Nioxin Scalp Optimizing Cleanser

Manufacturer: The Wella Corporation | Coty US LLC | Thibiant International, Inc.
Effective date: 2020-02-11
Label type: HUMAN OTC DRUG LABEL
Version: 4
Source: legacy-cache
Hydrated at: 2026-08-01 23:41:19

Label at a glance#

ProductNioxin Scalp Optimizing Cleanser Advanced Thinning

Active ingredientPYRITHIONE ZINC

Label structure10 sections

Indications and uses

helps prevent recurrence of flaking and itching associated with dandruff.

Dosage and administration

for best results use at least twice a week or as directed by a doctor. for maximum dandruff control, use every time you shampoo. shake before use. wet hair, massage onto scalp, rinse, repeat if desired.

Contacts and useful links#

PhoneLabel contact1-800-935-5273

Label contents#

Full prescribing information#

SPL UNCLASSIFIED SECTION

Drug Facts

Active ingredient

OTC - ACTIVE INGREDIENT SECTION

Pyrithione zinc 1%

Purpose

OTC - PURPOSE SECTION

Anti-dandruff

Uses

INDICATIONS & USAGE SECTION

helps prevent recurrence of flaking and itching associated with dandruff.

Warnings

WARNINGS SECTION

For external use only.

When using this product

OTC - WHEN USING SECTION

avoid contact with eyes. If contact occurs, rinse eyes thoroughly with water.

Stop use and ask a doctor if

OTC - STOP USE SECTION

condition worsens or does not improve after regular use of this product as directed.

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

Keep this and all drugs out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Directions

DOSAGE & ADMINISTRATION SECTION

for best results use at least twice a week or as directed by a doctor.
for maximum dandruff control, use every time you shampoo.
shake before use.
wet hair, massage onto scalp, rinse, repeat if desired.

Inactive ingredients

INACTIVE INGREDIENT SECTION

water, sodium laureth sulfate, sodium lauryl sulfate, cocamide MEA, zinc carbonate, glycol distearate, dimethicone, cetyl alcohol, guar hydroxypropyltrimonium chloride, sodium xylenesulfonate, magnesium sulfate, sodium chloride, sodium benzoate, fragrance, DMDM hydantoin, mentha piperita (peppermint) oil, menthol, mentha arvensis leaf oil, magnesium carbonate hydroxide, benzyl alcohol, camellia sinensis leaf extract, yeast extract, lecithin, saccharomyces/magnesium ferment, biotin/folic acid/cyanocobalamin/niacinamide/pantothenic acid/pyridoxine/riboflavin/thiamine/yeast polypeptides, saccharomyces/iron ferment, saccharomyces/copper ferment, saccharomyces/silicon ferment, methylchloroisothiazolinone, saccharomyces/zinc ferment, methylisothiazolinone.

Questions (or comments)?

