Crest 3D White Brilliance

Manufacturer: The Procter & Gamble Manufacturing Company
Effective date: 2026-01-08
Label type: HUMAN OTC DRUG LABEL
Version: 9
Source: monthly-update
Hydrated at: 2026-06-03 17:52:18

Label at a glance#

ProductCrest 3D White Brilliance Daily Cleansing and Whitening System

Active ingredientSTANNOUS FLUORIDE

Label structure11 sections

Indications and uses

aids in the prevention of cavities helps prevent gingivitis helps interfere with the harmful effects of plaque associated with gingivitis helps control plaque bacteria that contribute to the development of gingivitis

Dosage and administration

adults and children 12 yrs. of age and older: Brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or physician. do not swallow children under 12 yrs. of age: ask a dentist

Storage and handling

products containing stannous fluoride may produce surface staining of the teeth adequate toothbrushing may prevent these stains which are not harmful or permanent and may be removed by your dentist see your dentist regularly

Contacts and useful links#

PhoneLabel contact1 (800) 492-7378

Label contents#

Full prescribing information#

SPL UNCLASSIFIED SECTION

Drug Facts

Active ingredient

OTC - ACTIVE INGREDIENT SECTION

Stannous fluoride 0.454% (0.15% w/v fluoride ion)

Purposes

OTC - PURPOSE SECTION

Anticavity, antigingivitis toothpaste

Uses

INDICATIONS & USAGE SECTION

aids in the prevention of cavities
helps prevent gingivitis
helps interfere with the harmful effects of plaque associated with gingivitis
helps control plaque bacteria that contribute to the development of gingivitis

Warning

WARNINGS SECTION

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

Keep out of reach of children under 12 yrs. of age. If more than used for brushing is accidentally swallowed, get medical help or contact a Poison Control Center right away.

Directions

DOSAGE & ADMINISTRATION SECTION

adults and children 12 yrs. of age and older: Brush teeth thoroughly, preferably after each meal or at least twice a day, or as directed by a dentist or physician.
do not swallow
children under 12 yrs. of age: ask a dentist

Other information

STORAGE AND HANDLING SECTION

products containing stannous fluoride may produce surface staining of the teeth
adequate toothbrushing may prevent these stains which are not harmful or permanent and may be removed by your dentist
see your dentist regularly

Inactive ingredients

INACTIVE INGREDIENT SECTION

glycerin, hydrated silica, water, zinc lactate, sodium lauryl sulfate, trisodium phosphate, flavor, sodium gluconate, sodium saccharin, xanthan gum, cellulose gum, sodium hydroxide, mica, titanium dioxide

Questions?

OTC - QUESTIONS SECTION

1 (800) 492-7378

SPL UNCLASSIFIED SECTION

DISTR. BY PROCTER & GAMBLE,
CINCINNATI, OH 45202

PRINCIPAL DISPLAY PANEL - Kit Carton

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

DAILY WHITENING 2-STEP TREATMENT

Crest BRILLIANCE

3D WHITE WHITENING 2-STEP

FLUORIDE TOOTHPASTE FOR ANTICAVITY AND ANTIGINGIVITIS - WHITENING GEL

KEEPS YOUR SMILE UP TO 99%

AS WHITE AS A PROFESSIONAL POLISH

NET WT 1 TUBE 4.0 OZ (113 g) & 1 TUBE 2.3 OZ (65 g)

Label

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	SPL version
416784	stannous fluoride 0.454 % (fluoride ion 0.16 % ) Toothpaste	PSN	9
416784	stannous fluoride 0.00454 MG/MG Toothpaste	SCD	9
416784	stannous fluoride 0.454 % (fluoride ion 0.14 % ) Toothpaste	SY	9
416784	stannous fluoride 0.454 % (fluoride ion 0.15 % ) Toothpaste	SY	9
416784	stannous fluoride 0.454 % (fluoride ion 0.16 % ) Toothpaste	SY	9

