Crest Pro-Health

Manufacturer: The Procter & Gamble Manufacturing Company
Effective date: 2026-01-08
Label type: HUMAN OTC DRUG LABEL
Version: 10
Source: monthly-update
Hydrated at: 2026-06-03 17:52:28

Label at a glance#

ProductCrest Pro-Health Clinical

Active ingredientCETYLPYRIDINIUM CHLORIDE

Label structure10 sections

Indications and uses

helps prevent and reduce plaque and gingivitis helps control plaque bacteria that contribute to the development of gingivitis and bleeding gums

Dosage and administration

use after your normal brushing and flossing routine; rinse toothpaste from mouth prior to use adults and children 12 yrs. & older: Rinse for 30 seconds with 20 mL (4 teaspoonfuls) twice a day do not swallow supervise use in children children under 12 years of age: do not use

Label contents#

Full prescribing information#

SPL UNCLASSIFIED SECTION

Drug Facts

Active ingredient

OTC - ACTIVE INGREDIENT SECTION

Cetylpyridinium chloride 0.1%

Purpose

OTC - PURPOSE SECTION

Antigingivitis/Antiplaque

Uses

INDICATIONS & USAGE SECTION

helps prevent and reduce plaque and gingivitis
helps control plaque bacteria that contribute to the development of gingivitis and bleeding gums

Warnings

WARNINGS SECTION

OTC - ASK DOCTOR/PHARMACIST SECTION

Ask a dentist if symptoms persist or condition worsens after regular use.

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

Keep out of reach of children under 12 years of age. If more than used for rinsing is accidentally swallowed, get medical help or contact a Poison Control Center right away.

Directions

DOSAGE & ADMINISTRATION SECTION

use after your normal brushing and flossing routine; rinse toothpaste from mouth prior to use
adults and children 12 yrs. & older: Rinse for 30 seconds with 20 mL (4 teaspoonfuls) twice a day
- do not swallow
- supervise use in children
children under 12 years of age: do not use

Inactive ingredients

INACTIVE INGREDIENT SECTION

water, glycerin, hydrogen peroxide, flavor, sucralose, poloxamer 407

Questions?

OTC - QUESTIONS SECTION

1–800–285–9139

SPL UNCLASSIFIED SECTION

Dist. by Procter & Gamble,
Cincinnati OH 45202

PRINCIPAL DISPLAY PANEL - 473 mL Bottle Label

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

Crest^®

PRO-HEALTH™

CPC ANTIGINGIVITIS/ANTIPLAQUE

ORAL RINSE

ALCOHOL FREE

CLINICAL

OUR MOST ADVANCED RINSE EVER

Reduces plaque & even helps prevent plaque regrowth
Helps prevent & even helps reverse gingivitis in 2 weeks
Kills 99% of germs to improve breath

DEEP CLEAN MINT

473mL

(16 FL OZ)

843

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	SPL version
1291375	cetylpyridinium chloride 0.1 % Mouthwash	PSN	10
1433894	Crest Pro-Health Clinical 0.1 % Oral Rinse	PSN	10
1433894	cetylpyridinium chloride 1 MG/ML Mouthwash [Crest Mouthwash]	SBD	10
1291375	cetylpyridinium chloride 1 MG/ML Mouthwash	SCD	10
1291375	cetylpyridinium chloride 0.1 % Mouthwash	SY	10
1433894	Crest Mouthwash 1 MG/ML Mouthwash	SY	10
1433894	Crest Pro-Health Clinical 0.1 % Mouthwash	SY	10

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
5eb9f24b-9328-475e-af0a-18021935eb6a	Product name	1	20180220

