ActivOn Ultra Strength Arthritis

Manufacturer: Family First Pharmaceuticals, Inc. | RNA Pharma, LLC
Effective date: 2015-04-22
Label type: HUMAN OTC DRUG LABEL
Version: 3
Source: full-release
Hydrated at: 2026-05-31 22:42:21

Label at a glance#

ProductActivOn Ultra Strength Arthritis

Active ingredientMenthol, unspecified form, Histamine Dihydrochloride

Label structure10 sections

Indications and uses

For the temporary relief of minor aches and pains of muscles and joints associated with simple backache arthritis strains bruises sprains

Dosage and administration

adults and children 12 years of age and older: apply to affected area not more than 3 to 4 times daily. children under 12 years of age: ask a doctor

Storage and handling

Keep away from heat. Store between 15° and 30° C (59° and 86° F).

Contacts and useful links#

PhoneLabel contact1-800-379-8870

Label contents#

Full prescribing information#

SPL UNCLASSIFIED SECTION

Drug Facts

OTC - ACTIVE INGREDIENT SECTION

OTC - PURPOSE SECTION

Active Ingredient	Purpose
Histamine Dihydrochloride 0.028%	Topical Analgesic
Menthol 4.574%	Topical Analgesic

Uses

INDICATIONS & USAGE SECTION

For the temporary relief of minor aches and pains of muscles and joints associated with
- simple backache
- arthritis
- strains
- bruises
- sprains

Warnings

WARNINGS SECTION

For external use only.

Do not use

OTC - DO NOT USE SECTION

otherwise than as directed
if you are allergic to any ingredient in this product
on a child 12 years of age with arthritis-like conditions
with a heating pad

When using this product

OTC - WHEN USING SECTION

avoid contact with eyes, wounds, mucous membranes, broken or irritated skin
do not share this product with anyone
do not bandage tightly

Stop use and ask a doctor if

OTC - STOP USE SECTION

condition worsens, or if symptoms persist for more than 7 days or clear up and occur again within a few days
skin redness or excessive irritation of the skin develops

OTC - PREGNANCY OR BREAST FEEDING SECTION

If pregnant or breast-feeding, ask a health professional before use.

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

Keep out of the reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Directions

DOSAGE & ADMINISTRATION SECTION

adults and children 12 years of age and older: apply to affected area not more than 3 to 4 times daily.
children under 12 years of age: ask a doctor

Other information

STORAGE AND HANDLING SECTION

Keep away from heat. Store between 15° and 30° C (59° and 86° F).

Inactive Ingredients

INACTIVE INGREDIENT SECTION

diazoldinyl urea, ethyl alcohol, iodopropynyl butlylcarbamate, menthyl lactate, propylene glycol, sodium stearate, steareth-21, tetrasodium EDTA, triethenolamine, water

Questions ?

OTC - QUESTIONS SECTION

call 1-800-379-8870, Weekdays 9AM to 5PM EST or visit us online at activ-on.com

SPL UNCLASSIFIED SECTION

Dist. by Family First Pharmaceuticals, Inc., Reno, NV 89502

PRINCIPAL DISPLAY PANEL - 57 g Carton

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

NEW
STRONGEST
ACTIV_ON ^® ARTHRITIS

ACTIV_ON ^®
Topical Analgesic

ULTRA
STRENGTH
ARTHRITIS

Powerful Pain Relief
for Arthritis & Joint & Muscle Pain

No-Mess

NDC 51068-501-01
NET WT 2 OZ (57 g)

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	SPL version
1148636	ActivOn Ultra Strength Arthritis (histamine dihydrochloride 0.028 % / menthol 4.574 % ) Topical Cream	PSN	3
1148634	histamine dihydrochloride 0.028 % / menthol 4.57 % Topical Cream	PSN	3
1148636	histamine dihydrochloride 0.28 MG/ML / menthol 45.7 MG/ML Topical Cream [ActivOn Arthritis]	SBD	3
1148634	histamine dihydrochloride 0.28 MG/ML / menthol 45.7 MG/ML Topical Cream	SCD	3
1148636	ActivOn Ultra Strength Arthritis (histamine dihydrochloride 0.028 % / menthol 4.574 % ) Topical Cream	SY	3
1148634	histamine dihydrochloride 0.028 % / menthol 4.574 % Topical Cream	SY	3