OTC - QUESTIONS SECTION

1-800-935-5273

SPL UNCLASSIFIED SECTION

Dist. by THE WELLA
CORPORATION, WOODLAND
HILLS, CA 91367

PRINCIPAL DISPLAY PANEL - 200 mL Bottle Label

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

NIOXIN_®

PYRITHIONE ZINC
DANDRUFF SHAMPOO

SCALP OPTIMIZING
CLEANSER

advanced
thinning

96974610

CLEARS SCALP
TO REDUCE DAMAGE
ON NEW HAIR

6.7 FL OZ (200 mL)

PRINCIPAL DISPLAY PANEL - 200 mL Bottle Label

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDC	Effective	Action	Document	Indexing SPL	Related label
69282-004-10	2022-12-22	C162847	48780-1	e4f33bdf-aa79-d8a0-e053-dadaa90a6e4e	Nioxin ® Scalp Optimizing Cleanser Advanced Thinning
69282-004-20	2022-12-22	C162847	48780-1	e4f33bdf-aa79-d8a0-e053-dadaa90a6e4e	Nioxin ® Scalp Optimizing Cleanser Advanced Thinning
69282-004-50	2022-12-22	C162847	48780-1	e4f33bdf-aa79-d8a0-e053-dadaa90a6e4e	Nioxin ® Scalp Optimizing Cleanser Advanced Thinning
69282-004-10	2022-07-29	C162847	48780-1	e4f33bdf-aa79-d8a0-e053-dadaa90a6e4e	Nioxin ® Scalp Optimizing Cleanser Advanced Thinning
69282-004-20	2022-07-29	C162847	48780-1	e4f33bdf-aa79-d8a0-e053-dadaa90a6e4e	Nioxin ® Scalp Optimizing Cleanser Advanced Thinning
69282-004-50	2022-07-29	C162847	48780-1	e4f33bdf-aa79-d8a0-e053-dadaa90a6e4e	Nioxin ® Scalp Optimizing Cleanser Advanced Thinning

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	SPL version
Pyrithione Zinc	ACTIVE INGREDIENT	R953O2RHZ5	1
Pyrithione Zinc	ACTIVE MOIETY	R953O2RHZ5	1
benzyl alcohol	INACTIVE INGREDIENT	LKG8494WBH	1
cetyl alcohol	INACTIVE INGREDIENT	936JST6JCN	1
coco monoethanolamide	INACTIVE INGREDIENT	C80684146D	1
dimethicone	INACTIVE INGREDIENT	92RU3N3Y1O	1
DMDM hydantoin	INACTIVE INGREDIENT	BYR0546TOW	1
glycol distearate	INACTIVE INGREDIENT	13W7MDN21W	1
green tea leaf	INACTIVE INGREDIENT	W2ZU1RY8B0	1
magnesium carbonate hydroxide	INACTIVE INGREDIENT	YQO029V1L4	1
magnesium sulfate	INACTIVE INGREDIENT	DE08037SAB	1
mentha arvensis leaf oil	INACTIVE INGREDIENT	1AEY1M553N	1
menthol, unspecified form	INACTIVE INGREDIENT	L7T10EIP3A	1
methylchloroisothiazolinone	INACTIVE INGREDIENT	DEL7T5QRPN	1
methylisothiazolinone	INACTIVE INGREDIENT	229D0E1QFA	1
peppermint oil	INACTIVE INGREDIENT	AV092KU4JH	1
sodium benzoate	INACTIVE INGREDIENT	OJ245FE5EU	1
sodium chloride	INACTIVE INGREDIENT	451W47IQ8X	1
sodium laureth-3 sulfate	INACTIVE INGREDIENT	BPV390UAP0	1
sodium lauryl sulfate	INACTIVE INGREDIENT	368GB5141J	1
sodium xylenesulfonate	INACTIVE INGREDIENT	G4LZF950UR	1
water	INACTIVE INGREDIENT	059QF0KO0R	1
yeast	INACTIVE INGREDIENT	3NY3SM6B8U	1
zinc carbonate	INACTIVE INGREDIENT	EQR32Y7H0M	1

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 24 matching rows.

Nioxin Scalp Optimizing Cleanser Advanced Thinning
Pyrithione Zinc
WATER
SODIUM LAURETH-3 SULFATE
SODIUM LAURYL SULFATE
COCO MONOETHANOLAMIDE
ZINC CARBONATE
GLYCOL DISTEARATE
DIMETHICONE
CETYL ALCOHOL
SODIUM XYLENESULFONATE
MAGNESIUM SULFATE, UNSPECIFIED FORM
SODIUM CHLORIDE
SODIUM BENZOATE
DMDM HYDANTOIN
PEPPERMINT OIL
MENTHOL, UNSPECIFIED FORM
MENTHA ARVENSIS LEAF OIL
MAGNESIUM CARBONATE HYDROXIDE
BENZYL ALCOHOL
GREEN TEA LEAF
YEAST
METHYLCHLOROISOTHIAZOLINONE
METHYLISOTHIAZOLINONE

NDC Codes#

Product NDC, Package NDC table
Product NDC	Package NDC
69282-004	69282-004-50, 69282-004-20, 69282-004-10

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 23 matching rows.