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDC	Effective	Action	Document	Indexing SPL	Related label
37000-843-08	2023-05-19	C162847	48780-1	ba0f9c33-1ded-a910-e053-dadaa90a0b85	Crest ® Pro-Health™ Clinical
37000-843-08	2023-05-19	C162847	48780-1	ba0f9c33-1ded-a910-e053-dadaa90a0b85	Crest ® Pro-Health™ Clinical
37000-843-16	2023-05-19	C162847	48780-1	ba0f9c33-1ded-a910-e053-dadaa90a0b85	Crest ® Pro-Health™ Clinical
37000-843-16	2023-05-19	C162847	48780-1	ba0f9c33-1ded-a910-e053-dadaa90a0b85	Crest ® Pro-Health™ Clinical
37000-843-32	2023-05-19	C162847	48780-1	ba0f9c33-1ded-a910-e053-dadaa90a0b85	Crest ® Pro-Health™ Clinical
37000-843-32	2023-05-19	C162847	48780-1	ba0f9c33-1ded-a910-e053-dadaa90a0b85	Crest ® Pro-Health™ Clinical
37000-843-08	2023-01-30	C162847	48780-1	ba0f9c33-1ded-a910-e053-dadaa90a0b85	Crest ® Pro-Health™ Clinical
37000-843-08	2023-01-30	C162847	48780-1	ba0f9c33-1ded-a910-e053-dadaa90a0b85	Crest ® Pro-Health™ Clinical
37000-843-16	2023-01-30	C162847	48780-1	ba0f9c33-1ded-a910-e053-dadaa90a0b85	Crest ® Pro-Health™ Clinical
37000-843-16	2023-01-30	C162847	48780-1	ba0f9c33-1ded-a910-e053-dadaa90a0b85	Crest ® Pro-Health™ Clinical
37000-843-32	2023-01-30	C162847	48780-1	ba0f9c33-1ded-a910-e053-dadaa90a0b85	Crest ® Pro-Health™ Clinical
37000-843-32	2023-01-30	C162847	48780-1	ba0f9c33-1ded-a910-e053-dadaa90a0b85	Crest ® Pro-Health™ Clinical
37000-843-08	2021-02-12	C162847	48780-1	ba0f9c33-1ded-a910-e053-dadaa90a0b85	Crest ® Pro-Health™ Clinical
37000-843-08	2021-02-12	C162847	48780-1	ba0f9c33-1ded-a910-e053-dadaa90a0b85	Crest ® Pro-Health™ Clinical
37000-843-16	2021-02-12	C162847	48780-1	ba0f9c33-1ded-a910-e053-dadaa90a0b85	Crest ® Pro-Health™ Clinical
37000-843-16	2021-02-12	C162847	48780-1	ba0f9c33-1ded-a910-e053-dadaa90a0b85	Crest ® Pro-Health™ Clinical
37000-843-32	2021-02-12	C162847	48780-1	ba0f9c33-1ded-a910-e053-dadaa90a0b85	Crest ® Pro-Health™ Clinical
37000-843-32	2021-02-12	C162847	48780-1	ba0f9c33-1ded-a910-e053-dadaa90a0b85	Crest ® Pro-Health™ Clinical
37000-843-08	2021-01-29	C162847	48780-1	ba0f9c33-1ded-a910-e053-dadaa90a0b85	Crest ® Pro-Health™ Clinical
37000-843-08	2021-01-29	C162847	48780-1	ba0f9c33-1ded-a910-e053-dadaa90a0b85	Crest ® Pro-Health™ Clinical
37000-843-16	2021-01-29	C162847	48780-1	ba0f9c33-1ded-a910-e053-dadaa90a0b85	Crest ® Pro-Health™ Clinical
37000-843-16	2021-01-29	C162847	48780-1	ba0f9c33-1ded-a910-e053-dadaa90a0b85	Crest ® Pro-Health™ Clinical
37000-843-32	2021-01-29	C162847	48780-1	ba0f9c33-1ded-a910-e053-dadaa90a0b85	Crest ® Pro-Health™ Clinical
37000-843-32	2021-01-29	C162847	48780-1	ba0f9c33-1ded-a910-e053-dadaa90a0b85	Crest ® Pro-Health™ Clinical