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDC	Effective	Action	Document	Indexing SPL	Related label
51068-501-01	2020-01-31	C162847	48780-1	9d75b9d0-19cc-f424-e053-dadaa90a57ce	ACTIV ON ® Topical Analgesic ULTRA STRENGTH ARTHRITIS

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
51068-501-01	ActivOn Ultra Strength Arthritis	1 in 1 CARTON	STICK	1		3
51068-501-01	ActivOn Ultra Strength Arthritis	57 g in 1 CANISTER	STICK	57		3

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
51068-501	ACTIVON ULTRA STRENGTH ARTHRITIS (MENTHOL AND HISTAMINE DIHYDROCHLORIDE) STICK [FAMILY FIRST PHARMACEUTICALS, INC.]	3	Legacy NDC, 2 package rows	20150423_d123deae-d9ef-45ce-81ed-2d79384b1298.zip

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	SPL version
Histamine Dihydrochloride	ACTIVE INGREDIENT	3POA0Q644U	3
Menthol, unspecified form	ACTIVE INGREDIENT	L7T10EIP3A	3
Histamine	ACTIVE MOIETY	820484N8I3	3
Menthol, unspecified form	ACTIVE MOIETY	L7T10EIP3A	3
alcohol	INACTIVE INGREDIENT	3K9958V90M	3
diazolidinyl urea	INACTIVE INGREDIENT	H5RIZ3MPW4	3
Edetate Sodium	INACTIVE INGREDIENT	MP1J8420LU	3
iodopropynyl butylcarbamate	INACTIVE INGREDIENT	603P14DHEB	3
menthyl lactate, (-)-	INACTIVE INGREDIENT	2BF9E65L7I	3
propylene glycol	INACTIVE INGREDIENT	6DC9Q167V3	3
sodium stearate	INACTIVE INGREDIENT	QU7E2XA9TG	3
steareth-21	INACTIVE INGREDIENT	53J3F32P58	3
trolamine	INACTIVE INGREDIENT	9O3K93S3TK	3
water	INACTIVE INGREDIENT	059QF0KO0R	3

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 15 matching rows.

ActivOn Ultra Strength Arthritis
Menthol and Histamine Dihydrochloride
Menthol, unspecified form
Histamine Dihydrochloride
Histamine
diazolidinyl urea
alcohol
iodopropynyl butylcarbamate
menthyl lactate, (-)-
propylene glycol
sodium stearate
steareth-21
Edetate Sodium
trolamine
water

NDC Codes#

Product NDC, Package NDC table
Product NDC	Package NDC
51068-501	51068-501-01

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 12 matching rows.

Name, UNII, Kind table
Name	UNII	Kind
Menthol, unspecified form	L7T10EIP3A	ACTIB
Histamine Dihydrochloride	3POA0Q644U	ACTIB
diazolidinyl urea	H5RIZ3MPW4	IACT
alcohol	3K9958V90M	IACT
iodopropynyl butylcarbamate	603P14DHEB	IACT
menthyl lactate, (-)-	2BF9E65L7I	IACT
propylene glycol	6DC9Q167V3	IACT
sodium stearate	QU7E2XA9TG	IACT
steareth-21	53J3F32P58	IACT
Edetate Sodium	MP1J8420LU	IACT
trolamine	9O3K93S3TK	IACT
water	059QF0KO0R	IACT

Source Document#

Source XML

Inactive ingredient matches#

Inactive Ingredient Database values describe FDA-listed use contexts. The match method and ambiguity count are shown because ingredient names, routes, and dosage forms are not always unique. Browse recovered IID releases and source provenance.

Inactive ingredient links page 1 of 4 · 182 matching rows.