Name, UNII, Kind table
Name	UNII	Kind
WATER	059QF0KO0R	IACT
SODIUM LAURETH-3 SULFATE	BPV390UAP0	IACT
SODIUM LAURYL SULFATE	368GB5141J	IACT
COCO MONOETHANOLAMIDE	C80684146D	IACT
ZINC CARBONATE	EQR32Y7H0M	IACT
GLYCOL DISTEARATE	13W7MDN21W	IACT
DIMETHICONE	92RU3N3Y1O	IACT
CETYL ALCOHOL	936JST6JCN	IACT
SODIUM XYLENESULFONATE	G4LZF950UR	IACT
MAGNESIUM SULFATE, UNSPECIFIED FORM	DE08037SAB	IACT
SODIUM CHLORIDE	451W47IQ8X	IACT
SODIUM BENZOATE	OJ245FE5EU	IACT
DMDM HYDANTOIN	BYR0546TOW	IACT
PEPPERMINT OIL	AV092KU4JH	IACT
MENTHOL, UNSPECIFIED FORM	L7T10EIP3A	IACT
MENTHA ARVENSIS LEAF OIL	1AEY1M553N	IACT
MAGNESIUM CARBONATE HYDROXIDE	YQO029V1L4	IACT
BENZYL ALCOHOL	LKG8494WBH	IACT
GREEN TEA LEAF	W2ZU1RY8B0	IACT
YEAST	3NY3SM6B8U	IACT
METHYLCHLOROISOTHIAZOLINONE	DEL7T5QRPN	IACT
METHYLISOTHIAZOLINONE	229D0E1QFA	IACT
PYRITHIONE ZINC	R953O2RHZ5	ACTIB

Source Document#

Source XML

Inactive ingredient matches#

Inactive Ingredient Database values describe FDA-listed use contexts. The match method and ambiguity count are shown because ingredient names, routes, and dosage forms are not always unique. Browse recovered IID releases and source provenance.

Inactive ingredient links page 1 of 6 · 340 matching rows.