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
37000-843-08	Crest Pro-HealthClinical	237 mL in 1 BOTTLE, PLASTIC	RINSE	237	10
37000-843-16	Crest Pro-HealthClinical	473 mL in 1 BOTTLE, PLASTIC	RINSE	473	10
37000-843-32	Crest Pro-HealthClinical	946 mL in 1 BOTTLE, PLASTIC	RINSE	946	10

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	SPL version
Cetylpyridinium chloride	ACTIVE INGREDIENT	D9OM4SK49P	1
Cetylpyridinium	ACTIVE MOIETY	CUB7JI0JV3	1
Glycerin	INACTIVE INGREDIENT	PDC6A3C0OX	1
hydrogen peroxide	INACTIVE INGREDIENT	BBX060AN9V	1
poloxamer 407	INACTIVE INGREDIENT	TUF2IVW3M2	1
sucralose	INACTIVE INGREDIENT	96K6UQ3ZD4	1
water	INACTIVE INGREDIENT	059QF0KO0R	1

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 8 matching rows.

Crest Pro-Health Clinical
Cetylpyridinium chloride
GLYCERIN
HYDROGEN PEROXIDE
SUCRALOSE
POLOXAMER 407
CETYLPYRIDINIUM
WATER

NDC Codes#

Product NDC, Package NDC table
Product NDC	Package NDC
37000-843	37000-843-08, 37000-843-16, 37000-843-32

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 6 matching rows.

Name, UNII, Kind table
Name	UNII	Kind
GLYCERIN	PDC6A3C0OX	IACT
HYDROGEN PEROXIDE	BBX060AN9V	IACT
SUCRALOSE	96K6UQ3ZD4	IACT
POLOXAMER 407	TUF2IVW3M2	IACT
CETYLPYRIDINIUM CHLORIDE	D9OM4SK49P	ACTIB
WATER	059QF0KO0R	IACT

Source Document#

Source XML · Source PDF

Older Hydrated Versions#

Version, Effective date, Source table
Version	Effective date	Source	Hydrated
9	2025-07-31	full-release	2026-06-01 01:08:58

Inactive ingredient matches#

Inactive Ingredient Database values describe FDA-listed use contexts. The match method and ambiguity count are shown because ingredient names, routes, and dosage forms are not always unique. Browse recovered IID releases and source provenance.

Inactive ingredient links page 1 of 4 · 184 matching rows.

