Indications and uses
helps prevent recurrence of flaking and itching associated with dandruff.
Head and Shoulders
- Manufacturer
- The Procter & Gamble Manufacturing Company
- Effective date
- 2026-03-12
- Label type
- HUMAN OTC DRUG LABEL
- Version
- 14
- Source
- monthly-update
- Hydrated at
- 2026-07-17 21:36:41
Label at a glance#
ProductHead and Shoulders Green Apple 2in1
Active ingredientPYRITHIONE ZINC
Label structure10 sections
Dosage and administration
for best results use at least twice a week or as directed by a doctor. for maximum dandruff control, use every time you shampoo. shake before use. wet hair, massage onto scalp, rinse, repeat if desired.
Contacts and useful links#
Label contents#
Full prescribing information#
SPL UNCLASSIFIED SECTION
Drug Facts
Active ingredient
Pyrithione zinc 1%
Purpose
Anti-dandruff
Uses
helps prevent recurrence of flaking and itching associated with dandruff.
Warnings
For external use only.
When using this product
- avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water.
Stop use and ask a doctor if
- condition worsens or does not improve after regular use of this product as directed.
OTC - KEEP OUT OF REACH OF CHILDREN SECTION
Keep this and all drugs out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
Directions
- for best results use at least twice a week or as directed by a doctor.
- for maximum dandruff control, use every time you shampoo.
- shake before use.
- wet hair, massage onto scalp, rinse, repeat if desired.
Inactive ingredients
Water, sodium lauryl sulfate, sodium laureth sulfate, glycol distearate, sodium chloride, zinc carbonate, dimethicone, cocamidopropyl betaine, sodium xylenesulfonate, fragrance, sodium benzoate, guar hydroxypropyltrimonium chloride, magnesium carbonate hydroxide, yellow 5, blue 1
Questions (or comments)?
1-800-723-9569
SPL UNCLASSIFIED SECTION
Dist. by PROCTER & GAMBLE,
CINCINNATI, OH 45202
PRINCIPAL DISPLAY PANEL - 370 mL Bottle Label
head &
shoulders
®
pyrithione zinc
dandruff
shampoo + conditioner
Green Apple
2in
1
with a lasting fresh scent
FLAKE FREE.*
UP TO 100%
GUARANTEED^
12.5 FL OZ (370 mL)
FDA-Initiated Inactive NDC Indexing#
DailyMed Socrata Ingredients#
| Ingredient | Type | UNII | SPL version | Uploaded |
|---|---|---|---|---|
| Pyrithione Zinc | ACTIVE INGREDIENT | R953O2RHZ5 | 3 | |
| Pyrithione Zinc | ACTIVE MOIETY | R953O2RHZ5 | 3 | |
| cocamidopropyl betaine | INACTIVE INGREDIENT | 5OCF3O11KX | 3 | |
| dimethicone | INACTIVE INGREDIENT | 92RU3N3Y1O | 3 | |
| FD&C blue no. 1 | INACTIVE INGREDIENT | H3R47K3TBD | 3 | |
| FD&C yellow no. 5 | INACTIVE INGREDIENT | I753WB2F1M | 3 | |
| glycol distearate | INACTIVE INGREDIENT | 13W7MDN21W | 3 | |
| magnesium carbonate hydroxide | INACTIVE INGREDIENT | YQO029V1L4 | 3 | |
| methylchloroisothiazolinone | INACTIVE INGREDIENT | DEL7T5QRPN | 3 | |
| methylisothiazolinone | INACTIVE INGREDIENT | 229D0E1QFA | 3 | |
| sodium benzoate | INACTIVE INGREDIENT | OJ245FE5EU | 3 | |
| sodium chloride | INACTIVE INGREDIENT | 451W47IQ8X | 3 | |
| sodium laureth-3 sulfate | INACTIVE INGREDIENT | BPV390UAP0 | 3 | |
| sodium lauryl sulfate | INACTIVE INGREDIENT | 368GB5141J | 3 | |
| sodium xylenesulfonate | INACTIVE INGREDIENT | G4LZF950UR | 3 | |
| water | INACTIVE INGREDIENT | 059QF0KO0R | 3 | |
| zinc carbonate | INACTIVE INGREDIENT | EQR32Y7H0M | 3 |
Products#
Every source-derived product name is available through these pages.
