FDA.reportPublic FDA data

Head and Shoulders Clinical Dandruff Defense Dry Scalp Rescue

Manufacturer
The Procter & Gamble Manufacturing Company
Effective date
2025-12-18
Label type
HUMAN OTC DRUG LABEL
Version
4
Source
full-release
Hydrated at
2026-06-01 01:26:56

Label at a glance#

ProductHead and Shoulders Clinical Dandruff Defense Dry Scalp Rescue
Active ingredientPYRITHIONE ZINC
Label structure10 sections

Indications and uses

helps prevent recurrence of flaking and itching associated with dandruff.

Dosage and administration

for best results use at least twice a week or as directed by a doctor. apply to wet hair after shampooing by gently massaging into hair and scalp, rinse well. for maximum dandruff control, use every time you shampoo.

Label contents#

Full prescribing information#

SPL UNCLASSIFIED SECTION

Drug Facts

Active ingredient

OTC - ACTIVE INGREDIENT SECTION

Pyrithione zinc .75%

Purpose

OTC - PURPOSE SECTION

Anti-dandruff

Uses

INDICATIONS & USAGE SECTION

helps prevent recurrence of flaking and itching associated with dandruff.

Warnings

WARNINGS SECTION

For external use only.

When using this product

OTC - WHEN USING SECTION

  • avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water.

Stop use and ask a doctor if

OTC - STOP USE SECTION

  • condition worsens or does not improve after regular use of this product as directed.

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

Keep this and all drugs out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Directions

DOSAGE & ADMINISTRATION SECTION

  • for best results use at least twice a week or as directed by a doctor.
  • apply to wet hair after shampooing by gently massaging into hair and scalp, rinse well.
  • for maximum dandruff control, use every time you shampoo.

Inactive ingredients

INACTIVE INGREDIENT SECTION

Water, stearyl alcohol, cetyl alcohol, stearamidopropyl dimethylamine, glutamic acid, dimethicone, fragrance, phenoxyethanol, benzyl alcohol, sodium chloride, citric acid, honey extract,methylchloroisothiazolinone, methylisothiazolinone.

Questions (or comments)?

OTC - QUESTIONS SECTION

1-800-723-9569

SPL UNCLASSIFIED SECTION

Dist. by PROCTER & GAMBLE,
CINCINNATI, OH 45202

PRINCIPAL DISPLAY PANEL - TUBE LABEL

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

head &

shoulders ®
pyrithione zinc dandruff conditioner

Clinical

Dandruff

Defense

Dry Scalp

Rescue

with Manuka Honey

100% DANDRUFF PROTECTION SATISFACTION GUARANTEED*

9.1 FL OZ (270 mL)

HSHS

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYSPL version
1441563head & shoulders Damage Treatment 0.75 % Medicated ShampooPSN4
1441558zinc pyrithione 0.75 % Medicated ShampooPSN4
1441563zinc pyrithione 7.5 MG/ML Medicated Shampoo [Head & Shoulders Damage Treatment]SBD4
1441558zinc pyrithione 7.5 MG/ML Medicated ShampooSCD4
1441563Head & Shoulders Damage Treatment 0.75 % Medicated ShampooSY4
1441563Head & Shoulders Damage Treatment 7.5 MG/ML Medicated ShampooSY4
1441558zinc pyrithione 0.75 % Medicated ShampooSY4

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
0ca1d589-929b-4b33-bc5b-1d84abdafa6aProduct name120150324
fc363c46-397b-4476-ac0f-70e43e8e4592Product name120150324

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDCEffectiveActionDocumentIndexing SPLRelated label
69423-568-272023-05-08C16284748780-1f386c649-c48c-0266-e053-dadaa90a7c1aHead and Shoulders ® Clinical Dandruff Defense Dry Scalp Rescue
69423-568-272023-01-30C16284748780-1f386c649-c48c-0266-e053-dadaa90a7c1aHead and Shoulders ® Clinical Dandruff Defense Dry Scalp Rescue

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
69423-568-27Head and Shoulders Clinical Dandruff Defense Dry Scalp Rescue270 mL in 1 TUBELOTION2704

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 15 matching rows.

NDC Codes#

Product NDC, Package NDC table
Product NDCPackage NDC
69423-56869423-568-27

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 14 matching rows.

Name, UNII, Kind table
NameUNIIKind
METHYLCHLOROISOTHIAZOLINONEDEL7T5QRPNIACT
METHYLISOTHIAZOLINONE229D0E1QFAIACT
PYRITHIONE ZINCR953O2RHZ5ACTIB
STEARAMIDOPROPYL DIMETHYLAMINEK7VEI00UFRIACT
GLUTAMIC ACID3KX376GY7LIACT
PHENOXYETHANOLHIE492ZZ3TIACT
BENZYL ALCOHOLLKG8494WBHIACT
CITRIC ACID MONOHYDRATE2968PHW8QPIACT
HONEYY9H1V576FHIACT
SODIUM CHLORIDE451W47IQ8XIACT
STEARYL ALCOHOL2KR89I4H1YIACT
CETYL ALCOHOL936JST6JCNIACT
WATER059QF0KO0RIACT
DIMETHICONE92RU3N3Y1OIACT

Source Document#

Source XML

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Head and Shoulders Clinical Dry Scalp Rescue KitPYRITHIONE ZINCThe Procter & Gamble Manufacturing Company1a3ac96a-04ec-6865-e063-6394a90a9fb82025-12-31WarningsExact identifier
ndc (package): 69423-568-27
ndc11 (package): 69423056827
Head and Shoulders Clinical Dandruff Defense Dry Scalp RescuePYRITHIONE ZINCThe Procter & Gamble Manufacturing Companyc7bc3942-6943-2ea5-e053-2a95a90a42a92025-12-18WarningsExact identifier
ndc (package): 69423-568-27
ndc (product): 69423-568
ndc11 (package): 69423056827
spl id: 46417fb5-59f1-15d4-e063-6394a90a10b2
spl set id: c7bc3942-6943-2ea5-e053-2a95a90a42a9

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.