DailyMed ingredient, IID ingredient, UNII table
DailyMed ingredient	IID ingredient	UNII	Dosage form / route	Potency	Maximum daily exposure	Match
menthol, unspecified form	MENTHOL	L7T10EIP3A	TABLET / ORAL	0.58 mg		Exact identifier — unii candidate 24 equally ranked IID candidates
peppermint oil	PEPPERMINT OIL	AV092KU4JH	FILM, SOLUBLE / BUCCAL		3 mg	Exact identifier — unii candidate 21 equally ranked IID candidates
sodium benzoate	SODIUM BENZOATE	OJ245FE5EU	SYRUP / ORAL		80 mg	Exact identifier — unii candidate 35 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	TABLET / BUCCAL	5.18 mg		Exact identifier — unii candidate 42 equally ranked IID candidates
peppermint oil	PEPPERMINT OIL	AV092KU4JH	GUM, CHEWING / BUCCAL		526 mg	Exact identifier — unii candidate 21 equally ranked IID candidates
benzyl alcohol	BENZYL ALCOHOL	LKG8494WBH	SUSPENSION / AURICULAR (OTIC)	0.9 %w/v		Exact identifier — unii candidate 50 equally ranked IID candidates
benzyl alcohol	BENZYL ALCOHOL	LKG8494WBH	INJECTION, SUSPENSION / SOFT TISSUE		40 mg	Exact identifier — unii candidate 50 equally ranked IID candidates
benzyl alcohol	BENZYL ALCOHOL	LKG8494WBH	LOTION / TOPICAL		4000 mg	Exact identifier — unii candidate 50 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	CAPSULE, EXTENDED RELEASE / ORAL		166 mg	Exact identifier — unii candidate 42 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	GEL / VAGINAL	10 %w/w		Exact identifier — unii candidate 134 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	INJECTION, SOLUTION / INTRAMUSCULAR		1486 mg	Exact identifier — unii candidate 134 equally ranked IID candidates
peppermint oil	PEPPERMINT OIL	AV092KU4JH	SOLUTION / ORAL		53 mg	Exact identifier — unii candidate 21 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	INJECTION / INTRA-ARTERIAL		278 mg	Exact identifier — unii candidate 134 equally ranked IID candidates
magnesium sulfate	MAGNESIUM SULFATE	DE08037SAB	TABLET, COATED / ORAL	NA		Exact identifier — unii candidate 6 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	CAPSULE, COATED PELLETS / ORAL		1 mg	Exact identifier — unii candidate 42 equally ranked IID candidates
benzyl alcohol	BENZYL ALCOHOL	LKG8494WBH	INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION / INTRACAVERNOUS		18 mg	Exact identifier — unii candidate 50 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	INJECTION, SOLUTION, CONCENTRATE / INTRAOCULAR	0.86 %w/v		Exact identifier — unii candidate 134 equally ranked IID candidates
magnesium sulfate	MAGNESIUM SULFATE	DE08037SAB	SOAP / TOPICAL	0.2 %w/w		Exact identifier — unii candidate 6 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	GRANULE, FOR SUSPENSION / ORAL		162 mg	Exact identifier — unii candidate 134 equally ranked IID candidates
sodium benzoate	SODIUM BENZOATE	OJ245FE5EU	SUSPENSION/ DROPS / ORAL		23 mg	Exact identifier — unii candidate 35 equally ranked IID candidates
benzyl alcohol	BENZYL ALCOHOL	LKG8494WBH	INJECTION, POWDER, FOR SOLUTION / INTRAMUSCULAR	144 mg		Exact identifier — unii candidate 50 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	SUSPENSION/ DROPS / AURICULAR (OTIC)		3 mg	Exact identifier — unii candidate 134 equally ranked IID candidates
benzyl alcohol	BENZYL ALCOHOL	LKG8494WBH	INJECTION / INTRA-ARTICULAR	1 %w/v		Exact identifier — unii candidate 50 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	SUSPENSION / INTRAMUSCULAR	9 mg		Exact identifier — unii candidate 134 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	TABLET, DELAYED RELEASE / ORAL		97 mg	Exact identifier — unii candidate 134 equally ranked IID candidates
benzyl alcohol	BENZYL ALCOHOL	LKG8494WBH	INJECTION, SUSPENSION / INTRA-ARTICULAR		40 mg	Exact identifier — unii candidate 50 equally ranked IID candidates
sodium benzoate	SODIUM BENZOATE	OJ245FE5EU	PASTE / DENTAL	0.08 %w/w		Exact identifier — unii candidate 35 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	CAPSULE / ORAL		600 mg	Exact identifier — unii candidate 42 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	INJECTION, POWDER, FOR SOLUTION / INTRAPERITONEAL	226 mg		Exact identifier — unii candidate 134 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	INJECTION / RETROBULBAR		648 mg	Exact identifier — unii candidate 134 equally ranked IID candidates
menthol, unspecified form	MENTHOL	L7T10EIP3A	PASTE, DENTIFRICE / DENTAL	4.7 %w/w		Exact identifier — unii candidate 24 equally ranked IID candidates