- Head and Shoulders Green Apple 2in1
- Pyrithione Zinc
- FD&C YELLOW NO. 5
- WATER
- SODIUM LAURYL SULFATE
- SODIUM LAURETH-3 SULFATE
- GLYCOL DISTEARATE
- ZINC CARBONATE
- SODIUM CHLORIDE
- SODIUM XYLENESULFONATE
- DIMETHICONE
- COCAMIDOPROPYL BETAINE
- SODIUM BENZOATE
- MAGNESIUM CARBONATE HYDROXIDE
- GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE (1.7 SUBSTITUENTS PER SACCHARIDE)
- FD&C BLUE NO. 1
NDC Codes#
| Product NDC | Package NDC |
|---|---|
| 37000-078 | 37000-078-70, 37000-078-40, 37000-078-25, 37000-078-01, 37000-078-11, 37000-078-95, 37000-078-12, 37000-078-02, 37000-078-37, 37000-078-61, 37000-078-83 |
Ingredients#
Every source-derived ingredient row is available through these pages.
Source Document#
Older Hydrated Versions#
| Version | Effective date | Source | Hydrated |
|---|---|---|---|
| 13 | 2025-12-18 | full-release | 2026-06-01 01:26:35 |
Inactive ingredient matches#
Inactive Ingredient Database values describe FDA-listed use contexts. The match method and ambiguity count are shown because ingredient names, routes, and dosage forms are not always unique. Browse recovered IID releases and source provenance.
| DailyMed ingredient | IID ingredient | UNII | Dosage form / route | Potency | Maximum daily exposure | Match |
|---|---|---|---|---|---|---|
| sodium benzoate | SODIUM BENZOATE | OJ245FE5EU | SOLUTION / TOPICAL | 0.1 %w/v | ||
| sodium lauryl sulfate | SODIUM LAURYL SULFATE | 368GB5141J | SPONGE / TOPICAL | 5 %w/w | ||
| FD&C blue no. 1 | FD&C BLUE NO. 1 | H3R47K3TBD | SHAMPOO / TOPICAL | 0.75 %w/w | ||
| sodium benzoate | SODIUM BENZOATE | OJ245FE5EU | CREAM / TOPICAL | 0.2 %w/w | ||
| FD&C blue no. 1 | FD&C BLUE NO. 1 | H3R47K3TBD | SHAMPOO / TOPICAL | 0.75 %w/w | ||
| sodium lauryl sulfate | SODIUM LAURYL SULFATE | 368GB5141J | OINTMENT / TOPICAL | 14 mg | ||
| sodium chloride | SODIUM CHLORIDE | 451W47IQ8X | SOLUTION / TOPICAL | 210 mg | ||
| FD&C blue no. 1 | FD&C BLUE NO. 1 | H3R47K3TBD | LOTION / TOPICAL | NA | ||
| FD&C blue no. 1 | FD&C BLUE NO. 1 | H3R47K3TBD | LIQUID / TOPICAL | NA | ||
| sodium lauryl sulfate | SODIUM LAURYL SULFATE | 368GB5141J | LOTION / TOPICAL | 111 mg | ||
| FD&C yellow no. 5 | FD&C YELLOW NO. 5 | I753WB2F1M | SOLUTION / TOPICAL | 0.06 %w/w | ||
| sodium laureth-3 sulfate | SODIUM LAURETH-3 SULFATE | BPV390UAP0 | CREAM / TOPICAL | NA | ||
| sodium chloride | SODIUM CHLORIDE | 451W47IQ8X | SHAMPOO / TOPICAL | 150 mg | ||
