Crest Pro-Health

Manufacturer: The Procter & Gamble Manufacturing Company
Effective date: 2026-01-08
Label type: HUMAN OTC DRUG LABEL
Version: 8
Source: monthly-update
Hydrated at: 2026-06-03 17:51:59

Label at a glance#

ProductCrest Pro-Health Advantage

Active ingredientCETYLPYRIDINIUM CHLORIDE

Label structure10 sections

Indications and uses

helps prevent and reduce plaque and gingivitis helps control plaque bacteria that contribute to the development of gingivitis and bleeding gums

Dosage and administration

use after your normal brushing and flossing routine; rinse toothpaste from mouth prior to use adults and children 6 yrs. & older: Rinse for 30 seconds with 20 mL (4 teaspoonfuls) twice a day do not swallow children 6 years to under 12 years of age: supervise use children under 6 years of age: do not use

Label contents#

Full prescribing information#

SPL UNCLASSIFIED SECTION

Drug Facts

Active ingredient

OTC - ACTIVE INGREDIENT SECTION

Cetylpyridinium chloride 0.07%

Purpose

OTC - PURPOSE SECTION

Antigingivitis/antiplaque

Uses

INDICATIONS & USAGE SECTION

helps prevent and reduce plaque and gingivitis
helps control plaque bacteria that contribute to the development of gingivitis and bleeding gums

Warnings

WARNINGS SECTION

OTC - ASK DOCTOR SECTION

Ask a dentist if symptoms persist or condition worsens after regular use.

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

Keep out of reach of children under 6 years of age. If more than used for rinsing is accidentally swallowed, get medical help or contact a Poison Control Center right away.

Directions

DOSAGE & ADMINISTRATION SECTION

use after your normal brushing and flossing routine; rinse toothpaste from mouth prior to use
adults and children 6 yrs. & older: Rinse for 30 seconds with 20 mL (4 teaspoonfuls) twice a day
- do not swallow
- children 6 years to under 12 years of age: supervise use
children under 6 years of age: do not use

Inactive ingredients

INACTIVE INGREDIENT SECTION

water, glycerin, flavor, zinc lactate, methylparaben, sodium saccharin, sucralose, propylparaben, poloxamer 407, blue 1

Questions?

OTC - QUESTIONS SECTION

1–800–285–9139

SPL UNCLASSIFIED SECTION

DISTR. BY PROCTER & GAMBLE,
CINCINNATI, OH 45202

Crest Pro Health Advantage Rinse 1L

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

ALCOHOL FREE

Crest ®
PRO-HEALTH™

ADVANTAGE
CPC ANTIGINGIVITIS/ANTIPLAQUE ORAL MOUTHWASH

99% GERM KILL

AND A HEALTHIER MOUTH*

MULTI-PROTECTION SMOOTH MINT

REDUCES PLAUE BACTERIA

HELPS PREVENT GINGIVITIS

FRESHENS BREATH

1 L (33.8 FL OZ)

Crest Pro Health Advantage Rinse

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	SPL version
1100924	cetylpyridinium chloride 0.07 % Oral Rinse	PSN	8
1251371	Crest Pro-Health 0.07 % Oral Rinse	PSN	8
1251371	cetylpyridinium chloride 0.7 MG/ML Mouthwash [Crest Mouthwash]	SBD	8
1100924	cetylpyridinium chloride 0.7 MG/ML Mouthwash	SCD	8
1100924	cetylpyridinium chloride 0.07 % Oral Rinse	SY	8
1251371	Crest 0.07 % Mouthwash	SY	8

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
69423-893-31	Crest Pro-HealthAdvantage	1000 mL in 1 BOTTLE	RINSE	1000	8
69423-893-31	Crest Pro-HealthAdvantage	3 in 1 CELLO PACK	RINSE	3	8
69423-893-33	Crest Pro-HealthAdvantage	1000 mL in 1 BOTTLE, PLASTIC	RINSE	1000	8

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 12 matching rows.

Crest Pro-Health Advantage
Cetylpyridinium chloride
PROPYLPARABEN
SUCRALOSE
GLYCERIN
ZINC LACTATE
METHYLPARABEN
SACCHARIN SODIUM
POLOXAMER 407
WATER
FD&C BLUE NO. 1
CETYLPYRIDINIUM

NDC Codes#

Product NDC, Package NDC table
Product NDC	Package NDC
69423-893	69423-893-33, 69423-893-31

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 10 matching rows.

Name, UNII, Kind table
Name	UNII	Kind
PROPYLPARABEN	Z8IX2SC1OH	IACT
SUCRALOSE	96K6UQ3ZD4	IACT
GLYCERIN	PDC6A3C0OX	IACT
ZINC LACTATE	2GXR25858Y	IACT
METHYLPARABEN	A2I8C7HI9T	IACT
SACCHARIN SODIUM	SB8ZUX40TY	IACT
POLOXAMER 407	TUF2IVW3M2	IACT
WATER	059QF0KO0R	IACT
FD&C BLUE NO. 1	H3R47K3TBD	IACT
CETYLPYRIDINIUM CHLORIDE	D9OM4SK49P	ACTIB

Source Document#

Source XML

Older Hydrated Versions#

Version, Effective date, Source table
Version	Effective date	Source	Hydrated
7	2025-12-11	full-release	2026-06-01 01:22:24

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Crest Pro-Health Advantage	CETYLPYRIDINIUM CHLORIDE	The Procter & Gamble Manufacturing Company	ddcd56fe-25d6-8195-e053-2a95a90a575a	2026-01-08	Warnings	Exact identifier ndc (package): 69423-893-33 ndc (package): 69423-893-31 ndc (product): 69423-893 ndc11 (package): 69423089331 ndc11 (package): 69423089333 spl id: 47e4b20c-da2c-c123-e063-6294a90aaf0b spl set id: ddcd56fe-25d6-8195-e053-2a95a90a575a

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.