Multi-Symptom Cold Relief
- Manufacturer
- Unifirst First Aid Corporation
- Effective date
- 2025-09-08
- Label type
- HUMAN OTC DRUG LABEL
- Version
- 6
- Source
- full-release
- Hydrated at
- 2026-06-01 01:13:06
Label at a glance#
Contacts and useful links#
Label contents#
Full prescribing information#
SPL UNCLASSIFIED SECTION
Drug Facts
OTC - ACTIVE INGREDIENT SECTION
Active ingredients (in each caplet)
Acetaminophen 325 mg
Dextromethorphan HBr 10 mg
Guaifenesin 100 mg
Phenylephrine HCl 5 mg
OTC - PURPOSE SECTION
Purpose
Pain reliever/fever reducer
Cough suppressant
Expectorant
Nasal decongestant
INDICATIONS & USAGE SECTION
Uses
Temporarily relieves these symptoms due to the common cold
- headache
- nasal congestion
- cough
- minor aches and pains
- sore throat
- sinus congestion and pressure
- helps loosen phlegm (mucus) and thin bronchial secretions to drain bronchial tubes and make cough more productive
Temporarily reduces fever.
WARNINGS SECTION
Warnings
Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take:
- more than 4,000 mg of acetaminophen in 24 hours
- with other drugs containing acetaminophen
- 3 or more alcoholic drinks every day while using this product
Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include:
- skin reddening
- blisters
- rash
If a skin reaction occurs, stop use and seek medical help right away.
Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.
OTC - DO NOT USE SECTION
Do not use
- with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
- if you have ever had an allergic reaction to this product or any of its ingredients
- if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
OTC - ASK DOCTOR SECTION
Ask a doctor before use if you have
- liver disease
- heart disease
- high blood pressure
- thyroid disease
- diabetes
- difficulty in urination due to enlargement of the prostate gland
- cough that occurs with too much phlegm (mucus)
- persistent or chronic cough that lasts as occurs with smoking, asthma, chronic bronchitis, or emphysema
OTC - ASK DOCTOR/PHARMACIST SECTION
Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin.
OTC - WHEN USING SECTION
When using this product do not exceed recommended dosage.
OTC - STOP USE SECTION
Stop use and ask a doctor if
- nervousness, dizziness, or sleeplessness occur
- pain, cough, or nasal congestion gets worse or lasts more than 7 days
- fever gets worse or lasts more than 3 days
- redness or swelling is present
- new symptoms occur
- cough comes back or occurs with rash or headache that lasts.
These could be signs of a serious condition.
OTC - PREGNANCY OR BREAST FEEDING SECTION
If pregnant or breast-feeding, ask a health professional before use.
OTC - KEEP OUT OF REACH OF CHILDREN SECTION
Keep out of reach of children.
In case of overdose, get medical help or contact a Poison Control Center right away. Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.
DOSAGE & ADMINISTRATION SECTION
Directions
- do not take more than directed
Adults and children: (12 years and over)
- take 2 caplets every 4 hours
- not to take more than 10 caplets in 24 hours
Children under 12 years: ask a doctor
OTHER SAFETY INFORMATION
Other information
- store at 25°C (77°F); excursions permitted between 15°-30°C (59°-86°F)
- tamper evident sealed packets
- do not use any opened or torn packets
INACTIVE INGREDIENT SECTION