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
6bd95106-a412-1dad-b9cc-4cb74bfb27ce	Product name	2	20230315
5eb9f24b-9328-475e-af0a-18021935eb6a	Product name	1	20180220
290f523a-f9db-9774-b5a9-e1f908ac1782	Product name	1	20150828
c6b65c52-69c7-df49-550a-a50c137f6218	Product name	1	20140508

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDC	Effective	Action	Document	Indexing SPL	Related label
37000-863-04	2023-03-30	C162847	48780-1	ba0f9c33-32d9-a910-e053-dadaa90a0b85	Crest ® 3D White™ Brilliance Daily Cleansing and Whitening System
37000-863-04	2023-03-30	C162847	48780-1	ba0f9c33-32d9-a910-e053-dadaa90a0b85	Crest ® 3D White™ Brilliance Daily Cleansing and Whitening System
37000-863-04	2023-01-30	C162847	48780-1	ba0f9c33-32d9-a910-e053-dadaa90a0b85	Crest ® 3D White™ Brilliance Daily Cleansing and Whitening System
37000-863-04	2023-01-30	C162847	48780-1	ba0f9c33-32d9-a910-e053-dadaa90a0b85	Crest ® 3D White™ Brilliance Daily Cleansing and Whitening System
37000-863-04	2021-02-12	C162847	48780-1	ba0f9c33-32d9-a910-e053-dadaa90a0b85	Crest ® 3D White™ Brilliance Daily Cleansing and Whitening System
37000-863-04	2021-02-12	C162847	48780-1	ba0f9c33-32d9-a910-e053-dadaa90a0b85	Crest ® 3D White™ Brilliance Daily Cleansing and Whitening System
37000-863-04	2021-01-29	C162847	48780-1	ba0f9c33-32d9-a910-e053-dadaa90a0b85	Crest ® 3D White™ Brilliance Daily Cleansing and Whitening System
37000-863-04	2021-01-29	C162847	48780-1	ba0f9c33-32d9-a910-e053-dadaa90a0b85	Crest ® 3D White™ Brilliance Daily Cleansing and Whitening System

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
37000-863-04	Crest 3D White BrillianceDaily Cleansing and Whitening System	1 in 1 CARTON	KIT	1		9

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	SPL version
Stannous Fluoride	ACTIVE INGREDIENT	3FTR44B32Q	1
Fluoride Ion	ACTIVE MOIETY	Q80VPU408O	1
carboxymethylcellulose sodium	INACTIVE INGREDIENT	K679OBS311	1
glycerin	INACTIVE INGREDIENT	PDC6A3C0OX	1
hydrated silica	INACTIVE INGREDIENT	Y6O7T4G8P9	1
mica	INACTIVE INGREDIENT	V8A1AW0880	1
saccharin sodium	INACTIVE INGREDIENT	SB8ZUX40TY	1
sodium gluconate	INACTIVE INGREDIENT	R6Q3791S76	1
sodium hydroxide	INACTIVE INGREDIENT	55X04QC32I	1
sodium lauryl sulfate	INACTIVE INGREDIENT	368GB5141J	1
titanium dioxide	INACTIVE INGREDIENT	15FIX9V2JP	1
water	INACTIVE INGREDIENT	059QF0KO0R	1
xanthan gum	INACTIVE INGREDIENT	TTV12P4NEE	1
zinc lactate	INACTIVE INGREDIENT	2GXR25858Y	1

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 20 matching rows.

Crest 3D White Brilliance Daily Cleansing and Whitening System
Stannous Fluoride
Crest 3D White Step 1 Purifying Cleanser
GLYCERIN
HYDRATED SILICA
WATER
ZINC LACTATE
SODIUM LAURYL SULFATE
SODIUM GLUCONATE
SACCHARIN SODIUM
XANTHAN GUM
CARBOXYMETHYLCELLULOSE SODIUM
SODIUM HYDROXIDE
MICA
TITANIUM DIOXIDE
FLUORIDE ION
Crest 3D White Step 2 Whitening Gel
HYDROGEN PEROXIDE
SODIUM ACID PYROPHOSPHATE
SUCRALOSE

NDC Codes#

Product NDC, Package NDC table
Product NDC	Package NDC
37000-863	37000-863-04

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 19 matching rows.