DailyMed ingredient, IID ingredient, UNII table
DailyMed ingredient	IID ingredient	UNII	Dosage form / route	Potency	Maximum daily exposure	Match
alcohol	ALCOHOL	3K9958V90M	SOLUTION / INTRAVESICAL		7892 mg	Exact identifier — unii candidate 59 equally ranked IID candidates
trolamine	TROLAMINE	9O3K93S3TK	SOLUTION / TOPICAL	NA		Exact identifier — unii candidate 22 equally ranked IID candidates
alcohol	ALCOHOL	3K9958V90M	GEL / DENTAL	1.8 %w/w		Exact identifier — unii candidate 59 equally ranked IID candidates
alcohol	ALCOHOL	3K9958V90M	SPRAY / TRANSDERMAL	90 %w/v		Exact identifier — unii candidate 59 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	SOLUTION / OPHTHALMIC	1 %w/v		Exact identifier — unii candidate 81 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	FILM, EXTENDED RELEASE / TRANSDERMAL	58.13 mg		Exact identifier — unii candidate 81 equally ranked IID candidates
trolamine	TROLAMINE	9O3K93S3TK	GEL / TRANSDERMAL		6 mg	Exact identifier — unii candidate 22 equally ranked IID candidates
alcohol	ALCOHOL	3K9958V90M	INJECTION, SOLUTION / INTRAVENOUS		6405 mg	Exact identifier — unii candidate 59 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	CAPSULE, DELAYED RELEASE / ORAL	1.7 mg		Exact identifier — unii candidate 81 equally ranked IID candidates
Edetate Sodium	EDETATE SODIUM	MP1J8420LU	SPONGE / TOPICAL	0.14 %w/w		Exact identifier — unii candidate 12 equally ranked IID candidates
trolamine	TROLAMINE	9O3K93S3TK	CREAM / TOPICAL	1 %w/w		Exact identifier — unii candidate 22 equally ranked IID candidates
steareth-21	STEARETH-21	53J3F32P58	LOTION / TOPICAL	3 %w/w		Exact identifier — unii candidate 2 equally ranked IID candidates
alcohol	ALCOHOL	3K9958V90M	AEROSOL, SPRAY / TOPICAL		561 mg	Exact identifier — unii candidate 59 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	SOLUTION / INTRAVENOUS	5 %w/v		Exact identifier — unii candidate 81 equally ranked IID candidates
trolamine	TROLAMINE	9O3K93S3TK	EMULSION / TOPICAL	0.5 %w/w		Exact identifier — unii candidate 22 equally ranked IID candidates
Edetate Sodium	EDETATE SODIUM	MP1J8420LU	SOLUTION / OPHTHALMIC	0.1 %w/v		Exact identifier — unii candidate 12 equally ranked IID candidates
trolamine	TROLAMINE	9O3K93S3TK	SOLUTION / NASAL	NA		Exact identifier — unii candidate 22 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	EMULSION / TOPICAL	8 %w/w		Exact identifier — unii candidate 81 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	LIQUID / RESPIRATORY (INHALATION)	10 %w/w		Exact identifier — unii candidate 81 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	JELLY / TOPICAL	20 %w/w		Exact identifier — unii candidate 81 equally ranked IID candidates
trolamine	TROLAMINE	9O3K93S3TK	GEL, METERED / TRANSDERMAL		14 mg	Exact identifier — unii candidate 22 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	SUSPENSION / ORAL		27120 mg	Exact identifier — unii candidate 81 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	SOLUTION / DENTAL	2 %w/w		Exact identifier — unii candidate 81 equally ranked IID candidates
sodium stearate	SODIUM STEARATE	QU7E2XA9TG	TABLET, DELAYED RELEASE / ORAL		10 mg	Exact identifier — unii candidate 3 equally ranked IID candidates
alcohol	ALCOHOL	3K9958V90M	DROPS / ORAL	210 mg/1ml		Exact identifier — unii candidate 59 equally ranked IID candidates
trolamine	TROLAMINE	9O3K93S3TK	DROPS / NASAL	NA		Exact identifier — unii candidate 22 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	CREAM / VAGINAL		1225 mg	Exact identifier — unii candidate 81 equally ranked IID candidates
alcohol	ALCOHOL	3K9958V90M	MOUTHWASH / BUCCAL	200 mg/1ml		Exact identifier — unii candidate 59 equally ranked IID candidates
alcohol	ALCOHOL	3K9958V90M	TABLET, DELAYED RELEASE / ORAL	NA		Exact identifier — unii candidate 59 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	SHAMPOO / TOPICAL	8 %w/w		Exact identifier — unii candidate 81 equally ranked IID candidates
alcohol	ALCOHOL	3K9958V90M	SWAB / TOPICAL		2250 mg	Exact identifier — unii candidate 59 equally ranked IID candidates