| sodium chloride | SODIUM CHLORIDE | 451W47IQ8X | SYSTEM / TOPICAL | 3.1 mg | ||
| sodium benzoate | SODIUM BENZOATE | OJ245FE5EU | GEL / TOPICAL | 5 mg | ||
| sodium benzoate | SODIUM BENZOATE | OJ245FE5EU | SPONGE / TOPICAL | NA | ||
| sodium chloride | SODIUM CHLORIDE | 451W47IQ8X | SUSPENSION / TOPICAL | 0.32 %w/v | ||
| sodium laureth-3 sulfate | SODIUM LAURETH-3 SULFATE | BPV390UAP0 | SHAMPOO / TOPICAL | 3192 mg | ||
| FD&C blue no. 1 | FD&C BLUE NO. 1 | H3R47K3TBD | SOAP / TOPICAL | 0.01 %w/w | ||
| sodium laureth-3 sulfate | SODIUM LAURETH-3 SULFATE | BPV390UAP0 | CREAM / TOPICAL | NA | ||
| sodium benzoate | SODIUM BENZOATE | OJ245FE5EU | GEL / TOPICAL | 5 mg | ||
| sodium chloride | SODIUM CHLORIDE | 451W47IQ8X | SUSPENSION / TOPICAL | 0.32 %w/v | ||
| sodium lauryl sulfate | SODIUM LAURYL SULFATE | 368GB5141J | SHAMPOO / TOPICAL | 65 %w/w | ||
| FD&C blue no. 1 | FD&C BLUE NO. 1 | H3R47K3TBD | SHAMPOO / TOPICAL | 0.75 %w/w | ||
| sodium lauryl sulfate | SODIUM LAURYL SULFATE | 368GB5141J | OINTMENT / TOPICAL | 14 mg | ||
| sodium benzoate | SODIUM BENZOATE | OJ245FE5EU | SOLUTION / TOPICAL | 0.1 %w/v | ||
| sodium laureth-3 sulfate | SODIUM LAURETH-3 SULFATE | BPV390UAP0 | CREAM / TOPICAL | NA | ||
| sodium chloride | SODIUM CHLORIDE | 451W47IQ8X | GEL / TOPICAL | 0.18 %w/w | ||
| sodium benzoate | SODIUM BENZOATE | OJ245FE5EU | GEL / TOPICAL | 5 mg | ||
| sodium chloride | SODIUM CHLORIDE | 451W47IQ8X | LOTION / TOPICAL | 0.3 %w/v | ||
| sodium laureth-3 sulfate | SODIUM LAURETH-3 SULFATE | BPV390UAP0 | CREAM / TOPICAL | NA | ||
| sodium lauryl sulfate | SODIUM LAURYL SULFATE | 368GB5141J | CREAM / TOPICAL | 214 mg | ||
| sodium chloride | SODIUM CHLORIDE | 451W47IQ8X | CREAM / TOPICAL | 0.4 %w/w | ||
| sodium lauryl sulfate | SODIUM LAURYL SULFATE | 368GB5141J | SPRAY / TOPICAL | 7 mg | ||
| sodium chloride | SODIUM CHLORIDE | 451W47IQ8X | SYSTEM / TOPICAL | 3.1 mg | ||
| FD&C blue no. 1 | FD&C BLUE NO. 1 | H3R47K3TBD | SOAP / TOPICAL | 0.01 %w/w | ||
| sodium chloride | SODIUM CHLORIDE | 451W47IQ8X | SUSPENSION/ DROPS / TOPICAL | 0.23 %w/v | ||
| FD&C yellow no. 5 | FD&C YELLOW NO. 5 | I753WB2F1M | POWDER / TOPICAL | NA | ||
| sodium chloride | SODIUM CHLORIDE | 451W47IQ8X | LOTION / TOPICAL | 0.3 %w/v | ||
| sodium chloride | SODIUM CHLORIDE | 451W47IQ8X | GEL / TOPICAL | 0.18 %w/w | ||