Name, UNII, Kind table
Name	UNII	Kind
GLYCERIN	PDC6A3C0OX	IACT
HYDRATED SILICA	Y6O7T4G8P9	IACT
WATER	059QF0KO0R	IACT
ZINC LACTATE	2GXR25858Y	IACT
SODIUM LAURYL SULFATE	368GB5141J	IACT
SODIUM GLUCONATE	R6Q3791S76	IACT
SACCHARIN SODIUM	SB8ZUX40TY	IACT
XANTHAN GUM	TTV12P4NEE	IACT
CARBOXYMETHYLCELLULOSE SODIUM	K679OBS311	IACT
SODIUM HYDROXIDE	55X04QC32I	IACT
MICA	V8A1AW0880	IACT
TITANIUM DIOXIDE	15FIX9V2JP	IACT
STANNOUS FLUORIDE	3FTR44B32Q	ACTIM
WATER	059QF0KO0R	INGR
GLYCERIN	PDC6A3C0OX	INGR
HYDROGEN PEROXIDE	BBX060AN9V	INGR
SODIUM ACID PYROPHOSPHATE	H5WVD9LZUD	INGR
SUCRALOSE	96K6UQ3ZD4	INGR
SODIUM HYDROXIDE	55X04QC32I	INGR

Source Document#

Source XML

Older Hydrated Versions#

Version, Effective date, Source table
Version	Effective date	Source	Hydrated
8	2025-01-14	full-release	2026-06-01 00:52:41

Inactive ingredient matches#

Inactive Ingredient Database values describe FDA-listed use contexts. The match method and ambiguity count are shown because ingredient names, routes, and dosage forms are not always unique. Browse recovered IID releases and source provenance.

Inactive ingredient links page 1 of 15 · 882 matching rows.