diazolidinyl urea	DIAZOLIDINYL UREA	H5RIZ3MPW4	CREAM / TOPICAL		29 mg	Exact identifier — unii candidate 3 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	AEROSOL, FOAM / RECTAL		1214 mg	Exact identifier — unii candidate 81 equally ranked IID candidates
Edetate Sodium	EDETATE SODIUM	MP1J8420LU	INJECTION / INTRAMUSCULAR	0.01 %w/v		Exact identifier — unii candidate 12 equally ranked IID candidates
alcohol	ALCOHOL	3K9958V90M	SOLUTION, CONCENTRATE / INTRAVENOUS		4000 mg	Exact identifier — unii candidate 59 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	CAPSULE, COATED / ORAL	25 mg		Exact identifier — unii candidate 81 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	TABLET, FILM COATED, EXTENDED RELEASE / ORAL		19 mg	Exact identifier — unii candidate 81 equally ranked IID candidates
trolamine	TROLAMINE	9O3K93S3TK	LIQUID / TOPICAL	NA		Exact identifier — unii candidate 22 equally ranked IID candidates
alcohol	ALCOHOL	3K9958V90M	SOLUTION / TRANSDERMAL	49.37 %w/v		Exact identifier — unii candidate 59 equally ranked IID candidates
alcohol	ALCOHOL	3K9958V90M	SOLUTION / NASAL	10 mg/1ml		Exact identifier — unii candidate 59 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	SOLUTION, CONCENTRATE / INTRAVENOUS	50.33 %w/v		Exact identifier — unii candidate 81 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	CONCENTRATE / ORAL		7000 mg	Exact identifier — unii candidate 81 equally ranked IID candidates
Edetate Sodium	EDETATE SODIUM	MP1J8420LU	SOAP / TOPICAL	0.12 %w/w		Exact identifier — unii candidate 12 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	CREAM, AUGMENTED / TOPICAL	8 %w/w		Exact identifier — unii candidate 81 equally ranked IID candidates
Edetate Sodium	EDETATE SODIUM	MP1J8420LU	LOTION / TOPICAL	0.17 %w/w		Exact identifier — unii candidate 12 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	SOLUTION, CONCENTRATE / ORAL		2590 mg	Exact identifier — unii candidate 81 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	INJECTION, SOLUTION / SUBCUTANEOUS	1.4 %w/v		Exact identifier — unii candidate 81 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	OINTMENT, AUGMENTED / TOPICAL		714 mg	Exact identifier — unii candidate 81 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	SOLUTION/ DROPS / AURICULAR (OTIC)	ADJ PH		Exact identifier — unii candidate 81 equally ranked IID candidates
alcohol	ALCOHOL	3K9958V90M	AEROSOL, METERED / NASAL	70 mg		Exact identifier — unii candidate 59 equally ranked IID candidates
alcohol	ALCOHOL	3K9958V90M	POWDER, FOR SOLUTION / TOPICAL	40 %w/w		Exact identifier — unii candidate 59 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	INJECTION, SOLUTION / INTRAVENOUS		4000 mg	Exact identifier — unii candidate 81 equally ranked IID candidates
alcohol	ALCOHOL	3K9958V90M	INJECTION / SUBCUTANEOUS		149 mg	Exact identifier — unii candidate 59 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	SUSPENSION, EXTENDED RELEASE / ORAL		1000 mg	Exact identifier — unii candidate 81 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	GEL, METERED / TOPICAL		1225 mg	Exact identifier — unii candidate 81 equally ranked IID candidates
diazolidinyl urea	DIAZOLIDINYL UREA	H5RIZ3MPW4	OINTMENT / TOPICAL	0.1 %w/w		Exact identifier — unii candidate 3 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	SUSPENSION / OPHTHALMIC	0.6 %w/v		Exact identifier — unii candidate 81 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	ELIXIR / ORAL		9306 mg	Exact identifier — unii candidate 81 equally ranked IID candidates
propylene glycol	PROPYLENE GLYCOL	6DC9Q167V3	SPRAY, METERED / NASAL		240 mg	Exact identifier — unii candidate 81 equally ranked IID candidates
alcohol	ALCOHOL	3K9958V90M	AEROSOL, FOAM / TOPICAL		4504 mg	Exact identifier — unii candidate 59 equally ranked IID candidates

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
6a97a677-5c25-4d3a-9593-3191f6a981bd			d123deae-d9ef-45ce-81ed-2d79384b1298	2015-04-22	Warnings	Exact identifier spl id: 6a97a677-5c25-4d3a-9593-3191f6a981bd spl set id: d123deae-d9ef-45ce-81ed-2d79384b1298

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.