| sodium laureth-3 sulfate | SODIUM LAURETH-3 SULFATE | BPV390UAP0 | SPRAY / TOPICAL | 0.1 %w/w | ||
| FD&C blue no. 1 | FD&C BLUE NO. 1 | H3R47K3TBD | SHAMPOO / TOPICAL | 0.75 %w/w | ||
| sodium benzoate | SODIUM BENZOATE | OJ245FE5EU | SOLUTION / TOPICAL | 0.1 %w/v | ||
| sodium benzoate | SODIUM BENZOATE | OJ245FE5EU | GEL / TOPICAL | 5 mg | ||
| sodium chloride | SODIUM CHLORIDE | 451W47IQ8X | POWDER / TOPICAL | NA | ||
| sodium benzoate | SODIUM BENZOATE | OJ245FE5EU | CREAM / TOPICAL | 0.2 %w/w | ||
| FD&C blue no. 1 | FD&C BLUE NO. 1 | H3R47K3TBD | LIQUID / TOPICAL | NA | ||
| sodium chloride | SODIUM CHLORIDE | 451W47IQ8X | SHAMPOO / TOPICAL | 150 mg | ||
| sodium lauryl sulfate | SODIUM LAURYL SULFATE | 368GB5141J | LOTION / TOPICAL | 111 mg | ||
| sodium chloride | SODIUM CHLORIDE | 451W47IQ8X | POWDER / TOPICAL | NA | ||
| sodium chloride | SODIUM CHLORIDE | 451W47IQ8X | CREAM / TOPICAL | 0.4 %w/w | ||
| FD&C blue no. 1 | FD&C BLUE NO. 1 | H3R47K3TBD | SOLUTION / TOPICAL | 0.01 %w/w | ||
| sodium chloride | SODIUM CHLORIDE | 451W47IQ8X | GEL / TOPICAL | 0.18 %w/w | ||
| sodium lauryl sulfate | SODIUM LAURYL SULFATE | 368GB5141J | SPONGE / TOPICAL | 5 %w/w | ||
| FD&C blue no. 1 | FD&C BLUE NO. 1 | H3R47K3TBD | CREAM / TOPICAL | 0.01 %w/w | ||
| sodium chloride | SODIUM CHLORIDE | 451W47IQ8X | SHAMPOO / TOPICAL | 150 mg | ||
| FD&C blue no. 1 | FD&C BLUE NO. 1 | H3R47K3TBD | LOTION / TOPICAL | NA | ||
| FD&C blue no. 1 | FD&C BLUE NO. 1 | H3R47K3TBD | LIQUID / TOPICAL | NA | ||
| sodium chloride | SODIUM CHLORIDE | 451W47IQ8X | GEL / TOPICAL | 0.18 %w/w | ||
| FD&C yellow no. 5 | FD&C YELLOW NO. 5 | I753WB2F1M | OINTMENT / TOPICAL | 0.01 %w/w |
openFDA label cross-check#
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| Head and Shoulders Green Apple 2in1 | PYRITHIONE ZINC | The Procter & Gamble Manufacturing Company | c036c9a6-6507-4037-b97b-1b015dd950c1 | 2026-03-12 | Warnings | 37000-078-61 37000-078-12 37000-078-40 37000-078-01 37000-078-95 37000-078-70 37000-078-02 37000-078-83 37000-078-11 37000-078-25 37000-078-37 37000-078 37000007861 37000007825 37000007883 37000007840 37000007837 37000007811 37000007895 37000007870 37000007801 37000007812 37000007802 4cda90a8-cfc7-00fd-e063-6294a90aa27d c036c9a6-6507-4037-b97b-1b015dd950c1 |
Reported adverse events (FAERS/openFDA)#
Adverse event summaries are temporarily unavailable. Other product information remains available.