DailyMed ingredient, IID ingredient, UNII table
DailyMed ingredient	IID ingredient	UNII	Dosage form / route	Potency	Maximum daily exposure	Match
glycerin	GLYCERIN	PDC6A3C0OX	INJECTION / SUBCUTANEOUS		450 mg	Exact identifier — unii candidate 150 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	TABLET, CHEWABLE, EXTENDED RELEASE / ORAL		1 mg	Exact identifier — unii candidate 84 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	GEL / TOPICAL	0.05 %w/w		Exact identifier — unii candidate 84 equally ranked IID candidates
glycerin	GLYCERIN	PDC6A3C0OX	AEROSOL / TOPICAL	3 %w/w		Exact identifier — unii candidate 150 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION / SUBCUTANEOUS	ADJ PH		Exact identifier — unii candidate 348 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	SOLUTION / URETERAL	ADJ PH		Exact identifier — unii candidate 348 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	INJECTION, SUSPENSION, LIPOSOMAL / INTRAVENOUS	ADJ PH		Exact identifier — unii candidate 348 equally ranked IID candidates
titanium dioxide	TITANIUM DIOXIDE	15FIX9V2JP	INSERT, EXTENDED RELEASE / OPHTHALMIC	0.4 mg		Exact identifier — unii candidate 80 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	TABLET, CHEWABLE, EXTENDED RELEASE / ORAL		1 mg	Exact identifier — unii candidate 84 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	TABLET, FILM COATED / ORAL		8 mg	Exact identifier — unii candidate 348 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	LOTION, AUGMENTED / TOPICAL	ADJ PH		Exact identifier — unii candidate 348 equally ranked IID candidates
carboxymethylcellulose sodium	CARBOXYMETHYLCELLULOSE SODIUM	K679OBS311	INJECTION / INTRAMUSCULAR		30 mg	Exact identifier — unii candidate 88 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	MOUTHWASH / BUCCAL	2 mg/1ml		Exact identifier — unii candidate 348 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	INJECTION / INTRASYNOVIAL	ADJ PH		Exact identifier — unii candidate 348 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	SOLUTION / EPIDURAL	ADJ PH		Exact identifier — unii candidate 348 equally ranked IID candidates
saccharin sodium	SACCHARIN SODIUM	SB8ZUX40TY	SUSPENSION / ORAL	5000 mg/5ml		Exact identifier — unii candidate 68 equally ranked IID candidates
carboxymethylcellulose sodium	CARBOXYMETHYLCELLULOSE SODIUM	K679OBS311	INJECTION / INTRASYNOVIAL	0.1 %w/v		Exact identifier — unii candidate 88 equally ranked IID candidates
glycerin	GLYCERIN	PDC6A3C0OX	INJECTION / INTRADERMAL	1.6 %w/v		Exact identifier — unii candidate 150 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	CREAM / TOPICAL		69 mg	Exact identifier — unii candidate 348 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	CREAM / VAGINAL	0.19 %w/w		Exact identifier — unii candidate 348 equally ranked IID candidates
glycerin	GLYCERIN	PDC6A3C0OX	SOLUTION / RESPIRATORY (INHALATION)	5 %w/w		Exact identifier — unii candidate 150 equally ranked IID candidates
glycerin	GLYCERIN	PDC6A3C0OX	SUSPENSION, EXTENDED RELEASE / ORAL		2000 mg	Exact identifier — unii candidate 150 equally ranked IID candidates
glycerin	GLYCERIN	PDC6A3C0OX	SOLUTION/ DROPS / OPHTHALMIC		12 mg	Exact identifier — unii candidate 150 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	SUSPENSION / SUBCUTANEOUS	ADJ PH		Exact identifier — unii candidate 348 equally ranked IID candidates
glycerin	GLYCERIN	PDC6A3C0OX	SOLUTION / TOPICAL		1971 mg	Exact identifier — unii candidate 150 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	LOTION / TOPICAL		21 mg	Exact identifier — unii candidate 348 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	GEL / TOPICAL		70 mg	Exact identifier — unii candidate 348 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	INJECTION, SOLUTION / INTRAVASCULAR	ADJ PH		Exact identifier — unii candidate 348 equally ranked IID candidates
titanium dioxide	TITANIUM DIOXIDE	15FIX9V2JP	CAPSULE, COATED, EXTENDED RELEASE / ORAL	NA		Exact identifier — unii candidate 80 equally ranked IID candidates
sodium gluconate	SODIUM GLUCONATE	R6Q3791S76	TABLET / ORAL	59 mg		Exact identifier — unii candidate 6 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	LIQUID / ORAL	2 mg/5ml		Exact identifier — unii candidate 348 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	INJECTION, SOLUTION / INTRA-ARTICULAR	ADJ PH		Exact identifier — unii candidate 348 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	INJECTION / INTRATUMOR	ADJ PH		Exact identifier — unii candidate 348 equally ranked IID candidates
