Directions ■ drink plenty of clear fluids to help prevent dehydration caused by diarrhea ■ find right dose on chart. If possible, use weight to dose; otherwise use age. adults and children 12 years and over 2 caplets after the first loose stool; 1 caplet after each subsequent loose stool; but no more than 4 caplets in 24 hour children 9 - 11 years (60 - 95 lbs) 1 caplet after the first loose stool; 1/2 caplet afte...
Loperamide HCl, USP 2 mg
Anti-diarrheal
Controls symptoms of diarrhea, including Travelers’ Diarrhea
Allergy alert:Do not use if you have ever had a rash or other allergic reaction to Loperamide HCl.
Heart alert:Taking more than directed can cause serious heart problems or death.
Do not useif you have bloody or black stool
Ask a doctor before use if you have
■ fever
■ mucus in the stool
■ a history of liver disease
■ a history of abnormal heart rhythm
Ask a doctor or pharmacist before use if you aretaking a prescription
drug. Loperamide may interact with certain prescription drugs.
When using this producttiredness, drowsiness or dizziness may occur. Be careful when driving or operating machinery.
Stop use and ask a doctor if
■ symptoms get worse
■ diarrhea lasts for more than 2 days
■ you get abdominal swelling or bulging. These may be signs of a serious condition.
If pregnant or breast-feeding,ask a health professional before use.
Keep out of reach of children.In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222)
Directions
■
drink plenty of clear fluids to help prevent dehydration caused by diarrhea
■ find right dose on chart. If possible, use weight to dose; otherwise use age.
| adults and children 12 years and over | 2 caplets after the first loose stool; 1 caplet after each subsequent loose stool;
|
children 9 - 11 years (60 - 95 lbs) | 1 caplet after the first loose stool; 1/2 caplet after each subsequent loose stool; but no more than 3 caplets in 24 hours |
children 6 - 8 years (48 - 59 lbs) | 1 caplet after the first loose stool; 1/2 caplet after each subsequent loose stool;
|
children 2 - 5 years (34 - 47 lbs) | ask a doctor |
children under 2 (up to 33 lbs) | do not use |
Other information
■ store between 68-77°F (20-25°C)
Inactive ingredients
anhydrous lactose, croscarmellose sodium, crospovidone, D&C Yellow
no. 10 aluminum lake, FD&C Blue no. 1 aluminum lake, hydrogenated
vegetable oil, magnesium stearate, powdered cellulose, pregelatinized
starch
Questions or comments?
call toll-free
1-877-507-6516 (M-F 8AM - 4:30PM CST)
CONTROLS THE SYMPTOMS OF DIARRHEA
Compare to the active ingredient in
Imodium® A-D*
CIRCLE K ™
antidiarrheal
Loperamide HCI
Tablets, USP
2 mg
[caplet image]
actual size
4 caplets**(2 per pouch)
| Class | Version | Type | Effective |
|---|---|---|---|
| LOPERAMIDE Pharmacologic Class Indexing | 2 | Indexing - Pharmacologic Class | 20180813 |
| Product concept | Relation | Version | Effective |
|---|---|---|---|
| 10f838ef-a72b-645d-80f8-e2255205c3b1 | Product name | 6 | 20240805 |
| Package NDC | Product | Description | Form | Quantity | Strength | SPL version |
|---|---|---|---|---|---|---|
| 66715-5529-2 | Anti-Diarrheal, Circle K | 2 in 1 POUCH | TABLET | 2 | 3 | |
| 66715-5529-2 | Anti-Diarrheal, Circle K | 2 in 1 CARTON | TABLET | 2 | 3 |
| NDC | Dashboard title | SPL version | Validation | Dashboard ZIP |
|---|---|---|---|---|
| 66715-5529 | ANTI-DIARRHEAL, CIRCLE K (LOPERAMIDE HCL TABLET) TABLET [LIL' DRUG STORE PRODUCTS, INC.] | 3 | Current NDC, Legacy NDC, 2 package rows | 20250101_d3aaad65-f4cd-5eb0-e053-2995a90ade84.zip |
Every source-derived product name is available through these pages.
| Product NDC | Package NDC |
|---|---|
| 66715-5529 | 66715-5529-2 |
Every source-derived ingredient row is available through these pages.
| Name | UNII | Kind |
|---|---|---|
| CROSCARMELLOSE SODIUM | M28OL1HH48 | IACT |
| D&C YELLOW NO. 10 | 35SW5USQ3G | IACT |
| CROSPOVIDONE (15 MPA.S AT 5%) | 68401960MK | IACT |
| FD&C BLUE NO. 1 | H3R47K3TBD | IACT |
| HYDROGENATED COTTONSEED OIL | Z82Y2C65EA | IACT |
| ANHYDROUS LACTOSE | 3SY5LH9PMK | IACT |
| MAGNESIUM STEARATE | 70097M6I30 | IACT |
| POWDERED CELLULOSE | SMD1X3XO9M | IACT |
| STARCH, CORN | O8232NY3SJ | IACT |
| LOPERAMIDE HYDROCHLORIDE | 77TI35393C | ACTIB |
All distinct exact application/product contexts derived from this label’s complete NDC list are paginated below.
| Application-product | Trade name | Ingredient | Strength | Dosage form / route | TE codes | RLD / RS | Approval date |
|---|---|---|---|---|---|---|---|
| A074091-001 | LOPERAMIDE HYDROCHLORIDE | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 |
Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.