Inactive ingredients corn starch, crospovidone, FD&C yellow # 6 aluminum lake, magnesium stearate, maltodextrin, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone,silicon dioxide, sodium starch glycolate, stearic acid, talc, titanium dioxide
OTC - QUESTIONS SECTION
Questions or comments? 1-800-869-6970
PACKAGE LABEL.PRINCIPAL DISPLAY PANEL
Multi-Symptom Cold Relief™
Pull to Open
Tire Para Abrir
Acetaminophen / Acetaminofeno 325 mg
Dextromethorphan HBr / Hidrobromuro de dextrometorfano 10 mg
Guaifenesin / Guaifenesina 100 mg
Phenylephrine HCl / Hidrocloruro de fenilefrina 5 mg
Green Guard®
Pain reliever/Fever reducer
Multi-Symptom Relief
Alivia el dolor/Reduce la fiebre
Alivia multisintomas
Distributed by Green Guard®
St Louis, MO 63045
40 Packets of 2 Caplets
80 Caplets
Order #2580
DailyMed RxNorm Mappings#
| RxCUI | RxNorm string | TTY | SPL version |
|---|---|---|---|
| 1098435 | acetaminophen 325 MG / dextromethorphan HBr 10 MG / guaiFENesin 100 MG / phenylephrine HCl 5 MG Oral Tablet | PSN | 6 |
| 1098435 | acetaminophen 325 MG / dextromethorphan hydrobromide 10 MG / guaifenesin 100 MG / phenylephrine hydrochloride 5 MG Oral Tablet | SCD | 6 |
| 1098435 | APAP 325 MG / Dextromethorphan Hydrobromide 10 MG / Guaifenesin 100 MG / Phenylephrine Hydrochloride 5 MG Oral Tablet | SY | 6 |
DailyMed Pharmacologic Classes#
| Class | Version | Type | Effective |
|---|---|---|---|
| DEXTROMETHORPHAN Pharmacologic Class Indexing | 2 | Indexing - Pharmacologic Class | 20180813 |
| GUAIFENESIN Pharmacologic Class Indexing | 1 | Indexing - Pharmacologic Class | 20211129 |
| PHENYLEPHRINE Pharmacologic Class Indexing | 2 | Indexing - Pharmacologic Class | 20180813 |
DailyMed Package Descriptions#
| Package NDC | Product | Description | Form | Quantity | Strength | SPL version |
|---|---|---|---|---|---|---|
| 47682-047-47 | Multi-Symptom Cold Relief | 100 in 1 BOX | TABLET, FILM COATED | 100 | 6 | |
| 47682-047-80 | Multi-Symptom Cold Relief | 40 in 1 BOX | TABLET, FILM COATED | 40 | 6 | |
| 47682-047-99 | Multi-Symptom Cold Relief | 2 in 1 PACKET | TABLET, FILM COATED | 2 | 6 |
Products#
Every source-derived product name is available through these pages.
- Multi-Symptom Cold Relief
- Acetaminophen, Dextromethorphan HBr, Phenylephrine HCl , Guaifenesin, ,
- POVIDONE
- SILICON DIOXIDE
- MALTODEXTRIN
- DEXTROMETHORPHAN HYDROBROMIDE
- DEXTROMETHORPHAN
- STARCH, CORN
- MAGNESIUM STEARATE
- SODIUM STARCH GLYCOLATE TYPE A POTATO
- TITANIUM DIOXIDE
- STEARIC ACID
- GUAIFENESIN
- MICROCRYSTALLINE CELLULOSE
- TALC
- POLYVINYL ALCOHOL, UNSPECIFIED
- ACETAMINOPHEN
- CROSPOVIDONE
- PHENYLEPHRINE HYDROCHLORIDE
- PHENYLEPHRINE
- FD&C YELLOW NO. 6
- POLYETHYLENE GLYCOL, UNSPECIFIED
NDC Codes#
| Product NDC | Package NDC |
|---|---|
| 47682-047 | 47682-047-99, 47682-047-80, 47682-047-47 |
Ingredients#
Every source-derived ingredient row is available through these pages.
Source Document#
openFDA label cross-check#
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| Multi-Symptom Cold Relief | ACETAMINOPHEN, DEXTROMETHORPHAN HBR, PHENYLEPHRINE HCL , GUAIFENESIN, , | Unifirst First Aid Corporation | e6ea6faf-baff-a130-e053-2a95a90a085a | 2025-09-08 | Warnings | 47682-047-99 47682-047-80 47682-047-47 47682-047 47682004799 47682004747 47682004780 3e4c8eb0-708e-774b-e063-6294a90a8436 e6ea6faf-baff-a130-e053-2a95a90a085a |
Reported adverse events (FAERS/openFDA)#
Adverse event summaries are temporarily unavailable. Other product information remains available.