DailyMed ingredient, IID ingredient, UNII table
DailyMed ingredient	IID ingredient	UNII	Dosage form / route	Potency	Maximum daily exposure	Match
sucralose	SUCRALOSE	96K6UQ3ZD4	SUSPENSION / ORAL		383 mg	Exact identifier — unii+route 72 equally ranked IID candidates
Glycerin	GLYCERIN	PDC6A3C0OX	TABLET / ORAL		42 mg	Exact identifier — unii+route 80 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	FILM, SOLUBLE / ORAL		33 mg	Exact identifier — unii+route 72 equally ranked IID candidates
Glycerin	GLYCERIN	PDC6A3C0OX	TABLET, FILM COATED / ORAL	1.55 mg		Exact identifier — unii+route 80 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	LOZENGE / ORAL		115 mg	Exact identifier — unii+route 72 equally ranked IID candidates
poloxamer 407	POLOXAMER 407	TUF2IVW3M2	CAPSULE / ORAL		468 mg	Exact identifier — unii+route 28 equally ranked IID candidates
Glycerin	GLYCERIN	PDC6A3C0OX	ELIXIR / ORAL		5621 mg	Exact identifier — unii+route 80 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	FILM / ORAL		1 mg	Exact identifier — unii+route 72 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	GRANULE, FOR SUSPENSION / ORAL		23 mg	Exact identifier — unii+route 72 equally ranked IID candidates
Glycerin	GLYCERIN	PDC6A3C0OX	SUSPENSION / ORAL		26208 mg	Exact identifier — unii+route 80 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	TABLET, FOR SUSPENSION / ORAL		65 mg	Exact identifier — unii+route 72 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	TABLET / ORAL		45 mg	Exact identifier — unii+route 72 equally ranked IID candidates
Glycerin	GLYCERIN	PDC6A3C0OX	CAPSULE, EXTENDED RELEASE / ORAL		265 mg	Exact identifier — unii+route 80 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	POWDER, FOR SUSPENSION / ORAL		400 mg	Exact identifier — unii+route 72 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	TROCHE / ORAL		60 mg	Exact identifier — unii+route 72 equally ranked IID candidates
poloxamer 407	POLOXAMER 407	TUF2IVW3M2	CAPSULE, EXTENDED RELEASE / ORAL		40 mg	Exact identifier — unii+route 28 equally ranked IID candidates
poloxamer 407	POLOXAMER 407	TUF2IVW3M2	SOLUTION / ORAL	50 mg/5ml		Exact identifier — unii+route 28 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	SUSPENSION / ORAL		383 mg	Exact identifier — unii+route 72 equally ranked IID candidates
Glycerin	GLYCERIN	PDC6A3C0OX	TABLET, COATED / ORAL	1 mg		Exact identifier — unii+route 80 equally ranked IID candidates
Glycerin	GLYCERIN	PDC6A3C0OX	SUSPENSION/ DROPS / ORAL		750 mg	Exact identifier — unii+route 80 equally ranked IID candidates
Glycerin	GLYCERIN	PDC6A3C0OX	SUSPENSION / ORAL		26208 mg	Exact identifier — unii+route 80 equally ranked IID candidates
Glycerin	GLYCERIN	PDC6A3C0OX	SOLUTION / ORAL		32400 mg	Exact identifier — unii+route 80 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	POWDER, FOR SUSPENSION / ORAL		400 mg	Exact identifier — unii+route 72 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	TROCHE / ORAL		60 mg	Exact identifier — unii+route 72 equally ranked IID candidates
Glycerin	GLYCERIN	PDC6A3C0OX	CAPSULE, COATED / ORAL	14.21 mg		Exact identifier — unii+route 80 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	SUSPENSION, EXTENDED RELEASE / ORAL		16 mg	Exact identifier — unii+route 72 equally ranked IID candidates
Glycerin	GLYCERIN	PDC6A3C0OX	SOLUTION, CONCENTRATE / ORAL	200 mg/1ml		Exact identifier — unii+route 80 equally ranked IID candidates
Glycerin	GLYCERIN	PDC6A3C0OX	TABLET, COATED / ORAL	1 mg		Exact identifier — unii+route 80 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	SUSPENSION / ORAL		383 mg	Exact identifier — unii+route 72 equally ranked IID candidates
poloxamer 407	POLOXAMER 407	TUF2IVW3M2	CAPSULE, DELAYED RELEASE / ORAL		5 mg	Exact identifier — unii+route 28 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	TABLET, EFFERVESCENT / ORAL		1080 mg	Exact identifier — unii+route 72 equally ranked IID candidates
poloxamer 407	POLOXAMER 407	TUF2IVW3M2	CAPSULE, DELAYED RELEASE / ORAL		5 mg	Exact identifier — unii+route 28 equally ranked IID candidates