peppermint oil	PEPPERMINT OIL	AV092KU4JH	TABLET / ORAL		28 mg	Exact identifier — unii candidate 21 equally ranked IID candidates
sodium laureth-3 sulfate	SODIUM LAURETH-3 SULFATE	BPV390UAP0	CAPSULE / ORAL	3.5 mg		Exact identifier — unii candidate 5 equally ranked IID candidates
benzyl alcohol	BENZYL ALCOHOL	LKG8494WBH	CREAM / VAGINAL	1 %w/w		Exact identifier — unii candidate 50 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	TABLET, EXTENDED RELEASE / ORAL	335.1 mg		Exact identifier — unii candidate 134 equally ranked IID candidates
menthol, unspecified form	MENTHOL	L7T10EIP3A	LOTION / TOPICAL	0.05 %w/w		Exact identifier — unii candidate 24 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	INJECTION / INFILTRATION		648 mg	Exact identifier — unii candidate 134 equally ranked IID candidates
sodium benzoate	SODIUM BENZOATE	OJ245FE5EU	POWDER, FOR SUSPENSION / ORAL		160 mg	Exact identifier — unii candidate 35 equally ranked IID candidates
cetyl alcohol	CETYL ALCOHOL	936JST6JCN	SUSPENSION / AURICULAR (OTIC)	1 %w/v		Exact identifier — unii candidate 20 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	SPONGE / TOPICAL	5 %w/w		Exact identifier — unii candidate 42 equally ranked IID candidates
benzyl alcohol	BENZYL ALCOHOL	LKG8494WBH	INJECTION / INTRA-ARTERIAL	0.9 %w/v		Exact identifier — unii candidate 50 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	INJECTION, SOLUTION / PARENTERAL		210 mg	Exact identifier — unii candidate 134 equally ranked IID candidates
menthol, unspecified form	MENTHOL	L7T10EIP3A	CONCENTRATE / ORAL	0.05 mg/5ml		Exact identifier — unii candidate 24 equally ranked IID candidates
sodium benzoate	SODIUM BENZOATE	OJ245FE5EU	GRANULE, FOR SUSPENSION / ORAL		120 mg	Exact identifier — unii candidate 35 equally ranked IID candidates
peppermint oil	PEPPERMINT OIL	AV092KU4JH	POWDER / SUBLINGUAL		1 mg	Exact identifier — unii candidate 21 equally ranked IID candidates
menthol, unspecified form	MENTHOL	L7T10EIP3A	SOLUTION, CONCENTRATE / ORAL	0.5 mg/1ml		Exact identifier — unii candidate 24 equally ranked IID candidates
peppermint oil	PEPPERMINT OIL	AV092KU4JH	SOLUTION / DENTAL	0.04 %v/v		Exact identifier — unii candidate 21 equally ranked IID candidates
sodium benzoate	SODIUM BENZOATE	OJ245FE5EU	SOLUTION / TOPICAL	0.1 %w/v		Exact identifier — unii candidate 35 equally ranked IID candidates
benzyl alcohol	BENZYL ALCOHOL	LKG8494WBH	SOLUTION / INTRAVENOUS		242 mg	Exact identifier — unii candidate 50 equally ranked IID candidates
sodium lauryl sulfate	SODIUM LAURYL SULFATE	368GB5141J	OINTMENT / TOPICAL		14 mg	Exact identifier — unii candidate 42 equally ranked IID candidates
peppermint oil	PEPPERMINT OIL	AV092KU4JH	OINTMENT / TOPICAL	0.2 %w/w		Exact identifier — unii candidate 21 equally ranked IID candidates
benzyl alcohol	BENZYL ALCOHOL	LKG8494WBH	INJECTION, SOLUTION / INTRAVENOUS		400 mg	Exact identifier — unii candidate 50 equally ranked IID candidates
sodium benzoate	SODIUM BENZOATE	OJ245FE5EU	TABLET, FILM COATED / ORAL		1 mg	Exact identifier — unii candidate 35 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	INJECTION / INTRACAVITARY	0.82 %w/v		Exact identifier — unii candidate 134 equally ranked IID candidates
benzyl alcohol	BENZYL ALCOHOL	LKG8494WBH	INJECTION, SUSPENSION / INTRALESIONAL		20 mg	Exact identifier — unii candidate 50 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	INJECTION, SUSPENSION / INTRALESIONAL		13 mg	Exact identifier — unii candidate 134 equally ranked IID candidates
benzyl alcohol	BENZYL ALCOHOL	LKG8494WBH	SHAMPOO / TOPICAL	1.25 %w/w		Exact identifier — unii candidate 50 equally ranked IID candidates
benzyl alcohol	BENZYL ALCOHOL	LKG8494WBH	INJECTION / SUBCONJUNCTIVAL		252 mg	Exact identifier — unii candidate 50 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	INJECTION, SOLUTION, CONCENTRATE / INTRAVENOUS	0.86 %w/v		Exact identifier — unii candidate 134 equally ranked IID candidates
sodium chloride	SODIUM CHLORIDE	451W47IQ8X	LIQUID / INTRAMUSCULAR		17 mg	Exact identifier — unii candidate 134 equally ranked IID candidates

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
b67c989b-8963-9576-e053-2995a90aef3a			4a64cea8-5ae1-464c-b9b1-9b438490f83c	2022-12-20	Warnings	Exact identifier spl set id: 4a64cea8-5ae1-464c-b9b1-9b438490f83c

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.