| Captured | Edition | Application-product | Trade name | Strength | Dosage form / route | Product TE source text | RLD / RS | Approval date | Source SHA-256 |
|---|---|---|---|---|---|---|---|---|---|
| 2026-09-14 22:38:34 | 2026-08 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 84e616aacf4f… | ||
| 2026-08-18 06:07:40 | 2026-07 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | caaa826d4ba7… | ||
| 2026-02-19 14:30 UTC | 2026-02 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 011fe1cb6892… | ||
| 2025-12-14 10:44 UTC · 2 captures of this ZIP | 2025-12 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 31067a03dcf5… | ||
| 2025-08-23 18:47 UTC | 2025-08 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 6a471c1ec25d… | ||
| 2025-03-22 03:13 UTC · 3 captures of this ZIP | 2025-03 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | fd3edfee7708… | ||
| 2025-02-26 10:13 UTC · 3 captures of this ZIP | 2025-02 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | b8a1b40f171c… | ||
| 2025-01-19 17:59 UTC · 7 captures of this ZIP | 2025-01 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 03ed91905a0d… | ||
| 2024-12-13 21:23 UTC · 2 captures of this ZIP | 2024-12 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 2680178bc6a6… | ||
| 2024-09-14 05:58 UTC · 2 captures of this ZIP | 2024-09 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 5bbf6a4d5a75… | ||
| 2024-11-08 22:44 UTC · 3 captures of this ZIP | 2024-11 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | d8e5a09893c0… | ||
| 2024-10-29 15:01 UTC | 2024-10 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | d06236e962d9… | ||
| 2024-08-13 05:28 UTC · 3 captures of this ZIP | 2024-08 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 79d66fd596c7… | ||
| 2024-07-13 05:37 UTC · 2 captures of this ZIP | 2024-07 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 301d65b070ca… | ||
| 2024-06-18 03:08 UTC · 5 captures of this ZIP | 2024-06 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 1e350fbaab3a… | ||
| 2024-05-31 18:47 UTC | 2024-05 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 8072bd15b7f6… | ||
| 2022-06-29 02:47 UTC · 2 captures of this ZIP | 2022-06 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 5c6f7cd8ea54… | ||
| 2022-04-08 23:34 UTC | 2022-04 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 5d02ea3f76ae… | ||
| 2022-04-04 05:41 UTC | 2022-04 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 4b0b4de00fa7… | ||
| 2019-12-13 00:20 UTC | 2019-12 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 74a2ff9319b5… | ||
| 2022-03-09 01:35 UTC | 2022-03 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | bb7c543d1eb4… | ||
| 2021-12-28 21:50 UTC | 2021-12 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 782e0a99824c… | ||
| 2021-05-05 16:15 UTC · 3 captures of this ZIP | 2021-05 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 87673890dc5c… | ||
| 2021-03-12 10:30 UTC | 2021-03 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 5aa47cf7b7d7… | ||
| 2020-12-22 03:56 UTC | 2020-12 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 8869cabd3fbd… | ||
| 2020-11-12 02:37 UTC | 2020-11 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | c0c555d07b60… | ||
| 2019-12-14 00:12 UTC | 2019-12 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 3f01610625f2… | ||
| 2019-09-15 20:21 UTC | 2019-09 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | b00525d2431f… | ||
| 2019-07-19 19:46 UTC | 2019-07 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | ea99ee380514… | ||
| 2024-03-16 18:09 UTC · 4 captures of this ZIP | 2024-03 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 6a51e52b5d6a… | ||
| 2024-02-18 07:12 UTC | 2024-02 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 1c564ffb4f44… | ||
| 2023-12-20 04:57 UTC | 2023-12 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | ea1830bbd6c7… | ||
| 2023-11-28 05:40 UTC · 2 captures of this ZIP | 2023-11 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | a72a2bbeb626… | ||
| 2023-10-25 00:34 UTC · 2 captures of this ZIP | 2023-10 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 9b2671bbb829… | ||
| 2023-07-15 15:27 UTC · 2 captures of this ZIP | 2023-07 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | a67488948f0b… | ||
| 2023-06-13 01:57 UTC · 3 captures of this ZIP | 2023-06 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 3f0d92c62455… | ||
| 2023-05-13 08:27 UTC | 2023-05 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 053a50430f4f… | ||
| 2023-01-26 05:58 UTC | 2023-01 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 3bdfa0b2c4d7… | ||
| 2022-11-12 20:34 UTC · 5 captures of this ZIP | 2022-11 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | 3a93d1ddd44b… | ||
| 2022-10-28 04:53 UTC | 2022-10 | A074091-001 | LOPERAMIDE HYDROCHLORIDE | 2MG | TABLET / ORAL | 1992-12-10 | f41ea6bd6efb… |
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| Anti-Diarrheal, Circle K | LOPERAMIDE HCL TABLET | Lil' Drug Store Products, Inc. | d3aaad65-f4cd-5eb0-e053-2995a90ade84 | 2024-12-29 | Warnings | 66715-5529-2 66715-5529 66715552902 2a764bad-d1df-ddcc-e063-6294a90adea4 d3aaad65-f4cd-5eb0-e053-2995a90ade84 |
Adverse event summaries are temporarily unavailable. Other product information remains available.