ORAL	NA		Exact identifier — unii+route 15 equally ranked IID candidates
D&C RED NO. 22	D&C RED NO. 22	1678RKX8RT	CAPSULE / ORAL	0.02 mg		Exact identifier — unii+route 15 equally ranked IID candidates
D&C RED NO. 22	D&C RED NO. 22	1678RKX8RT	TABLET, COATED / ORAL	NA		Exact identifier — unii+route 15 equally ranked IID candidates
SORBIC ACID	SORBIC ACID	X045WJ989B	TABLET, COATED / ORAL		1 mg	Exact identifier — unii+route 30 equally ranked IID candidates
D&C RED NO. 28	D&C RED NO. 28	767IP0Y5NH	POWDER, FOR SUSPENSION / ORAL	0.7 mg/5ml		Exact identifier — unii+route 27 equally ranked IID candidates
D&C RED NO. 28	D&C RED NO. 28	767IP0Y5NH	CAPSULE, EXTENDED RELEASE / ORAL	0.2 mg		Exact identifier — unii+route 27 equally ranked IID candidates
D&C RED NO. 28	D&C RED NO. 28	767IP0Y5NH	TABLET / ORAL	NA		Exact identifier — unii+route 27 equally ranked IID candidates
BENZOIC ACID	BENZOIC ACID	8SKN0B0MIM	LIQUID / ORAL	2 mg/1ml		Exact identifier — unii+route+dosage form 3 equally ranked IID candidates
D&C RED NO. 28	D&C RED NO. 28	767IP0Y5NH	SUSPENSION / ORAL	2.5 mg/5ml		Exact identifier — unii+route 27 equally ranked IID candidates
MAGNESIUM ALUMINUM SILICATE	MAGNESIUM ALUMINUM SILICATE	6M3P64V0NC	LIQUID / ORAL	82 mg/5ml		Exact identifier — unii+route+dosage form 3 equally ranked IID candidates
SORBIC ACID	SORBIC ACID	X045WJ989B	SYRUP / ORAL		80 mg	Exact identifier — unii+route 30 equally ranked IID candidates
SORBIC ACID	SORBIC ACID	X045WJ989B	TABLET / ORAL		10 mg	Exact identifier — unii+route 30 equally ranked IID candidates
D&C RED NO. 28	D&C RED NO. 28	767IP0Y5NH	POWDER, FOR SOLUTION / ORAL		3 mg	Exact identifier — unii+route 27 equally ranked IID candidates
SORBIC ACID	SORBIC ACID	X045WJ989B	CONCENTRATE / ORAL		1 mg	Exact identifier — unii+route 30 equally ranked IID candidates
D&C RED NO. 28	D&C RED NO. 28	767IP0Y5NH	CAPSULE, COATED, EXTENDED RELEASE / ORAL	NA		Exact identifier — unii+route 27 equally ranked IID candidates
SACCHARIN SODIUM	SACCHARIN SODIUM	SB8ZUX40TY	LIQUID / ORAL		3 mg	Exact identifier — unii+route+dosage form 3 equally ranked IID candidates
D&C RED NO. 28	D&C RED NO. 28	767IP0Y5NH	POWDER, FOR SUSPENSION / ORAL	0.7 mg/5ml		Exact identifier — unii+route 27 equally ranked IID candidates
D&C RED NO. 28	D&C RED NO. 28	767IP0Y5NH	POWDER, FOR SOLUTION / ORAL		3 mg	Exact identifier — unii+route 27 equally ranked IID candidates
D&C RED NO. 28	D&C RED NO. 28	767IP0Y5NH	CAPSULE, EXTENDED RELEASE / ORAL	0.2 mg		Exact identifier — unii+route 27 equally ranked IID candidates
D&C RED NO. 28	D&C RED NO. 28	767IP0Y5NH	CAPSULE, EXTENDED RELEASE / ORAL	0.2 mg		Exact identifier — unii+route 27 equally ranked IID candidates
D&C RED NO. 28	D&C RED NO. 28	767IP0Y5NH	CAPSULE, COATED PELLETS / ORAL	NA		Exact identifier — unii+route 27 equally ranked IID candidates