poloxamer 407	POLOXAMER 407	TUF2IVW3M2	CAPSULE, DELAYED RELEASE / ORAL		5 mg	Exact identifier — unii+route 28 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	SYRUP / ORAL		80 mg	Exact identifier — unii+route 72 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	SOLUTION / ORAL		800 mg	Exact identifier — unii+route 72 equally ranked IID candidates
Glycerin	GLYCERIN	PDC6A3C0OX	PASTE / ORAL		3822 mg	Exact identifier — unii+route 80 equally ranked IID candidates
Glycerin	GLYCERIN	PDC6A3C0OX	TABLET, CHEWABLE / ORAL		12 mg	Exact identifier — unii+route 80 equally ranked IID candidates
Glycerin	GLYCERIN	PDC6A3C0OX	LIQUID / ORAL		2400 mg	Exact identifier — unii+route 80 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	TABLET, FOR SUSPENSION / ORAL		65 mg	Exact identifier — unii+route 72 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	LOZENGE / ORAL		115 mg	Exact identifier — unii+route 72 equally ranked IID candidates
Glycerin	GLYCERIN	PDC6A3C0OX	TABLET, FILM COATED / ORAL	1.55 mg		Exact identifier — unii+route 80 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	GRANULE, FOR SUSPENSION / ORAL		23 mg	Exact identifier — unii+route 72 equally ranked IID candidates
Glycerin	GLYCERIN	PDC6A3C0OX	TABLET, EXTENDED RELEASE / ORAL		7 mg	Exact identifier — unii+route 80 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	TABLET, EFFERVESCENT / ORAL		1080 mg	Exact identifier — unii+route 72 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	TABLET, ORALLY DISINTEGRATING / ORAL		60 mg	Exact identifier — unii+route 72 equally ranked IID candidates
Glycerin	GLYCERIN	PDC6A3C0OX	SOLUTION, CONCENTRATE / ORAL	200 mg/1ml		Exact identifier — unii+route 80 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	SUSPENSION / ORAL		383 mg	Exact identifier — unii+route 72 equally ranked IID candidates
Glycerin	GLYCERIN	PDC6A3C0OX	CAPSULE / ORAL		3487 mg	Exact identifier — unii+route 80 equally ranked IID candidates
Glycerin	GLYCERIN	PDC6A3C0OX	SOLUTION / ORAL		32400 mg	Exact identifier — unii+route 80 equally ranked IID candidates
Glycerin	GLYCERIN	PDC6A3C0OX	TABLET / ORAL		42 mg	Exact identifier — unii+route 80 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	LOZENGE / ORAL		115 mg	Exact identifier — unii+route 72 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	POWDER, FOR SOLUTION / ORAL		414 mg	Exact identifier — unii+route 72 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	SOLUTION / ORAL		800 mg	Exact identifier — unii+route 72 equally ranked IID candidates
poloxamer 407	POLOXAMER 407	TUF2IVW3M2	TABLET / ORAL		495 mg	Exact identifier — unii+route 28 equally ranked IID candidates
poloxamer 407	POLOXAMER 407	TUF2IVW3M2	POWDER, FOR SUSPENSION / ORAL	0.01 mg		Exact identifier — unii+route 28 equally ranked IID candidates
hydrogen peroxide	HYDROGEN PEROXIDE	BBX060AN9V	TABLET, DELAYED RELEASE / ORAL	NA		Exact identifier — unii+route 4 equally ranked IID candidates
sucralose	SUCRALOSE	96K6UQ3ZD4	TABLET, ORALLY DISINTEGRATING / ORAL		60 mg	Exact identifier — unii+route 72 equally ranked IID candidates
Glycerin	GLYCERIN	PDC6A3C0OX	PASTE / ORAL		3822 mg	Exact identifier — unii+route 80 equally ranked IID candidates
Glycerin	GLYCERIN	PDC6A3C0OX	PASTE / ORAL		3822 mg	Exact identifier — unii+route 80 equally ranked IID candidates
Glycerin	GLYCERIN	PDC6A3C0OX	SUSPENSION, EXTENDED RELEASE / ORAL		2000 mg	Exact identifier — unii+route 80 equally ranked IID candidates

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Crest Pro-Health Clinical	CETYLPYRIDINIUM CHLORIDE	The Procter & Gamble Manufacturing Company	0a295ee0-55c2-4f21-8f0a-70efc0e51694	2026-01-08	Warnings	Exact identifier ndc (package): 37000-843-16 ndc (package): 37000-843-32 ndc (package): 37000-843-08 ndc (product): 37000-843 ndc11 (package): 37000084316 ndc11 (package): 37000084308 ndc11 (package): 37000084332 spl id: 47e49363-ea07-b3c5-e063-6294a90acf3c spl set id: 0a295ee0-55c2-4f21-8f0a-70efc0e51694

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.