carboxymethylcellulose sodium	CARBOXYMETHYLCELLULOSE SODIUM	K679OBS311	FILM / BUCCAL		18 mg	Exact identifier — unii candidate 88 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	INJECTION, POWDER, FOR SOLUTION / INTRA-ARTERIAL	ADJ PH		Exact identifier — unii candidate 348 equally ranked IID candidates
glycerin	GLYCERIN	PDC6A3C0OX	GEL / OPHTHALMIC	0.88 %w/w		Exact identifier — unii candidate 150 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	INJECTION, SOLUTION / INTRA-ARTICULAR	ADJ PH		Exact identifier — unii candidate 348 equally ranked IID candidates
carboxymethylcellulose sodium	CARBOXYMETHYLCELLULOSE SODIUM	K679OBS311	SUSPENSION/ DROPS / ORAL	12.85 mg/2.5ml		Exact identifier — unii candidate 88 equally ranked IID candidates
xanthan gum	XANTHAN GUM	TTV12P4NEE	TABLET, CHEWABLE, EXTENDED RELEASE / ORAL		6 mg	Exact identifier — unii candidate 58 equally ranked IID candidates
carboxymethylcellulose sodium	CARBOXYMETHYLCELLULOSE SODIUM	K679OBS311	SUSPENSION / ORAL		1080 mg	Exact identifier — unii candidate 88 equally ranked IID candidates
saccharin sodium	SACCHARIN SODIUM	SB8ZUX40TY	OINTMENT / DENTAL	NA		Exact identifier — unii candidate 68 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	INJECTION / INTRABURSAL	ADJ PH		Exact identifier — unii candidate 348 equally ranked IID candidates
glycerin	GLYCERIN	PDC6A3C0OX	SOLUTION / NASAL	25 mg/1ml		Exact identifier — unii candidate 150 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	INJECTION / INTRAVENOUS		456 mg	Exact identifier — unii candidate 348 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	INJECTION / INTRA-ARTERIAL	176 mg		Exact identifier — unii candidate 348 equally ranked IID candidates
glycerin	GLYCERIN	PDC6A3C0OX	TABLET, FILM COATED / ORAL	1.55 mg		Exact identifier — unii candidate 150 equally ranked IID candidates
titanium dioxide	TITANIUM DIOXIDE	15FIX9V2JP	POWDER, FOR SUSPENSION / ORAL		297 mg	Exact identifier — unii candidate 80 equally ranked IID candidates
glycerin	GLYCERIN	PDC6A3C0OX	PASTE / ORAL		3822 mg	Exact identifier — unii candidate 150 equally ranked IID candidates
carboxymethylcellulose sodium	CARBOXYMETHYLCELLULOSE SODIUM	K679OBS311	CAPSULE, EXTENDED RELEASE / ORAL		4 mg	Exact identifier — unii candidate 88 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	INJECTION / INTRASYNOVIAL	ADJ PH		Exact identifier — unii candidate 348 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	SOLUTION / RESPIRATORY (INHALATION)	8 %w/v		Exact identifier — unii candidate 348 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	SOLUTION / INTRAOCULAR	ADJ PH		Exact identifier — unii candidate 348 equally ranked IID candidates
glycerin	GLYCERIN	PDC6A3C0OX	SPRAY / NASAL	22.3 mg/1ml		Exact identifier — unii candidate 150 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	EMULSION / OPHTHALMIC	0.02 %w/v		Exact identifier — unii candidate 348 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION / INTRATHECAL	ADJ PH		Exact identifier — unii candidate 348 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	TABLET, DELAYED RELEASE / ORAL		199 mg	Exact identifier — unii candidate 84 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	INJECTION / INTRAVASCULAR	ADJ PH		Exact identifier — unii candidate 348 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	INJECTION, SUSPENSION, LIPOSOMAL / INTRAVENOUS	ADJ PH		Exact identifier — unii candidate 348 equally ranked IID candidates
xanthan gum	XANTHAN GUM	TTV12P4NEE	GRANULE, FOR SUSPENSION, EXTENDED RELEASE / ORAL		2350 mg	Exact identifier — unii candidate 58 equally ranked IID candidates
sodium hydroxide	SODIUM HYDROXIDE	55X04QC32I	SOLUTION / SUBCUTANEOUS	ADJ PH		Exact identifier — unii candidate 348 equally ranked IID candidates

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Crest 3D White Brilliance Daily Cleansing and Whitening System	STANNOUS FLUORIDE	The Procter & Gamble Manufacturing Company	89a6fb36-5109-47f1-95ad-9381471ceeef	2026-01-08	Warnings	Exact identifier ndc (package): 37000-863-04 ndc (product): 37000-863 ndc11 (package): 37000086304 spl id: 47e4a85d-a3e6-ba6a-e063-6294a90a251d spl set id: 89a6fb36-5109-47f1-95ad-9381471ceeef

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.