SACCHARIN SODIUM	SACCHARIN SODIUM	SB8ZUX40TY	LIQUID / ORAL		3 mg	Exact identifier — unii+route+dosage form 3 equally ranked IID candidates
SORBIC ACID	SORBIC ACID	X045WJ989B	SYRUP / ORAL		80 mg	Exact identifier — unii+route 30 equally ranked IID candidates
D&C RED NO. 22	D&C RED NO. 22	1678RKX8RT	SUSPENSION / ORAL	NA		Exact identifier — unii+route 15 equally ranked IID candidates
D&C RED NO. 28	D&C RED NO. 28	767IP0Y5NH	CAPSULE / ORAL		1 mg	Exact identifier — unii+route 27 equally ranked IID candidates
D&C RED NO. 22	D&C RED NO. 22	1678RKX8RT	CAPSULE, EXTENDED RELEASE / ORAL	NA		Exact identifier — unii+route 15 equally ranked IID candidates
BENZOIC ACID	BENZOIC ACID	8SKN0B0MIM	LIQUID / ORAL	2 mg/1ml		Exact identifier — unii+route+dosage form 3 equally ranked IID candidates
SORBIC ACID	SORBIC ACID	X045WJ989B	TABLET, FILM COATED, EXTENDED RELEASE / ORAL		1 mg	Exact identifier — unii+route 30 equally ranked IID candidates
D&C RED NO. 28	D&C RED NO. 28	767IP0Y5NH	CAPSULE, DELAYED RELEASE / ORAL		1 mg	Exact identifier — unii+route 27 equally ranked IID candidates
D&C RED NO. 28	D&C RED NO. 28	767IP0Y5NH	CAPSULE, DELAYED RELEASE / ORAL		1 mg	Exact identifier — unii+route 27 equally ranked IID candidates
SORBIC ACID	SORBIC ACID	X045WJ989B	SYRUP / ORAL		80 mg	Exact identifier — unii+route 30 equally ranked IID candidates
METHYLCELLULOSE (1500 MPA.S)	METHYLCELLULOSE (1500 MPA.S)	P0NTE48364	TABLET / ORAL		319 mg	Exact identifier — unii+route 3 equally ranked IID candidates
D&C RED NO. 22	D&C RED NO. 22	1678RKX8RT	CAPSULE / ORAL	0.02 mg		Exact identifier — unii+route 15 equally ranked IID candidates
D&C RED NO. 28	D&C RED NO. 28	767IP0Y5NH	POWDER, FOR SUSPENSION / ORAL	0.7 mg/5ml		Exact identifier — unii+route 27 equally ranked IID candidates
MAGNESIUM ALUMINUM SILICATE	MAGNESIUM ALUMINUM SILICATE	6M3P64V0NC	LIQUID / ORAL	82 mg/5ml		Exact identifier — unii+route+dosage form 3 equally ranked IID candidates
SORBIC ACID	SORBIC ACID	X045WJ989B	TABLET, FILM COATED / ORAL		5 mg	Exact identifier — unii+route 30 equally ranked IID candidates
D&C RED NO. 28	D&C RED NO. 28	767IP0Y5NH	SUSPENSION / ORAL	2.5 mg/5ml		Exact identifier — unii+route 27 equally ranked IID candidates
D&C RED NO. 28	D&C RED NO. 28	767IP0Y5NH	CAPSULE, COATED PELLETS / ORAL	NA		Exact identifier — unii+route 27 equally ranked IID candidates
SORBIC ACID	SORBIC ACID	X045WJ989B	TABLET, FILM COATED, EXTENDED RELEASE / ORAL		1 mg	Exact identifier — unii+route 30 equally ranked IID candidates

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Soothe	BISMUTH SUBSALICYLATE	Walgreens	a2b2b0ce-034e-4857-bfca-0087bb31878e	2024-07-25	Warnings	Exact identifier ndc (package): 0363-0073-16 ndc (package): 0363-0073-08 ndc (product): 0363-0073 ndc11 (package): 00363007308 ndc11 (package): 00363007316 spl id: 8451f30d-bd04-44e4-b0c1-29d9b04ecadc spl set id: a2b2b0ce-034e-4857-bfca-0087bb31878e

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.